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Clinical trials for Immunosuppression

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    294 result(s) found for: Immunosuppression. Displaying page 1 of 15.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2006-005774-50 Sponsor Protocol Number: 9834p Start Date*: 2007-05-18
    Sponsor Name:Central Manchester & Manchester Children's University Hospitals NHS Trust
    Full Title: Protocol for taking pharmacogenetic testing of tacrolimus into the clinical arena: patient tailored anti-rejection therapy
    Medical condition: The study is to determine whether MDR-1 genotyping correlates with tacrolimus dose in individual patients and could therefore be used in future to predict tacrolimus dose. All patients will have u...
    Disease: Version SOC Term Classification Code Term Level
    8.1 10021510 Immunosuppression NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-003604-21 Sponsor Protocol Number: KT-IBA Start Date*: 2011-10-24
    Sponsor Name:Universitätsklinik für Innere Medizin IV, Medizinische Universität Innsbruck
    Full Title: The role of immunosuppressives in immunosenescence and immunotolerance in renal transplantation
    Medical condition: The impact of immunosuppressives on age-related changes of the immune system will be analyzed in patients after renal transplantation. Only patients at least one year after renal tranplantation and...
    Disease: Version SOC Term Classification Code Term Level
    14.0 10021428 - Immune system disorders 10062016 Immunosuppression PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2012-001352-19 Sponsor Protocol Number: 20120309-01 Start Date*: 2012-10-15
    Sponsor Name:Medizinische Hochschule Hannover
    Full Title: BE-RELACs-Trial: Biomarkers Explaining RELevance of ACute Rejections
    Medical condition: Kidney transplantation
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021428 - Immune system disorders 10062016 Immunosuppression PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-017192-26 Sponsor Protocol Number: BUILT_01 Start Date*: 2012-06-21
    Sponsor Name:Free State of Bavaria represented by Regensburg University represented by Regensburg University Hospital represented by
    Full Title: A 3-Armed Prospective Randomized Controlled, Open-Labeled Phase III Trial to Evaluate Late Introduction of Cyclosporine or Everolimus versus a 5-day Delay of Cyclosporine in Combination with MMF in...
    Medical condition: Liver transplantation, renal function, high MELD scores, infections, "bottom-up" immunosuppression
    Disease: Version SOC Term Classification Code Term Level
    16.1 10021428 - Immune system disorders 10062016 Immunosuppression PT
    16.1 100000004857 10021523 Impaired renal function LLT
    16.1 100000004865 10024716 Liver transplantation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2014-003119-13 Sponsor Protocol Number: 14/0172 Start Date*: 2015-02-11
    Sponsor Name:Joint Research Office- UCL
    Full Title: Can simvastatin significantly reduce the amount of immunosuppressive medication required by patients with sight threatening uveitis? A phase IIb, single site, randomized, placebo controlled, double...
    Medical condition: Uveitis
    Disease: Version SOC Term Classification Code Term Level
    19.1 10021428 - Immune system disorders 10062016 Immunosuppression PT
    19.1 10015919 - Eye disorders 10046851 Uveitis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-019398-14 Sponsor Protocol Number: RB02 Start Date*: 2010-10-07
    Sponsor Name:Erasmus Medical Center
    Full Title: IMPROVEMENT OF RENAL FUNCTION BY CONVERSION OF TACROLIMUS TO EVEROLIMUS 3 MONTHS AFTER KIDNEY TRANSPLANTATION
    Medical condition: Kidney Transplantation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-000633-39 Sponsor Protocol Number: FEC-TH Start Date*: 2012-05-21
    Sponsor Name:Fundación para la Formación e Investigación Sanitaria
    Full Title: Extracorporeal photopheresis in liver transplantation. Clinical trial phase I/II safety and efficacy in patients with progressive withdrawal of immunosuppression.
