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Clinical trials for Essential hypertension

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
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    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    235 result(s) found for: Essential hypertension. Displaying page 1 of 12.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2004-003955-37 Sponsor Protocol Number: CL3-05590-022 Start Date*: 2005-03-29
    Sponsor Name:INSTITUT DE RECHERCHES INTERNATIONALES SERVIER
    Full Title: Efficacy of perindopril/indapamide combination on coronary Pet Scan parameters. A 6 month, open non controlled stydy in hypertensive patients
    Medical condition: Essential arterial hypertension
    Disease: Version SOC Term Classification Code Term Level
    6.1 10015488 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2007-000310-36 Sponsor Protocol Number: 2542 Start Date*: 2007-04-05
    Sponsor Name:Radboud University Medical Center Njmegen
    Full Title: Does statin therapy reduce sympathoexcitation in hypertension
    Medical condition: hypertension and sympathoexcitation
    Disease: Version SOC Term Classification Code Term Level
    9.1 10020782 Hypertension NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2007-000690-34 Sponsor Protocol Number: 0954A-327 Start Date*: 2007-05-29
    Sponsor Name:Merck Sharp & Dohme OÜ
    Full Title: A Randomized, Double-Blind, Active Comparator Study to Evaluate the Antihypertensive Efficacy and Safety of Losartan/HCTZ Combination as Compared to Losartan Monotherapy in Pediatric Patients With ...
    Medical condition: Essential Hypertension
    Disease: Version SOC Term Classification Code Term Level
    9.1 10015488 Essential hypertension LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: EE (Prematurely Ended) FI (Prematurely Ended) LT (Prematurely Ended) HU (Completed) DE (Completed) GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-016738-28 Sponsor Protocol Number: ALISEI Start Date*: 2009-12-11
    Sponsor Name:AZIENDA OSPEDALIERA PISANA
    Full Title: Phase IV prospective, randomized, open with blind endpoints, parallel group study to evaluate the effect of Aliskiren on endothelial dysfunction in patients with essential hypertension
    Medical condition: essential hypertension
    Disease: Version SOC Term Classification Code Term Level
    12.0 10015488 Essential hypertension LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-000631-25 Sponsor Protocol Number: 2007-000631-25 Start Date*: 2010-06-08
    Sponsor Name:KAROLINSKA INSTITUTET
    Full Title: THE ANTITTHROMBOTIC EFFECTS OF DOXAZOSIN AND RAMIPRIL IN ESSENTIAL HYPERTENSION
    Medical condition: ESSENTIAL HYPERTENSION
    Disease: Version SOC Term Classification Code Term Level
    12.1 10015488 Essential hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-017831-16 Sponsor Protocol Number: 26169 Start Date*: 2010-07-15
    Sponsor Name:Institute of pharmacology, Aarhus university
    Full Title: Effects of 6 months intensive vasodilating treatment on vascular resistance and coronary flow reserve in hypertensive patients
    Medical condition: Essential Hypertension and changes in the vasculature related to high blood pressure.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10015488 Essential hypertension LLT
    12.1 10015489 Essential hypertension, benign LLT
    12.1 10015491 Essential hypertension, unspecified LLT
    12.1 10020772 Hypertension LLT
    12.1 10020775 Hypertension arterial LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-004938-16 Sponsor Protocol Number: 00-MEP-04 Start Date*: 2008-02-19
    Sponsor Name:Astellas Pharma Europe B.V.
    Full Title: A RANDOMISED, DOUBLE-BLIND STUDY TO COMPARE THE EFFECT ON SYMPATHETIC ACTIVITY AND HEMODYNAMIC PROFILE OF BARNIDIPINE AND AMLODIPINE IN PATIENTS WITH MILD TO MODERATE ESSENTIAL HYPERTENSION.
    Medical condition: Mild to moderate hypertension
    Disease: Version SOC Term Classification Code Term Level
    9.1 10015488 Essential hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-003144-23 Sponsor Protocol Number: PANDA Start Date*: 2014-02-03
    Sponsor Name:King's College London [...]
    1. King's College London
    2. Guy's and St Thomas' NHS Foundation Trust
    Full Title: Pregnancy And chronic hypertension: NifeDipine or labetalol as Antihypertensive treatment
    Medical condition: Chronic hypertension in pregnancy
    Disease: Version SOC Term Classification Code Term Level
    16.1 10047065 - Vascular disorders 10036695 Primary hypertension LLT
    16.1 10047065 - Vascular disorders 10039834 Secondary hypertension PT
    16.1 10047065 - Vascular disorders 10015488 Essential hypertension PT
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-000077-22 Sponsor Protocol Number: CL2-90652-001 Start Date*: Information not available in EudraCT
    Sponsor Name:Institut de Recherches Internationales Servier
    Full Title: Acceptability, safety, pharmacokinetics and effects on blood pressure of a daily dose of 0.025 to 0.135 milligram per kilogram of S 90652, a paediatric formulation of perindopril, in 2-16 years old...
    Medical condition: Arterial hypertension
    Disease: Version SOC Term Classification Code Term Level
    5.1 10020782 PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: BE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2007-002422-29 Sponsor Protocol Number: 1235.8 Start Date*: 2007-10-19
    Sponsor Name:Boehringer Ingelheim Ltd.
    Full Title: An open-label follow-up trial of the efficacy and safety of chronic administration of the combination of telmisartan 40mg + amlodipine 10mg or the combination of telmisartan 80mg + amlodipine 10mg ...
