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Clinical trials for Joint disorders

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44412   clinical trials with a EudraCT protocol, of which   7421   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    582 result(s) found for: Joint disorders. Displaying page 1 of 30.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2008-006141-12 Sponsor Protocol Number: Start Start Date*: 2008-11-14
    Sponsor Name:UMCG
    Full Title: Arthrocentesis as initial treatment of arthropathy of the temporomandibular joint
    Medical condition: Arthropathy of the temporomandibular joint
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003285 Arthropathy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-002123-41 Sponsor Protocol Number: anakinrapain1 Start Date*: 2013-10-21
    Sponsor Name:Lovisenberg Diaconal Hospital
    Full Title: Effects of intraarticular IL1-Ra on pain and inflammatory mediators after knee arthroscopy –a double blind, placebo controlled study using microdialysis technique
    Medical condition: Post operative pain after diagnostic or therapeutic knee arthroscopy
    Disease: Version SOC Term Classification Code Term Level
    16.0 10028395 - Musculoskeletal and connective tissue disorders 10023213 Joint disorders HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-003395-23 Sponsor Protocol Number: HK_VL_08_2014 Start Date*: 2015-01-20
    Sponsor Name:Section for Surgical Pathophysiology, Rigshospitalet
    Full Title: Effect of preoperative intravenous highdose methylprednisolone on quadriceps muscle function, endothelial function, complement activation and glucose homeostasis in patients scheduled for total kne...
    Medical condition: Knee joint arthrosis
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004859 10003416 Arthrosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-002744-40 Sponsor Protocol Number: HK_EA_02_2014 Start Date*: 2014-09-23
    Sponsor Name:Section For Surgical Pathophysiology, Rigshospitalet
    Full Title: Preoperative intraarticular injection of methylprednisolone, in patients scheduled for total knee-arthroplasty
    Medical condition: Knee joint arthrosis with hyperalgesia and severe movement related pain
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004859 10003416 Arthrosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-000102-19 Sponsor Protocol Number: HL_VL_01_2015 Start Date*: 2015-07-07
    Sponsor Name:Section for Surgical Pathophysiology, Rigshospitalet
    Full Title: Effect of preoperative intravenous highdose methylprednisolone on orthostatic intolerance, sleeping pattern, glucose homeostasis and immune signaling in patients scheduled for total hip-arthroplasty
    Medical condition: Hip joint arthrosis
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004859 10003416 Arthrosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2011-006036-23 Sponsor Protocol Number: CMM-PRGF/ART Start Date*: 2013-01-14
    Sponsor Name:Instituto Científico y Tecnológico de Navarra
    Full Title:
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    14.1 10028395 - Musculoskeletal and connective tissue disorders 10003416 Arthrosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2009-017624-72 Sponsor Protocol Number: CMM/ART Start Date*: 2011-10-10
    Sponsor Name:Instituto Científico y Tecnológico de Navarra
    Full Title: Tratamiento de la Artrosis mediante la inyección intra-articular de Células Madre Mesenquimales de Médula Ósea
    Medical condition: Artrosis de rodilla
    Disease: Version SOC Term Classification Code Term Level
    13 10003416 Artrosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2010-020521-40 Sponsor Protocol Number: DG-EF 01/09 Start Date*: 2010-06-21
    Sponsor Name:EPIFARMA S.R.L.
    Full Title: Evaluation of therapeutic equivalence of diclofenac gel 1% formulation compared to Voltaren emulGel 1% gel in subjects with traumatic pathology: a double blind, randomized, phase III multicentre st...
    Medical condition: Painful and traumatic inflammation of the joints, muscles, tendons and ligaments.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10028393 HLGT
    9.1 10023213 HLGT
    9.1 10043237 HLGT
    9.1 10028302 HLGT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-024010-61 Sponsor Protocol Number: DRO/IV-ART-01 Start Date*: 2011-11-09
    Sponsor Name:BIOIBERICA, S.A.
    Full Title: NON-INFERIORITY CLINICAL TRIAL ON THE EFFICACY AND SAFETY OF CHONDROITIN SULFATE AND GLUCOSAMINE HYDROCHLORIDE IN COMBINATION VERSUS CELECOXIB IN PATIENTS WITH KNEE OSTEOARTHRITIS
    Medical condition: KNEE OSTEOARTHRITIS
    Disease: Version SOC Term Classification Code Term Level
    14.1 10028395 - Musculoskeletal and connective tissue disorders 10003416 Arthrosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Completed) ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-001465-20 Sponsor Protocol Number: FMLD-ARSIDOS-48 Start Date*: 2022-02-11
    Sponsor Name:Laboratorios Farmalíder S.A.
    Full Title: A double-blind, multicenter, randomized clinical trial to assess the efficacy and safety of Montelukast in patients with erosive / inflammatory arthrosis of the hands
    Medical condition: Erosive / inflammatory arthrosis of the hands
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004859 10003416 Arthrosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Temporarily Halted)
    Trial results: (No results available)
    EudraCT Number: 2013-003413-18 Sponsor Protocol Number: IM101 Start Date*: 2014-05-13
    Sponsor Name:King’s College London [...]
    1. King’s College London
    2. Guy's and St. Thomas' NHS Foundation Trust
    3. Leiden University Medical Center
    Full Title: Arthritis Prevention In the Pre-clinical Phase of RA with Abatacept.