    Medical condition: Liver transplantation more than 2 years of evolution to complications of immunosuppression.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-003198-17 Sponsor Protocol Number: UZB_20160728 Start Date*: 2016-09-29
    Sponsor Name:Universitair Ziekenhuis Brussel Vrije Universiteit Brussel
    Full Title: A Prospective Interventional Pilot Study on the Use of Valproic Acid for Treatment of Idiopathic Nephrotic Syndrome
    Medical condition: Treatment of Idiopathic Nephrotic Syndrome
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-003561-40 Sponsor Protocol Number: PATRON_07 Start Date*: 2008-06-10
    Sponsor Name:Regensburg University Medical Center, Department of Surgery
    Full Title: A Pilot Study to Determine the Safety and Efficacy of Induction-Therapy, De Novo MPA and Delayed mTOR-Inhibition in Liver Transplant Recipients with Impaired Renal Function - PATRON-Study
    Medical condition: Evaluation of the safety and efficacy of CNI-free immunosuppressive treatment of patients undergoing liver transplantation with a preexisting renal impairment.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10062237 Renal impairment LLT
    9.1 10024716 Liver transplantation LLT
    9.1 10062016 Immunosuppression LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-005635-10 Sponsor Protocol Number: ATEGE_LIVER Start Date*: 2006-05-22
    Sponsor Name:Liver Unit, ICMD, Hospital Clinic Barcelona
    Full Title: INDUCTION TREATMENT FOLLOWED BY IMMUNOSUPPRESSION WITHDRAWAL IN LIVER TRANSPLANTATION: A COMPARATIVE TRIAL. Tratamiento de inducción y retirada de la inmunosupresión en el trasplante hepático. Estu...
    Medical condition: Liver transplantation
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-012712-40 Sponsor Protocol Number: ISINODAT 1/09 Start Date*: 2009-07-30
    Sponsor Name:Medizinische Universität Wien, Univ.Klinik Innere Medizin III, Abt.für Nephrologie u.Dialyse
    Full Title: Improving Secretion of Insulin in New Onset Diabetes after Renal Transplantation (ISINODAT)
    Medical condition: New onset diabetes mellitus after renal transplantation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2007-002125-68 Sponsor Protocol Number: IM103-045 Start Date*: 2007-11-23
    Sponsor Name:Bristol-Myers Squibb International Corporation
    Full Title: Evaluation of Belatacept as First-line Immunosuppression in De Novo Liver Transplant Recipients Revised Protocol Number 04, incorporating Amendments 02, 03, 04 and 05 (version 10.0 dated 20-Nov-0...
    Medical condition: First time recipient of a deceased donor liver transplant
    Disease: Version SOC Term Classification Code Term Level
    9.1 10024714 Liver transplant LLT
    9.1 10062016 Immunosuppression LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended) DE (Prematurely Ended) FR (Completed) ES (Prematurely Ended) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-000999-15 Sponsor Protocol Number: ONEmreg12 Start Date*: 2014-02-10
    Sponsor Name:University Hospital Regensburg
    Full Title: The ONE Study: A Unified Approach to Evaluating Cellular Immunotherapy in Solid Organ Transplantation - M reg Trial
    Medical condition: Kidney allograft rejection following living-donor renal transplantation.
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004863 10051366 Kidney graft dysfunction LLT
    17.0 100000004870 10049581 Graft rejection episode LLT
    17.0 100000004863 10069030 Graft failure LLT
    17.0 100000004865 10050436 Prophylaxis against renal transplant rejection LLT
    17.0 100000004870 10038297 Rejection acute renal LLT
    17.0 100000004870 10021510 Immunosuppression NOS LLT
    17.0 100000004863 10038299 Rejection chronic renal LLT
    17.0 100000004870 10066543 Acute allograft rejection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-001117-86 Sponsor Protocol Number: 16/0340 Start Date*: 2017-07-25
    Sponsor Name:University College London
    Full Title: A phase IV, prospective, randomised single-blind UK multicentre non-inferiority trial of low-dose versus standard dose rituximab for prevention of relapses in acquired TTP
    Medical condition: Acquired thrombotic thrombocytopenic purpura
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2017-000177-37 Sponsor Protocol Number: LITE Start Date*: 2017-09-21
    Sponsor Name:King's College London [...]
