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Clinical trials for Lopinavir

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44346   clinical trials with a EudraCT protocol, of which   7374   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    125 result(s) found for: Lopinavir. Displaying page 1 of 7.
    1  2  3  4  5  6  7  Next»
    EudraCT Number: 2009-013648-35 Sponsor Protocol Number: PENTA 18 Start Date*: 2010-06-23
    Sponsor Name:PENTA Foundation
    Full Title: KONCERT A Kaletra ONCE daily Randomised Trial of the pharmacokinetics, safety and efficacy of twice-daily versus once-daily lopinavir/ritonavir tablets dosed by weight as part of combination antir...
    Medical condition: Paediatric HIV-1 Infection
    Disease: Version SOC Term Classification Code Term Level
    12 10021881 HIV-1 Infection SOC
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: IE (Completed) NL (Ongoing) FR (Completed) GB (Completed) ES (Completed) PT (Completed) BE (Completed) DE (Completed)
    Trial results: Removed from public view
    EudraCT Number: 2007-000438-38 Sponsor Protocol Number: CRO 682 Start Date*: 2007-04-12
    Sponsor Name:Imperial College London
    Full Title: Efficacy of Lopinavir in Pregnancy: Pharmacokinetic and Virological Studies with Kaletra melt extruded tablet formulation
    Medical condition: HIV infection
    Disease: Version SOC Term Classification Code Term Level
    9.1 10008922 Chronic infection with HIV LLT
    Population Age: Adolescents, Under 18, Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-005981-39 Sponsor Protocol Number: KMON Start Date*: 2012-03-20
    Sponsor Name:Unidad de VIH. Servicio de Enfermedades Infecciosas. Hospital de Bellvitge
    Full Title: Pilot simplification study to Lopinavir/ritonavir 800/200 mg monotherapy regimen once daily
    Medical condition: HIV-1 positive patients
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2006-006297-23 Sponsor Protocol Number: 06/Q0701/34 Start Date*: 2007-06-12
    Sponsor Name:Guy's & St Thomas' NHS Foundation Trust
    Full Title: A study of the pharmacokinetics of new formulation lopinavir/ritonavir in the genital tract and plasma of HIV infected women in pregnancy
    Medical condition: HIV during pregnancy
    Disease: Version SOC Term Classification Code Term Level
    8.1 10020180 HIV positive LLT
    Population Age: Adults Gender: Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-003066-18 Sponsor Protocol Number: GESIDA-5406 Start Date*: 2007-12-15
    Sponsor Name:Dr. Miguel Cervero
    Full Title: Estudio piloto, aleatorizado, nacional, multicéntrico, de eficacia inmunológica, comparando un régimen TARGA de tres fármacos (Tenofovir + Emtricitabina + Lopinavir/r) y cuatro fármacos (Tenofovir ...
    Medical condition: Pacientes diagnosticados de infección por VIH con CD4 < 100 células/microlitro, que comienzan por primera vez tratamiento antirretrovial.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-000748-14 Sponsor Protocol Number: M06-802 Start Date*: 2006-08-14
    Sponsor Name:Abbott GmbH & Co. KG
    Full Title: A Phase 3, Randomized, Open-label Study of Lopinavir/ritonavir Tablets 800/200 mg Once-daily Versus 400/100 mg Twice-daily when Coadministered with Nucleoside/Nucleotide Reverse Transcriptase Inhib...
    Medical condition: Antiretroviral experienced, HIV-1 Infection. Adequate ICD classification code not available.
    Disease: Version SOC Term Classification Code Term Level
    9.0 10020192 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) BE (Completed) ES (Completed) DE (Completed) IE (Completed) PT (Completed) GR (Completed) IT (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-000881-22 Sponsor Protocol Number: M10-336 Start Date*: 2008-07-17
    Sponsor Name:Abbott GmbH & Co. KG
    Full Title: A Randomized, Open-label, Study of Lopinavir/ritonavir 400/100 mg Tablet Twice-Daily + Co-formulated Emtricitabine/Tenofovir Disoproxil Fumarate 200/300 mg Once-Daily Versus Lopinavir/ritonavir 400...
    Medical condition: Treatment-naïve, HIV-1 infected subjects
    Disease: Version SOC Term Classification Code Term Level
    9.1 10020162 HIV infection CDC Group I LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) ES (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2010-023008-29 Sponsor Protocol Number: FH-10 Start Date*: 2011-01-12
    Sponsor Name:Fundación Huésped
    Full Title: Estudio Fase 3, Aleatorizado, Abierto, Controlado de Lopinavir/Ritonavir y Lamivudina versus terapia estándar en Pacientes Infectados con HIV-1 Naïve.
    Medical condition: El propósito del estudio es comparar la seguridad y la eficacia de la combinación de Lopinavir/Ritonavir más 3TC versus terapia estándar con 2 INTIs y Lopinavir/Ritonavir en pacientes infectados co...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-019446-38 Sponsor Protocol Number: LCR-MONOKAL Start Date*: 2010-06-04
    Sponsor Name:Fundació Lluita contra la SIDA
    Full Title: Estudio Exploratorio Transversal para Comparar la Eficacia Virológica en el LCR y el Estado Neurocognitivo en Pacientes Infectados por el VIH-1 en Tratamiento Prolongado (> 3 años) con Lopinavir/ri...
