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Clinical trials for Impacted

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44344   clinical trials with a EudraCT protocol, of which   7373   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    54 result(s) found for: Impacted. Displaying page 1 of 3.
    1  2  3  Next»
    EudraCT Number: 2005-005478-66 Sponsor Protocol Number: PDY5808 Start Date*: 2006-02-09
    Sponsor Name:Sanofi-Synthelabo Recherche
    Full Title: Effect of a single oral 120 µg dose of SSR150106XB compared to placebo on the assessment of post dental surgical pain after extraction of an impacted or partially impacted third molar in 90 male an...
    Medical condition: Men and women who are to undergo elective surgery for extraction of at least one lower impacted or partially impacted third molar
    Disease: Version SOC Term Classification Code Term Level
    8.1 10059723 LLTn
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-000200-14 Sponsor Protocol Number: Start Date*: 2005-07-08
    Sponsor Name:North Bristol NHS Trust
    Full Title: A randomised, double-blinded comparison of the effectiveness of intravenously administered Ketoralac versus Dexamethasone in the treatment of pain following surgical removal of third molar teeth un...
    Medical condition: Pain experienced after the surgical removal of impacted third molars.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-015589-74 Sponsor Protocol Number: NYC-IBU-1 Start Date*: 2009-10-02
    Sponsor Name:Nycomed Sweden Holding 2 AB
    Full Title: A controlled, randomized, double-blind, cross-over study of the onset of analgesic effect of two formulations of ibuprofen for the treatment of pain after oral surgery.
    Medical condition: Pain
    Disease: Version SOC Term Classification Code Term Level
    12.0 10033371 Pain LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2006-000193-77 Sponsor Protocol Number: 05/Q1405/78 Start Date*: 2007-03-20
    Sponsor Name:The University of Manchester
    Full Title: Protective analgesia using bupivacaine and conventional release ibuprofen versus bupivacaine and sustained release ibuprofen for postoperative pain relief in patients undergoing third molar surgery...
    Medical condition: Pain following surgical removal of impacted lower wisdom tooth/ teeth.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-003258-21 Sponsor Protocol Number: PDC-01-0205 Start Date*: 2022-05-19
    Sponsor Name:Cessatech A/S
    Full Title: Analgesic Efficacy and Pharmacokinetic-pharmacodynamic Relationship of Intranasally Administered Sufentanil, Ketamine, and CT001 after Impacted Mandibular Third Molar Extraction
    Medical condition: Healthy male or female participants scheduled for surgical removal of an impacted mandibular third molar, where bone removal is judged to be needed.
    Disease: Version SOC Term Classification Code Term Level
    21.0 100000004865 10050327 Dental surgery NOS LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2009-011980-35 Sponsor Protocol Number: 09PUK/DCsc05 Start Date*: 2009-08-03
    Sponsor Name:IBSA Institut Biochimique SA
    Full Title: Multicentre, randomised, double-blind (double-dummy), active comparator-controlled, phase III study of the efficacy and safety of a single s.c. Diclofenac HPBCD 75mg/1ml injection as compared to a ...
    Medical condition: acute moderate-to-severe post-surgical pain from dental surgery (impacted 3rd molar extraction)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10044049 Dental pain and sensation disorders HLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: Removed from public view
    EudraCT Number: 2009-011663-37 Sponsor Protocol Number: 09PUK/DCsc04 Start Date*: 2009-07-28
    Sponsor Name:IBSA, Institut Biochimique SA
    Full Title: Multicentre, randomized, double-blind, active comparator-and placebo-controlled, parallel-group phase III clinical study for the evaluation of Diclofenac HPBCD 25, 50 mg/ml administered as a single...
    Medical condition: acute moderate-to-severe post-surgical pain from dental surgery (impacted 3rd molar extraction)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10044049 Dental pain and sensation disorders HLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: Removed from public view
    EudraCT Number: 2005-005575-14 Sponsor Protocol Number: R-01270-A015 Start Date*: 2006-08-08
    Sponsor Name:Baxter R&D Europe S.C.R.L
    Full Title: A randomized, double-blind, placebo-controlled, single-dose, parallel-group comparison of the analgesic efficacy, safety and local tolerability of intravenous paracetamol 1% solution Bioren (test),...
    Medical condition: Post-surgical dental pain after removal of one or more impacted 3rd mandibular molar(s), associated with moderate to severe pain.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2015-004152-22 Sponsor Protocol Number: DEX-TRA-06 Start Date*: 2016-03-01
    Sponsor Name:MENARINI RICERCHE S.p.A.
    Full Title: Analgesic efficacy of oral dexketoprofen trometamol/tramadol hydrochloride versus tramadol hydrochloride/paracetamol: a randomised, double-blind, placebo and active-controlled, parallel group study...
    Medical condition: moderate to severe acute pain after removal of impacted lower third molar
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004867 10066714 Acute pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) HU (Completed) ES (Completed) PL (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2014-004682-24 Sponsor Protocol Number: DC0071BB405 Start Date*: 2015-04-27
    Sponsor Name:Institut de Recherche Pierre Fabre - Centre de R&D Pierre Fabre
    Full Title: Efficacy of DC071 mouthwash (0,2 % chlorhexidine digluconate) in peri-surgical care for preventing alveolar osteitis after third molar extraction. Prospective, multicenter, randomised, double-blin...
