Flag of the European Union EU Clinical Trials Register Help

Clinical trials for Helium

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
    How to search [pdf]
    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
    Advanced Search: Search tools
     
    25 result(s) found for: Helium. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2007-006233-14 Sponsor Protocol Number: 2007-006233-14 Start Date*: 2008-01-03
    Sponsor Name:Academic Medical Center
    Full Title: Organ protection by noble gases – Helium induced Early and Late Preconditioning (HELP) in human endothelium
    Medical condition: healthy volunteers helium induced organ protection
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-004158-10 Sponsor Protocol Number: ALMED-07-C2-012 Start Date*: 2008-04-17
    Sponsor Name:AIR LIQUIDE
    Full Title: A single site, exploratory, phase I / II, randomised trial comparing the effect of Helium/Oxygen mixtures (He/O2 78:22 and He/O2 65:35) to medical air on pulmonary function in moderate / severe ast...
    Medical condition: - healthy volunteers, - moderate and severe persistent asthmatic patients, - moderate and severe COPD patients
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-005289-37 Sponsor Protocol Number: 3_1_6 Start Date*: 2007-05-16
    Sponsor Name:University Witten/Herdecke
    Full Title: Anwendung von HELIOX an einem Modell der oberen Atemwegsobstruktion
    Medical condition: A model of upper airway obstruction will be used to test the hypothesis that HELIOX 21 when additional oxygen is added (which is a common clinical situation) still can reduce the work of breathing....
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-000992-12 Sponsor Protocol Number: HIPP-CABG Start Date*: 2008-03-27
    Sponsor Name:Academic Medical Center
    Full Title: Organ protection by noble gases – A clinical study to investigate Helium induced Pre- and Postconditioning in patients undergoing coronary artery bypass surgery (HIPP-CABG).
    Medical condition: patients undergoing coronary artery bypass surgery, helium induced pre- and postconditioning
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-010078-39 Sponsor Protocol Number: HeLIX Start Date*: 2009-06-03
    Sponsor Name:Academic Medical Center
    Full Title: The effect of helium on the immune system ex vivo
    Medical condition: Healthy volunteers, Effects of helium on the immune system ex vivo
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-005678-61 Sponsor Protocol Number: ESNOD-01 Start Date*: 2006-02-22
    Sponsor Name:University Hospital Tuebingen
    Full Title: Entwicklung einer Untersuchungsmethode zur Bestimmung des NO-Transferfaktors der Lunge Evaluierung der Methode und Normwerterhebung an gesunden Probanden (Development of a new method for steady-sta...
    Medical condition: Lung function testing (NO- and CO Transferfactor) in healthy subjects
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-002585-11 Sponsor Protocol Number: AL001 Start Date*: 2005-10-10
    Sponsor Name:Imperial College
    Full Title: CPAP;Heliox Effects on Stability and Therapeutics
    Medical condition: Respiratory Distress requiring CPAP Examples: Bronchilitis, post-exturbation, Upper Airway Obstruction...
    Disease:
    Population Age: Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-017499-26 Sponsor Protocol Number: Heres Start Date*: 2010-03-16
    Sponsor Name:Academical Medical Center, University of Amsterdam
    Full Title: The use of Helium after Resuscitation: a safety and feasibility study
    Medical condition: Persistent coma after cardiac arrest.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10038749 Resuscitation LLT
    12.1 10068191 Postresuscitation encephalopathy LLT
    12.1 10038749 Resuscitation PT
    12.1 10068191 Postresuscitation encephalopathy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-003612-30 Sponsor Protocol Number: 0904HELIOX Start Date*: 2005-11-23
    Sponsor Name:Barts and the London NHS Trust
    Full Title: A comparison of Helium-oxygen mixture (Heliox) with an oxygen-air mixture in reducing the work of breathing during weaning from mechanical ventilation.
    Medical condition: Patients admitted to the intensive care unit who are in the recovery phase of their illness and are weaning from mechanical ventilation.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-006173-33 Sponsor Protocol Number: ALMED-07-C3-009 Start Date*: 2009-10-09
    Sponsor Name:Air Liquide
    Full Title: An international phase III randomised trial comparing in severe Exacerbations of Chronic obstructive pulmonary disease the efficacy of Helium/Oxygen versus Air/Oxygen administered during spontaneo...
    Medical condition: Patients eligible for this study are critically ill patients with COPD admitted in ICU for an exacerbation of their chronic disease with hypercapnic acute respiratory failure.
    Disease: Version SOC Term Classification Code Term Level
    12.0 10009033 Chronic obstructive pulmonary disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) BE (Prematurely Ended) DE (Completed) IT (Ongoing) GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-000053-62 Sponsor Protocol Number: sph/itu/0001 Start Date*: 2007-06-18
