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Clinical trials for Ibuprofen

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    160 result(s) found for: Ibuprofen. Displaying page 1 of 8.
    1  2  3  4  5  6  7  8  Next»
    EudraCT Number: 2016-002119-16 Sponsor Protocol Number: NORM2016-IQ Start Date*: 2016-11-10
    Sponsor Name:Aflofarm Farmacja Polska Sp. z o.o.
    Full Title: Multi-center phase 3 clinical study of fever reduction effectiveness in children age 24-72 months using combined therapy (ibuprofen plus paracetamol) compared to monotherapy with paracetamol and/or...
    Medical condition: Fever due to viral infection
    Disease: Version SOC Term Classification Code Term Level
    20.1 10021881 - Infections and infestations 10051998 Febrile infection PT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: PL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-006846-24 Sponsor Protocol Number: HTA074801 Start Date*: 2009-02-27
    Sponsor Name:North West London Hospitals NHS Trust
    Full Title: An Evaluation of the Effectiveness of Ibuprofen and Morphine for Acute Pain in Sickle Cell Disease
    Medical condition: Sickle Cell Disease
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2015-002446-31 Sponsor Protocol Number: FMLD-HUNGRIA-28_FIII Start Date*: 2017-03-08
    Sponsor Name:LABORATORIOS FARMALIDER S.A.
    Full Title: Phase III clinical trial , multicenter , randomized , double-blind , crossover, active-controlled and placebo to evaluate the analgesic efficacy and safety of paracetamol / ibuprofen 500/200 mg com...
    Medical condition: MODERATE TO SEVERE PAIN FOLLOWING DYSMENORRHOEA
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-000736-25 Sponsor Protocol Number: IB3M.2019 Start Date*: 2019-09-05
    Sponsor Name:Universidad Complutense de Madrid
    Full Title: Efficacy of Non-Steroidal Anti-Inflammatory (Ibuprofen) Chronotherapy in Healing After Mandibular Third Molar Surgical Extraction – A Randomized Clinical Trial
    Medical condition: The clinical trial will try to understand if the elimination of the ibuprofen dosage in resting phase after surgical third molar extraction not jeopardize the postoperative period .
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-006762-29 Sponsor Protocol Number: NL0804 Start Date*: 2009-01-16
    Sponsor Name:Reckitt Benckiser Healthcare (UK) Ltd
    Full Title: A double-blind, randomised, crossover, single dose, single centre, study examining the analgesic efficacy and tolerability of fixed-dose combinations of ibuprofen 200mg and acetaminophen 500mg, ibu...
    Medical condition: Primary Dysmenorrhoea
    Disease: Version SOC Term Classification Code Term Level
    9.1 10036689 Primary dysmenorrhoea LLT
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2019-000242-35 Sponsor Protocol Number: 18CT0003 Start Date*: Information not available in EudraCT
    Sponsor Name:E-Pharma Trento SpA
    Full Title: Randomized, double blind, double dummy, parallel-groups, clinical trial on efficacy and safety of ibuprofen/N-acetylcysteine fixed dose combination vs. individual components (ibuprofen and N-acetyl...
    Medical condition: symptomatic non-complicated upper respiratory tract infections
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004862 10046309 Upper respiratory tract infections HLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2013-001442-34 Sponsor Protocol Number: IBUPAI0002 Start Date*: 2013-08-06
    Sponsor Name:McNeil AB
    Full Title: A SINGLE-DOSE, RANDOMIZED, TWO-PERIOD, CROSSOVER STUDY TO ASSESS BIOEQUIVALENCE BETWEEN TWO IBUPROFEN 200 MG TABLET FORMULATIONS, IN HEALTHY ADULTS.
    Medical condition: Pain
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2004-002137-39 Sponsor Protocol Number: V1 25/07/04 Start Date*: 2004-09-17
    Sponsor Name:
    Full Title: A randomised controlled trial of the combined use of paracetamol and ibuprofen to treat febrile children
    Medical condition: Fevers in childhood not asscoaited with severe disease in the immunocompenetent or fever in the immunocompromised host.
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2004-004267-30 Sponsor Protocol Number: Gebro-III-21-10 Start Date*: 2005-02-21
    Sponsor Name:Gebro Pharma GmbH
    Full Title: Efficacy and Tolerability of Dexibuprofen Film coated tablets in Comparison to Ibuprofen in Children and Adolescents with Tonsillopharyngitis
    Medical condition: Tonsillopharyngitis
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2019-002779-32 Sponsor Protocol Number: PREEMTIVE Start Date*: 2019-12-26
    Sponsor Name:BERTA CASTELLANO PAULIS
    Full Title: “Pre-emptive analgesia with Ibuprofen in outpatient laparoscopic cholecystectomy. Recovery Quality ”
    Medical condition: AMBULATORY LAPAROSCOPIC COLECISTECTOMY
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-001143-32 Sponsor Protocol Number: Algofrenelle-01 Start Date*: 2018-07-27
    Sponsor Name:Ioulia and Irene Tseti Pharmaceutical Laboratories S.A., d.t. "Intermed S.A."
