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Clinical trials for Methacholine

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44336   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    135 result(s) found for: Methacholine. Displaying page 1 of 7.
    1  2  3  4  5  6  7  Next»
    EudraCT Number: 2007-003543-67 Sponsor Protocol Number: 2007-285-31-3 Start Date*: 2007-10-30
    Sponsor Name:Karolinska Universitetssjukhuset
    Full Title: Assessment of bronchial hyperresponsiveness in children - inhalation of Mannitol compared to eucapnic voluntary hyperventilation and methacholine provocation
    Medical condition: Three different methods to assess airway hyperresponsiveness in children with allergic asthma will be compared.
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: SE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2008-001027-59 Sponsor Protocol Number: NEO-040 Start Date*: 2008-10-21
    Sponsor Name:University of Dundee
    Full Title: A Randomised, Double-Blind, Double-Dummy Cross-Over Study to demonstrate Superiority of Fluticasone/ Salmeterol pMDI over double the dose of Fluticasone pMDI on Methacholine Hyper-Reactivity in Pat...
    Medical condition: Asthma
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-003991-39 Sponsor Protocol Number: I-025 Start Date*: 2005-12-08
    Sponsor Name:insaf, Institut für Atemwegsforschung GmbH
    Full Title: RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED CLINICAL CROSSOVER TRIAL IN ADULT ASTHMATICS EVALUATING THE EFFECT OF CONCOMITANT TWO WEEKS TREATMENT WITH MONTELUKAST (SINGULAIR™) 10 MG ONCE DAILY OR ...
    Medical condition: Intermittend or mild asthma according to the definition of the Global Initiative ofor Asthma (GINA) guidelines step 1 or step 2 (2004)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-006469-17 Sponsor Protocol Number: 2006-001 Start Date*: Information not available in EudraCT
    Sponsor Name:St Olavs Hospital, University Hospital of Trondheim [...]
    1. St Olavs Hospital, University Hospital of Trondheim
    2. Haukeland University Hospital
    Full Title: A multicenter study to investigate the Sensitivity and Specificity of Aridol (Mannitol)Challenge as compared with Methacholine Challenge to predict a diagnosis of Asthma by a Specialist Pulmonologi...
    Medical condition: The detection of bronchial hyperresponsiveness in patients with suspected asthma
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: NO (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-000576-13 Sponsor Protocol Number: INO102141 Start Date*: 2004-11-03
    Sponsor Name:GlaxoSmithKline Research & Development Limited
    Full Title: A two-centre, randomised, double-blind, double-dummy, placebo-controlled, 3-period cross-over study to evaluate the effect of treatment with repeat doses of GW274150 on the allergen-induced late as...
    Medical condition: Mild asthma
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-003765-40 Sponsor Protocol Number: Start Date*: 2007-07-09
    Sponsor Name:Organisation name was not entered [...]
    1. Organisation name was not entered
    2. Respiratory research UNit
    Full Title: Bronkial respons på inhaleret Mannitol
    Medical condition: A population study of the response to Aridol, used as an asthma diagnostic
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2006-003795-35 Sponsor Protocol Number: Griac001 Start Date*: 2006-10-03
    Sponsor Name:University Medical Center Groningen
    Full Title: Mannitol inhalations as a faster procedure for testing of airways hyperresponsiveness
    Medical condition: Detection of airway hyperresponsiveness in patients with asthma or COPD
    Disease: Version SOC Term Classification Code Term Level
    8.1 10003553 Asthma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-003566-13 Sponsor Protocol Number: AF219-009 Start Date*: 2013-11-06
    Sponsor Name:Afferent Pharmaceuticals, Inc.
    Full Title: A Randomised, Double-Blind, Double-Dummy, Placebo-Controlled, Three-Way Cross-over Study to evaluate the effect of AF-219 on methacholine hyper-reactivity in subjects with asthma.
    Medical condition: Stable Asthma
    Disease: Version SOC Term Classification Code Term Level
    17.1 10038738 - Respiratory, thoracic and mediastinal disorders 10003553 Asthma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2016-003672-47 Sponsor Protocol Number: CCD-01535BD1-01 Start Date*: 2016-12-20
    Sponsor Name:Chiesi Farmaceutici S.p.A.
    Full Title: A single dose, randomised, double blind, double dummy, placebo controlled, 3-way crossover clinical study, comparing the onset of relief from methacholine-induced bronchoconstriction with CHF1535 1...
    Medical condition: Asthma
    Disease: Version SOC Term Classification Code Term Level
    19.1 10038738 - Respiratory, thoracic and mediastinal disorders 10003553 Asthma PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2004-000211-26 Sponsor Protocol Number: D5890L00007 Start Date*: 2004-08-04
    Sponsor Name:AstraZeneca AB
    Full Title: A comperative, placebo-controlled, doubleblind, double dummy, cross over, single center phase IIIb study between formoterol alone and the fixed combination of formoterol and budesonide on airway re...
