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Clinical trials for Hypertension

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   43865   clinical trials with a EudraCT protocol, of which   7286   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    1,712 result(s) found for: Hypertension. Displaying page 1 of 86.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2007-000310-36 Sponsor Protocol Number: 2542 Start Date*: 2007-04-05
    Sponsor Name:Radboud University Medical Center Njmegen
    Full Title: Does statin therapy reduce sympathoexcitation in hypertension
    Medical condition: hypertension and sympathoexcitation
    Disease: Version SOC Term Classification Code Term Level
    9.1 10020782 Hypertension NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2009-017831-16 Sponsor Protocol Number: 26169 Start Date*: 2010-07-15
    Sponsor Name:Institute of pharmacology, Aarhus university
    Full Title: Effects of 6 months intensive vasodilating treatment on vascular resistance and coronary flow reserve in hypertensive patients
    Medical condition: Essential Hypertension and changes in the vasculature related to high blood pressure.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10015488 Essential hypertension LLT
    12.1 10015489 Essential hypertension, benign LLT
    12.1 10015491 Essential hypertension, unspecified LLT
    12.1 10020772 Hypertension LLT
    12.1 10020775 Hypertension arterial LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-014534-15 Sponsor Protocol Number: NACIPP Start Date*: 2009-10-01
    Sponsor Name:AZIENDA SANITARIA OSPEDALIERA "S. GIOVANNI BATTISTA DI TORINO"
    Full Title: EFFECT OF ACUTE ADMINISTRATION OF N-ACETYLCYSTEINE ON BLOOD PRESSURE OF PULMONARY ARTERIAL IN PRIMARY PULMONARY HYPERTENSION.
    Medical condition: PRIMARY PULMONARY HYPERTENSION
    Disease: Version SOC Term Classification Code Term Level
    9.1 10036727 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-000077-22 Sponsor Protocol Number: CL2-90652-001 Start Date*: Information not available in EudraCT
    Sponsor Name:Institut de Recherches Internationales Servier
    Full Title: Acceptability, safety, pharmacokinetics and effects on blood pressure of a daily dose of 0.025 to 0.135 milligram per kilogram of S 90652, a paediatric formulation of perindopril, in 2-16 years old...
    Medical condition: Arterial hypertension
    Disease: Version SOC Term Classification Code Term Level
    5.1 10020782 PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: BE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2013-003144-23 Sponsor Protocol Number: PANDA Start Date*: 2014-02-03
    Sponsor Name:King's College London [...]
    1. King's College London
    2. Guy's and St Thomas' NHS Foundation Trust
    Full Title: Pregnancy And chronic hypertension: NifeDipine or labetalol as Antihypertensive treatment
    Medical condition: Chronic hypertension in pregnancy
    Disease: Version SOC Term Classification Code Term Level
    16.1 10047065 - Vascular disorders 10036695 Primary hypertension LLT
    16.1 10047065 - Vascular disorders 10039834 Secondary hypertension PT
    16.1 10047065 - Vascular disorders 10015488 Essential hypertension PT
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2004-003955-37 Sponsor Protocol Number: CL3-05590-022 Start Date*: 2005-03-29
    Sponsor Name:INSTITUT DE RECHERCHES INTERNATIONALES SERVIER
    Full Title: Efficacy of perindopril/indapamide combination on coronary Pet Scan parameters. A 6 month, open non controlled stydy in hypertensive patients
    Medical condition: Essential arterial hypertension
    Disease: Version SOC Term Classification Code Term Level
    6.1 10015488 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2004-003847-37 Sponsor Protocol Number: REM 04 15 Start Date*: 2004-12-21
    Sponsor Name:BIOPROJET
