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Clinical trials for Peripheral tolerance

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    125 result(s) found for: Peripheral tolerance. Displaying page 1 of 7.
    1  2  3  4  5  6  7  Next»
    EudraCT Number: 2006-005399-42 Sponsor Protocol Number: GJ001 Start Date*: 2007-04-11
    Sponsor Name:Guy's & St Thomas' NHS Foundation Trust
    Full Title: Improving symptoms of intermittent claudication in patients with erectile dysfunction and peripheral vascular disease: a pilot study assessing the benefit of daily dosing with tadalafil (Cialis) 10...
    Medical condition: Peripheral vascular disease (PVD)
    Disease: Version SOC Term Classification Code Term Level
    14.0 10047065 - Vascular disorders 10034634 Peripheral vascular disease NOS LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-012350-20 Sponsor Protocol Number: MSC-KTx Start Date*: 2008-01-14
    Sponsor Name:AZIENDA OSPEDALIERA "OSPEDALI RIUNITI DI BERGAMO" (A.O. DI RILIEVO NAZIONALE)
    Full Title: MESENCHYMAL STEM CELLS UNDER BASILIXIMAB/ LOW DOSE RATG TO INDUCE RENAL TRANSPLANT TOLERANCE
    Medical condition: Patients will be those receiving a living-related kidney transplant
    Disease: Version SOC Term Classification Code Term Level
    15.1 10021428 - Immune system disorders 10023439 Kidney transplant rejection PT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-002109-22 Sponsor Protocol Number: 02/05/Hü Start Date*: 2005-12-01
    Sponsor Name:Medical University of Vienna
    Full Title: Comparative Effects of Telmisartan and Candesartan on glucose metabolism in patients with chronic heart failure
    Medical condition: both investigated drugs are well established in the treatment of heart failure or hypertension respectively. As the investigateed Patients have this conditions according to the inclusion criteria, ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2016-003477-18 Sponsor Protocol Number: Empabrain01 Start Date*: 2017-05-04
    Sponsor Name:University Hospital Tuebingen
    Full Title: A double-blind randomized study to determine the effect of empagliflozin versus placebo on brain insulin sensitivity in patients with prediabetes
    Medical condition: brain insulin sensitivity in patients with prediabetes
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004861 10065542 Prediabetes LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-006438-33 Sponsor Protocol Number: CCB-CRC-07-02 Start Date*: 2008-06-12
    Sponsor Name:Charité - Universitätsmedizin Berlin
    Full Title: Influence of I(f) blockade on orthostatic tolerance and sympathic activity in healthy subjects.
    Medical condition: Orthostatic intolerance means the defective adaptation of the cardiovascular system to the upright position. One of the major Form of this disorder, the postural orthostatic tachycardia syndrome (o...
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-004961-25 Sponsor Protocol Number: 2008/0827 Start Date*: 2008-12-03
    Sponsor Name:CHRU de Lille
    Full Title: ETUDE COMPARATIVE KETAMINE DOSE UNIQUE VERSUS KETAMINE BOLUS ET PERFUSION CONTINUE DANS LA PRISE EN CHARGE DE L’ANALGESIE DES DOULEURS TRAUMATIQUES DES MEMBRES EN MEDECINE D’URGENCE PREHOSPITALIERE
    Medical condition: Limbs peripheral traumatisms in prehospital emergency medicine
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-004983-37 Sponsor Protocol Number: FFIS-INM-2017-04 Start Date*: 2018-10-16
    Sponsor Name:Fundación para la Formación e Investigación Sanitarias de la Región de Murcia
    Full Title: Multicenter, randomized, prospective study to establish the clinical efficacy and the mechanisms of tolerance following immunosuppression withdrawal in liver transplantation
    Medical condition: Hepatic transplant
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-007177-20 Sponsor Protocol Number: Sirolimus_Liver_Tolerance Start Date*: 2009-09-07
    Sponsor Name:Hospital Clinic Barcelona
    Full Title: EFECTO DEL SIROLIMUS SOBRE LOS BIOMARCADORES RELACIONADOS CON LA TOLERANCIA EN RECEPTORES DE TRASPLANTE HEPÁTICO ESTABLES
    Medical condition: Stable liver transplant recipients identified as non-tolerant (i.e. requiring indefinite immunosuppressive therapy) on the basis of peripheral blood transcriptional biomarkers.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10024716 Liver transplantation LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-000755-13 Sponsor Protocol Number: DACLEAN Start Date*: 2020-03-31
    Sponsor Name:CHU de Poitiers
    Full Title: ESTIMATION OF THE INCIDENCE OF COLONIZATION OF PERIPHERAL VENOUS CATHETERS AFTER SKIN DISINFECTION WITH 0.5% SODIUM HYPOCHLORITE, PRECEDED OR NOT BY AN APPLICATION OF 70% ETHANOL: PILOT, MONOCENTRI...
