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Clinical trials for Oxygen effect

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44338   clinical trials with a EudraCT protocol, of which   7368   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    503 result(s) found for: Oxygen effect. Displaying page 1 of 26.
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    EudraCT Number: 2012-003648-59 Sponsor Protocol Number: CH1.0 Start Date*: 2012-10-01
    Sponsor Name:Dept. of Neurology, Atrium Medical Centre
    Full Title: Oxygen treatment for cluster headache attacks at different flow rates. A double-blind, randomized, cross-over design study.
    Medical condition: To study whether there is a difference in treatment effect between oxygen at flow rates of 7 L/min versus 12 L/min in the acute treatment of cluster headache attacks.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-003714-68 Sponsor Protocol Number: 1744/2017 Start Date*: 2017-11-15
    Sponsor Name:Medical University of Vienna
    Full Title: Effect of Supplemental Oxygen on Perioperative Brain Natriuretic Peptide Concentration in Cardiac Risk Patients - A prospective randomized clinical trial
    Medical condition: Evaluation of the effect of 80% versus 30% supplemental oxygen administration during major abdominal surgery on postoperative brain natriuretic peptide concentration.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10059883 Fraction of inspired oxygen PT
    20.0 100000173317 10050322 Oxygen supplementation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2014-003858-14 Sponsor Protocol Number: HBO-SHA Start Date*: 2014-12-01
    Sponsor Name:Multidisciplinary Pain Center 7612, Rigshospitalet
    Full Title: Does Hyperbaric Oxygen Therapy Attenuate Secondary Hyperalgesia Areas Induced by a Thermal Injury in Human Volunteers? A Randomized Controlled Cross-over Study with a Blinded Observer.
    Medical condition: Experimental Inflammation
    Disease: Version SOC Term Classification Code Term Level
    17.1 10042613 - Surgical and medical procedures 10057480 Hyperbaric oxygen therapy PT
    Population Age: Adults Gender: Male
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-001387-39 Sponsor Protocol Number: 1.4 Start Date*: 2019-03-15
    Sponsor Name:Thoraxklinik-Heidelberg gGmbH
    Full Title: A prospective, randomized, controlled trial to assess the effect of long-term oxygen therapy on 6-minute walking distance, clinical parameters and hemodynamics in patients with pulmonary arterial h...
    Medical condition: pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-001763-23 Sponsor Protocol Number: 2018-001763-23 Start Date*: 2018-06-27
    Sponsor Name:Reinier van Arkel
    Full Title: Treatment of headaches post-ECT with oxygen therapy; a proof of concept study
    Medical condition: Headaches occuring after electro conculsion therapy.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-001710-32 Sponsor Protocol Number: 2006-101 Start Date*: 2006-07-05
    Sponsor Name:Dept. of Anaesthesia, Centre of Head and Orthopaedics, Copenhagen University Hospital Rigshospitalet
    Full Title: PeRioperative OXygen fraction – effect on surgical site Infection and pulmonary complications after abdominal surgery. (The PROXI-study)
    Medical condition: Laparotomy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2012-005299-32 Sponsor Protocol Number: OPHT-110912 Start Date*: 2013-01-24
    Sponsor Name:Medizinische Universität Wien, Universitätsklinik für Klinische Pharmakologie
    Full Title: Effect of breathing 100% oxygen on brain metabolites measured by 7-Tesla MRI
    Medical condition: brain metabolism
    Disease: Version SOC Term Classification Code Term Level
    14.1 10022891 - Investigations 10033316 Oxygen saturation PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2018-003687-31 Sponsor Protocol Number: AGO/2018/005 Start Date*: 2019-01-31
    Sponsor Name:Ghent University Hospital
    Full Title: Influence of continuous administration of phenylephrine versus dobutamine on spinal oxygen saturation, measured with near-infrared spectroscopy (NIRS).
    Medical condition: spinal vasculature spinal oxygen saturation muscle oxygen saturation cerebral oxygen saturation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2014-002282-30 Sponsor Protocol Number: 2014-2 Start Date*: 2014-07-30
    Sponsor Name:County council of Ostergotland
    Full Title: Effects of oxygen treatment on mechanisms involved in ischemia-reperfusion injury: A pilot study in healthy volunteers.
    Medical condition: Study performed in healthy male vonlunteers.
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-001849-39 Sponsor Protocol Number: NETs-C19 Start Date*: 2020-05-18
    Sponsor Name:Region Skåne
    Full Title: Aerosolized DNase I for the treatment of severe respiratory failure in COVID-19 - a phase 2, randomized controlled trial
    Medical condition: SARS-coronavirus-2 infection
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-003238-35 Sponsor Protocol Number: 4_141221 Start Date*: 2021-09-15
    Sponsor Name:Oslo University Hospital
    Full Title: Effects of supplemental oxygen on systemic and cerebral hemodynamics in experimental hypovolemia: A randomized, phase IV, crossover study to study the effect of supplemental oxygen vs. room air on ...