    Full Title: An Open label uncontrolled study of the safety and efficacy of chronic intravenous Remodulin in patients with pulmonary Arterial Hypertension
    Medical condition: Pulmonary Arterial Hypertension
    Disease: Version SOC Term Classification Code Term Level
    6.1 10037400 PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2011-004411-22 Sponsor Protocol Number: CSPP100A2365E2 Start Date*: 2012-03-14
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A multicenter, 52 to 104 week extension study to evaluate the long term growth and development of pediatric hypertensive patients 6 – 17 years of age treated previously with aliskiren
    Medical condition: Hypertension
    Disease: Version SOC Term Classification Code Term Level
    14.1 10047065 - Vascular disorders 10020772 Hypertension PT
    14.1 10047065 - Vascular disorders 10039834 Secondary hypertension PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA SK (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2016-000347-14 Sponsor Protocol Number: PROCLAIM Start Date*: 2016-06-16
    Sponsor Name:IDIBAPS
    Full Title: Cell proliferation in pulmonary hypertension: mollecular imaging detection by FDG PET. Comparative study between patients and healthy subjects
    Medical condition: Pulmonary artery hypertension and thromboembolic chronic pulmonary hypertension
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004855 10037405 Pulmonary hypertension primary LLT
    19.0 100000004855 10068739 Chronic thromboembolic pulmonary hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-000194-21 Sponsor Protocol Number: 150/04 Start Date*: 2004-12-31
    Sponsor Name:AZIENDA OSPEDALIERA POLICLINICO DI MODENA
    Full Title: Effetti della L-argina nella profilassi della ipertensione cronica dal secondo trimestre di gravidanza
    Medical condition: Profilassi della ipertensione cronica dal secondo trimestre di gravidanza
    Disease: Version SOC Term Classification Code Term Level
    9.1 10036563 Pregnancy induced hypertension LLT
    Population Age: Adults Gender: Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-001893-24 Sponsor Protocol Number: Bay63-2521/14986 Start Date*: 2011-10-13
    Sponsor Name:Bayer HealthCare AG
    Full Title: Relative bioavailability and food effect study of two oral liquid formulations in comparison to a 1mg tablet of riociguat to characterize its pharmacokinetic properties in healthy male and female a...
    Medical condition: Children with PH due to • Pulmonary arterial hypertension (PAH) • persistent pulmonary hypertension of the newborn (PPHN)
    Disease: Version SOC Term Classification Code Term Level
    14.0 10038738 - Respiratory, thoracic and mediastinal disorders 10037405 Pulmonary hypertension primary LLT
    14.0 10038738 - Respiratory, thoracic and mediastinal disorders 10036727 Primary pulmonary hypertension LLT
    14.0 10010331 - Congenital, familial and genetic disorders 10053592 Newborn persistent pulmonary hypertension LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-004938-16 Sponsor Protocol Number: 00-MEP-04 Start Date*: 2008-02-19
    Sponsor Name:Astellas Pharma Europe B.V.
    Full Title: A RANDOMISED, DOUBLE-BLIND STUDY TO COMPARE THE EFFECT ON SYMPATHETIC ACTIVITY AND HEMODYNAMIC PROFILE OF BARNIDIPINE AND AMLODIPINE IN PATIENTS WITH MILD TO MODERATE ESSENTIAL HYPERTENSION.
    Medical condition: Mild to moderate hypertension
    Disease: Version SOC Term Classification Code Term Level
    9.1 10015488 Essential hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-000690-34 Sponsor Protocol Number: 0954A-327 Start Date*: 2007-05-29
    Sponsor Name:Merck Sharp & Dohme OÜ
    Full Title: A Randomized, Double-Blind, Active Comparator Study to Evaluate the Antihypertensive Efficacy and Safety of Losartan/HCTZ Combination as Compared to Losartan Monotherapy in Pediatric Patients With ...
