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Clinical trials for Inflammation

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    2,416 result(s) found for: Inflammation. Displaying page 1 of 121.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2011-002290-36 Sponsor Protocol Number: H-1-2011-053 Start Date*: 2011-08-04
    Sponsor Name:Multidisciplinary Pain Center 7612, Rigshospitalet
    Full Title: Hyperbaric Oxygen effect on inflammation by a heat injury model in healthy male volunteers
    Medical condition: experimental Inflammation
    Disease: Version SOC Term Classification Code Term Level
    14.1 10018065 - General disorders and administration site conditions 10021961 Inflammation NOS LLT
    Population Age: Adults Gender: Male
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-002250-21 Sponsor Protocol Number: 044(D)SC04158 Start Date*: 2005-05-31
    Sponsor Name:ANGELINI
    Full Title: EVALUATION OF ANTALGIC EFFECT AND TOLERABILITY OF A NEW PARACETAMOL SYRUP DOSAGE IN PHARINGOTONSILLYTIS IN PEDIATRY. DOUBLE-BLIND VS PLACEBO STUDY, CONTROLLED VS KETOPROFEN LYSINA SALT.
    Medical condition: ANTALGIC EFFECT AND TOLERABILITY OF A NEW DOSAGE OF PARACETAMOL SYRUP IN PHARINGOTONSILLYTIS IN PEDIATRY
    Disease: Version SOC Term Classification Code Term Level
    6.1 10034835 PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2016-000331-41 Sponsor Protocol Number: CHDR1430 Start Date*: 2016-03-22
    Sponsor Name:Centre for Human Drug Research
    Full Title: A randomized, open-label, vehicle-controlled, parallel, dose-ranging study to assess the pharmacodynamics of topically applied Imiquimod in healthy volunteers
    Medical condition: none, this is a study on healthy volunteers
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004858 10062249 Skin inflammation LLT
    Population Age: Adults Gender: Male
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2022-000624-37 Sponsor Protocol Number: CLOBOF3-17IA03 Start Date*: 2022-10-05
    Sponsor Name:Laboratorios Salvat, S.A.
    Full Title: A Phase 3, multicenter, randomized, evaluator-blinded clinical trial to assess the safety and efficacy of Clobetasol propionate ophthalmic nanoemulsion, 0.05% compared to Prednisolone acetate, 1% i...
    Medical condition: Inflammation and pain associated with ocular surgery.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10015943 Eye inflammation PT
    20.0 10015919 - Eye disorders 10015958 Eye pain PT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-005429-26 Sponsor Protocol Number: CHDR2135 Start Date*: 2021-12-15
    Sponsor Name:Centre for Human Drug Research
    Full Title: Immunological characterization of TLR-7 mediated inflammation and complement activation after prolonged Imiquimod exposure in healthy volunteers
    Medical condition: Inflammation / Complement activation
    Disease: Version SOC Term Classification Code Term Level
    20.0 10018065 - General disorders and administration site conditions 10061218 Inflammation PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2022-004078-53 Sponsor Protocol Number: 83403 Start Date*: 2023-08-22
    Sponsor Name:Academic Medical Center (AMC), department of Internal Medicine
    Full Title: Specifying the anti-inflammatory effects of ziltivekimab with diverse imaging modalities and in-depth cellular phenotyping
    Medical condition: - Plaque characteristics - Systemic inflammation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2016-001119-19 Sponsor Protocol Number: A0661206 Start Date*: 2016-04-13
    Sponsor Name:Pfizer Inc.
    Full Title: Ocular Effects Of Azithromycin Oral Solution In Pediatric Patients With Pharyngitis/tonsillitis
    Medical condition: pharyngitis/tonsillitis
    Disease: Version SOC Term Classification Code Term Level
    19.0 10021881 - Infections and infestations 10034835 Pharyngitis PT
    19.0 10021881 - Infections and infestations 10044008 Tonsillitis PT
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2017-004037-93 Sponsor Protocol Number: TRACE Start Date*: 2018-01-17
    Sponsor Name:Afdeling for Rygkirurgi, Led- og Bindevævssygdomme ; Rigshospitalet - Glostrup
    Full Title: TReat-to-tArget (T2T) with seCukinumab in axial spondyloarthritis. IdEntification of MRI and biochemical biomarkers for disease activity, treatment response and structural damage progression (the T...
    Medical condition: Axial spondyloarthritis and ankylosing spondylitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-001728-23 Sponsor Protocol Number: AGO/2017/004 Start Date*: 2017-06-27
    Sponsor Name:Ghent University
    Full Title: Efficacy of golimumab in early axial spondyloarthritis (axSpA) in relation to gut inflammation, an early remission induction study (GO GUT).
    Medical condition: early axial spondyloarthritis (axSpA) in relation to gut inflammation
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2011-004878-29 Sponsor Protocol Number: NA Start Date*: Information not available in EudraCT
    Sponsor Name:St. Antonius Hospital
    Full Title: Perioperative antibiotic use in the treatment of acute calculous cholecystitis
    Medical condition: Acute calculous cholecystitis
    Disease: Version SOC Term Classification Code Term Level
    14.0 10019805 - Hepatobiliary disorders 10008612 Cholecystitis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-011913-26 Sponsor Protocol Number: 588 Start Date*: 2010-03-10
    Sponsor Name:Dr. Gerhard Mann chem.-pharm Fabrik GmbH
    Full Title: A Randomized, Multicenter, Double-Masked, Parallel-Group Dose Ranging Clinical Safety and Efficacy Evaluation of BOL-303242-X Ophthalmic Suspension versus Vehicle for the Treatment of Inflammation ...
