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Clinical trials for Healthy Volunteers

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44341   clinical trials with a EudraCT protocol, of which   7370   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    1,162 result(s) found for: Healthy Volunteers. Displaying page 1 of 59.
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    EudraCT Number: 2005-000974-29 Sponsor Protocol Number: TH0501 Start Date*: 2005-04-01
    Sponsor Name:Boots Healthcare International Limited
    Full Title: An open label, oral bioavailability study to determine the levels of Amylmetacresol BP (AMC) and 2,4-dichlorobenzyl alcohol (DCBA) in the saliva of healthy volunteers after a single oral dose of S...
    Medical condition: AMC and DCBA are indicated for the symptomatic relief of mouth and throat infections.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-005043-16 Sponsor Protocol Number: DDD17FPV Start Date*: 2020-02-18
    Sponsor Name:KU Leuven - Drug Delivery and Disposition
    Full Title: Impact of stomach motility on the gastrointestinal behavior of fosamprenavir in healthy volunteers
    Medical condition: Healthy volunteers
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2019-001496-36 Sponsor Protocol Number: DDD19CRCSUL Start Date*: 2019-07-15
    Sponsor Name:KU Leuven
    Full Title: The intestinal disposition of sulindac in healthy volunteers
    Medical condition: Healthy volunteers
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2011-001756-12 Sponsor Protocol Number: UCL-2010-412 Start Date*: 2012-04-27
    Sponsor Name:Cliniques Universitaires Saint Luc - UCL
    Full Title: Surrogate markers evaluation in pre-demented Alzheimer’s disease patients and healthy elderly controls
    Medical condition: Healthy volunteers and Mild Cognitive Impaired patients
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-002830-30 Sponsor Protocol Number: DDD14JRindi Start Date*: 2014-12-24
    Sponsor Name:KU Leuven - Drug Delivery & Disposition
    Full Title: Supersaturation and precipitation of indinavir in the stomach of healthy human volunteers
    Medical condition: Healthy human volunteers (administration of a Protease inhibitor)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2013-004636-29 Sponsor Protocol Number: DDD13DICLO Start Date*: 2014-02-04
    Sponsor Name:KU Leuven - Drug Delivery & Disposition
    Full Title: Supersaturation and precipitation of diclofenac in the stomach of healthy human volunteers
    Medical condition: Healthy human volunteers (administration of a Non-Steroidal Anti-Inflammatory Drug)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2011-004811-21 Sponsor Protocol Number: s53584 Start Date*: 2011-11-07
    Sponsor Name:UZLeuven
    Full Title: The effect of Sildenafil citrate (Viagra ®) on stomach motility, gastric emptying and food intake in healthy volunteers
    Medical condition: study is conducted on healthy volunteers, no medical condition is investigated
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2013-001715-76 Sponsor Protocol Number: FTB13-SMV01 Start Date*: 2013-09-05
    Sponsor Name:KU Leuven-Drug Delivery and Disposition
    Full Title: Gastrointestinal behavior of simvastatin in healthy volunteers
    Medical condition: Healthy volunteers (administration of a hypolipidemic drug)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2016-001156-22 Sponsor Protocol Number: DDD16APREPITANT Start Date*: 2016-07-19
    Sponsor Name:KU Leuven - Drug Delivery and Disposition
    Full Title: The gastrointestinal behavior of aprepitant in healthy volunteers
    Medical condition: healthy human volunteers (administration of an drug against nausea and vomiting
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2011-005863-25 Sponsor Protocol Number: FTB-11-TFV01 Start Date*: 2012-04-26
    Sponsor Name:Katholieke Universiteit Leuven - Pharmacotechnology and Biopharmacy
    Full Title: Gastrointestinal behavior of tenofovir DF in healthy volunteers
    Medical condition: healthy volunteers (administration of antiviral drug)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2013-005594-51 Sponsor Protocol Number: FTB14-ABA01 Start Date*: 2014-04-02
    Sponsor Name:KU Leuven
    Full Title: Gastrointestinal behavior of abirateronacetaat in healthy volunteers
    Medical condition: healthy volunteers (administration of an androgen synthesis inhibitor)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2021-000594-81 Sponsor Protocol Number: S65020 Start Date*: 2021-05-07
    Sponsor Name:University Hospitals Leuven (UZ Leuven)
    Full Title: The effect of corticotropin release hormone on duodenal markers and gastric sensorimotor function in healthy volunteers
    Medical condition: To assess the effect of the CRH on duodenal mast cell count, eosinophil count, immune activation, mucosal permeability and gastric sensorimotor function and gastrointestinal symptoms.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-004943-35 Sponsor Protocol Number: 5122016 Start Date*: 2017-03-01
    Sponsor Name:Radboud University Medical Center
    Full Title: Stimulation of ADH independent urine concentration in healthy volunteers
    Medical condition: healthy volunteers; the information of this pilot study will be used in the care of patients with diabetes insipidus
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-001265-17 Sponsor Protocol Number: 3.0 Start Date*: 2018-08-07
    Sponsor Name:Turku University Central Hospital
    Full Title: Relationship of edoxaban plasma concentration and blood coagulation in healthy volunteers using standard laboratory tests and viscoelastic analysis (EdoRot).
    Medical condition: Healthy volunteers
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: FI (Completed)
    Trial results: View results
    EudraCT Number: 2016-002519-17 Sponsor Protocol Number: DDD16JRtac Start Date*: 2016-09-12
    Sponsor Name:KU Leuven - Drug Delivery and Disposition
    Full Title: Supersaturation and precipitation of tacrolimus in the stomach of healthy volunteers
    Medical condition: Healthy human volunteers , investigation of the drug's supersaturation behaviour in the stomach
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2016-002700-78 Sponsor Protocol Number: DDD16RITONAVIR Start Date*: 2016-10-28
    Sponsor Name:KU Leuven - Drug Delivery and Disposition
    Full Title: Supersaturation and precipitation of ritonavir in the gastrointestinal tract of healthy volunteers
    Medical condition: Healthy human volunteers
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2019-003728-19 Sponsor Protocol Number: DDD19IBDMES2 Start Date*: 2021-01-27
    Sponsor Name:KU Leuven
    Full Title: Intestinal disposition of mesalazine in healthy volunteers
    Medical condition: Healthy volunteers
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2019-003271-19 Sponsor Protocol Number: DDD19IBDBUD Start Date*: 2019-12-20
    Sponsor Name:KU Leuven
    Full Title: Intestinal disposition of budesonide in healthy volunteers
    Medical condition: Healthy volunteers
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2014-002501-38 Sponsor Protocol Number: LY-OCCL-PRESSURE-1 Start Date*: 2015-07-08
    Sponsor Name:ULB - Unité de Recherche en Lymphologie
    Full Title: The occlusion pressure of superficial lymphatics in the upper extremity of healthy volunteers: A Near infrared lymphofluoroscopy approach
    Medical condition: lymphatic pressure in upper limb from healthy volunteers
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-004698-34 Sponsor Protocol Number: ScDex_v1.0 Start Date*: 2016-01-26
    Sponsor Name:University Of Turku
    Full Title: Pharmacokinetics of subcutaneously given dexmedetomidine in healthy volunteers
    Medical condition: healthy volunteers are studied.
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: FI (Completed)
    Trial results: View results
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    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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