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Clinical trials for Jaw

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    83 result(s) found for: Jaw. Displaying page 1 of 5.
    1  2  3  4  5  Next»
    EudraCT Number: 2019-004704-35 Sponsor Protocol Number: BTX1-myalgia_pain Start Date*: 2020-05-18
    Sponsor Name:Region Örebro
    Full Title: Masseter myofascial pain relief following an intra-muscular injection with botulinum toxin type A. A randomized double-blind controlled multicenter pilot study.
    Medical condition: Myalgia of jaw muscle
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2005-003391-37 Sponsor Protocol Number: Scil-MD05-C01 Start Date*: 2005-12-05
    Sponsor Name:Scil Technology GmbH
    Full Title: Pilot Study on Safety and explorative Efficacy of MD05 in Comparison with the Medical Device Beta-TCP Mixed with Autogenous Bone Material in Patients Undergoing Two-Stage Unilateral Maxillary Sinus...
    Medical condition: Requirement of two-stage unilateral maxillary sinus floor augmentation in case of insufficient bone height in the area of the posterior maxilla, prior to insertion of dental implants.
    Disease: Version SOC Term Classification Code Term Level
    8.0 10061257 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-003365-34 Sponsor Protocol Number: Artralgia1 Start Date*: 2013-10-25
    Sponsor Name:Specialisttandvårdskliniken Västmanlands sjukhus Västerås
    Full Title: Pain relief following an intra-articular single dose metylprednisolon vs. placebo on temporomandibular joint artralgia patientens. A randomized controlled blinded multicenter study.
    Medical condition: Artralgia of the jaw joint
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-003817-28 Sponsor Protocol Number: 2014-003817-28 Start Date*: 2015-09-21
    Sponsor Name:Region Östergötland
    Full Title: Does bisfosfonat preserve the bone volume in transplanted bone in the jaw?
    Medical condition: Jaw abnormality
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-001972-55 Sponsor Protocol Number: 20963.091.08 Start Date*: 2009-09-30
    Sponsor Name:UMC St Radboud
    Full Title: Efficacy of hyperbaric oxygen therapy in the treatment of late radiation damage, osteoradionecrosis, of the lower jaw.
    Medical condition: Osteoradionecrosis of the jaw due to previous radiotherapy treatment in the head and neck region
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2006-007024-34 Sponsor Protocol Number: Stom2009 Start Date*: 2009-12-28
    Sponsor Name:General Teaching Hospital
    Full Title: Treatment of alveolar osteitis using ozonated water
    Medical condition: Complication after tooth extraction - alveolar osteitis (dry socket). There is no causal treatment of alveolar osteitis. That’s why symptomatic therapy is used. Disinfectants are the most important...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10013787 Dry socket LLT
    12.0 10013787 Dry socket LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-007842-36 Sponsor Protocol Number: DAHANCA-21 Start Date*: 2008-05-05
    Sponsor Name:Lone Elisabeth Forner
    Full Title: Hyperbaric oxygen treatment of mandibular osteoradionecrosis. A randomized clinical trial.
    Medical condition: Mandibular osteoradionecrosis occuring from radiation treatment of cancer. No healthy volunteers
    Disease: Version SOC Term Classification Code Term Level
    19.0 10028395 - Musculoskeletal and connective tissue disorders 10064658 Osteonecrosis of jaw PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed) SE (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2014-004682-24 Sponsor Protocol Number: DC0071BB405 Start Date*: 2015-04-27
    Sponsor Name:Institut de Recherche Pierre Fabre - Centre de R&D Pierre Fabre
    Full Title: Efficacy of DC071 mouthwash (0,2 % chlorhexidine digluconate) in peri-surgical care for preventing alveolar osteitis after third molar extraction. Prospective, multicenter, randomised, double-blin...
    Medical condition: Prevention of alveolar osteitis after third molar extraction
    Disease: Version SOC Term Classification Code Term Level
    18.1 10021881 - Infections and infestations 10066995 Alveolar osteitis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: EE (Completed) LV (Completed) LT (Completed) FR (Completed) ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-012222-36 Sponsor Protocol Number: 1.0 Start Date*: 2009-07-23
    Sponsor Name:Medizinische Universität Wien, Bernhard Gottlieb Universitätszahnklinik
    Full Title: Verification of an oro-antral communication after tooth extraction in the upper jaw. A Pilot-study
    Medical condition:
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-006225-27 Sponsor Protocol Number: SP000283 Start Date*: 2008-12-15
    Sponsor Name:The University of Liverpool [...]
    1. The University of Liverpool
    2. Aintree University Hospital NHS Trust
    Full Title: Hyperbaric Oxygen to Prevent Osteoradionecrosis of the Irradiated Mandible (HOPON)
    Medical condition: Osteoradionecrosis (ORN) of the irradiated mandible; the most feared complication of radiotherapy for head and neck cancer.