    Medical condition: Patient with stable and mild allergic asthma.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2006-004102-13 Sponsor Protocol Number: AcadMed CTU210406 Start Date*: 2006-10-16
    Sponsor Name:Hull and east yorkshire Hospitals Trust
    Full Title: An 8 week, non-selected, cohort, study to investigate whether the treatment of reflux induced cough alters associated bronchial hyperresponsiveness.
    Medical condition: Bronchial hyper-responsiveness in relation to reflux associated chronic cough
    Disease: Version SOC Term Classification Code Term Level
    8.1 10011233 Coughing and associated symptoms HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2005-005469-12 Sponsor Protocol Number: NEO-012 Start Date*: 2006-01-06
    Sponsor Name:Neolab Limited
    Full Title: A Phase III, randomised, double-blind, double-dummy cross-over study to compare two dry powder inhaled formulations of budesonide on methacholine hyper-reactivity in patients with stable, persisten...
    Medical condition: Stable, persistent, moderate asthma
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-004191-13 Sponsor Protocol Number: AVT-01/2/AST/04 Start Date*: 2007-01-23
    Sponsor Name:Avontec GmbH
    Full Title: Efficacy and safety of AVT-01 10 mg single dose in patients with mild asthma challenged with inhaled tumor necrosis factor alpha – A double-blind, randomized, placebo-controlled clinical study
    Medical condition: Male outpatients aged 18 - 65 with moderate persistent atopic asthma
    Disease: Version SOC Term Classification Code Term Level
    8.1 10003638 Atopic asthma LLT
    Population Age: Adults Gender: Male
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-005160-27 Sponsor Protocol Number: NAI009 Start Date*: 2009-02-04
    Sponsor Name:The University of Dundee
    Full Title: A proof of concept study to evaluate rebound trough airway hyper-responsiveness after single and chronic dosing with levosalbutamol and racemic salbutamol in persistent asthmatics
    Medical condition: asthma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003553 Asthma LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2004-002569-19 Sponsor Protocol Number: Final version Start Date*: 2004-12-15
    Sponsor Name:Department of Asthma, Allergy and Respiratory Science, GKT School of Medicine, King's College London
    Full Title: The effects of systemic vitamin D administration on production of interleukin-10 by peripheral blood T cells in asthmatics and controls.
    Medical condition: This trial is being conducted to test the hypothesis that short-term systemic administration of calcitriol in standard therapeutic dosages increases interleukin-10 production by peripheral blood T-...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-002950-23 Sponsor Protocol Number: SAM49071 Start Date*: 2005-12-02
    Sponsor Name:GlaxoSmithKline SA
    Full Title: A multi-centre, randomised, double blind, stratified, and parallel group study to evaluate whether a treatment strategy based on aiming for ‘Total control’ results in better airway hyper-responsive...
    Medical condition: Asthma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) DE (Completed) SE (Completed) FI (Completed) EE (Completed) LV (Completed) BE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2008-000905-12 Sponsor Protocol Number: CCD-0802-PR-0029 Start Date*: 2008-08-20
    Sponsor Name:CHIESI
    Full Title: A single dose, randomized, double blind, double dummy, placebo controlled, three-period crossover clinical study, comparing the onset of relief from methacholine induced bronchoconstriction with ...
    Medical condition: Ashtma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003553 Asthma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-004187-32 Sponsor Protocol Number: AVT-01/2/AST/02 Start Date*: 2007-01-23
    Sponsor Name:Avontec GmbH
    Full Title: Efficacy and safety of AVT-01 5 mg once daily over 7 days in patients with moderate persistent atopic asthma – A double-blind, randomized, placebo-controlled clinical study
    Medical condition: Male outpatients aged 18 - 65 with moderate persistent atopic asthma
    Disease: Version SOC Term Classification Code Term Level
    8.1 10003638 Atopic asthma LLT
    Population Age: Adults Gender: Male
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-004190-94 Sponsor Protocol Number: AVT-01/2/AST/03 Start Date*: 2007-01-23
    Sponsor Name:Avontec GmbH
    Full Title: Efficacy and safety of AVT-01 10 mg once daily over 7 days in patients with moderate persistent atopic asthma – A double-blind, randomized, placebo-controlled clinical study
    Medical condition: Male outpatients aged 18 - 65 with moderate persistent atopic asthma
    Disease: Version SOC Term Classification Code Term Level
    8.1 10003638 Atopic asthma LLT
    Population Age: Adults Gender: Male
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-000691-41 Sponsor Protocol Number: AR001 Start Date*: 2005-04-11
    Sponsor Name:Greater Glasgow Health Board, North Glasgow University Hospitals Division
    Full Title: Randomised controlled trial to evaluate the effect of statins on asthma control of patients with chronic asthma.
    Medical condition: Chronic Asthma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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