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Clinical trials for Knee Pain AND Pain

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    409 result(s) found for: Knee Pain AND Pain. Displaying page 1 of 21.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2006-003513-40 Sponsor Protocol Number: Bupi-Cata-TYKS-version 1.0. Start Date*: 2006-08-21
    Sponsor Name:Kalevi Pihlajamäki
    Full Title: Intrathecal bupivacaine and clonidine for ambulatory knee arthroscopy
    Medical condition: Patients are submitted for ambulatory knee arthroscopy
    Disease: Version SOC Term Classification Code Term Level
    8.1 10023477 Knee pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-002635-23 Sponsor Protocol Number: NBF_HK_02_2018. Start Date*: 2018-10-23
    Sponsor Name:Anaesthesia Department, Hvidovre Hospital, Capital Region of Denmark.
    Full Title: Highdose steroids in High Pain Responders undergoing total knee-arthroplasty - A randomized doubleblindet controlled trial.
    Medical condition: Perioperative management of a group of High Pain Responders in total knee-arthroplasty because of kneeosteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10023469 Knee arthroplasty PT
    20.0 10042613 - Surgical and medical procedures 10003398 Arthroplasty of knee LLT
    20.1 100000004863 10054711 Postoperative pain LLT
    20.1 100000004867 10049475 Chronic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2008-003379-28 Sponsor Protocol Number: 0663-098 Start Date*: 2009-03-11
    Sponsor Name:Merck & Co., Inc.
    Full Title: A Phase III Randomized, Double-Blind, Placebo- and Active-Comparator-Controlled, Multiple-Dose, Clinical Trial to Study the Safety and Efficacy of MK-0663/Etoricoxib and Ibuprofen in the Treatment ...
    Medical condition: Pain after total knee replacement
    Disease: Version SOC Term Classification Code Term Level
    9.1 10023477 Knee pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) DE (Completed) LT (Completed) EE (Completed) HU (Completed) SI (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2018-000818-37 Sponsor Protocol Number: MTX-071-P03 Start Date*: 2018-06-28
    Sponsor Name:Grünenthal GmbH
    Full Title: A randomized, double-blind, placebo-controlled, single dose phase IIb exploratory study to document the clinical effects and safety of intra-articular injections of Lopain (MTX-071) in patients wit...
    Medical condition: chronic osteoarthritic knee joint pain
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004859 10023476 Knee osteoarthritis LLT
    20.0 100000004859 10003244 Arthritic pains LLT
    20.0 100000004859 10064238 Gonalgia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) SK (Completed) HR (Completed)
    Trial results: View results
    EudraCT Number: 2013-003051-37 Sponsor Protocol Number: 2013-07-03 Start Date*: 2013-08-28
    Sponsor Name:Kuopion yliopistollinen sairaala
    Full Title:
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    16.0 10042613 - Surgical and medical procedures 10023469 Knee arthroplasty PT
    16.0 100000004863 10054711 Postoperative pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-001099-39 Sponsor Protocol Number: SM1-KAKG-2018 Start Date*: 2018-06-08
    Sponsor Name:Naestved Hospital
    Full Title: Dexamethasone twice for pain treatment of total knee arthroplasty (DEX-2-TKA) A randomized blinded placebo-controlled clinical trial
    Medical condition: Postoperative pain after total knee arthroplasty
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10023469 Knee arthroplasty PT
    20.1 100000004863 10054711 Postoperative pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2017-002170-39 Sponsor Protocol Number: Knemo01 Start Date*: 2017-09-14
    Sponsor Name:Eksote
    Full Title: Combination of intrathecal morphine and local infiltration analgesia in treatment postoperative pain of total knee arthroplasty
    Medical condition: Postoperative pain after total knee arthroplasty
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000021309 10003398 Arthroplasty of knee LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-001981-24 Sponsor Protocol Number: MTX-071-P01 Start Date*: 2016-02-04
    Sponsor Name:Mestex
    Full Title: Lopain (MTX-071 / resiniferatoxin) An open label, dose-escalating phase I/IIa study to determine the safety and clinical effects of intra-articular injections of Lopain (MTX-071) in patients wi...
    Medical condition: Chronic osteoarthritic knee-joint pain
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004859 10023476 Knee osteoarthritis LLT
    20.0 100000004859 10003244 Arthritic pains LLT
    20.0 100000004859 10064238 Gonalgia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2020-006110-20 Sponsor Protocol Number: RepeatDoseTKAHPR2020 Start Date*: 2021-06-18
    Sponsor Name:Vejle Sygehus, Ortopædkirurgisk afdeling, Forskningsenheden (COFU)
    Full Title: Repeat dose steroid to prevent pain relapse after Total Knee Arthroplasty in patients with high pain response - A randomized blinded placebo-controlled trial
    Medical condition: Periooperative management of total knee-arthroplasty because of knee-osteoarthritis.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10023469 Knee arthroplasty PT
    20.1 100000004863 10054711 Postoperative pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-003094-10 Sponsor Protocol Number: CNTX-4975i-OA-303 Start Date*: 2018-11-27
    Sponsor Name:Centrexion Therapeutics Corp
    Full Title: An Open-label, 8-Week Study to Compare the Comfort and Ease of Use of Five Different Treatment Regimens for CNTX-4975-05 Intra-articular Injection in Subjects with Chronic, Moderate-to-Severe Osteo...
