Flag of the European Union EU Clinical Trials Register Help

Clinical trials for Off-pump coronary artery bypass

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44339   clinical trials with a EudraCT protocol, of which   7369   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
    How to search [pdf]
    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
    Advanced Search: Search tools
     
    11 result(s) found for: Off-pump coronary artery bypass. Displaying page 1 of 1.
    EudraCT Number: 2012-002316-12 Sponsor Protocol Number: SR052012 Start Date*: 2012-08-14
    Sponsor Name:University Hospitals of the KU Leuven
    Full Title: The safety and feasibility of administering xenon to patients undergoing off-pump coronary artery bypass graft surgery: a pilot study XOPCAB – Xenon in Off-Pump Coronary Artery Bypass Grafting
    Medical condition: Xenon anesthesia in cardiac surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2016-001529-15 Sponsor Protocol Number: RATIOSTUDY Start Date*: 2016-10-26
    Sponsor Name:AZIENDA SOCIO-SANITARIA TERRITORIALE DI LECCO (ASST LECCO)
    Full Title: Randomized Anticoagulation Trial In Opcab HIGH DOSE VERSUS LOW DOSE HEPARINIZATION IN PATIENTS
    Medical condition: Off-pump coronary artery bypass grafting (OPCAB) is an established alternative to on-pump coronary artery bypass grafting (CABG), OPCAB, like any other surgical procedure, determines a pro-coagulan...
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10011098 Coronary bypass LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2008-001135-35 Sponsor Protocol Number: TMC-CAN-08-02 Start Date*: 2010-02-02
    Sponsor Name:The Medicines Company
    Full Title: Maintenance of platelet inhiBition with cangreloR after dIscontinuation of thienopyriDines in patients undergoing surGEry: The BRIDGE trial
    Medical condition: Subjects who present with an acute coronary syndrome.
    Disease: Version SOC Term Classification Code Term Level
    12.0 10051592 Acute coronary syndrome LLT
    12.0 10051592 Acute coronary syndrome PT
    12.0 10006894 CABG LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) GB (Completed) AT (Completed) NL (Completed)
    Trial results: View results
    EudraCT Number: 2013-000485-11 Sponsor Protocol Number: SR022013 Start Date*: 2013-04-24
    Sponsor Name:University Hospitals of the KU Leuven
    Full Title: Xenon as an adjuvant to propofol anaesthesia in patients undergoing off-pump coronary artery bypass graft surgery: a randomized controlled trial
    Medical condition: Xenon anesthesia in cardiac surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2007-002652-42 Sponsor Protocol Number: 2007IC007H Start Date*: 2007-08-14
    Sponsor Name:Royal Brompton and Harefield NHS Trsut
    Full Title: The use of clopidogrel and aprotonin in off pump coronary artery bypass grafting
    Medical condition: Bleeding after coronary artery bypass grafting
    Disease: Version SOC Term Classification Code Term Level
    9.1 10005645 Blood loss of (NOS) LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-009657-19 Sponsor Protocol Number: S201 Start Date*: 2009-11-04
    Sponsor Name:Ikaria, Inc.
    Full Title: A randomized, double-blind, placebo-controlled, multi-center study of IK-1001 to evaluate safety, population pharmacokinetics and proof-of-concept efficacy for reduction of ischemia-reperfusion med...
    Medical condition: It will be conducted in subjects undergoing coronary artery bypass graft (CABG) surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2017-001754-33 Sponsor Protocol Number: SDAT-IRC Start Date*: 2018-10-16
    Sponsor Name:UNIVERSITÀ CAMPUS BIO-MEDICO DI ROMA
    Full Title: Single versus Dual Antiplatelet Therapy in patients with Incomplete Revascularization after Coronary artery bypass graft surgery
    Medical condition: in patients with Incomplete Revascularization after Coronary artery bypass graft surgery
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10032492 Other specified acute and subacute form of ischemic heart disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-015013-46 Sponsor Protocol Number: AnaesthesiaResearch024 Start Date*: 2009-12-14
    Sponsor Name:Alfred Health
    Full Title: The ATACAS Trial: Aspirin and Tranexamic Acid for Coronary Artery Surgery Trial
    Medical condition: Coronary Artery Bypass Grafting
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-008235-28 Sponsor Protocol Number: 82772673 Start Date*: 2009-01-28
    Sponsor Name:Vesa Pakanen
    Full Title: Parasetamolin käyttö oheiskipulääkkeenä oksikodonin kanssa ohitusleikkauksen jälkeisen kivun hoidossa Paracetamol as Adjuctive Treatment for Postoperative Pain after Off-Pump Bypass Surgery
    Medical condition: Patient with chronic ischemic heart disease ongoing elective coronary artery bypass grafting. Any major organ failures like heart, kidney, liver failures are excluded.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10008937 Chronic ischemic heart disease, unspecified LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2011-001795-19 Sponsor Protocol Number: Uni-Koeln-1341 Start Date*: 2012-09-13
    Sponsor Name:University of Cologne
    Full Title: STATIN RECAPTURE THERAPY BEFORE CORONARY ARTERY BYPASS GRAFTING (ACRONYM: START-CABG TRIAL)
    Medical condition: Patients on a long term statin therapy with established coronary artery disease (CAD) scheduled for isolated surgical myocardial revascularisation (i.e. CABG)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-003413-10 Sponsor Protocol Number: ACDHUVV-16 Start Date*: 2016-12-20
    Sponsor Name:FIMABIS
    Full Title: MicroRNAs expression analysis in patients undergoing cardiac surgery treated with halogenated anesthetics. Identification of microRNAs related to the cardioprotective effect
    Medical condition: Cardiac surgery
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    Download Options:
    Number of Trials to download:
    Download Content:
    Download Format:
    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
    Query did not match any studies.
    For support, Contact us.
    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

    European Medicines Agency © 1995-Fri May 30 18:05:23 CEST 2025 | Domenico Scarlattilaan 6, 1083 HS Amsterdam, The Netherlands
    EMA HMA