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Clinical trials for Metoprolol

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    68 result(s) found for: Metoprolol. Displaying page 1 of 4.
    1  2  3  4  Next»
    EudraCT Number: 2013-002260-10 Sponsor Protocol Number: MCL-metoprolol-IR Start Date*: 2013-07-11
    Sponsor Name:Medisch Centrum Leeuwarden
    Full Title: The effect of Roux-en-Y gastric bypass on the rate and extent of absorption of metoprolol from an immediate release tablet in female bariatric patient volunteers: a single oral dose study before an...
    Medical condition: Roux-en-Y gastric bypass
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-002274-41 Sponsor Protocol Number: MCL-metoprolol-CR Start Date*: 2013-07-11
    Sponsor Name:Medisch Centrum Leeuwaarden
    Full Title: The effect of Roux-en-Y gastric bypass on the rate and extent of absorption of metoprolol from a controlled release tablet in female bariatric patient volunteers: a single oral dose study before an...
    Medical condition: Roux-en-Y gastric bypass
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-002310-41 Sponsor Protocol Number: “MADRID-COVID” Start Date*: 2020-06-15
    Sponsor Name:IIS FUNDACION JIMENEZ DIAZ
    Full Title: Intravenous Metoprolol in Respiratory Distress Due to COVID-19: Pilot Study "MADRID-COVID"
    Medical condition: The main objective of this pilot trial is to evaluate the effect of metoprolol on biological correlates of benefit of this therapy (inflammatory markers in blood and bronchoalveolar mini-lavage, mi...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-002754-62 Sponsor Protocol Number: 2004-001 Start Date*: 2006-06-20
    Sponsor Name:University of Göttingen; Dep. of Clinical Pharmacology
    Full Title: Development of CYP2D6 genotype based dosage guidelines for the beta-blockers metoprolol and carvedilol based on hepatic clearance and resting and exercise heart rate reduction
    Medical condition: Healthy male and female volunteers
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-001908-23 Sponsor Protocol Number: 13-5-23-9-3-8-15 Start Date*: 2008-06-20
    Sponsor Name:Rigshospitalet, Department of Clinical Pharmacology
    Full Title: A randomised, double blinded, crossover study of the influence of Metoprolol on exercise induced elevation of catecholamines in healthy subjects.
    Medical condition: The medical condition to be investigated is heart failure, but this specific study is made on healthy volunteers to investigate the influence of metoprolol on exercise induced elevation of catechol...
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-003694-18 Sponsor Protocol Number: TM002 Start Date*: 2017-01-18
    Sponsor Name:Saniona A/S
    Full Title: A double-blind, randomized, placebo-controlled, multiple-dose, multi-centre safety and efficacy study of co-administration of tesofensine/metoprolol in subjects with Prader-Willi syndrome (PWS) "Se...
    Medical condition: Prader Willi syndrome (PWS)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10010331 - Congenital, familial and genetic disorders 10036476 Prader-Willi syndrome PT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: CZ (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2015-000284-14 Sponsor Protocol Number: Start Date*: 2016-01-05
    Sponsor Name:University of Calgary
    Full Title: Assessment of Metoprolol in the Prevention of Vasovagal Syncope in Aging Subjects
    Medical condition: Vasovagal Syncope
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2017-001507-76 Sponsor Protocol Number: BRONCHIOLE2017 Start Date*: 2017-09-20
    Sponsor Name:Region Örebro län
    Full Title: Beta-blockeRs tO patieNts with CHronIc Obstructive puLmonary diseasE (BRONCHIOLE) A pragmatic clinical trial with partial registry-based follow-up
    Medical condition: Chronic Obstructive Pulmonary disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2004-003595-11 Sponsor Protocol Number: 2004-06-DP-119-RKF-25 Start Date*: 2005-03-18
    Sponsor Name:Canadian Cardiovascular Collaboration, Population Health Research Institute, McMaster University
    Full Title: PeriOperative ISchemic Evaluation study
    Medical condition: Perioperative cardiac events frequently complicate non-cardiac surgery resulting in significant morbidity, mortality and cost. There is no clear evidence from RCTs on how to lower perioperative ca...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed) ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-003583-31 Sponsor Protocol Number: BCBe/05/Neb-Pao/088 Start Date*: 2006-04-12
    Sponsor Name:Berlin-Chemie AG
    Full Title: NEBIVOLOL OR METOPROLOL IN ARTERIAL OCCLUSIVE DISEASE A DOUBLE-BLIND, RANDOMISED CLINICAL Deutscher Titel: Nebivolol im Vergleich zu Metoprolol bei peripherer arterieller Verschlusskrankheit Eine ...