    Medical condition: Bacterial colonization of peripheral venous catheters
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004862 10069718 Bacterial colonization LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-001971-61 Sponsor Protocol Number: SALYCENDO Start Date*: 2016-08-29
    Sponsor Name:Radboudumc
    Full Title: The effects of acetylsalicylic acid on immunoparalysis following human endotoxemia.
    Medical condition: We will investigate the effects of acetylsalicylic acid on immunoparalysis following human endotoxemia in healthy male volunteers
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2009-015776-95 Sponsor Protocol Number: ENM-DA012 Start Date*: 2010-03-24
    Sponsor Name:Universitätsklinik für Innere Medizin, Klinische Abteilung für Endokrinologie und Nuklearmedizin
    Full Title: Effects of vitamin D supplementation in coronary artery disease patients with postchallenge hyperglycemia and vitamin D deficiency on endothelial function and insulin sensivitivity
    Medical condition: subjects with coronary artery disease, postchallenge hyperglycemia and low levels of 24-OH-vitamin D
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-005597-28 Sponsor Protocol Number: DIADEMA Start Date*: 2012-04-10
    Sponsor Name:CASA DI CURA ABANO TERME POLISPECIALISTICA E TERMALE
    Full Title: Evaluation of the Discomfort Contrast Induced during Angiographic evaluation of peripheral arterial occlusive disease to define the treatment approach for percutaneous transluminal balloon angiopla...
    Medical condition: Critical limb ischemia in diabetic patients with wounds in the foot.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10047065 - Vascular disorders 10012684 Diabetic peripheral vascular disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-001232-27 Sponsor Protocol Number: KLHExposure Start Date*: 2012-06-04
    Sponsor Name:Charité Universitaetsmedizin Berlin
    Full Title: Characterization of human peripheral and intestinal T-cell responses after mucosal antigen exposure: induction of tolerance vs. immunization by oral administration of KLH
    Medical condition: Healthy volunteers
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2017-003124-73 Sponsor Protocol Number: na Start Date*: 2018-01-31
    Sponsor Name:Maastricht University
    Full Title: Carnitine supplementation as a therapy to improve insulin sensitivity in Type 2 diabetic patients with low carnitine status
    Medical condition: Glucose tolerance
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2016-000810-31 Sponsor Protocol Number: na Start Date*: 2016-07-08
    Sponsor Name:Maastricht University
    Full Title: Impact of L-Carnitine infusion on Lipid induced Insulin resistance
    Medical condition: Glucose tolerance
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2015-000828-28 Sponsor Protocol Number: 52642 Start Date*: 2016-07-26
    Sponsor Name:UMC Utrecht
    Full Title: Titlle: Subcutaneous immunoglobulins with rHuPH20 in multifocal motor neuropathy (MMN) It is an interventional cross-over study where the use of the combination of subcutaneous immunoglobulins ...
    Medical condition: Non-inferiority and safety/tolerance of Hyqvia compared to IVIg in 20 MMN patients with at least one conduction block on EMG and stable on IVIg.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-001671-36 Sponsor Protocol Number: EC11-103 Start Date*: 2012-08-27
    Sponsor Name:Fundación para la Investigación Biomédica
    Full Title: A phase IV randomized, controlled clinical trial to compare the high flow oxygen therapy (group of intervention) opposite to the conventional oxygen therapy (group control) in patients with severe ...
    Medical condition: Severe acute respiratory failure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2020-000673-24 Sponsor Protocol Number: PHRC_N_2018_BAY Start Date*: 2021-04-15
    Sponsor Name:CHU de Clermont-Ferrand
    Full Title: Faecal microbiota transplantation for prevention of graft-versus-host sisease after allogeneic stem cell transplantation for haematological malignancies
    Medical condition: Patient who underwent Allogeneic hematopoietic stem cell transplantation (allo-HSCT) for various haematological malignancies. Faecal microbiota transplantation (FMT) will be assessed to prevent al...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2009-011003-23 Sponsor Protocol Number: GFT505-209-4 Start Date*: 2009-05-28
    Sponsor Name:GENFIT
    Full Title: A Pilot study to evaluate the Efficacy and Safety of GFT505 (80mg) orally administered once daily for 35 days in patients presenting with impaired glucose tolerance and abdominal obesity. A double ...
    Medical condition: patients presenting with impaired glucose tolerance and abdominal obesity
    Disease: Version SOC Term Classification Code Term Level
    9.1 10036481 Pre-diabetes LLT
    9.1 10059179 Abdominal obesity LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2012-000633-39 Sponsor Protocol Number: FEC-TH Start Date*: 2012-05-21
    Sponsor Name:Fundación para la Formación e Investigación Sanitaria
    Full Title: Extracorporeal photopheresis in liver transplantation. Clinical trial phase I/II safety and efficacy in patients with progressive withdrawal of immunosuppression.
    Medical condition: Liver transplantation more than 2 years of evolution to complications of immunosuppression.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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