    Medical condition: inflammation of the eye follwoing cataract surgery
    Disease: Version SOC Term Classification Code Term Level
    9.1 10015943 Eye inflammation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2020-005595-35 Sponsor Protocol Number: CHDR2036 Start Date*: 2021-02-11
    Sponsor Name:Centre for Human Drug Research
    Full Title: A dermal inflammatory challenge study to evaluate complement activation in healthy volunteers
    Medical condition: Inflammation / Complement activation
    Disease: Version SOC Term Classification Code Term Level
    20.0 10018065 - General disorders and administration site conditions 10061218 Inflammation PT
    Population Age: Adults Gender: Male
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2007-001205-17 Sponsor Protocol Number: TNF_5 Start Date*: 2007-10-02
    Sponsor Name:Medizinische Universität Graz_Universitätsklinik für Innere Medizin_Diabetes und Stoffwechsel
    Full Title: An open, mono-centre study to investigate the effect of the local application of an anti-inflammatory agent on the concentration of different cytokines in interstitial fluid af subcutaneous adipose...
    Medical condition: We want to investigate the anti-inflammatory effects of local Solu-Dacortin application on the profile and the variation in time profile of inflammatory cytokines (IL-1beta, TNF alpha, IL-6, IL-8, ...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10021959 Inflammation localized LLT
    9.1 10022078 Injection site inflammation LLT
    9.1 10045995 Unspecified local infection of skin and subcutaneous tissue LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2012-003859-12 Sponsor Protocol Number: 12-027 Start Date*: 2013-07-19
    Sponsor Name:RWTH Aachen University for the Medical Faculty, represented by Clinical Trial Center Aachen (CTC-A)
    Full Title: Linagliptin as a modulator of vascular inflammation in patients with type 2 diabetes mellitus
    Medical condition: patients with type 2 diabetes mellitus and vascular inflammation
    Disease: Version SOC Term Classification Code Term Level
    17.0 10018065 - General disorders and administration site conditions 10061218 Inflammation PT
    17.0 10027433 - Metabolism and nutrition disorders 10012601 Diabetes mellitus PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2016-004419-11 Sponsor Protocol Number: SC35 Start Date*: 2017-04-20
    Sponsor Name:Radboud university medical center
    Full Title: Safety and efficacy of interleukin-1 inhibitor anakinra for the amelioration of fever during neutropenia and mucositis in patients with multiple myeloma receiving an autologous hematopoietic stem c...
    Medical condition: Mucositis and febrile neutropenia
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004867 10028127 Mucositis LLT
    19.0 10005329 - Blood and lymphatic system disorders 10016288 Febrile neutropenia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2019-003567-21 Sponsor Protocol Number: CHDR1912 Start Date*: 2019-12-04
    Sponsor Name:Centre for Human Drug Research
    Full Title: A randomized, evaluator-blind, vehicle controlled, parallel group study to explore the effects of the anti-inflammatory drug prednisolone in a TLR4 and TLR7 challenge model in healthy volunteers
    Medical condition: None
    Disease: Version SOC Term Classification Code Term Level
    21.0 100000004858 10062249 Skin inflammation LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-016855-23 Sponsor Protocol Number: CD09/9088 Start Date*: 2010-08-20
    Sponsor Name:University of Leeds
    Full Title: Targeting systemic inflammation to improve endothelial function in obesity
    Medical condition: Healthy volunteer trial in obese subjects (body mass index 30 or greater) in which the IMP will be used to reduce inflammation by inhibiting tumour necrosis factor(TNF)-α in order to assess the eff...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2019-003088-22 Sponsor Protocol Number: R668-AD-1924 Start Date*: 2021-01-07
    Sponsor Name:Regeneron Pharmaceuticals, Inc.
    Full Title: A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel- Group Study to Evaluate the Efficacy and Safety of Dupilumab in Adult and Adolescent Patients with Moderate-to-Severe Atopic H...
    Medical condition: Atopic hand and foot dermatitis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10040785 - Skin and subcutaneous tissue disorders 10012431 Dermatitis PT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2010-019246-11 Sponsor Protocol Number: 577 Start Date*: 2010-07-15
    Sponsor Name:Bausch & Lomb Incorporated
    Full Title: A Randomized, Multicenter, Double-Blind, Parallel-Group Clinical Safety and Efficacy Evaluation of Loteprednol Etabonate Ophthalmic Gel, 0.5% versus Vehicle for the Treatment of Inflammation and Pa...
    Medical condition: Inflammation and pain following cataract surgery
    Disease: Version SOC Term Classification Code Term Level
    13.0 10015943 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2021-005602-10 Sponsor Protocol Number: 1.1 Start Date*: 2022-01-20
    Sponsor Name:Verein zur Förderung der Forschung auf dem Gebiet der Arteriosklerose, Thrombose und vaskulären Biologie (ATVB)
    Full Title: POESIA Study: Pleiotropic effects of PCSK 9 inhibition and bempedoic acid - Changes in Platelet Function and Inflammation Markers
    Medical condition: platelet activity and inflammation markers in patients with coronary artery disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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