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Clinical trials for Propofol

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   43871   clinical trials with a EudraCT protocol, of which   7290   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    240 result(s) found for: Propofol. Displaying page 1 of 12.
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    EudraCT Number: 2005-005400-17 Sponsor Protocol Number: 2005-087 Start Date*: 2005-12-15
    Sponsor Name:Dept. of Anaesthesia, Center of Head and Orthopaedics, Copenhagen University Hospital Rigshospitalet
    Full Title: Optimizing propofol in obese patients
    Medical condition: Depth of anesthesia during hysterescomia in propofol/remifentanil anaesthesia
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2015-000537-69 Sponsor Protocol Number: PROP2% Start Date*: 2015-09-21
    Sponsor Name:Universitair Ziekenhuis Brussel
    Full Title: Real time monitoring of blood propofol concentration
    Medical condition: - General anaesthesia - Pharmacokinetics and Pharmacodynamics of Propofol - Inflammatory parameters - Elective thyroid, oncologic breast,ENT or cervical arthrodesis surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-004551-67 Sponsor Protocol Number: SED001 Start Date*: 2017-04-18
    Sponsor Name:Sedana Medical AB
    Full Title: A randomised, controlled, open-label study to confirm the efficacy and safety of sedation with isoflurane in invasively ventilated ICU patients using the AnaConDa administration system
    Medical condition: Adult subjects admitted to the ICU clinically indicated to require sedation with propofol and invasive ventilation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) SI (Completed)
    Trial results: View results
    EudraCT Number: 2019-000958-56 Sponsor Protocol Number: 2019/375 Start Date*: 2019-08-16
    Sponsor Name:Helse Fonna
    Full Title: “Haemodynamic stability during induction of general anesthesia with propofol and remifentanil: A randomized, controlled, double-blind study comparing low vs high propofol doses.”
    Medical condition: In daily clinical work we observe a hypotensive effect and a reduction in HR when induction of general anesthesia is performed using propofol and remifentanil. It is difficult to differentiate the ...
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NO (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-002323-28 Sponsor Protocol Number: prop01 Start Date*: 2016-06-28
    Sponsor Name:Universitair Ziekenhuis Brussel
    Full Title: Blood concentration and pharmacokinetic analysis of propofol following administration of single induction dose in small children
    Medical condition: Children scheduled for elective surgery
    Disease:
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: BE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-001373-33 Sponsor Protocol Number: 2016-3 Start Date*: 2017-02-17
    Sponsor Name:Region Ostergotland
    Full Title: Clinical Study Protocol An open phase IV,RCT, evaluating patient controlled sedation, in three different dosages of propofol in healthy subjects undergoing elective gynaecological out-patient su...
    Medical condition: Gynecological outpatient surgery
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-001770-15 Sponsor Protocol Number: 1418 Start Date*: 2020-01-24
    Sponsor Name:Complejo Asistencial Universitario de León
    Full Title: Analysis of the effectiveness of Non-painful Endovenous Management (MENA) in the administration of Propofol
    Medical condition: Propofol is used as an intravenous agent for induction and anesthetic maintenance. However, without any intervention before your administration, as is usually administered, the incidence of local p...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-002780-14 Sponsor Protocol Number: Asena/Prop-01 Start Date*: 2007-07-16
    Sponsor Name:Hospital General Universitario Alicante, Dpto Farmacologia Clinica
    Full Title: Estudio comparativo de la eficacia de la bomba de jeringa Alaris® (Asena®) de uso polivalente en la administración de tres formulaciones de propofol
    Medical condition: inducción anestésica en pacientes que requieren cirugía CLASS ASA I y II
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-003909-26 Sponsor Protocol Number: BOP-TCI-001 Start Date*: 2014-02-04
    Sponsor Name:UMCG
    Full Title: Bayesian optimized Propofol Target-Controlled Infusion
    Medical condition: Patients requiring general anaesthesia for surgery using propofol and requiring an arterial line for invasive blood pressure monitoring as part of their clinical care.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-003571-39 Sponsor Protocol Number: HC-G-H-0705 Start Date*: 2008-04-23
    Sponsor Name:B. Braun Melsungen AG
    Full Title: Prospective, monocentric, controlled, randomized, double-blind study to compare two different propofol emulsions regarding tolerability and injection pain during the induction of anesthesia in adults
    Medical condition: reduction of injection pain during induction of anaesthesia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2010-018233-21 Sponsor Protocol Number: WEC 0910 Start Date*: 2010-03-31
    Sponsor Name:Leiden University Medical Centre
    Full Title: Modeling the respiratory effects of subanesthetic doses of propofol under closed-loop or non-steady-state conditions without and with a remifentanil background infusion in healthy volunteers.