    Medical condition: The target population for therapeutic intervention will be subjects who carry serum autoantibodies (antibodies to citrullinated protein antigens – ACPA; rheumatoid factor – RF) and who have joint p...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10003239 Arthralgia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-004254-33 Sponsor Protocol Number: IFH-2014-002 Start Date*: 2015-02-26
    Sponsor Name:Infirst+ HEALTHCARE Ltd
    Full Title: A Three Arm Double blind, Randomised Multicentre Study to Investigate the Non-Inferiority of a Soft Gel Capsule of Ibuprofen Lipid Formulation (total daily dose 1200 mg) versus a Standard Soft Gel ...
    Medical condition: Episodic knee arthralgia/flaring knee pain
    Disease: Version SOC Term Classification Code Term Level
    18.0 10028395 - Musculoskeletal and connective tissue disorders 10003239 Arthralgia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-010172-21 Sponsor Protocol Number: ENJOIH01 Start Date*: 2009-08-27
    Sponsor Name:Elena Santagostino
    Full Title: An Investigator-sponsored study on rFVIIa prophylaxis in children with haemophilia A and inhibitors Estudio promovido por el investigador sobre profilaxis con rFVIIa en niños con hemofilia A e inh...
    Medical condition: Hemofilia A
    Disease: Version SOC Term Classification Code Term Level
    9.1 10056492 Haemophilia A with anti factor VIII LLT
    Population Age: Newborns, Infants and toddlers, Children, Under 18 Gender: Male
    Trial protocol: ES (Prematurely Ended) DE (Prematurely Ended) IT (Prematurely Ended) FR (Ongoing) PL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2014-003790-41 Sponsor Protocol Number: JAN12006-01 Start Date*: 2015-05-11
    Sponsor Name:Spherium Biomed
    Full Title: Randomised, double-blinded, placebo and active comparator controlled exploratory clinical trial to assess the efficacy and safety of a triple combination of Ibuprofen, magnesium and ascorbic acid ...
    Medical condition: Temporomandibular joint dysfunction syndrome.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-004049-26 Sponsor Protocol Number: MTX-071-P02 Start Date*: 2017-11-23
    Sponsor Name:Mestex
    Full Title: Lopain (MTX-071 / resiniferatoxin) An open label, single dose phase Ib/IIa study to determine the safety and clinical effects of intra-articular injections of low doses of Lopain (MTX-071) in pa...
    Medical condition: chronic osteoarthritic knee-joint pain
    Disease: Version SOC Term Classification Code Term Level
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10031161 Osteoarthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2011-004046-18 Sponsor Protocol Number: CL3-12911-040 Start Date*: 2012-02-23
    Sponsor Name:Institut de Recherches Internationales Servier
    Full Title: Knee joint replacement over 5 years in patients with knee osteoarthritis. A long term follow up study in patients of the CL3-12911-018 study.
    Medical condition: Osteoarthritis The medical condition investigated in the CL3-12911-018 study was osteoarthritis. The applied CL3-12911-040 trial, CL3-12911-018 follow-up study, is thus performed in osteoarthrit...
    Disease: Version SOC Term Classification Code Term Level
    14.1 10028395 - Musculoskeletal and connective tissue disorders 10031161 Osteoarthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) DE (Prematurely Ended) AT (Completed) BE (Completed) PL (Prematurely Ended) ES (Prematurely Ended) IT (Prematurely Ended) DK (Prematurely Ended) LT (Prematurely Ended) PT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-005065-21 Sponsor Protocol Number: AUX-CC-862 Start Date*: 2012-03-26
    Sponsor Name:Auxilium UK Limited
    Full Title: Retreatment of recurrent contractures in joints effectively treated with AA4500 (collagenase clostridium histolyticum [XIAFLEX®/XIAPEX®]) in an Auxilium-sponsored Phase 3 Study in the United States...
    Medical condition: Dupuytren's contracture
    Disease: Version SOC Term Classification Code Term Level
    14.1 10028395 - Musculoskeletal and connective tissue disorders 10013872 Dupuytren's contracture PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2019-002963-92 Sponsor Protocol Number: CLRX712A12201 Start Date*: 2020-02-05
    Sponsor Name:Novartis Pharma AG
    Full Title: A randomized, placebo-controlled, subject and investigator blinded study investigating the safety, tolerability and preliminary efficacy of 8-week treatment with intra-articular LRX712 to regenerat...
    Medical condition: Cartilage injuries
    Disease: Version SOC Term Classification Code Term Level
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10031161 Osteoarthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2011-003232-31 Sponsor Protocol Number: TDU11685-ACT12505 Start Date*: 2011-11-03
    Sponsor Name:sanofi-aventis recherche et développement
    Full Title: A two part protocol to assess, using double blind placebo control, the safety, tolerability, and pharmacokinetics of ascending single doses of a new intra-articular administration formulation of SA...
    Medical condition: KNEE OSTEOARTHRITIS
    Disease: Version SOC Term Classification Code Term Level
    14.0 10028395 - Musculoskeletal and connective tissue disorders 10031161 Osteoarthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2013-003467-60 Sponsor Protocol Number: M13-741 Start Date*: 2014-06-11
    Sponsor Name:AbbVie Deutschland GmbH & Co. KG
    Full Title: A Phase 2a Study Evaluating the Safety, Efficacy, and Pharmacodynamic Effects of ABT-981 in Patients with Knee Osteoarthritis
    Medical condition: Adult male and female patients with mild to moderate, symptomatic, radiographic and inflammatory osteoarthritis of the knee
    Disease: Version SOC Term Classification Code Term Level
    18.0 10028395 - Musculoskeletal and connective tissue disorders 10031161 Osteoarthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed) GB (Completed) NL (Completed) ES (Completed) IT (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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