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Clinical trials for Intravenous Morphine

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44347   clinical trials with a EudraCT protocol, of which   7375   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    191 result(s) found for: Intravenous Morphine. Displaying page 1 of 10.
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    EudraCT Number: 2009-014892-31 Sponsor Protocol Number: MAIVECMOPAIN Start Date*: 2009-11-10
    Sponsor Name:ErasmusMC - Sophia
    Full Title: Morphine intravenous vs. Paracetamol intravenous in children on ECMO
    Medical condition: Patients treated with Extra Corporal Membrane Oxygenation (ECMO) receive morphine as standardised analgesic drug. Morphine is associated with several side effects. In these patients a non-opioid dr...
    Disease:
    Population Age: Preterm newborn infants, Newborns, Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-005903-34 Sponsor Protocol Number: KKSMUW2011-09 Start Date*: 2012-05-04
    Sponsor Name:G. L. Pharma GmbH
    Full Title: Phase II, single centre, double blinded, cross-over dose confirmation study using two morphine-naloxone i.v. solutions
    Medical condition: Treatment of opioid dependence
    Disease:
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2007-005619-24 Sponsor Protocol Number: NL-MAIV-10-2007 Start Date*: 2007-12-06
    Sponsor Name:ErasmusmMC/ Sophia Children Hospital
    Full Title: Morphine intravenous vs. Acetaminophen intravenous in neonates and young infants undergoing major non-cardiac surgery.
    Medical condition: Patients after non-cardiac thoracic or abdominal major surgery receive Morphine as pain relief medication whereas this is associated with Morphine related side effects. In these patients a non-opio...
    Disease:
    Population Age: Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-002623-29 Sponsor Protocol Number: Lundbeckstudy2016 Start Date*: 2016-08-29
    Sponsor Name:Aalborg Universitets Hospital
    Full Title: The Effect of Morphine on the Human Central Nervous System
    Medical condition: Healthy volunteers (Brain response to i.v. morphine)
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2007-003722-18 Sponsor Protocol Number: 24862486 Start Date*: 2007-12-10
    Sponsor Name:St. Antonius Ziekenhuis
    Full Title: Randomized clinical trial of the optimization of procedural pain control in Intensive Care patients
    Medical condition: all patients admitted to the ICU of the St. Antonius hospital (>18 years old)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-003427-14 Sponsor Protocol Number: AHUS_PAL_21_01 Start Date*: 2021-12-20
    Sponsor Name:Akershus University Hospital
    Full Title: A randomized controlled trial of subcutaneous versus intravenous morphine when switching from oral to parenteral route in palliative cancer patients
    Medical condition: Cancer pain not responding to oral opioids in palliative cancer patient, where switching to the parenteral route is indicated.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-001783-21 Sponsor Protocol Number: 3288 Start Date*: 2012-07-11
    Sponsor Name:Childrens's Research Institute
    Full Title: Optimizing Pain Treatment in Pre-Term Neonates
    Medical condition: Critically Ill Premature Neonates between 23 and 32 weeks of gestation who are receiving morphine as part of their routine medical management of pain or other medically indicated condition for whic...
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10056350 Pain management PT
    Population Age: Preterm newborn infants, Under 18 Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2006-001814-34 Sponsor Protocol Number: OPI 04/006 Start Date*: 2006-09-12
    Sponsor Name:The Norwegian University of Science and Technology
    Full Title: Effects of hypothermia on the disposition of morphine, fentanyl, midazolam and propofol in intensive care unit patients
    Medical condition: Patients treated with therapeutic hypothermia (33-34 °C) and a control group of normothermic patients matched on sex, age and duration of morphine infusion.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Completed)
    Trial results: View results
    EudraCT Number: 2010-023844-34 Sponsor Protocol Number: ParCS Start Date*: 2011-06-30
    Sponsor Name:Sint Maartenskliniek
    Full Title: Effectiveness and safety of parecoxib in children undergoing scoliosis surgery compared to placebo: a double-blinded randomised controlled trial
    Medical condition: Postoperative pain in children after scoliosis surgergy (spinal fusion). The morphine consumption on the first two postoperative days will be assessed. Children: <18 years old, ASA I or II
    Disease: Version SOC Term Classification Code Term Level
    12.1 10039727 Scoliosis surgery PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-008527-14 Sponsor Protocol Number: Q8012-001 Start Date*: 2009-06-02
    Sponsor Name:University of Witten/Herdecke
    Full Title: A Randomized, Double-Blind, Active Controlled Study Comparing the Intravenous Dose of Morphine and Oxycodone Combined in a Ratio of 1:1 Versus Morphine Alone Required to Achieve Effective Pain Cont...