    Medical condition: essential hypertension
    Disease: Version SOC Term Classification Code Term Level
    9.1 10015488 Essential hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Completed) GB (Completed) AT (Completed) CZ (Completed) ES (Completed) IT (Completed) BG (Completed) SK (Completed)
    Trial results: View results
    EudraCT Number: 2008-005432-32 Sponsor Protocol Number: 08.0113 Start Date*: 2009-06-02
    Sponsor Name:St. George's University of London (SGUL)
    Full Title: Effects of an Angiotensin Receptor Antagonist Candesartan versus a calcium channel blocker Amlodipine on Microvascular Rarefaction, Endothelial Dysfunction and Microalbuminuria in Essential Hyperte...
    Medical condition: Essential hypertension
    Disease: Version SOC Term Classification Code Term Level
    14.1 10047065 - Vascular disorders 10004254 Benign essential hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-002410-19 Sponsor Protocol Number: 1235.7 Start Date*: 2007-09-26
    Sponsor Name:Boehringer Ingelheim bv
    Full Title: An open label follow-up trial of the efficacy and safety of chronic administration of the combination of telmisartan 40mg + amlodipine 5mg or the combination of telmisartan 80mg + amlodipine 5mg ta...
    Medical condition: essential hypertension
    Disease: Version SOC Term Classification Code Term Level
    9.1 10015488 Essential hypertension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed) FI (Completed) BE (Completed) SE (Completed) DK (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2007-007026-22 Sponsor Protocol Number: CL2-09490-157 Start Date*: 2008-03-28
    Sponsor Name:Institut de Recherches Internationales Servier
    Full Title: Assessment of the effects on 24-hour ambulatory blood pressure and the safety of a once-a-day oral 8 mg perindopril morning administration versus evening administration in hypertensive patients. An...
    Medical condition: Essential arterial hyperpertension
    Disease: Version SOC Term Classification Code Term Level
    9.1 10015488 Essential hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-011156-21 Sponsor Protocol Number: CCFM 119/209 Start Date*: 2011-04-28
    Sponsor Name:FONDAZIONE MONZINO CENTRO CARDIOLOGICO
    Full Title: Effects of beta-blockers on exercise performance in uncomplicated hypertension
    Medical condition: Non complicated arterial hypertension
    Disease: Version SOC Term Classification Code Term Level
    14.0 10047065 - Vascular disorders 10015488 Essential hypertension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-001131-31 Sponsor Protocol Number: FHC-1-2012 Start Date*: 2012-06-14
    Sponsor Name:Department of Medical Research
    Full Title: Effekts of nebivolol on the nitric oxide system in patients with essentiel hypertension
    Medical condition: Essential Hypertension
    Disease: Version SOC Term Classification Code Term Level
    14.1 10047065 - Vascular disorders 10015488 Essential hypertension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-001014-37 Sponsor Protocol Number: ALTUM Start Date*: 2020-08-13
    Sponsor Name:OSPEDALE SAN RAFFAELE
    Full Title: Pharmacogenetics of hypertension: randomized monocentric study in patients with essential hypertension and treated with Spironolactone or Torasemide
    Medical condition: Essential hypertension
    Disease: Version SOC Term Classification Code Term Level
    22.1 10047065 - Vascular disorders 10015489 Essential hypertension, benign LLT
    21.1 10047065 - Vascular disorders 10015488 Essential hypertension PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-019524-31 Sponsor Protocol Number: REC15/2375–IT–CL 0332 Start Date*: 2010-06-08
    Sponsor Name:RECORDATI
    Full Title: Safety of an ACE-I/CCB fixed combination (Lercanidipine/Enalapril) in elderly hypertensive patients not adequately controlled by CCB monotherapy
    Medical condition: Essential Hypetension
    Disease: Version SOC Term Classification Code Term Level
    12.1 10015488 Essential hypertension LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2006-001823-20 Sponsor Protocol Number: CMA-0601-PR-0004 Start Date*: 2006-06-22
    Sponsor Name:CHIESI
    Full Title: A twelve-week, multicentre, double blind, randomised, parallel group, clinical study to assess the antihypertensive efficacy of delapril 15 mg b.i.d. and 30 mg b.i.d. versus lisinopril and placebo
    Medical condition: hypertension
    Disease: Version SOC Term Classification Code Term Level
    9.1 10015488 Essential hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2005-004380-32 Sponsor Protocol Number: 2005-1F Start Date*: 2005-09-15
    Sponsor Name:UNIVERSITA DEGLI STUDI DI PAVIA
    Full Title: RANDOMISED, CONTROLLED STUDY WITH A BLINDED END-POINT TO EVALUATE BY MEANS OF 24-HOUR AMBULATORY BLOOD PRESSURE MONITORING THE ANTIHYPERTENSIVE ACTIVITY OF OLMESARTAN 20 MG IN COMPARISON WITH THA...
    Medical condition: Hypertension
    Disease: Version SOC Term Classification Code Term Level
    9.1 10015488 Essential hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-005082-19 Sponsor Protocol Number: RB23EZ Start Date*: 2006-12-06
    Sponsor Name:Research Innovation Services, University of Nottingham
    Full Title: Effect of an angiotensin receptor antagonist on cerebral blood flow, cerebral perfusion pressure, and systemic and peripheral haemodynamics in patients with recent stroke.
    Medical condition: Patients who have hypertension in the context of recent stroke.
    Disease: Version SOC Term Classification Code Term Level
    8.1 10015488 Essential hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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