    Medical condition: Prevention of alveolar osteitis after third molar extraction
    Disease: Version SOC Term Classification Code Term Level
    18.1 10021881 - Infections and infestations 10066995 Alveolar osteitis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: EE (Completed) LV (Completed) LT (Completed) FR (Completed) ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-003323-11 Sponsor Protocol Number: ITIBU001 Start Date*: 2014-10-01
    Sponsor Name:"Sapienza" University of Rome
    Full Title: RANDOMIZED CLINICAL TRIAL, PLACEBO-CONTROLLED, SPLIT-MOUTH, A DOUBLE-BLIND, FOR THE EVALUATION OF THE EFFECTIVENESS OF PREemptive ANALGESIA BY ADMINISTRATION OF IBUPROFEN 400MG, FOR THE CONTROL ...
    Medical condition: POST-OPERATIVE ACUTE PAIN (DAPO)
    Disease: Version SOC Term Classification Code Term Level
    17.1 10017947 - Gastrointestinal disorders 10031009 Oral pain PT
    17.1 10017947 - Gastrointestinal disorders 10030973 Oral discomfort PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-004790-10 Sponsor Protocol Number: A2720382 Start Date*: 2007-06-06
    Sponsor Name:GlaxoSmithKline Consumer Healthcare
    Full Title: A Proof-of-Principle Analgesic Adjuvant Pilot Study in Post-Operative Dental Pain
    Medical condition: Analgesia induced by dental extraction
    Disease: Version SOC Term Classification Code Term Level
    8.1 10044049 Dental pain and sensation disorders HLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-003976-20 Sponsor Protocol Number: GRC6211-201 Start Date*: 2007-09-12
    Sponsor Name:GLENMARK PHARMACEUTICALS SA
    Full Title: A randomised, double blind, placebo and active controlled, parallel group study to evaluate the analgesic effect of a single dose of GRC 6211, a TRPV1 receptor antagonist on pain following third...
    Medical condition: treatment of pain following third molar extraction
    Disease: Version SOC Term Classification Code Term Level
    10056350 PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2019-000736-25 Sponsor Protocol Number: IB3M.2019 Start Date*: 2019-09-05
    Sponsor Name:Universidad Complutense de Madrid
    Full Title: Efficacy of Non-Steroidal Anti-Inflammatory (Ibuprofen) Chronotherapy in Healing After Mandibular Third Molar Surgical Extraction – A Randomized Clinical Trial
    Medical condition: The clinical trial will try to understand if the elimination of the ibuprofen dosage in resting phase after surgical third molar extraction not jeopardize the postoperative period .
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-006252-19 Sponsor Protocol Number: 1.0. Start Date*: 2008-07-24
    Sponsor Name:Univ.-Prof. DDr. Norbert Jakse, Universitätszahnklinik Graz, Dep. f. Orale Chirurgie u. Röntgenologi
    Full Title: Einfluss von peroraler Methylprednisolon-Gabe auf die postoperative Morbidität nach operativer Weisheitszahnenfernung im Unterkiefer. (Influence of peroral Methylprednisolone administration on the...
    Medical condition: To be investigated is the anti-inflammatory and anti-oedematous effect of methylprednisolone on the postoperative sequelae after surgical removal of lower third molars. 16 healthy patients will und...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2018-004083-62 Sponsor Protocol Number: steroid3848 Start Date*: 2019-09-06
    Sponsor Name:Semmelweis University, Oro-Maxillofacial Surgery and Stomatology
    Full Title: Effect of preoperative intramasseteric methylprednisolone injection on the post-operative sequelae of lower third molar surgery: a placebo controlled, randomized, double-blinded study
    Medical condition: post-operative swelling, trismus, pain
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: HU (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2015-005426-19 Sponsor Protocol Number: 51237 Start Date*: 2016-02-09
    Sponsor Name:Rigshospitalet, Copenhagen University Hospitals
    Full Title: "Effect of High-dose Target-controlled Naloxone Infusion on Pain and Hyperalgesia in Patients following Recovery from Impacted Mandibular Third Molar Extraction. A Randomized, Placebo-controlled, ...
    Medical condition: Healthy volunteers (n = 94) are included. The main study includes 14 subjects who have had an uncomplicated, impacted mandibular, third molar extraction 4-5 weeks prior to participation in the stud...
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004867 10049475 Chronic pain LLT
    Population Age: Adults Gender: Male
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2016-000592-24 Sponsor Protocol Number: MR308-3501 Start Date*: 2017-03-15
    Sponsor Name:Mundipharma Research GmbH & Co. KG
    Full Title: A Randomized, Double-Blind, Multicenter, Placebo- and active Comparator-Controlled Study to evaluate Efficacy and Safety of MR308 in the Treatment of Acute Pain After Third Molar Tooth Extraction (...
    Medical condition: Acute pain after third molar tooth extraction; dental procedure must have involved extraction of at least two impacted third molars requireing bone removal. If only two impacted third molars are ex...
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000023314 10066714 Acute pain LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed) PL (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2006-001133-18 Sponsor Protocol Number: PH-2006-1 Start Date*: 2006-05-25
    Sponsor Name:Pharmos Corp.
    Full Title: CANNABINOR DENTAL IMPACTION PAIN STUDY PROOF-OF-CONCEPT DOSE-RANGING STUDY
    Medical condition: Cannabinor is as an analgesic and anti-inflammatory agent. By its nature, it has been designed to be more active at the CB2 peripheral receptors and have less activity at the central CB1 receptors....
    Disease: Version SOC Term Classification Code Term Level
    8.1 10033371 Pain LLT
    Population Age: Adults Gender: Male
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-005270-11 Sponsor Protocol Number: BAY1019036/15529 Start Date*: 2015-02-09
    Sponsor Name:Bayer HealthCare AG
    Full Title: Comparative Onset of Action of a Fast Release Aspirin Tablet in a Dental Impaction Pain Model
    Medical condition: pain following extraction of impacted third molars
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004856 10044049 Dental pain and sensation disorders HLT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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