    Full Title: Efficacy of a new ibuprofen formulation for vaginal application
    Medical condition: Analgesic and anti-inflammatory action after gynecological surgical procedures
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10053467 Antiinflammatory therapy PT
    20.0 10042613 - Surgical and medical procedures 10036276 Postoperative analgesia PT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: GR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-005240-33 Sponsor Protocol Number: MENTH001 Start Date*: 2016-02-26
    Sponsor Name:The Mentholatum Company Ltd
    Full Title: A single centre, randomised, single-blind, parallel group single dose study to compare the speed of onset of ibuprofen gel, ibuprofen gel with levomenthol, and diclofenac gel in the relief of pain ...
    Medical condition: Pain of strains, sprains and sports injuries
    Disease: Version SOC Term Classification Code Term Level
    18.1 10022117 - Injury, poisoning and procedural complications 10065016 Post-traumatic pain PT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2022-002436-31 Sponsor Protocol Number: ALGIPED Start Date*: 2023-05-16
    Sponsor Name:Dicofarm S.p.A.
    Full Title: Randomized, controlled, transversal phase IV study on the efficacy and speed of action of lysin ibuprofen vs ibuprofen on the treatment of acute pain in children (ALGIPED).
    Medical condition: Acute pain in pediatric age
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004867 10066714 Acute pain LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Not Authorised)
    Trial results: (No results available)
    EudraCT Number: 2015-004077-32 Sponsor Protocol Number: BCRU/11/Ibu-AOM/001 Start Date*: 2015-12-29
    Sponsor Name:Berlin-Chemie AG
    Full Title: A randomized open-label, multinational, multicentre, phase III clinical study to evaluate the efficacy and safety of Ibuprofen oral suspension 20 mg/ml and Ibuprofen oral suspension 40 mg/ml (Berli...
    Medical condition: Acute otitis media (AOM) is an acute inflammatory disease involving the mucosa of the middle ear. AOM is one of the most frequent complications of upper respiratory tract infections in children. T...
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2014-004176-35 Sponsor Protocol Number: AH-09-10 Start Date*: 2015-06-26
    Sponsor Name:Pfizer
    Full Title: Evaluation Of The Efficacy Of A Novel Ibuprofen Formulation In The Treatment Of Post Surgical Dental Pain: Study I
    Medical condition: Post Surgical Dental Pain
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2010-018771-23 Sponsor Protocol Number: 2010-0128771-23 Start Date*: 2010-03-03
    Sponsor Name:AZIENDA OSPEDALIERA "S. CROCE E CARLE"
    Full Title: Therapy of patency of ductus arteriosus (PDA) in very low birth weight (VLBW)preterm infants: oral ibuprofen versus intravenous ibuprofen
    Medical condition: treatment on pharmacological closure of patent ductus arteriosus (PDA)in preterm very low birthweight infants.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10028920 HLGT
    Population Age: Preterm newborn infants, Under 18 Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-003177-14 Sponsor Protocol Number: IBUPAR-Trial Start Date*: 2016-04-06
    Sponsor Name:
    Full Title: Paracetamol versus ibuprofen in preterm infants with a hemodynamically significant patent ductus arteriosus: a randomized clinical trial.
    Medical condition: Persistent ductus arteriosus haemodynamically significant
    Disease:
    Population Age: Preterm newborn infants, Under 18 Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-002776-14 Sponsor Protocol Number: 97 Start Date*: 2013-03-15
    Sponsor Name:University of Oslo, Faculty of medicine, Institute of Health and Society
    Full Title: Ibuprofen versus mecillinam for uncomplicated cystitis in adult, non-pregnant women
    Medical condition: Uncomplicated cystitis in adult, non pregnant women, age 18-60.
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004862 10000699 Acute cystitis (excl in pregnancy) LLT
    Population Age: Adults Gender: Female
    Trial protocol: NO (Completed) DK (Completed) SE (Completed)
    Trial results: View results
    EudraCT Number: 2018-000138-37 Sponsor Protocol Number: FMLD-HUNGRIA-2-42_FIII Start Date*: 2018-04-25
    Sponsor Name:Laboratorios Farmalíder S.A.
    Full Title: PHASE III CLINICAL TRIAL FOR THE EVALUATION OF THE EFFICACY AND SAFETY OF A PARACETAMOL + IBUPROFEN COMBINATION IN PATIENTS WITH PRIMARY DYSMENORRHOEA
    Medical condition: DYSMENORRHOEA
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-003790-41 Sponsor Protocol Number: JAN12006-01 Start Date*: 2015-05-11
    Sponsor Name:Spherium Biomed
    Full Title: Randomised, double-blinded, placebo and active comparator controlled exploratory clinical trial to assess the efficacy and safety of a triple combination of Ibuprofen, magnesium and ascorbic acid ...
    Medical condition: Temporomandibular joint dysfunction syndrome.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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