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Clinical trials for Physiological conditions

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44336   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    113 result(s) found for: Physiological conditions. Displaying page 1 of 6.
    1  2  3  4  5  6  Next»
    EudraCT Number: 2008-003367-40 Sponsor Protocol Number: 2007/049/HP Start Date*: 2009-03-03
    Sponsor Name:CHU de Rouen
    Full Title: Pilot study of the effect of a substance P antagonist, aprepitant, on aldosterone and cortisol secretions in healthy volunteers
    Medical condition: The aim is to measure plasma aldosterone and cortisol concentrations in basal conditions and in response to different stimulation tests of the adrenal function
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-000821-30 Sponsor Protocol Number: SAD13-ER1 Start Date*: 2013-07-12
    Sponsor Name:Enrique Rey Díaz-Rubio
    Full Title: CLINICAL RESPONSE TO 5HT4 RECEPTORS AGONIST (PRUCALOPRIDE): GASTROCOLIC REFLEX
    Medical condition: chronic constipation
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-000324-19 Sponsor Protocol Number: DDDCF14 Start Date*: 2014-09-18
    Sponsor Name:KU Leuven - Drug Delivery & Disposition
    Full Title: Collection and characterization of gastrointestinal fluids in different populations and conditions
    Medical condition: healthy human volunteers (administration of a proton-pump inhibitor)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2011-006237-42 Sponsor Protocol Number: 39085 Start Date*: 2012-12-12
    Sponsor Name:Erasmus University Rotterdam
    Full Title: Optimization of exercise therapy in type 2 diabetes mellitus
    Medical condition: Insulin resistance, endothelial dysfunction, cardiovascular fitness, cardio-respiratory responses, glycemic control in deconditioned non-insulin dependent type 2 diabetes patients
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-004943-35 Sponsor Protocol Number: 5122016 Start Date*: 2017-03-01
    Sponsor Name:Radboud University Medical Center
    Full Title: Stimulation of ADH independent urine concentration in healthy volunteers
    Medical condition: healthy volunteers; the information of this pilot study will be used in the care of patients with diabetes insipidus
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-002602-39 Sponsor Protocol Number: 1562016 Start Date*: 2016-10-25
    Sponsor Name:Radboud University Medical Center
    Full Title: FGF23 response in hypophosphatemia
    Medical condition: healthy volunteers the information of this pilot study will be used in the care of patients with hypophosphatemia due to renal phosphate wasting
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-002239-33 Sponsor Protocol Number: CRHMOT2014 Start Date*: 2014-10-14
    Sponsor Name:TARGID, KU Leuven
    Full Title: The effect of corticotrophin-releasing hormone (CRH) on esophageal motility in healthy volunteers
    Medical condition: Changes in esophageal motility induced by CRH-administration
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2015-002703-28 Sponsor Protocol Number: DDD15POSA Start Date*: 2015-08-06
    Sponsor Name:KU Leuven - Drug Delivery & Disposition
    Full Title: Gastrointestinal Behavior of Posaconazole in Healthy Volunteers
    Medical condition: • Administering one tablet of Noxafil with a glass of 240 ml of water • Administering four tablets of Noxafil with a glass of 240 ml of water • Administering one tablet of Noxafil with a glass of 2...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2005-000434-21 Sponsor Protocol Number: LP1 Start Date*: 2005-06-15
    Sponsor Name:Kognitive Neurologie, Institut für Medizin, Forschungszentrum Jülich
    Full Title: Neurochemische Modulation von Exekutiv- und Gedächtnisfunktionen
    Medical condition: Progressive cognitive decline in physiological aging
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-001683-22 Sponsor Protocol Number: 1/2011AITT Start Date*: 2011-06-10
    Sponsor Name:University of Debrecen, Medical and Health Science Center, Department of Anaesthesiology and Intensive Therapy
    Full Title: Reversal of residual rocuronium neuromuscular block using sugammadex: a prospective, dobule-blind, randomized, controlled, dose-finding study
    Medical condition: The effect of sugammadex dose on residual neuromuscular blockade will be investigated, therefore patients suffering from various conditions undergoing surgery in general anaesthesia with muscle rel...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-004666-34 Sponsor Protocol Number: AITT2014/1 Start Date*: 2014-03-17
    Sponsor Name:University of Debrecen, Medical and Health Science Center, Department of Anaesthesiology and Intensive Therapy
    Full Title: Reversal of vecuronium induced residual neuromuscular block using sugammadex: a prospective, dobule-blind, randomized, controlled, dosefinding study
    Medical condition: The effect of sugammadex dose on residual neuromuscular blockade will be investigated, therefore patients suffering from various conditions undergoing surgery in general anaesthesia with muscle rel...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-004766-15 Sponsor Protocol Number: MK-0518B-254 Start Date*: 2015-05-04
    Sponsor Name:Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc.
