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Clinical trials for Folic acid

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    201 result(s) found for: Folic acid. Displaying page 1 of 11.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2004-002306-29 Sponsor Protocol Number: RLH 2786 Start Date*: 2004-12-21
    Sponsor Name:Royal Liverpool and Broadgreen University Hospitals NHS Trust
    Full Title: Psoriasis, Folic Acid Supplementation and Plasma Homocysteine Levels
    Medical condition: Psoriasis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2008-000599-25 Sponsor Protocol Number: 3010 Start Date*: 2008-05-09
    Sponsor Name:TweeSteden Hospital
    Full Title: Iron and Folic acid v.s. Iron solely in the treatment of post partum anaemia, effects on haemoglobin and health status
    Medical condition: post partum anemia is generally treated by ferrous fumarate. It is unclear whether the addition of folic acid to ferrous fumarate in the treatment of anaemia could accelerate the increase of haemog...
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2005-000333-38 Sponsor Protocol Number: Hcy2005 Start Date*: 2005-05-25
    Sponsor Name:Organisation name was not entered
    Full Title: A randomized placebo-controlled trial to investigate blood pressure lowering effects of folic acid in patients with borderline hypertension.
    Medical condition: Patients with hyperhomocysteinemia and high-normal blood pressure, otherwise healthy
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-003703-21 Sponsor Protocol Number: 5802003 Start Date*: 2005-01-28
    Sponsor Name:Semmelweis University
    Full Title: The role of hyperhomocysteinemia in the genesis of atherothrombotic vascular disease
    Medical condition: Established cardiovascular disease with elevated levels of homocystein
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-004334-25 Sponsor Protocol Number: FARM6KWTCT Start Date*: 2008-08-06
    Sponsor Name:AZIENDA OSPEDALIERA ISTITUTI OSPITALIERI DI VERONA
    Full Title: Efficacy of folic acid at high doses in preventing congenital anomalies. Randomized clinical trial in fertile women who plan a pregnancy: folic acid 4mg vs 0.4mg.
    Medical condition: Prevention of congenital anomalies in pregnancy.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10016849 Foetal complications HLGT
    Population Age: Adults Gender: Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-000551-15 Sponsor Protocol Number: MTXa54 Start Date*: 2005-09-05
    Sponsor Name:University of Dundee
    Full Title: Effect of folic acid supplementation and allopurinol on endothelial function in patients with rheumatoid arthritis treated with methotrexate
    Medical condition: Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory polyarthritis associated with excess cardiovascular (CV) mortality. Hyperhomocysteinaemia is recognized as an independent CV risk fact...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2012-001918-42 Sponsor Protocol Number: 2009-107(Canadian) Start Date*: 2014-01-17
    Sponsor Name:Ottawa Hospital Research Institute
    Full Title: Effect of folic acid supplementation in pregnancy on preeclampsia - Folic Acid Clinical Trial (FACT) A randomized, double-blind, placebo-controlled, Phase III, international multi-centre study of 4...
    Medical condition: pre-eclampsia
    Disease: Version SOC Term Classification Code Term Level
    20.0 10036585 - Pregnancy, puerperium and perinatal conditions 10036485 Pre-eclampsia PT
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-005178-55 Sponsor Protocol Number: 117/2005/U/Sper Start Date*: 2005-11-24
    Sponsor Name:AZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI
    Full Title: Folic acid and reduction of the cardiovascular risk from iperomicisteinemia in the patients subordinates to liver transplant.
    Medical condition: Reduction of the overomocisteinemie
    Disease: Version SOC Term Classification Code Term Level
    9.1 10051286 Hyperhomocysteinaemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-004246-41 Sponsor Protocol Number: RG_13-198 Start Date*: 2015-01-26
    Sponsor Name:Sandwell and West Birmingham Hospitals NHS Trust [...]
    1. Sandwell and West Birmingham Hospitals NHS Trust
    2. University of Birmingham
    Full Title: A phase III randomised study of folic acid supplementation in the management of menopausal symptoms in cancer survivors and healthy postmenopausal women
    Medical condition: Menopause Symptoms
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004872 10027311 Menopause flushing LLT
    18.0 10041244 - Social circumstances 10028812 Natural menopause LLT
    18.0 10041244 - Social circumstances 10027308 Menopause PT
    18.0 10041244 - Social circumstances 10051775 Postmenopause PT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2018-003619-23 Sponsor Protocol Number: 6630-4200-42 Start Date*: 2019-11-29
    Sponsor Name:MEDICE Arzneimittel Pütter GmbH & Co. KG
    Full Title: EFFICACY AND SAFETY OF A PARENTERALLY ADMINISTERED FIXED VITAMIN COMBINATION (VITAMIN B6, B12 AND FOLIC ACID) ON VITAMIN B12 STATUS AND METHYLATION CAPACITY IN COBALAMIN DEFICIENCY COMPARED TO ORAL...
    Medical condition: vitamin B12 deficiency
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-004513-33 Sponsor Protocol Number: OCTUMI-02 Start Date*: 2008-05-08
    Sponsor Name:University of Oxford
    Full Title: Comparative Evaluation of QUEtiapine-Lamotrigine combination versus quetiapine monotherapy (and folic acid versus placebo) in patients with bipolar depression
    Medical condition: Bipolar depression
    Disease: Version SOC Term Classification Code Term Level
    13.1 10037175 - Psychiatric disorders 10004936 Bipolar depression LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2016-001193-15 Sponsor Protocol Number: FASTERCC-001 Start Date*: 2016-07-06
    Sponsor Name:Department of Oncology, Aarhus University Hospital
    Full Title: Folic acid supplement versus placebo for treating mucositis adverse events in metastatic renal cell carcinoma patients receiving targeted therapy (FASTERCC). A randomized, double-blind, phase II ...
