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Clinical trials for Oral

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44297   clinical trials with a EudraCT protocol, of which   7351   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    24,290 result(s) found for: Oral. Displaying page 1 of 1,215.
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    EudraCT Number: 2006-004760-31 Sponsor Protocol Number: CG/7657 Start Date*: 2007-04-17
    Sponsor Name:University of Dundee
    Full Title: Role and efficacy of topical 5-Aminolevulinic Acid (5-ALA) in Photodynamic detection (PDD) in determining malignant potential of oral lichen planus
    Medical condition: Oral Lichen Planus
    Disease: Version SOC Term Classification Code Term Level
    8.1 10030983 Oral lichen planus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-018590-38 Sponsor Protocol Number: 70421 Start Date*: 2010-04-14
    Sponsor Name:LUMC
    Full Title: The thrombogenicity of the dienogest/estradiol valerate containing oral contraceptive (Qlaira)
    Medical condition: We will investigate the thrombogenicity of two different oral contraceptives: dienogest/estradiol valerate (Qlaira) in comparison to levonorgestrel/ethinylestradiol (Microgynon-30) used by healthy ...
    Disease: Version SOC Term Classification Code Term Level
    12.1 10030971 Oral contraceptive LLT
    Population Age: Adults Gender: Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-000866-22 Sponsor Protocol Number: 01.01.08Jen Start Date*: 2008-05-15
    Sponsor Name:University of Aarhus, School of Dentistry
    Full Title: Vurdering af det operative forløb i forbindelse med fjernelse af mandiblens 3. molar med særligt henblik på forekomsten af smerte og hævelse
    Medical condition: pain after surgical removal of lower third molars
    Disease: Version SOC Term Classification Code Term Level
    9.1 10051059 Oral surgery LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-004696-35 Sponsor Protocol Number: 01/CG02/1957 Start Date*: 2007-06-08
    Sponsor Name:Greater Glasgow and Clyde Health Board
    Full Title: A pilot study into the effect of 5-Aminolevulinic Acid Photodynamic Therapy in the management of oral Lichen Planus
    Medical condition: Oral Lichen Planus
    Disease: Version SOC Term Classification Code Term Level
    8.1 10030983 Oral lichen planus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2005-004504-36 Sponsor Protocol Number: 801-00 Start Date*: 2005-12-20
    Sponsor Name:Merck & Co., Inc.
    Full Title: A Multicenter, Randomized, Double-Blind, Comparative Study to Evaluate the Safety, Tolerability, and Efficacy of 2 Dosing Regimens of Caspofungin in the Treatment of Invasive Candidiasis in Adults.
    Medical condition: Candidiasis (invasive)
    Disease: Version SOC Term Classification Code Term Level
    8.0 10007152 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) BE (Completed) IT (Completed) PT (Completed) DE (Completed) LV (Completed)
    Trial results: View results
    EudraCT Number: 2009-014833-26 Sponsor Protocol Number: IEO S500/409 Start Date*: 2010-07-29
    Sponsor Name:ISTITUTO EUROPEO DI ONCOLOGIA
    Full Title: Phase IIB Randomized, Placebo Controlled Trial of Pioglitazone for Oral Premalignant Lesions. An Inter-Consortium Collaborative Study.
    Medical condition: oral premalignant lesions
    Disease: Version SOC Term Classification Code Term Level
    9.1 10024396 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-003784-56 Sponsor Protocol Number: NV012013 Start Date*: 2014-04-15
    Sponsor Name:VUAB Pharma a.s.
    Full Title: An open, randomized, clinical trial parallel-controlled with Mycostatin oral suspension, evaluating the efficacy of Nystatin oral gel and Nystatin oral suspension in adult patients with oropharynge...
    Medical condition: Laboratory confirmed efficacy of Nystatin in pharmaceutical forms for buccal use, in patients with oropharyngeal candidiasis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: View results
    EudraCT Number: 2009-010357-12 Sponsor Protocol Number: 43/2009 Start Date*: 2009-03-16
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: Hypothalamus-Pituitary-Adrenal Axis function in the topical management with clobetasol propionate of oral lichen planus (OLP
    Medical condition: oral lichen planus
    Disease: Version SOC Term Classification Code Term Level
    9.1 10030983 Oral lichen planus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2010-023215-34 Sponsor Protocol Number: PSE-HSP-203 Start Date*: 2010-12-20
    Sponsor Name:Teva Women`s Health Research
    Full Title: A Multinational, Multicenter, Randomized, Open-Label Study to Evaluate the Impact of a 91-day Extended Cycle Oral Contraceptive Regimen, Compared to two 28-day Standard Oral Contraceptive Regimen...
    Medical condition: Healthy women taking contraceptive regimen
    Disease: Version SOC Term Classification Code Term Level
    9.1 10030971 LLT
    Population Age: Adults Gender: Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2014-004677-17 Sponsor Protocol Number: 141022 Start Date*: 2016-02-29
    Sponsor Name:Kvinnokliniken, Universitetssjukhuset i Linköping, Landstinget i Östergötland
    Full Title: Contraception after gastric bypass - part 4 How does gastric bypass affect the pharmacocinetics of oral levonorgestrel?
    Medical condition: We want to investigate if the pharmacocinetics of levonorgestrel differs in women who have had bariatric surgery compared to women who have not. Measures of serum concentrations of levonorgestrel w...