    Medical condition: The index knee must show evidence of chronic OA with a K-L grade of 1, 2, 3 or 4. Subjects who were screen failures for the United States (US) CNTX-4975i-OA-301 or CNTX-4975i-OA-304 trials may be c...
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004859 10023476 Knee osteoarthritis LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: GB (Completed) DE (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2015-001214-10 Sponsor Protocol Number: AAUH-01-2015 Start Date*: 2015-06-02
    Sponsor Name:Aalborg universitets hospital [...]
    1. Aalborg universitets hospital
    2. Ortopædkirurgisk forskningsenhed, Aalborg universitetshospital
    Full Title: Analgetic effect of perioperative klorzoxazon at total hip or knee arthroplasty
    Medical condition: Perioperative pain after incertion of hip or knee arthroplasty
    Disease: Version SOC Term Classification Code Term Level
    18.0 10042613 - Surgical and medical procedures 10023469 Knee arthroplasty PT
    18.0 10042613 - Surgical and medical procedures 10020096 Hip arthroplasty PT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2007-001151-19 Sponsor Protocol Number: DKOA21 Start Date*: 2007-08-21
    Sponsor Name:Sint Maartenskliniek
    Full Title: Placebo controlled trial to evaluate the effect on pain and function of six months treatment doxycycline in established knee osteoarthritis
    Medical condition: Osteoarthritis of the knee, mild to severe pain
    Disease: Version SOC Term Classification Code Term Level
    9.1 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2015-001136-37 Sponsor Protocol Number: CR4056-2-01 Start Date*: 2015-08-19
    Sponsor Name:Rottapharm Biotech S.r.l.
    Full Title: A randomized, double-blind, parallel group, placebo-controlled study to evaluate the efficacy, safety and tolerability of CR4056 administered for 2 weeks in patients with osteoarthritis of the knee...
    Medical condition: Moderate to severe chronic pain due to knee osteoarthritis with or without neuropathic component.
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004859 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2021-005020-38 Sponsor Protocol Number: KF7039-02 Start Date*: 2022-07-12
    Sponsor Name:Grünenthal GmbH
    Full Title: A randomized, double-blind, placebo-controlled, Phase III trial to evaluate the efficacy and safety of a single intra-articular injection of RTX-GRT7039 in adult subjects with pain associated with ...
    Medical condition: Moderate to severe pain associated with osteoarthritis of the knee
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004859 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) DK (Completed) PT (Completed) BG (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-000754-35 Sponsor Protocol Number: R118528 Start Date*: 2017-07-18
    Sponsor Name:The University of Manchester
    Full Title: The effect of Denosumab on Pain and bone Marrow Lesions in symptomatic Knee Osteo-arthritis: A Randomised Double Blind Placebo controlled Clinical Trial
    Medical condition: Knee osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004859 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-009856-19 Sponsor Protocol Number: 42160443PAI2004AmINT-2 Start Date*: 2009-12-17
    Sponsor Name:Janssen-Cilag International NV
    Full Title: A Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Study to Evaluate the Efficacy, Safety, and Tolerability of JNJ-42160443 as Adjunctive Therapy in Subjects With Moderate to Severe Knee ...
    Medical condition: moderate to severe, chronic, knee or hip pain from osteoarthritis (OA) that is not adequately controlled by standard pain therapy
    Disease: Version SOC Term Classification Code Term Level
    14.0 10028395 - Musculoskeletal and connective tissue disorders 10023477 Knee pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2021-005029-26 Sponsor Protocol Number: KF7039-01 Start Date*: 2022-08-08
    Sponsor Name:Grünenthal GmbH
    Full Title: A randomized, double-blind, placebo-controlled, Phase III trial to evaluate the efficacy and safety of intra-articular injections of RTX-GRT7039 in adult subjects with pain associated with osteoart...
    Medical condition: Moderate to severe pain associated with osteoarthritis of the knee
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004859 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) FR (Completed) NL (Completed) CZ (Completed) IT (Completed) PL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-002795-39 Sponsor Protocol Number: CQUC398A12201 Start Date*: 2022-10-14
    Sponsor Name:Novartis Farmacéutica S.A.
    Full Title: A randomized, two-arm, placebo-controlled, participant, investigator and sponsor-blinded, proof-of-concept study investigating the efficacy, safety and tolerability of QUC398 in patients with sympt...
    Medical condition: Knee osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004859 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing) FR (Trial now transitioned) NO (Completed) DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2012-004024-38 Sponsor Protocol Number: 194-P-308 Start Date*: 2013-08-06
    Sponsor Name:Novartis Consumer Health S.A.
    Full Title: A 4-week, randomized, double-blind, multi-center, vehicle-controlled, parallel group study to assess the efficacy and safety of diclofenac diethylamine 2.32% gel for the relief of signs and symptom...
    Medical condition: Knee osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004859 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: Removed from public view
    EudraCT Number: 2012-003770-11 Sponsor Protocol Number: GROSKNEEPA01 Start Date*: 2012-11-26
    Sponsor Name:C4Pain ApS
    Full Title: A multi-center, randomized parallel group pilot study to investigate the mechanism of action of tapentadol PR and oxycodone CR in subjects with osteoarthritis knee pain
    Medical condition: Osteoarthritic Knee Pain.
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004859 10029877 OA knee LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
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