    Medical condition: Mucositis (nasal, oral, pharyngeal, anal, or genital) is often experienced in relation to TKI and mTOR inhibitor treatment of metastatic renal cell carcinoma patients. The present trial will assess...
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004872 10064282 Vaginal mucositis LLT
    20.0 100000004856 10028130 Mucositis oral LLT
    20.0 100000004856 10065721 Anal mucositis LLT
    20.0 100000004867 10028127 Mucositis LLT
    20.0 100000004855 10065881 Pharyngeal mucositis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2009-014469-19 Sponsor Protocol Number: RECOVERY[OCTUMI-4] Start Date*: 2010-08-17
    Sponsor Name:University of Oxford [...]
    1. University of Oxford
    2.
    Full Title: OCTUMI-4: Evaluation of Mirtazapine and Folic Acid for Schizophrenia: A randomised, double-blind, 2x2 factorial trial
    Medical condition: Schizophrenia
    Disease: Version SOC Term Classification Code Term Level
    14.1 10037175 - Psychiatric disorders 10039626 Schizophrenia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) FI (Completed) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-003325-10 Sponsor Protocol Number: 1.01 Start Date*: 2012-08-10
    Sponsor Name:VU University Medical Center
    Full Title: A randomized controlled trail on the effects of periconceptional and prenatal folic acid supplementation on congenital anomalies and preterm birth
    Medical condition: congenital anomalies
    Disease: Version SOC Term Classification Code Term Level
    14.1 10036585 - Pregnancy, puerperium and perinatal conditions 10004953 Birth premature LLT
    14.1 10010331 - Congenital, familial and genetic disorders 10007607 Cardiac septal defects congenital HLT
    14.1 10010331 - Congenital, familial and genetic disorders 10041524 Spina bifida PT
    Population Age: Adults Gender: Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-015403-95 Sponsor Protocol Number: NS10364-3 Start Date*: 2010-02-11
    Sponsor Name:Faculty Hospital Hradec Králové
    Full Title: A pilot trial of noninvasive assessment of methotrexate hepatotoxicity in the course of pharmacokinetically guided pharmacotherapy of psoriasis with methotrexate and folic acid
    Medical condition: moderate-severe and severe plaque psoriasis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-005666-37 Sponsor Protocol Number: PrefoDIP Start Date*: 2012-10-17
    Sponsor Name:ZAMBON ITALIA
    Full Title: Evaluation of the effect exerted by 5-methyltetrahydrofolate (5-MTHF) and folic acid in postmenopausal women
    Medical condition: The study evaluates the effects of different forms of folates on cardiovascular risk factors in postmenopausal patients
    Disease: Version SOC Term Classification Code Term Level
    14.1 10041244 - Social circumstances 10051775 Postmenopause PT
    Population Age: Adults Gender: Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-005643-26 Sponsor Protocol Number: PrefoCir2 Start Date*: 2012-03-15
    Sponsor Name:ZAMBON ITALIA
    Full Title: Cross-over pharmacokinetic study and pharmacodynamics of 2 different folate (5-MTHF and folic acid) in patients with liver cirrhosis with viral etiology. A randomized, open-label trial.
    Medical condition: In all cases of folate deficiency due to increased demand, poor absorption, inadequate dietary intake and reduced utilization of the vitamin in patients with viral liver cirrhosis.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10047457 Viral hepatitis C LLT
    14.1 10021881 - Infections and infestations 10047450 Viral hepatitis B LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-002811-29 Sponsor Protocol Number: PDX-008 Start Date*: 2006-11-10
    Sponsor Name:Allos Therapeutics, Inc.
    Full Title: A Multi-center Phase 2 Open-label Study of (RS)-10-Propargyl-10-Deazaaminopterin (pralatrexate) with Vitamin B12 and Folic Acid Supplementation in Patients with Relapsed or Refractory Peripheral T-...
    Medical condition: Phase 2 Open-label Study of (RS)-10-Propargyl-10-Deazaaminopterin (pralatrexate) with Vitamin B12 and Folic Acid Supplementation in Patients with Relapsed or Refractory Peripheral T-cell Lymphoma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) IT (Completed) GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-000614-21 Sponsor Protocol Number: 7168K01 Start Date*: 2007-08-09
    Sponsor Name:Zambon Group S.p.A
    Full Title: A multicentre, open-label study to evaluate the efficacy and safety of 5-MTHF administration, added on to the individual established therapy, on plasma homocysteine levels in patients with congenit...
    Medical condition: homocystinuria
    Disease: Version SOC Term Classification Code Term Level
    8.1 10020365 pref
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: AT (Completed) SK (Completed) HU (Completed) GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-004311-20 Sponsor Protocol Number: GU20151201 Start Date*: 2016-03-30
    Sponsor Name:Gothenburg University
    Full Title: Effect of vitamin B substitution on plasma NFL and neurocognitive performance in HIV-infected individuals with increased plasma homocysteine
    Medical condition: HIV
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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