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Clinical trials for Microbial

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    100 result(s) found for: Microbial. Displaying page 1 of 5.
    1  2  3  4  5  Next»
    EudraCT Number: 2006-000338-10 Sponsor Protocol Number: 0606 Start Date*: 2006-02-24
    Sponsor Name:NHS Lothian Health Board [...]
    1. NHS Lothian Health Board
    2. Edinburgh Research and Innovation
    Full Title: Can long term nebulised gentamicin reduce the bacterial burden, break the vicious cycle of inflammation and improve quality of life in patients with bronchiectasis?
    Medical condition: Bronchiectasis is respiratory disease with damaged airways. Such patients have frequent bacterial chest infections. The aim of our study is to assess whether nebulised gentamicin 80mg twice daily w...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2021-006510-36 Sponsor Protocol Number: NL79264.091.21 Start Date*: 2021-12-21
    Sponsor Name:Radboudumc
    Full Title: Exploring the Pharmacomicrobiomics of Depression
    Medical condition: Major Depressive Disorder
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004873 10081270 Major depressive disorder LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2010-023625-38 Sponsor Protocol Number: JF003 Start Date*: 2012-11-13
    Sponsor Name:Guy's and St Thomas' NHS Foundation Trust
    Full Title: Investigating the effect of Maraviroc on microbial translocation in HIV-1 infected individuals who are receiving antiretroviral therapy
    Medical condition: HIV
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10068341 HIV-1 infection LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2014-003121-17 Sponsor Protocol Number: DU001 Start Date*: 2014-09-09
    Sponsor Name:D.A.S.T. BIOTECH PHARM Ε.Π.Ε.
    Full Title: Randomized, double-blind intervention study of efficacy and safety of the product Vioplex-T compared with placebo in patients with open sores (pressure ulcers).
    Medical condition: Pressured Ulcers in I & II
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-004233-15 Sponsor Protocol Number: TADTRIC Start Date*: 2007-11-14
    Sponsor Name:InfectoPharm Arzneimittel und Consilium GmbH
    Full Title: Multicentric, randomized, double-blinded, vehicle-controlled, phase III-bilateral comparative study for treatment of staphylococcus superinfection in atopic dermatitis with hydrophobic Triclosan-cr...
    Medical condition: Staphylococcus super infection in atopic dermatitis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10042566 Superinfection LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-007103-32 Sponsor Protocol Number: DCS-001 Start Date*: 2008-02-27
    Sponsor Name:DermaGen AB
    Full Title: A randomized, double blinded placebo controlled study to investigate antimicrobial efficacy and safety following topical application of DPK-060. Final protocol dated 2007-12-19. CRO protocol no. Q-...
    Medical condition: Atopic dermatitis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-002119-81 Sponsor Protocol Number: MEC-2018-091 Start Date*: 2018-09-05
    Sponsor Name:Erasmus MC
    Full Title: Carriage of S. aureus and interaction with the nasal microbiome
    Medical condition: S. aureus carriage
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2020-000609-10 Sponsor Protocol Number: 2020-01-GMF-1 Start Date*: 2021-07-06
    Sponsor Name:Center for Surgical Science
    Full Title: A combined treatment with GM-CSF, fosfomycin and metronidazole for pouchitis in ulcerative colitis patients after restorative ileal pouch anal anastomosis surgery A clinical safety and proof-of-con...
    Medical condition: A combination of GM-CSF and metronidazole/fosfomycin treatment for pouchitis in Ulcerative Colitis patients after ileal-pouch-anal anastomosis surgery given as an enema or spray in the pouch.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10017947 - Gastrointestinal disorders 10036463 Pouchitis PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2014-002134-31 Sponsor Protocol Number: HLS14/01 Start Date*: 2015-07-22
    Sponsor Name:Ospedale L. Sacco - Azienda Ospedaliera-Polo Universitario
    Full Title: Evalutation of maraviroc therapy in PI-treated HIV+ patients at intermediate-low risk for cardiovascular diseases: a phase IV, randomized, open study
    Medical condition: HIV-1 infection.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-002588-40 Sponsor Protocol Number: CAIN457ADE02T Start Date*: 2016-05-31
    Sponsor Name:University Hospital Schleswig-Holstein
    Full Title: Exploratory Evaluation of Biomarkers associated with Treatment Response to Cosentyx (Secukinumab) in Psoriasis Patients
    Medical condition: moderate-to-severe psoriasis
    Disease: Version SOC Term Classification Code Term Level
    19.0 10040785 - Skin and subcutaneous tissue disorders 10037153 Psoriasis PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-003023-22 Sponsor Protocol Number: 2014-26 Start Date*: Information not available in EudraCT
    Sponsor Name:ASSISTANCE PUBLIQUE HOPITAUX DE MARSEILLE
    Full Title: Open trial with randomized withdrawal of treatment, to evaluate the efficacy of azithromycin in the treatment of bronchiectasis excluding cystic fibrosis in children (AZI-STOP study)
    Medical condition: bronchiectasis excluding cystic fibrosis in children
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-000334-59 Sponsor Protocol Number: PI2017_843_0002 Start Date*: 2018-06-05
    Sponsor Name:CHU Amiens-Picardie
    Full Title: The value of post-operative antibiotic therapy after laparoscopic appendectomy for complicated acute appendicitis (other than for generalized peritonitis): a prospective, randomized, placebo-contro...
