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Clinical trials for Live birth

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44346   clinical trials with a EudraCT protocol, of which   7374   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    188 result(s) found for: Live birth. Displaying page 1 of 10.
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    EudraCT Number: 2016-004981-24 Sponsor Protocol Number: Plaquenil Start Date*: 2017-04-12
    Sponsor Name:Henriette Svarre Nielsen
    Full Title: Hydroxychloroquin (Plaquenil) treatment of recurrent pregnancy loss – a randomized, double blinded, placebo controlled study
    Medical condition: Recurrent pregnancy losses. Women with >3 subsequent pregnancy losses or 3 pregnancy losses of which one was a 2. trimester loss.
    Disease: Version SOC Term Classification Code Term Level
    19.1 100000004868 10072314 Pregnancy loss LLT
    Population Age: Adults Gender: Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2014-001694-14 Sponsor Protocol Number: CYD08 Start Date*: 2014-05-26
    Sponsor Name:Sanofi Pasteur SA
    Full Title: A Study of Dengue Vaccine in Healthy Toddlers Aged 12 to 15 Months in the Philippines
    Medical condition: Prevention of symptomatic dengue disease
    Disease:
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2020-005552-38 Sponsor Protocol Number: ProFET Start Date*: 2021-01-27
    Sponsor Name:Västragötalandsregionen, Sahlgrenska Universitetssjukhuset
    Full Title: Vaginal progesterone as luteal support for improvement of live birth in frozen/thawed in-vitro fertilization natural cycles; a multicenter, open, randomized trial
    Medical condition: infertility
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: SE (Trial now transitioned) IS (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2020-001069-35 Sponsor Protocol Number: IIBSP-EDA-2020-18 Start Date*: 2021-07-06
    Sponsor Name:Institut de Recerca de l’Hospital de la Santa Creu i Sant Pau – IIB Sant Pau
    Full Title: Impact of Exercise and Mediterranean diet vs Aspirin on live-birth rate and cardiovascular programming in In Vitro Fertilization (MEDITATE-IVF): a Randomized Study.
    Medical condition: Cumulative live-birth rate.
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-001714-26 Sponsor Protocol Number: CYD29 Start Date*: 2014-05-26
    Sponsor Name:Sanofi Pasteur SA
    Full Title: Immunogenicity and Safety of Yellow Fever Vaccine (Stamaril®) Administered Concomitantly with Tetravalent Dengue Vaccine in Healthy Toddlers at 12-13 Months of Age in Colombia and Peru
    Medical condition: Prevention of symptomatic dengue disease
    Disease:
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2019-000971-17 Sponsor Protocol Number: 58335 Start Date*: 2019-07-17
    Sponsor Name:UZ Brussel
    Full Title: Double trigger and ovum retrieval vs. conventional antagonist ovarian stimulation protocol in poor prognosis women undergoing IVF/ICSI: A pilot study
    Medical condition: infertility
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-000719-19 Sponsor Protocol Number: 09/100/10 Start Date*: 2011-05-05
    Sponsor Name:University of Birmingham
    Full Title: A Randomised Controlled Trial of the Efficacy and Mechanism of Levothyroxine Treatment on Pregnancy and Neonatal Outcomes in Women with Thyroid Antibodies. (TABLET: Thyroid AntiBodies and LEvoThyro...
    Medical condition: Thyroid autoimmunity and history of miscarriage or infertility.
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2018-004641-16 Sponsor Protocol Number: RG_18-272 Start Date*: 2020-02-14
    Sponsor Name:University of Birmingham
    Full Title: Letrozole or Clomifene, with or without metformin, for ovulation induction in women with polycystic ovary syndrome: a 2x2 factorial design randomised trial (The LOCI trial)
    Medical condition: Ovulation induction for women suffering from polycystic ovary syndrome
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004860 10002658 Anovulation LLT
    20.0 100000004872 10021935 Infertility, female, associated with anovulation LLT
    21.1 100000004872 10036050 Polycystic ovary LLT
    20.0 10036585 - Pregnancy, puerperium and perinatal conditions 10049550 Live birth PT
    20.0 10036585 - Pregnancy, puerperium and perinatal conditions 10049550 Live birth PT
    Population Age: Under 18, Adults Gender: Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2011-001820-39 Sponsor Protocol Number: 1984 Start Date*: 2012-12-14
    Sponsor Name:Academic medical centre
    Full Title: Levothyroxine for euthyroid women with recurrent miscarriage and thyroid autoimmunity : a randomized controlled trial
    Medical condition: Thyroid autoimmunity is associated with recurrent miscarriage and preterm birth. Thyroid autoimmunity means there is a normal thyroid function, but presence of thyroid antibodies, thyroid peroxidas...