    Sponsor Name:Ashford & St. Peter's Hospitals NHS Trust
    Full Title: The effects of helium-oxygen gas mixture (Heliox) on airway pressures in mechanically ventilated adult patients with acute lung injury
    Medical condition: Acute lung injury
    Disease: Version SOC Term Classification Code Term Level
    9.1 10038696 Respiratory failure (excl neonatal) LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2005-003007-36 Sponsor Protocol Number: HP002A Start Date*: 2006-08-02
    Sponsor Name:Imperial College London [...]
    1. Imperial College London
    2. BOC Ltd.
    Full Title: B.R.E.A.T.H.E. Bronchiolitis RCT: Emergency Assisted Therapy with Heliox - an Evaluation. A Prospective, Double-Blinded, Randomised, Controlled Clinical Trial to assess the effect of helium-oxygen ...
    Medical condition: Bronchiolitis
    Disease: Version SOC Term Classification Code Term Level
    8.1 10006448 Bronchiolitis LLT
    Population Age: Preterm newborn infants, Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2013-004837-34 Sponsor Protocol Number: STH17245 Start Date*: 2014-08-20
    Sponsor Name:Sheffield Teaching Hospitals NHS Foundation Trust
    Full Title: Lung HeXeRT: Advanced proton, hyperpolarised 3helium and 129xenon magnetic resonance imaging for lung cancer radiotherapy planning and evaluation
    Medical condition: Lung Cancer
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10061873 Non-small cell lung cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-007775-17 Sponsor Protocol Number: ALMED-07-C2-017 Start Date*: 2009-10-14
    Sponsor Name:Air Liquide
    Full Title: A single centre, exploratory, phase II, cross-over, randomised trial, evaluating the effect of spontaneously breathing Helium/Oxygen (65%/35%), to either spontaneously breating Nitrogen/Oxygen (65%...
    Medical condition: Severe chronic obstructive pneumonary disease (COPD) patients during a Six-Minute Walking Test
    Disease: Version SOC Term Classification Code Term Level
    12.0 10009033 Chronic obstructive pulmonary disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-000832-42 Sponsor Protocol Number: n/a Start Date*: 2008-11-05
    Sponsor Name:East Kent Hospital Trust
    Full Title: Effectiveness of Heliox in Hypercapnic Respiratory Failure
    Medical condition: Hypercapnic Respiratory Failure due to excerbation of Chronic Obstructive Pulmonary Disease
    Disease: Version SOC Term Classification Code Term Level
    9.1 10010953 COPD exacerbation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-017014-80 Sponsor Protocol Number: Helium_and_the_coronary_circulation Start Date*: 2010-02-22
    Sponsor Name:Academical Medical Center, University of Amsterdam
    Full Title: The effect of helium inhalation on the coronary circulation and vessel diameter
    Medical condition: Coronary artery disease
    Disease: Version SOC Term Classification Code Term Level
    12.0 10011078 Coronary artery disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2010-022393-13 Sponsor Protocol Number: Helium-MI Start Date*: 2010-11-24
    Sponsor Name:Academical Medical Center, University of Amsterdam
    Full Title: Does helium protect the heart against ischaemia-reperfusion damage in patients with acute myocardial infarction?
    Medical condition: Acute myocardial infarction
    Disease: Version SOC Term Classification Code Term Level
    12.1 10000891 Acute myocardial infarction LLT
    12.1 10051624 Myocardial reperfusion injury LLT
    12.1 10063837 Reperfusion injury LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-004851-12 Sponsor Protocol Number: 06/Q0504/33 Start Date*: 2008-01-03
    Sponsor Name:Whittington Hospital NHS Trust
    Full Title: Prospective randomised cross over comparison on the physiological response to non-invasive ventilation using either Air O2 or Heliox21
    Medical condition: Respiratory failure
    Disease: Version SOC Term Classification Code Term Level
    9.1 10038695 Respiratory failure PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2009-009599-11 Sponsor Protocol Number: 08/0339 Start Date*: 2011-02-15
    Sponsor Name:Joint UCLH/UCL/Royal Free Biomedical Research Unit
    Full Title: Prospective randomised cross over comparison on the physiological response to non-invasive ventilation using either Air O2 or Heliox21
    Medical condition: Respiratory failure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-008274-31 Sponsor Protocol Number: ARKFTN-1/2008 Start Date*: 2009-06-12
    Sponsor Name:Fakultní Thomayerova nemocnice s poliklinikou
    Full Title: Establishing a new method of heliox administration in the management of acute exacerbation of chronic obstructive lung disease
    Medical condition: Těžká exacerbace chronické obstrukční plicní nemoci
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: (No results available)
    Download Options:
    Number of Trials to download:
    Download Content:
    Download Format:
    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
    1  2  Next»
    Query did not match any studies.
    For support, Contact us.
    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

    European Medicines Agency © 1995-Wed May 14 06:51:31 CEST 2025 | Domenico Scarlattilaan 6, 1083 HS Amsterdam, The Netherlands
    EMA HMA