    Medical condition: This study is performed in healthy volunteers. The study is aimed at investigating the effect of propofol and remifentanil-propofol interaction on breathing in awake, non-artificially ventilated vo...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-000022-29 Sponsor Protocol Number: 013/2011 Start Date*: 2011-09-21
    Sponsor Name:Medizinische Universität Wien
    Full Title: The interaction of intravenous lidocaine on the Cp50 of propofol for skin incision
    Medical condition: the effects of intravenous application of lidocaine on the Cp50 during propofol narcosis should be investigated
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2012-002533-10 Sponsor Protocol Number: SuRe-001 Start Date*: 2013-05-22
    Sponsor Name:UMCG
    Full Title: Comparison of the effects of atropine on haemodynamics and tissue oxygenation in anaesthesia with propofol and sufentanil versus propofol and remifentanil’
    Medical condition: Comparison of the effects of atropine on haemodynamics and tissue oxygenation in anaesthesia with propofol and sufentanil versus propofol and remifentanil
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-000964-33 Sponsor Protocol Number: Feline02 Start Date*: 2015-09-17
    Sponsor Name:Erasmus Medical Center, Department of Anesthesiology
    Full Title: Dexmedetomidine versus propofol in awake implantation of a neuromodulative system.
    Medical condition: Awake implantation of a neuromodulative system.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2009-010614-30 Sponsor Protocol Number: CH/2007/2746 Start Date*: 2009-05-08
    Sponsor Name:University Hospitals Bristol
    Full Title: Randomised cross-over pilot study to determine the effects of isoflurane and propofol on pulmonary vascular resistance in children with pulmoanry hypertension
    Medical condition: children with pulmonary hypertension
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2012-000584-25 Sponsor Protocol Number: FLAM01 Start Date*: 2012-03-29
    Sponsor Name:UZBrussel
    Full Title: Propofol and etomidate. Are they also safe for patients with Brugada-Syndrome?
    Medical condition: Patients suspected to have Brugada Syndrome
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2009-017921-20 Sponsor Protocol Number: none Start Date*: 2010-09-16
    Sponsor Name:Univ. Klinik für Anästhesiologie
    Full Title: Influence of Gender on the Plasma-Effect site equilibration time of propofol anesthetic and Cisatracurium Besylate neuromuscular blocking agent. A pilot study.
    Medical condition: effect of Gender on Pharmacokinetics of Propofol and cisatracurium
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2022-003737-19 Sponsor Protocol Number: CHUB-ITF-sevo-propofol Start Date*: 2023-01-10
    Sponsor Name:CHU Brugmann
    Full Title: Influence of sevoflurane and propofol on maximum muscular strength, speed of contraction and relaxation, in humans: A pilot study.
    Medical condition: Impact of anesthetic drugs on neuromuscular transmission
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-000071-90 Sponsor Protocol Number: AGO/2017/002 Start Date*: 2017-03-15
    Sponsor Name:Ghent University Hospital
    Full Title: Effect of sevoflurane and propofol on hepato-splanchnic pressure and flow during hepatobiliary surgery.
    Medical condition: patients scheduled for hepato-biliary surgery.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2016-004455-78 Sponsor Protocol Number: SINUS Start Date*: 2017-06-09
    Sponsor Name:Region Östergötland
    Full Title: Sedation with propofol and remifentanil during ventricular tachycardia treatment: patient-controlled versus nurse anesthetists controlled - a randomized controlled trial
    Medical condition: Percutaneous pericardial access for mapping and ablation of ventricular tachycardia
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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