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Clinical trials for Noxious stimuli

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    9 result(s) found for: Noxious stimuli. Displaying page 1 of 1.
    EudraCT Number: 2005-004632-40 Sponsor Protocol Number: AGO 2005/ANE/propsev Start Date*: 2005-11-25
    Sponsor Name:University Hospital Ghent
    Full Title: Study on the pharmacodynamic interactions between propofol and sevoflurane during induction of anesthesia.
    Medical condition: Anesthesia
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-003172-36 Sponsor Protocol Number: 29.06.2011 Start Date*: 2011-10-07
    Sponsor Name:Department of Anaesthesia, Tampere University Hospital
    Full Title: Arousal reaction during desflurane anaesthesia
    Medical condition: The patients who undergo abdominal surgeries (laparotomy or laparoscopy) under desflurane anaesthesia will be investigated.
    Disease: Version SOC Term Classification Code Term Level
    14.0 10042613 - Surgical and medical procedures 10018060 General anaesthesia PT
    14.0 10022891 - Investigations 10014275 EEG LLT
    14.0 10029205 - Nervous system disorders 10002091 Anaesthesia PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2011-005086-20 Sponsor Protocol Number: CHDR1117 Start Date*: 2011-11-22
    Sponsor Name:Centre for Human Drug Research (CHDR)
    Full Title: Effects of paracetamol on nociception in adolescents.
    Medical condition: Nociceptive pain (disorders)
    Disease:
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2012-000730-19 Sponsor Protocol Number: HEEL-2011-02 Start Date*: 2012-08-23
    Sponsor Name:Radboud University Nijmegen Medical Centre
    Full Title: The analgesic efficacy of Δ9-THC (Namisol®) in Chronic Pancreatitis Patients Suffering From Persistent Abdominal Pain: a Randomized, Double-blinded, Placebo-controlled, Parallel Design
    Medical condition: Chronic pancreatitis with persistant abdominal pain
    Disease: Version SOC Term Classification Code Term Level
    14.1 10017947 - Gastrointestinal disorders 10033649 Pancreatitis chronic PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-000812-27 Sponsor Protocol Number: HEEL-2011-03 Start Date*: 2012-07-19
    Sponsor Name:Radboud University Nijmegen Medical Centre
    Full Title: The analgesic efficacy of Δ9-THC (Namisol®) in patients with persistent postsurgical abdominal pain: a randomized, double-blinded, placebo-controlled, parallel design’
    Medical condition: Patients with persistent postsurgical abdominal pain
    Disease: Version SOC Term Classification Code Term Level
    14.1 10022117 - Injury, poisoning and procedural complications 10060932 Postoperative adhesion PT
    14.1 10017947 - Gastrointestinal disorders 10000081 Abdominal pain PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-008339-27 Sponsor Protocol Number: A0081107 Start Date*: 2009-05-07
    Sponsor Name:Pfizer Inc., 235 East 42nd Street, New York, NY10017
    Full Title: A 17-WEEK, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PARALLEL-GROUP, MULTI-CENTER TRIAL OF PREGABALIN FOR THE TREATMENT OF CHRONIC CENTRAL NEUROPATHIC PAIN AFTER SPINAL CORD INJURY
    Medical condition: Chronic Central Neuropathic Pain after Spinal Cord Injury.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10054095 Neuropathic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: View results
    EudraCT Number: 2014-005035-13 Sponsor Protocol Number: GaPP2 Start Date*: 2015-02-13
    Sponsor Name:University of Edinburgh [...]
    1. University of Edinburgh
    2. NHS Lothian
    Full Title: GaPP 2: A multi-centre randomised controlled trial of the efficacy and mechanism of action of gabapentin for the management of chronic pelvic pain in women
    Medical condition: Chronic pelvic pain of unknown cause
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004872 10048581 Pelvic pain female LLT
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-000647-24 Sponsor Protocol Number: HEEL-2011-01 Start Date*: 2011-07-26
    Sponsor Name:Radboud University Nijmegen Medical Centre
    Full Title: The safety, tolerability, and analgesic efficacy of Δ9-THC (Namisol®) in chronic pancreatitis patients suffering from persistent abdominal pain
    Medical condition: patients with abdominal pain as a result of chronic pancreatitis
    Disease: Version SOC Term Classification Code Term Level
    13.1 10017947 - Gastrointestinal disorders 10033649 Pancreatitis chronic PT
    13.1 10017947 - Gastrointestinal disorders 10009093 Chronic pancreatitis LLT
    Population Age: Adults Gender: Male
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2009-014619-11 Sponsor Protocol Number: Kotoe_01 Start Date*: 2009-10-09
    Sponsor Name:Pirkanmaan sairaanhoitopiiri
    Full Title: The effect of dexmedetomidine on reactivity of a propofol-anaesthetized patient
    Medical condition: Surgical patients scheduled for elective surgery under general anaesthesia. Otherwise in stable medical condition (ASA status 1 or 2).
    Disease: Version SOC Term Classification Code Term Level
    12.0 10023696 Laparotomy LLT
    12.0 10023697 Laparotomy & drainage LLT
    12.0 10051777 Staging laparotomy LLT
    12.0 10053361 Explorative laparotomy LLT
    12.0 10023693 Laparoscopy LLT
    12.0 10069054 Pelvic laparoscopy LLT
    12.0 10006187 Breast cancer LLT
    12.0 10006188 Breast cancer female NOS LLT
    12.0 10006193 Breast cancer NOS recurrent LLT
    12.0 10006198 Breast cancer recurrent LLT
    12.0 10006203 Breast cancer stage unspecified LLT
    12.0 10021944 Infiltrating ductal breast cancer LLT
    12.0 10021974 Inflammatory breast cancer LLT
    12.0 10022779 Intraductal breast cancer (in situ) LLT
    12.0 10025025 Lumpectomy (breast cancer) LLT
    12.0 10027475 Metastatic breast cancer LLT
    12.0 10028058 Mucinous breast cancer LLT
    12.0 10048406 Breast cancer aggravated LLT
    12.0 10055113 Breast cancer metastatic LLT
    12.0 10057654 Breast cancer female LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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