    Disease: Version SOC Term Classification Code Term Level
    18.1 10042613 - Surgical and medical procedures 10030970 Oral contraception PT
    18.1 10042613 - Surgical and medical procedures 10061966 Gastric bypass PT
    Population Age: Adults Gender: Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-000833-39 Sponsor Protocol Number: 35/04 Start Date*: 2004-10-22
    Sponsor Name:ISTITUTO NAZIONALE PER LA CURA TUMORI
    Full Title: RANDOMIZED STUDY WITH POSTOPERATIVE RADIOTHERAPY AND CONCURRENT LOW DOSE CISPLATIN VS RADIOTHERAPY AND CONCURRENT CISPLATIN + FLUOROURACIL IN OPERATED HIGH RISK SQUAMOUS CELL CARCINOMA OF T...
    Medical condition: Head and neck cancer
    Disease: Version SOC Term Classification Code Term Level
    9.1 10061325 Oral neoplasm LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-000925-30 Sponsor Protocol Number: 10 Start Date*: 2013-05-04
    Sponsor Name:Uppsala University
    Full Title: How common are mood and sexual side-effects from combined oral contraceptives?
    Medical condition: Healthy women
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10030970 Oral contraception PT
    Population Age: Adults Gender: Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2012-005797-58 Sponsor Protocol Number: 465 Start Date*: 2013-04-19
    Sponsor Name:Kvinnokliniken, Universitetessjukhuset i Linköping, landstinget i Östergötland
    Full Title: Contraception after gastric bypass - part three How does gastric bypass affect the pharmacocinetics of oral desogestrel?
    Medical condition: We want to investigate how the pharmacocinetics changes for Cerazette in 14 fertile obese women after, compared to before, bariatric surgery in forms of gastric by pass. Mesures of serum concetrati...
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10030970 Oral contraception PT
    14.1 10042613 - Surgical and medical procedures 10061966 Gastric bypass PT
    Population Age: Adults Gender: Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-002340-42 Sponsor Protocol Number: SBG-2-03 Start Date*: 2008-09-16
    Sponsor Name:Biotec Pharmacon ASA
    Full Title: A randomized, double-blind, placebo-controlled, parallel-group phase III clinical study to assess the efficacy and safety of soluble beta 1,3/1,6 glucan (SBG) on oral mucositis in head and neck can...
    Medical condition: Oral mucositis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10028130 Mucositis oral LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-005027-81 Sponsor Protocol Number: 0 Start Date*: 2018-08-14
    Sponsor Name:Maria Siponen [...]
    1. Maria Siponen
    2. Maria Siponen
    Full Title: Chlorhexidine and nystatin in the treatment of oral candidosis - a pilot study
    Medical condition: oral candidosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-005453-36 Sponsor Protocol Number: MPC134 Start Date*: 2009-02-19
    Sponsor Name:Central and North West London NHS Foundation Trust (Camden Provider Services)
    Full Title: The Effects of Standard vs. Tailored use of the Combined Oral Contraceptive on Continuation Rates at one year.
    Medical condition: A randomised controlled trial to find out whether tailored pill use is better than standard pill use by seeing which approach leads to more women staying on the pill for at least one year.
    Disease: Version SOC Term Classification Code Term Level
    13.1 10042613 - Surgical and medical procedures 10030970 Oral contraception PT
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2017-000791-29 Sponsor Protocol Number: CICLO-LPO Start Date*: 2017-07-13
    Sponsor Name:Clínica Universidad de Navarra/Universidad de Navarra
    Full Title: Randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of cyclosporine mucoadhesive gel at two different concentrations in the topical treatment of lichen planus in ...
    Medical condition: oral lichen planus
    Disease: Version SOC Term Classification Code Term Level
    20.0 10017947 - Gastrointestinal disorders 10030983 Oral lichen planus PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-015159-26 Sponsor Protocol Number: UKW-Inf-001 Start Date*: 2011-03-14
    Sponsor Name:Universitaetsklinikum Wuerzburg
    Full Title: UKW-Inf-001: Prospective trial to evaluate pharmacokinetic, safety and efficacy of intermittent application of increased doses of caspofungin for antifungal prophylaxis in high risk patients.
    Medical condition: Prophylaxis of invasive fungal infection, including life-threatening aspergillosis and candidiasis, is investigated in the study. Patient with acute myeloid leukemia or acute lymphatic leukemia wil...
    Disease: Version SOC Term Classification Code Term Level
    12.1 10003488 Aspergillosis PT
    12.1 10042941 Systemic fungal infection NOS LLT
    12.1 10007152 Candidiasis LLT
    12.1 10036898 Prophylaxis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-006409-18 Sponsor Protocol Number: 9463-EC-0002 Start Date*: 2010-02-09
    Sponsor Name:Astellas Pharma Europe Ltd.
    Full Title: An Exploratory Study to Compare the Efficacy and Safety of Micafungin as a Pre-emptive Treatment of Invasive Candidiasis versus Placebo in High Risk Surgical Subjects - A Multicentre, Randomized, D...
    Medical condition: Invasive Candidiasis
    Disease: Version SOC Term Classification Code Term Level
    12.1 10007152 Candidiasis LLT
    12.1 10007162 Candidiasis of the intestine LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) ES (Completed) HU (Completed) BE (Completed) GR (Completed) DE (Completed) FR (Completed) FI (Completed) IT (Completed) GB (Completed) DK (Completed) NL (Completed)
    Trial results: View results
    EudraCT Number: 2005-002754-22 Sponsor Protocol Number: BUM-4/GVH Start Date*: 2006-03-14
    Sponsor Name:Dr. Falk Pharma GmbH
    Full Title: An open, randomized, multicentre phase II pilot study to evaluate the efficacy of budesonide 3 mg effervescent tablet in patients with resistant oral chronic GvHD using different application durati...
    Medical condition: oral chronic graft versus host disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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