    Medical condition: Infección por VIH-1
    Disease: Version SOC Term Classification Code Term Level
    11 10008919 Infección crónica por VIH LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2004-001323-37 Sponsor Protocol Number: SPA-378-05-40 Start Date*: 2004-11-29
    Sponsor Name:H. 12 de Octubre [...]
    1. H. 12 de Octubre
    2. H. La Paz.
    Full Title: Phase IV-III, open-label, randomized, comparative study, to evaluate the safety and efficacy of the nucleoside supression of a triple therapy based on lopinavir-ritonavir vs. continuous triple ther...
    Medical condition: Infection by Human inmunideficiency virus
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-001605-23 Sponsor Protocol Number: HUA-COVID-19 Start Date*: 2020-05-29
    Sponsor Name:Basque Health Service
    Full Title: Effectiveness of the combined treatment with hydroxycloroquine and azithromycin vs lopinavir/ritonavir + hydroxycloroquine in hospitalized patients with confirmed COVID-19 infection
    Medical condition: Covid-19 infection
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-001430-32 Sponsor Protocol Number: M05-730 Start Date*: 2005-11-18
    Sponsor Name:Abbott GmbH & Co. KG
    Full Title: A Phase 3, Randomized, Open-label, Study of Lopinavir/ritonavir Tablets Versus Soft Gel Capsules and Once Daily Versus Twice Daily Administration, when Coadministered with NRTIs in Antiretroviral N...
    Medical condition: HIV-1 infection
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Completed) GB (Completed) DE (Completed) CZ (Completed) BE (Completed) ES (Completed) GR (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2004-000060-27 Sponsor Protocol Number: ESS100732 Start Date*: 2004-06-30
    Sponsor Name:GLAXO SMITHKLINE
    Full Title: A Phase IIIB, Randomized, Open-Label, Multicenter Study of the Safety and Efficacy of GW433908 700mg BID plus ritonavir 100mg BID Versus Lopinavir/ritonavir 400mg/100mg BID when Administered...
    Medical condition: HIV Infection
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2006-002864-24 Sponsor Protocol Number: UMCN-AKF 06.02 Start Date*: 2006-09-25
    Sponsor Name:Dept. of Clinical Pharmacy, Radboud UMC Nijmegen, The Netherlands
    Full Title: Drug interactions between ATOvaquone used in MAlaria prophylaxis and antiretroviral agents in HIV-1 infected patients (ATOMA)
    Medical condition: malaria prophylaxis in HIV patients
    Disease: Version SOC Term Classification Code Term Level
    8.1 10025494 Malaria prophylaxis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2009-012283-14 Sponsor Protocol Number: SECOND-LINE Start Date*: 2010-08-16
    Sponsor Name:National Centre in HIV Epidemiology and Clinical Research
    Full Title: A randomised open‐label study comparing the safety and efficacy of ritonavir boosted lopinavir and 2‐3N(t)RTI backbone versus ritonavir boosted lopinavir and raltegravir in participants virological...
    Medical condition: Chronic HIV infection
    Disease: Version SOC Term Classification Code Term Level
    12.0 10008919 Chronic HIV infection LLT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: IE (Completed) FR (Ongoing) GB (Completed) DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-024652-28 Sponsor Protocol Number: OLÉ Start Date*: 2011-08-08
    Sponsor Name:Fundació Clínic per a la Recerca Biomèdica
    Full Title: Estudio para evaluar la actividad y la tolerabilidad de la biterapia con lopinavir/ritonavir y 3TC en sustitución de una triple terapia que incluya lopinavir/ritonavir y 3TC ó FTC en pacientes con ...
    Medical condition: Infección VIH
    Disease: Version SOC Term Classification Code Term Level
    14.0 10021881 - Infections and infestations 10068341 HIV-1 infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-002296-16 Sponsor Protocol Number: FASTER Start Date*: 2004-11-26
    Sponsor Name:Antonio Antela López
    Full Title: Ensayo para evaluar la eficacia, seguridad y tolerabilidad, de una estrategia de simplificacion temprana a Trizivir, en pacientes con supresion virologica tras tratamiento antiretroviral con Combiv...
    Medical condition: HIV INFECTION
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-003799-35 Sponsor Protocol Number: RAL-PEP Start Date*: 2012-01-05
    Sponsor Name:Fundació Clínic per a la Recerca Biomèdica
    Full Title: Comparison of two antiretroviral regimens in HIV Post-exposure Prophylaxis: TDF-FTC (Truvada®) + Lopinavir/ritonavir (kaletra®) versus TDF-FTC (Truvada®) + raltegravir (Isentress®)
    Medical condition: HIV- post exposition prophylaxis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-001827-15 Sponsor Protocol Number: CORTIVID Start Date*: 2020-04-30
    Sponsor Name:NAVARRABIOMED - FUNDACIÓN MIGUEL SERVET
    Full Title: EARLY TREATMENT OF PNEUMONIA COVID-19 WITH GLUCOCORTICOIDS. RANDOMIZED CONTROLLED CLINICAL TRIAL
    Medical condition: CoVid-19 pneumonia in early inflammatory phase (stage II).
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-014430-25 Sponsor Protocol Number: SAI-CDV-2009-01 Start Date*: 2009-12-17
    Sponsor Name:Sociedad Andaluza de Enfermedades Infecciosas SAEI
    Full Title: Ensayo clínico abierto, aleatorizado, para comparar la calidad de vida de los pacientes VIH+ que inician monoterapia con comprimidos de LPV/r vs triple terapia que contengan un IP potenciado
    Medical condition: Pacientes infectadis por VIH-1
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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