    Medical condition: Hypovolemia is the condition under investigation. Hypovolemia is induced by the "lower body negative pressure" (LBNP)-model.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10047065 - Vascular disorders 10049771 Shock haemorrhagic PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NO (Completed)
    Trial results: View results
    EudraCT Number: 2014-003380-38 Sponsor Protocol Number: Oxyperform Start Date*: 2014-09-23
    Sponsor Name:R&D department, Hull and East Yorkshire Hospitals NHS Trust
    Full Title: The effect of oxygen on exercise performance in chronic heart failure
    Medical condition: Chronic heart failure
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004849 10008908 Chronic heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2021-000556-19 Sponsor Protocol Number: 6011 Start Date*: 2021-10-20
    Sponsor Name:Rigshospitalet, Department of Anaesthesia, Centre of Head and Orthopaedics
    Full Title: Comparing Restrictive vs. Liberal Oxygen Strategies for Trauma Patients: The TRAUMOX2 Trial
    Medical condition: Victims of trauma are often healthy individuals prior to the incident, but acquire numerous complications including sepsis and pulmonary complications and diminished quality of life after trauma. W...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10022891 - Investigations 10033316 Oxygen saturation PT
    20.0 100000004865 10050322 Oxygen supplementation LLT
    20.0 10022891 - Investigations 10033323 Oxygen tension LLT
    20.0 10022891 - Investigations 10033324 Oxygen tension abnormal NOS LLT
    20.0 10022891 - Investigations 10033325 Oxygen tension decreased LLT
    20.0 10022891 - Investigations 10033326 Oxygen tension increased LLT
    20.0 10022891 - Investigations 10033327 Oxygen tension normal LLT
    20.1 10022891 - Investigations 10068430 Arterial oxygen saturation LLT
    20.1 10022891 - Investigations 10068431 Arterial oxygen saturation increased LLT
    20.1 10022891 - Investigations 10068432 Arterial oxygen saturation decreased LLT
    20.1 10022891 - Investigations 10068433 Arterial oxygen saturation abnormal LLT
    20.1 10022891 - Investigations 10068434 Arterial oxygen partial pressure increased LLT
    20.1 10022891 - Investigations 10068435 Arterial oxygen partial pressure decreased LLT
    20.1 10022891 - Investigations 10068436 Arterial oxygen partial pressure abnormal LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-002130-72 Sponsor Protocol Number: 8845 Start Date*: 2016-08-08
    Sponsor Name:Division of Thoracic and Hyperbaric Surgery, Medical University Graz
    Full Title: Hyperbaric Oxygenation (HBO) in traumatic spinal cord injury.
    Medical condition: We want to investigate the effect of hyperbaric oxygen therapy on the neurological and clinical outcome following traumatic injury of the spinal cord.
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2018-004679-11 Sponsor Protocol Number: 0604 Start Date*: 2020-04-21
    Sponsor Name:Division of Thoracic and Hyperbaric Surgery, Medical University Graz
    Full Title: Hyperbaric Oxygenation (HBO) in traumatic spinal cord injury - prospective study with 100 patients.
    Medical condition: We want to investigate the effect of hyperbaric oxygen therapy on the neurological and clinical outcome following traumatic injury of the spinal cord.
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2020-001457-43 Sponsor Protocol Number: APHP200388 Start Date*: 2020-04-10
    Sponsor Name:APHP
    Full Title: Dexamethasone and oxygen support strategies in ICU patients with Covid-19 pneumonia
    Medical condition: acute hypoxemic respiratory failure (AHRF)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-004209-27 Sponsor Protocol Number: 05/Q1606/127 Start Date*: 2005-11-11
    Sponsor Name:Oxford Radcliffe Hospitals NHS Trust
    Full Title: Effect of altering inspired oxygen concentrations on cerebral oxygenation during awake carotid surgery
    Medical condition: Carotid endarterectomy is an operation performed on patients with a symptomatic stenosis of the internal carotid artery. Such patients have usually presented with stroke or transient ischaemic atta...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2013-004355-20 Sponsor Protocol Number: 2013OE005B Start Date*: 2014-03-20
    Sponsor Name:Royal Brompton and Harefield NHS Foundation Trust
    Full Title: Randomised, controlled crossover trial to evaluate the Effects of Ambulatory Oxygen on health status in patients with Fibrotic Lung Disease (FLD)
    Medical condition: Fibrotic Lung Diseases (FLDs) are chronic and progressive conditions resulting in substantial morbidity and mortality. The cardinal symptom of all fibrotic Interstitial Lung Diseases (ILDs) is shor...
    Disease: Version SOC Term Classification Code Term Level
    16.1 10038738 - Respiratory, thoracic and mediastinal disorders 10022611 Interstitial lung disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2022-004166-37 Sponsor Protocol Number: 100424 Start Date*: 2023-05-02
    Sponsor Name:Division of Thoracic and Hyperbaric Surgery, Medical University Graz
    Full Title: Hyperbaric oxygenation for patients with orthostatic dysregulation (postural orthostatic tachycardia) in Long- COVID. Prospectively randomized cross- over study.
    Medical condition: Multiorgan symptoms after COVID-19 infection (Long COVID)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2019-000804-14 Sponsor Protocol Number: OPHT-070119 Start Date*: 2019-05-10
    Sponsor Name:Medical University of Vienna, Department of Clinical Pharmacology
    Full Title: The effect of hyperoxia and hypoxia on fluorescence lifetime imaging ophthalmoscopy in healthy subjects
    Medical condition: healthy volunteers
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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