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2019-000585-38 Sponsor Protocol Number: SQ411218 Start Date*: 2019-08-20
    Sponsor Name:University Hospitals Coventry and Warwickshire NHS Trust
    Full Title: Chronic Endometritis and Recurrent Miscarriage - The CERM trial
    Medical condition: Chronic Endometritis and Recurrent Miscarriage
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2020-002135-30 Sponsor Protocol Number: NCT04379973 Start Date*: 2021-04-28
    Sponsor Name:Antwerp University Hospital (UZA)
    Full Title: Live birth after additional tubal flushing with oil-based contrast versus no additional flushing: a randomised, multicentre, parallel group pragmatic trial in infertile women with at least one pate...
    Medical condition: Infertility defined as lack of conception despite 12 months of unprotected intercourse, or three cycles of donor insemination without pregnancy or three ovulatory ovulation induction cycles without...
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: BE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2005-005944-22 Sponsor Protocol Number: 106670 Start Date*: 2006-02-21
    Sponsor Name:GlaxoSmithKline GmbH & Co. KG
    Full Title: Open, multicenter, randomised, controlled phase IIIb study evaluating the immunogenicity and safety of subcutaneous versus intramuscular administration of GlaxoSmithKline Biologicals’ combined meas...
    Medical condition: Active immunization of healthy children aged 11 to 21 months against measles, mumps, rebella and varicella diseases
    Disease:
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2019-003468-27 Sponsor Protocol Number: PiNCv.1.1 Start Date*: 2019-11-29
    Sponsor Name:Homerton University Hospital NHS Trust
    Full Title: A Randomised Controlled trial investigating the effects of Progesterone for luteal phase support in Natural Cycles for unexplained infertility
    Medical condition: Unexplained infertility
    Disease: Version SOC Term Classification Code Term Level
    20.1 10014698 - Endocrine disorders 10049513 Luteal phase deficiency PT
    Population Age: Adults Gender: Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2009-017245-64 Sponsor Protocol Number: OG09/9146 Start Date*: 2010-09-07
    Sponsor Name:Leeds Teaching Hospitals NHS Trust
    Full Title: The effect of metformin co-treatment in hormone-replacement frozen embryo replacement cycles in women with polycystic ovary syndrome.
    Medical condition: Polycystic Ovary Syndrome
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2018-001014-15 Sponsor Protocol Number: S61372 Start Date*: 2018-06-26
    Sponsor Name:university hospital leuven
    Full Title: Frozen-thawed embryo transfer in a natural versus artificial cycle: a randomized clinical trial
    Medical condition: Patients with subfertility having frozen embryos after in vitro fertilization (IVF) or intracytoplasmatic sperm injection (ICSI)
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: BE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2014-000084-40 Sponsor Protocol Number: NT-05 Start Date*: 2014-04-07
    Sponsor Name:Nora Therapeutics, Inc.
    Full Title: A randomized, double blind, multi-center, placebo-controlled study to evaluate the efficacy, safety, and tolerability of NT100 in pregnant women with a history of unexplained recurrent pregnancy lo...
    Medical condition: Unexplained recurrent pregnancy loss. A distinct disorder from sporadic pregnancy loss and is characterized by the loss of multiple pregnancies
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004868 10072314 Pregnancy loss LLT
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-001539-29 Sponsor Protocol Number: alsbjerg1 Start Date*: 2019-10-11
    Sponsor Name:The Fertility Clinic, Skive Regional Hospital
    Full Title: Optimizing serum progesterone level during luteal phase in hormone replacement therapy frozen embryo transfer (HRT-FET) cycle – interventional and observational trial
    Medical condition: Infertility
    Disease: Version SOC Term Classification Code Term Level
    21.0 10038604 - Reproductive system and breast disorders 10021926 Infertility PT
    Population Age: Adults Gender: Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2021-001399-40 Sponsor Protocol Number: RECHMPL20_0092 Start Date*: 2021-06-02
    Sponsor Name:University hospital of Montpellier
    Full Title: Amlodipine interest in HRT (Hormone Replacement Therapy) cycle for frozen embryo transfer in the uterine pulsatility indices correction: double-blind randomized controlled trial
    Medical condition: uterine arteries pulsalility index for patients awaiting frozen embryo transfer
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: FR (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2016-004545-91 Sponsor Protocol Number: 59874 Start Date*: 2017-04-13
    Sponsor Name:VU University Medical Center, department of reproductive Medicine
    Full Title: Continuous use of Oral contraceptives as an alternative for long term Pituitary down-regulation with GnRH agonist prior to IVF/ICSI in Endometriosis patients: a randomised controlled trial (COPIE t...
    Medical condition: The research population consists of women with surgically confirmed endometriosis ASRM stage III or IV or endometrioma on transvaginal ultrasound or MRI, scheduled for an IVF/ICSI treatment.
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-000500-13 Sponsor Protocol Number: 8821 Start Date*: 2005-08-15
    Sponsor Name:University of Oxford- Research Services
    Full Title: Metformin treatment before IVF in women with ultrasound evidence of polycystic ovaries; a prospective, randomised, double blind, placebo controlled study
    Medical condition: Infertile women undergoing IVF with sonographic evidence of polycystic ovaries but without any clinical manifestations of polycystic ovarian syndrome.
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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