    Full Title: MK-518B Food Effect Study
    Medical condition: N/A
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2013-002214-13 Sponsor Protocol Number: IIBSP-OXI-2013-62 Start Date*: 2013-10-28
    Sponsor Name:Institut de Recerca de l?Hospital de la Santa Creu i Sant Pau ? IIB Sant Pau
    Full Title: Evaluation of oxidative stress associated with the administration of two different concentrations of oxygen for the maintenance of general anesthesia
    Medical condition: General anesthesia and oxidative stress
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-003104-20 Sponsor Protocol Number: Rimona2011 Start Date*: 2011-10-06
    Sponsor Name:UZLeuven
    Full Title: The effect of Acomplia® (rimonabant) on esophageal sensitivity and gastric accommodation during food intake in healthy volunteers: a single-blind, placebo-controlled study
    Medical condition: study is conducted on healthy volunteers, no medical condition is investigated
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2008-003623-23 Sponsor Protocol Number: can.clo.ris.fMRI Start Date*: 2008-09-17
    Sponsor Name:Academisch medisch centrum, department of psychiatry
    Full Title: Effect of different antipsychotic medication on craving related brain activity in patients with schizophrenia and cannabis abuse or dependence: a randomized controlled study comparing clozapine and...
    Medical condition: A randomized controlled trial comparing the effect of clozapine and risperidone on cannabis craving in cannabis abusing or dependent patients with schizophrenia. Specific cognitive tasks will be us...
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-001009-26 Sponsor Protocol Number: DDD19GISAM Start Date*: 2019-09-10
    Sponsor Name:KU Leuven - Drug Delivery and Disposition
    Full Title: Gastrointestinal behaviour of mesalazine in healthy volunteers
    Medical condition: Healthy volunteers
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2019-000958-56 Sponsor Protocol Number: 2019/375 Start Date*: 2019-08-16
    Sponsor Name:Helse Fonna
    Full Title: “Haemodynamic stability during induction of general anesthesia with propofol and remifentanil: A randomized, controlled, double-blind study comparing low vs high propofol doses.”
    Medical condition: In daily clinical work we observe a hypotensive effect and a reduction in HR when induction of general anesthesia is performed using propofol and remifentanil. It is difficult to differentiate the ...
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-002094-22 Sponsor Protocol Number: 2013MM002B Start Date*: 2013-08-29
    Sponsor Name:Royal Brompton and Harefield NHS Foundation Trust (RB&HFT)
    Full Title: Comparison of ultra-low-dose Oral versus Transdermal Hormone Therapy on coagulation activation and metabolic risk factors for Cardiovascular Disease
    Medical condition: The effect of oestrogen replacement therapy taken either orally or transdermally and observing any likely benefit of both these therapies on the risks Venous thromobembolic events and cardiovascul...
    Disease: Version SOC Term Classification Code Term Level
    16.1 10038604 - Reproductive system and breast disorders 10027309 Menopause and related conditions HLGT
    Population Age: Adults Gender: Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2012-000259-14 Sponsor Protocol Number: 1/2012AITT Start Date*: 2012-08-31
    Sponsor Name:University of Debrecen, Medical and Health Science Center, Department of Anaesthesiology and Intensive Therapy
    Full Title: Reversal of residual pipecuronium neuromuscular block using sugammadex: a randomized, double-blind, placebo controlled, dosefinding study
    Medical condition: The effect of sugammadex dose on residual neuromuscular blockade will be investigated, therefore patients suffering from various conditions undergoing surgery in general anaesthesia with muscle rel...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-002019-13 Sponsor Protocol Number: 2015/3AITT Start Date*: 2015-10-12
    Sponsor Name:University of Debrecen, Medical and Health Science Center, Department of Anaesthesiology and Intensive Therapy
    Full Title: Reversal of deep pipecuronium neuromuscular block using sugammadex: a randomized, double-blind, dosefinding study
    Medical condition: The effect of sugammadex dose on deep neuromuscular blockade will be investigated, therefore patients suffering from various conditions undergoing surgery in general anaesthesia with muscle relax...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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