    Medical condition: To determine whether the intravenous coadministration of morphine and oxycodone has fewer opioid related adverse effects (AEs) than morphine alone at doses that result in effective and equi-analges...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10036276 Postoperative analgesia LLT
    9.1 10054710 Postoperative hip pain LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-002239-97 Sponsor Protocol Number: P060402 Start Date*: 2007-11-22
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title: Ketamine en association avec une PCA morphine dans le traitement analgésique postopératoire de patients opérés de prothèse totale de hanche (PTH)
    Medical condition: Patients opérés d'une prothèse totale de hanche
    Disease: Version SOC Term Classification Code Term Level
    8.1 10036276 Postoperative analgesia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-002625-20 Sponsor Protocol Number: SC052021 Start Date*: 2021-08-31
    Sponsor Name:University Hospitals Leuven
    Full Title: Intrathecal morphine administration for minimally invasive pancreatic surgery: A double blind, prospective randomized placebo-controlled trial.
    Medical condition: postoperative pain treatment after minimally invasive pancreatic surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2013-001665-16 Sponsor Protocol Number: 1312 Start Date*: 2013-08-01
    Sponsor Name:University Hospital Grenoble
    Full Title: Intranasal Sufentanyl analgesia Versus Morphine IV in Emergency room.
    Medical condition:
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2017-004038-28 Sponsor Protocol Number: Zalviso Start Date*: 2018-02-21
    Sponsor Name:Universitair Ziekenhuis Brussel
    Full Title: Comparative Prospective Randomized Study in Postoperative Cardiac Surgery Patients on Analgesia with Morphine Continuous Infusion or Sublingual Sufentanil (Zalviso®).
    Medical condition: -Postoperative pain treatment after cardiac surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2014-004088-19 Sponsor Protocol Number: TCI-PCA-002 Start Date*: 2014-12-12
    Sponsor Name:Universitätsklinikum Erlangen
    Full Title: Postoperative pain treatment after elective cardiac surgery using patient-controlled target-controlled infusion (TCI-PCA) with hydromorphone vs. patient-controlled analgesia (PCA) with morphine
    Medical condition: Postoperative pain treatment after elective cardiac surgery
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004865 10036236 Postoperative pain relief LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-002024-41 Sponsor Protocol Number: P051048 Start Date*: 2007-02-12
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title: Etude de l'efficacité de la kétamine à faibles doses analgésiques, en association avec les morphiniques, dans le traitement de la douleur cancéreuse rebelle
    Medical condition: Analgésie , traitement de la douleur cancéreuse rebelle
    Disease: Version SOC Term Classification Code Term Level
    8.1 10058019 Douleur cancéreuse rebelle PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-001499-73 Sponsor Protocol Number: GDW04/2014Amendment1 Start Date*: 2014-07-31
    Sponsor Name:University Hospitals Leuven
    Full Title: Transversus abdominis plane blok, continous systemic administration of lidocain and patient controlled intravenous morphine - 3 methods for postoperative pain control after laparoscopic colorectal ...
    Medical condition: postoperative pain
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004865 10036236 Postoperative pain relief LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2015-001835-20 Sponsor Protocol Number: OZBS12.15060 Start Date*: 2016-01-20
    Sponsor Name:Erasmus MC
    Full Title: Morphine intravenous vs. paracetamol intravenous after cardiac surgery in neonates and infants.
    Medical condition: congenital cardiac defects
    Disease:
    Population Age: Newborns, Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing) BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-002824-19 Sponsor Protocol Number: NA Start Date*: 2021-08-12
    Sponsor Name:CHU de Liège
    Full Title: Study of the hypnotic and anti-nociceptive components of Magnesium using Electroencephalogram Spectral Entropy and pupillometry during total intravenous general anesthesia : a randomized double-bli...
    Medical condition: Total thyroidectomy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-003795-37 Sponsor Protocol Number: CCR2644 Start Date*: 2005-10-31
    Sponsor Name:The Royal Marsden NHS Foundation Trust
    Full Title: Response to Parenteral Morphine and Oxycodone in Acute Pain.
    Medical condition: Post operative pain control in patients who have undergone major breast surgery for underlying breast cancer. Major breast surgery constitutes; • Mastectomy • Axillary clearance +/- wide local ex...
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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