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Clinical trials for Isosorbide mononitrate

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44336   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    8 result(s) found for: Isosorbide mononitrate. Displaying page 1 of 1.
    EudraCT Number: 2005-001004-39 Sponsor Protocol Number: JO-3 Start Date*: 2005-07-05
    Sponsor Name:University of Edinburgh
    Full Title: Investigation of combined phosphodiesterase 5 inhibitor and isosorbide mononitrate for the treatment of resistant hypertension
    Medical condition: Hypertension
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2012-002988-10 Sponsor Protocol Number: 1392GJK303 Start Date*: 2012-11-19
    Sponsor Name:Fundación para la investigacion Biomedica
    Full Title: Randomized, double-blind, placebo-controlled trial to compare the effect, three months of follow-on pulse pressure and vascular function of isosorbide mononitrate extended release, associated with ...
    Medical condition: Refractory isolated systolic hypertension
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-006981-40 Sponsor Protocol Number: hypertension2006-006981-40 Start Date*: 2007-05-03
    Sponsor Name:Cambridge University Hospitals NHS Foundation Trust jointly with University of Cambridge
    Full Title: Does the underlying haemodynamic abnormality determine response to antihypertensive therapy in patients with hypertension?
    Medical condition: Essential hypertension
    Disease: Version SOC Term Classification Code Term Level
    9.1 10004254 Benign essential hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) EE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-002277-35 Sponsor Protocol Number: AC16093 Start Date*: 2017-06-01
    Sponsor Name:University of Edinburgh [...]
    1. University of Edinburgh
    2. NHS Lothian
    Full Title: LACunar Intervention (LACI-2) Trial-2: Assessment of safety and efficacy of cilostazol and isosorbide mononitrate to prevent recurrent lacunar stroke and progression of cerebral small vessel disease.
    Medical condition: lacunar (small vessel) ischaemic stroke
    Disease: Version SOC Term Classification Code Term Level
    20.1 10029205 - Nervous system disorders 10071043 Basal ganglia stroke PT
    20.0 10029205 - Nervous system disorders 10068644 Brain stem stroke PT
    20.0 10029205 - Nervous system disorders 10023987 Late effects of cerebrovascular disease LLT
    20.0 10029205 - Nervous system disorders 10061256 Ischaemic stroke PT
    20.0 10029205 - Nervous system disorders 10042244 Stroke LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2013-004316-22 Sponsor Protocol Number: Nitrate001 Start Date*: 2014-04-17
    Sponsor Name:
    Full Title: INFLUENCE OF NITRATES ON BONE REMODELLING AND ENDOTHELIAL FUNCTION IN PATIENTS WITH TYPE 2 DIABETES MELLITUS
    Medical condition: ENDOTHELIAL DYSFUNCTION AND BONE REMODELLING
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004848 10067225 Biochemical markers of bone metabolism HLT
    16.1 10047065 - Vascular disorders 10048554 Endothelial dysfunction PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2008-006328-75 Sponsor Protocol Number: P071212 Start Date*: 2009-05-11
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title: NOCETER essai multicentrique randomisé en double aveugle contre placebo. Réduction du taux de CEsariennes chez les patientes dépassant le TERme: Impact d'une maturation cervicale ambulatoire par do...
    Medical condition: Chez les femmes qui ont dépasser le terme d'accouchement (41 SA+0)
    Disease: Version SOC Term Classification Code Term Level
    8.1 10036656 Dépassement du terme d'accouchement (41SA+0) PT
    Population Age: Adults Gender: Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-000414-20 Sponsor Protocol Number: CHANCE-HF Start Date*: 2011-08-02
    Sponsor Name:Consorcio de Apoyo a la Investigacion Biomedica en Red (CAIBER)
    Full Title: Ensayo aleatorizado controlado sobre la terapia guiada por el antígeno carbohidrato 125 en los pacientes dados de alta por insuficiencia cardiaca aguda: efecto sobre la mortalidad a 1 año.
    Medical condition: acute heart failure
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10007556 Cardiac failure acute PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-001953-33 Sponsor Protocol Number: PrevSVD-2015 Start Date*: 2015-10-09
    Sponsor Name:University of Edinburgh [...]
    1. University of Edinburgh
    2. NHS Lothian
    Full Title: Preventing cognitive decline and dementia from cerebral small vessel disease
    Medical condition: Lacunar (small vessel) ischaemic stroke
    Disease: Version SOC Term Classification Code Term Level
    19.0 10029205 - Nervous system disorders 10023987 Late effects of cerebrovascular disease LLT
    19.0 10029205 - Nervous system disorders 10042244 Stroke LLT
    19.0 10029205 - Nervous system disorders 10061256 Ischaemic stroke PT
    19.0 10029205 - Nervous system disorders 10068644 Brain stem stroke PT
    19.0 10029205 - Nervous system disorders 10071043 Basal ganglia stroke PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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