    Disease: Version SOC Term Classification Code Term Level
    19.1 10028395 - Musculoskeletal and connective tissue disorders 10064658 Osteonecrosis of jaw PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2022-002669-13 Sponsor Protocol Number: 87RI21_0052 Start Date*: 2022-11-25
    Sponsor Name:Limoges University Hospital
    Full Title: The PENTO protocol in Medication-related osteonecrosis of the jaw (MRONJ): a single-center phase IIa trial
    Medical condition: Medication-related osteonecrosis of the jaw (MRONJ)
    Disease: Version SOC Term Classification Code Term Level
    23.1 100000004859 10084881 Medication-related osteonecrosis of jaw LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2013-005305-31 Sponsor Protocol Number: 2013v01 Start Date*: 2014-03-24
    Sponsor Name:Folktandvården Östergötland
    Full Title: Ice as topical anaesthesia before injection in the oral mucosa –a randomized unblinded cross-over study in adolescents. Comparison between ice and lidokain gel 5%.
    Medical condition: The patients should be < 20 years and reffered by an orthodontist with two contra lateral premolars in the upper jaw that has to be extracted. They should not have any diseases or medications that,...
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-003139-50 Sponsor Protocol Number: Maxillo1 Start Date*: Information not available in EudraCT
    Sponsor Name:University of Bergen, Faculty of medicin and dentistry, Dep. of Clinical Dentistry
    Full Title: International, multicenter phase II uncontrolled prospective clinical trial: Jaw bone reconstruction using a combination of biomaterial and autologous mesenchymal stem cells prior to dental impla...
    Medical condition: Men and women aged 18 years or more requiring jaw bone reconstruction prior to dental implant placement based on clinical and radiological examinations (CBCT Cone beam CT imaging). Areas suitable ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-002197-13 Sponsor Protocol Number: ANE_SEVPRO_2016_01 Start Date*: 2017-02-20
    Sponsor Name:Servicio de Anestesiología y Reanimación
    Full Title: IMPLICATION OF TWO ANESTHETIC TECHNIQUES: SEVOFLURANE VERSUS PROPOFOL TO REDUCE BLOOD LOSS IN ORTHOGNATHIC SURGERY
    Medical condition: Assessment of the bleeding in ortognatic surgery.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-002175-24 Sponsor Protocol Number: 2014_68 Start Date*: 2015-12-10
    Sponsor Name:Centre Hospitalier Régional et Universitaire de Lille
    Full Title: Effect of the exacyl on perioperative bleeding during surgery of orthognatism of the upper maxillary
    Medical condition: Bleeding during surgery of orthognatism of the upper maxillary
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-002784-21 Sponsor Protocol Number: 20210516 Start Date*: 2022-04-01
    Sponsor Name:Västra Götalandsregionen
    Full Title: Botulinum toxin type A as treatment for chronic myogenous orofacial pain - a radomized controlled, double-blind clinical trial
    Medical condition: Chronic myalgia (>6months) in the facial region.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2018-002096-17 Sponsor Protocol Number: EORTC-1762-STBSG Start Date*: 2020-04-21
    Sponsor Name:European Organisation for Research and Treatment of Cancer (EORTC)
    Full Title: Reduced dose-density of denosumab for maintenance therapy of unresectable giant cell tumor of bone: a multicenter phase II study "REDUCE"
    Medical condition: Giant cell tumor of bone
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004864 10005968 Bone giant cell tumor LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Completed) GB (GB - no longer in EU/EEA) DK (Completed) ES (Prematurely Ended) IT (Completed)
    Trial results: View results
    EudraCT Number: 2014-003790-41 Sponsor Protocol Number: JAN12006-01 Start Date*: 2015-05-11
    Sponsor Name:Spherium Biomed
    Full Title: Randomised, double-blinded, placebo and active comparator controlled exploratory clinical trial to assess the efficacy and safety of a triple combination of Ibuprofen, magnesium and ascorbic acid ...
    Medical condition: Temporomandibular joint dysfunction syndrome.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-002678-11 Sponsor Protocol Number: ICO-13-001 Start Date*: 2018-06-07
    Sponsor Name:Institut Català d’Oncologia
    Full Title: An open label biomarker pilot study of the antitumoral acrivity of denosumab in the pre-operative setting of early breast cancer
    Medical condition: early breast cancer
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: ES (Ongoing)
    Trial results: View results
    EudraCT Number: 2018-001597-16 Sponsor Protocol Number: none Start Date*: 2018-07-18
    Sponsor Name:Sitnikova Victoria
    Full Title: Efficacy of botulinum toxin in treating temporomandibular disorders
    Medical condition: Patients are diagnosed TMD (temporomandibular disorder) according to DC/TMD international consortium: myalgia, local myalgia, myofascial pain, myofascial pain with referral.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004859 10028323 Muscle pains HLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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