    Medical condition: Essential Hypertension
    Disease: Version SOC Term Classification Code Term Level
    9.1 10015488 Essential hypertension LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: EE (Prematurely Ended) FI (Prematurely Ended) LT (Prematurely Ended) HU (Completed) DE (Completed) GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-016738-28 Sponsor Protocol Number: ALISEI Start Date*: 2009-12-11
    Sponsor Name:AZIENDA OSPEDALIERA PISANA
    Full Title: Phase IV prospective, randomized, open with blind endpoints, parallel group study to evaluate the effect of Aliskiren on endothelial dysfunction in patients with essential hypertension
    Medical condition: essential hypertension
    Disease: Version SOC Term Classification Code Term Level
    12.0 10015488 Essential hypertension LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-000631-25 Sponsor Protocol Number: 2007-000631-25 Start Date*: 2010-06-08
    Sponsor Name:KAROLINSKA INSTITUTET
    Full Title: THE ANTITTHROMBOTIC EFFECTS OF DOXAZOSIN AND RAMIPRIL IN ESSENTIAL HYPERTENSION
    Medical condition: ESSENTIAL HYPERTENSION
    Disease: Version SOC Term Classification Code Term Level
    12.1 10015488 Essential hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-001001-41 Sponsor Protocol Number: PR002-CLN-pro008 Start Date*: 2008-06-02
    Sponsor Name:Protherics Medicines Development Ltd, a BTG plc company
    Full Title: A Randomized, Double Blind, Placebo Controlled Study of the Efficacy and Safety of Angiotensin Therapeutic Vaccine (ATV) in Patients With Mild to Moderate Hypertension
    Medical condition: Men and women, 35-70 years old with mild to moderate Hypertension as classified by the British Hypertension Society (BHS) Guidelines - BHS-IV based on the following crietia of sitting blood pressur...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10020772 Hypertension LLT
    9.1 10020772 Hypertension PT
    9.1 10042957 Systolic hypertension PT
    9.1 10012758 Diastolic hypertension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-002422-29 Sponsor Protocol Number: 1235.8 Start Date*: 2007-10-19
    Sponsor Name:Boehringer Ingelheim Ltd.
    Full Title: An open-label follow-up trial of the efficacy and safety of chronic administration of the combination of telmisartan 40mg + amlodipine 10mg or the combination of telmisartan 80mg + amlodipine 10mg ...
    Medical condition: essential hypertension
    Disease: Version SOC Term Classification Code Term Level
    9.1 10015488 Essential hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Completed) GB (Completed) AT (Completed) CZ (Completed) ES (Completed) IT (Completed) BG (Completed) SK (Completed)
    Trial results: View results
    EudraCT Number: 2009-017155-10 Sponsor Protocol Number: 10-aifa-2005-01 Start Date*: 2006-11-07
    Sponsor Name:CASA DI CURA PRIVATA S.RAFFAELE - PISANA
    Full Title: Evaluation of tolerability and efficacy of the combination Sildenafil/Bosentan in patients with severe pulmonary hypertension.
    Medical condition: severe pulmonary hypertension
    Disease: Version SOC Term Classification Code Term Level
    14.0 10038738 - Respiratory, thoracic and mediastinal disorders 10037401 Pulmonary hypertensions HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-011156-21 Sponsor Protocol Number: CCFM 119/209 Start Date*: 2011-04-28
    Sponsor Name:FONDAZIONE MONZINO CENTRO CARDIOLOGICO
    Full Title: Effects of beta-blockers on exercise performance in uncomplicated hypertension
    Medical condition: Non complicated arterial hypertension
    Disease: Version SOC Term Classification Code Term Level
    14.0 10047065 - Vascular disorders 10015488 Essential hypertension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-004224-37 Sponsor Protocol Number: EREMIT Start Date*: Information not available in EudraCT
    Sponsor Name:Universität Leipzig
    Full Title: Everolimus in der Therapie von Patienten mit pulmonaler Hypertonie
    Medical condition: - steady or progressive pulmonary hypertension accompanied by at least two of the following parameters associated with a poor prognosis: - Cardiac index ≤ 2,1 l/min/m2 - 6 MWD ≤ 380 m - systolic RR...
    Disease: Version SOC Term Classification Code Term Level
    8.1 10037400 Pulmonary hypertension PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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