    Medical condition: The value of post-operative antibiotic therapy after laparoscopic appendectomy for complicated acute appendicitis (other than for generalized peritonitis): a prospective, randomized, placebo-contro...
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2007-000375-42 Sponsor Protocol Number: S339.2.001 Start Date*: 2008-02-21
    Sponsor Name:Solvay Pharmaceuticals GmbH
    Full Title: A multi-center, double-blind, parallel-design, randomized, placebo-controlled, dose-ranging study to assess the efficacy and safety of oral recombinant microbial lipase (SLV339) in subjects with pa...
    Medical condition: Pancreatic exocrine insufficiency due to chronic pancreatitis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10009093 Chronic pancreatitis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed) SE (Prematurely Ended) HU (Prematurely Ended) CZ (Completed) LV (Completed)
    Trial results: View results
    EudraCT Number: 2020-000755-13 Sponsor Protocol Number: DACLEAN Start Date*: 2020-03-31
    Sponsor Name:CHU de Poitiers
    Full Title: ESTIMATION OF THE INCIDENCE OF COLONIZATION OF PERIPHERAL VENOUS CATHETERS AFTER SKIN DISINFECTION WITH 0.5% SODIUM HYPOCHLORITE, PRECEDED OR NOT BY AN APPLICATION OF 70% ETHANOL: PILOT, MONOCENTRI...
    Medical condition: Bacterial colonization of peripheral venous catheters
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004862 10069718 Bacterial colonization LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-002988-24 Sponsor Protocol Number: 0826-047 Start Date*: 2005-01-07
    Sponsor Name:Merck Sharp and Dohme de España
    Full Title: A prospective, multicenter, randomized, double-blind, pilot study to evaluate the safety, the efficacy, the tolerability, and the emergence of resistant gram-negative microorganisms in the bowel i...
    Medical condition: Community Acquired Bacterial Pneumonia with criteria of seriousness and great likelihood of polymicrobial or gram-negative microbial etiology.
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2019-001773-90 Sponsor Protocol Number: MiCROBPsA Start Date*: 2020-03-10
    Sponsor Name:AZIENDA OSPEDALIERA SANT'ANDREA
    Full Title: Metagenomic analysis of the gut microbiota in patients with psoriatic arthritis upon treatment with the jak-stat inhibitor tofacitinib: correlations with immunological, clinical and imaging markers
    Medical condition: Psoriatic Arthritis
    Disease: Version SOC Term Classification Code Term Level
    21.0 100000004859 10037160 Psoriatic arthritis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2004-005015-29 Sponsor Protocol Number: GS101-P2-CG Start Date*: 2005-08-03
    Sponsor Name:Les Laboratoires CTRS
    Full Title: A multicenter double-blind randomized study to investigate the efficacy and tolerability of three doses of GS-101 eye drops, an antisense oligonucleotide, versus placebo on inhibition of corneal ne...
    Medical condition: Patients suffering from keratitis or keratouveitits of infectious origin
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-007640-10 Sponsor Protocol Number: J&P002/2007 Start Date*: 2009-01-28
    Sponsor Name:PD Dr. med. K-H. Konz
    Full Title: Tissue pharmacokinetics of daptomycin measured by in vivo microdialysis in patients with diabetic foot infection
    Medical condition: A group of adult male or female patients with documented diabetes and bacterial soft tissue infection of the foot who must be subjected to undergo intravenous antimicrobial therapy with broad-spect...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-006153-41 Sponsor Protocol Number: J&P004/2008 Start Date*: 2009-03-30
    Sponsor Name:Medical university Graz, Department of Plastic Surgery
    Full Title: Target site pharmacokinetics of linezolid after repetitive doses in diabetic patients with bacterial foot infection
    Medical condition: The study population will consist of a representative group of adult male or female patients with documented diabetes and bacterial soft tissue infection of the foot complicated by osteomyelitis. P...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2008-006949-75 Sponsor Protocol Number: J&P005/2008 Start Date*: 2009-08-13
    Sponsor Name:Medical University Graz, Department for Plastic Surgery
    Full Title: Tissue pharmacokinetics of daptomycin measured by in vivo microdialysis in patients with diabetic foot infection
    Medical condition: A group of adult male or female patients with documented diabetes and bacterial soft tissue infection of the foot who must be subjected to undergo intravenous antimicrobial therapy with broad spect...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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