    Medical condition: Intermittent claudication (peripheral arterial disease) Fontaine’s stage II Deutsch: Periphere arterielle Verschlusskrankheit, Fontaine Staidum II
    Disease: Version SOC Term Classification Code Term Level
    8.0 10062585 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-015824-27 Sponsor Protocol Number: MeBN/06/NEB-CBP/001 Start Date*: 2009-12-23
    Sponsor Name:MENARINI Benelux NV/SA
    Full Title: The effects of Nebivolol/HCTZ on Central Arterial Pressure, a randomised double-blind cross-over trial
    Medical condition: Hypertension
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2006-006861-18 Sponsor Protocol Number: 20061212 Start Date*: 2007-03-26
    Sponsor Name:Department of Cardiology
    Full Title: Comparison between beta-adrenergic blockers and angiotensin II receptor antagonists for the treatment of late hypertension in patients with repaired aortic coarctation
    Medical condition: Aortic coarctation and late hypertension
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-001037-72 Sponsor Protocol Number: ABR60023 Start Date*: 2017-12-01
    Sponsor Name:Leiden University Medical Center
    Full Title: The efficacy of flEcainide Compared To metOprolol in reducing Premature ventrIcular Complexes. An open label cross-over study in pediatric patients.
    Medical condition: frequent premature ventricular contractions
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-003672-12 Sponsor Protocol Number: TM005 Start Date*: 2019-01-29
    Sponsor Name:Saniona A/S
    Full Title: A 24-week phase 2, double-blind, randomized, placebo-controlled, single-centre safety and efficacy study to evaluate overall safety and tolerability of co-administration of tesofensine and metoprol...
    Medical condition: Hypothalmic injury-induced obesity (HIO)
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004860 10013367 Disorders of the pituitary gland and its hypothalamic control LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2013-000048-24 Sponsor Protocol Number: SE-CVC02/2013 Start Date*: 2013-03-28
    Sponsor Name:Hear Center of Semmelweis University
    Full Title: Randomised clinical trial evaluating the safety and effectiveness of esmolol and metoprolol for heart rate control of patients referred to coronary CT angiography
    Medical condition: Heart rate control of patients referred to coronary computed tomography angiography (CCTA) due to suspected coronary artery disease are to investigated with esmolol and metoprolol. Acquiring diagno...
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10011078 Coronary artery disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-002265-36 Sponsor Protocol Number: CHDR1518 Start Date*: 2015-10-22
    Sponsor Name:Centre for Human Drug Research
    Full Title: A randomized, double blind, crossover, placebo controlled class-room experiment to assess the pharmacodynamics and pharmacokinetics of metoprolol in healthy volunteers with different polymorphism o...
    Medical condition: Influence of CYP2D6 polymorphism on metoprolol pharmacokinetics and pharmacodynamics in human volunteers
    Disease: Version SOC Term Classification Code Term Level
    18.0 10007541 - Cardiac disorders 10007521 Cardiac arrhythmias HLGT
    18.0 10047065 - Vascular disorders 10015488 Essential hypertension PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-005522-19 Sponsor Protocol Number: TM001 Start Date*: 2016-03-30
    Sponsor Name:Saniona, A/S
    Full Title: A DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED, MULTIPLE-DOSE, TWO-CENTRE, SAFETY AND EFFICACY STUDY OF CO-ADMINISTRATION OF TESOFENSINE/METOPROLOL TREATMENT IN SUBJECTS WITH TYPE 2 DIABETES MELLITUS
    Medical condition: Diabetes mellitus type 2
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004861 10045242 Type II diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2010-019939-35 Sponsor Protocol Number: Metocard Start Date*: 2010-08-03
    Sponsor Name:CNIC Centro Nacional de Investigaciones Cardiológicas
    Full Title: Daño por isquémia-reperfusión: nuevos datos en el conocimiento de los mecanismos de acción responsables de la cardioprotección conferida por el B-bloqueo en el infarto agudo de miocardio.Traslación...
    Medical condition: Comparar el efecto de dos regímenes de inicio de metoprolol en pacientes con infarto de miocardio (intravenoso versus oral) en el tamaño de infarto, función cardiaca y eventos cardiovasculares.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10000891 Acute myocardial infarction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-000889-11 Sponsor Protocol Number: MINOCA-BAT_2.0 Start Date*: 2019-06-24
    Sponsor Name:Department of Medical Sciences, Uppsala Universitet
    Full Title: Randomized Evaluation of Beta Blocker and ACE-Inhibitor/Angiotensin Receptor Blocker Treatment in MINOCA patients - MINOCA-BAT
    Medical condition: Myocardial infarction with non-obstructive coronary artery disease (MINOCA).
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Prematurely Ended) ES (Ongoing) NO (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-013701-34 Sponsor Protocol Number: VMMET009 Start Date*: 2011-09-01
    Sponsor Name:Hospital of the University of Munich
    Full Title: Prophylactic treatment of vestibular migraine with metoprolol: a double-blind, placebo- controlled trial
    Medical condition: vestibular migraine
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029205 - Nervous system disorders 10027599 Migraine PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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