    1. King's College London
    2. King's College Hospital
    Full Title: Low-dose IL-2 to expand endogenous regulatory T cells and achieve tolerance in liver transplantation
    Medical condition: Discontinuation of immunosuppression in liver transplantation
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10024714 Liver transplant PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-002267-26 Sponsor Protocol Number: 13071981 Start Date*: 2012-04-12
    Sponsor Name:Medizinische Universität Wien
    Full Title: Hepatitis C in renal transplant recipients – Safety and efficacy of a conversion of immunosuppression to high-dose cyclosporine A and its impact on HCV-replication, parameters of liver function and...
    Medical condition: renal transplant recipients with hepatitis C
    Disease: Version SOC Term Classification Code Term Level
    14.1 10022891 - Investigations 10057394 Hepatitis C positive LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2011-004301-24 Sponsor Protocol Number: ONErgt11 Start Date*: 2012-01-05
    Sponsor Name:Free State of Bavaria, represented by the University of Regensburg, represented by Prof. Edward K. Geissler
    Full Title: The ONE Study: A Unified Approach to Evaluating Cellular Immunotherapy in Solid Organ Transplantation – Reference Group Trial
    Medical condition: Kidney allograft rejection following living-donor renal transplantation.
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004863 10051366 Kidney graft dysfunction LLT
    14.1 100000004870 10049581 Graft rejection episode LLT
    14.1 100000004865 10050436 Prophylaxis against renal transplant rejection LLT
    14.1 100000004863 10069030 Graft failure LLT
    14.1 100000004870 10038297 Rejection acute renal LLT
    14.1 100000004870 10021510 Immunosuppression NOS LLT
    14.1 100000004863 10038299 Rejection chronic renal LLT
    14.1 100000004870 10066543 Acute allograft rejection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) FR (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2017-004983-37 Sponsor Protocol Number: FFIS-INM-2017-04 Start Date*: 2018-10-16
    Sponsor Name:Fundación para la Formación e Investigación Sanitarias de la Región de Murcia
    Full Title: Multicenter, randomized, prospective study to establish the clinical efficacy and the mechanisms of tolerance following immunosuppression withdrawal in liver transplantation
    Medical condition: Hepatic transplant
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-010640-34 Sponsor Protocol Number: THYTOTRA Start Date*: 2009-08-13
    Sponsor Name:AZIENDA OSPEDALIERA POLICLINICO DI MODENA
    Full Title: INDUCTION OF DONOR-SPECIFIC TOLERANCE IN PATIENTS WITH LIVER TRANSPLANTATION WITH RECIPIENT PRE-TREATMENT WITH THYMOGLOBULINE AND MINIMAL POST-TRANSPLANT IMMUNOSUPPRESSION.
    Medical condition: Adult recipients of first liver transplantation
    Disease: Version SOC Term Classification Code Term Level
    9.1 10024715 Liver transplant rejection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2014-002643-18 Sponsor Protocol Number: REDUCE Start Date*: 2018-09-04
    Sponsor Name:Charité Universitätsmedizin Berlin
    Full Title: REDUCE - Multicenter, prospective, randomized study investigating the efficacy and safety of a reduced immunosuppressive therapy with tacrolimus once daily in comparison to standard triple immunosu...
    Medical condition: Immunosuppression after kidney transplantion in elderly patients ≥65 years of age
    Disease: Version SOC Term Classification Code Term Level
    20.1 10021428 - Immune system disorders 10062016 Immunosuppression PT
    20.0 10021428 - Immune system disorders 10054990 Immunodeficiency secondary to organ transplantation LLT
    20.0 100000004863 10074474 Transplantation complications HLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing) GB (GB - no longer in EU/EEA) AT (Prematurely Ended) ES (Prematurely Ended) DK (Prematurely Ended)
    Trial results: (No results available)
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