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Clinical trials for Sinusitis

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   43881   clinical trials with a EudraCT protocol, of which   7295   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    76 result(s) found for: Sinusitis. Displaying page 1 of 4.
    1  2  3  4  Next»
    EudraCT Number: 2010-022188-37 Sponsor Protocol Number: 29072010 Start Date*: 2010-11-29
    Sponsor Name:Pirkanmaan sairaanhoitopiiri
    Full Title: A comparative study between the Relieva Stratus MicroFlow Spacer drug eluting ethmoid sinus stent therapy and the intranasal corticoid steroid therapy in the treatment of patients with chronic rhin...
    Medical condition: Kaikki tutkittavat henkilöt niin lääkeimplantti- kuin nenäsumuteverrokkiryhmässä sairastavat kroonista sinuiittia
    Disease: Version SOC Term Classification Code Term Level
    12.1 10031748 Other chronic sinusitis LLT
    12.1 10040755 Sinusitis chronic NOS LLT
    12.1 10009137 Chronic sinusitis PT
    12.1 10008871 Chronic ethmoidal sinusitis LLT
    12.1 10008877 Chronic frontal sinusitis LLT
    12.1 10008998 Chronic maxillary sinusitis LLT
    12.1 10009137 Chronic sinusitis LLT
    12.1 10009138 Chronic sinusitis, ethmoidal LLT
    12.1 10009139 Chronic sinusitis, other LLT
    12.1 10009140 Chronic sinusitis, sphenoidal LLT
    12.1 10009141 Chronic sinusitis, unspecified LLT
    12.1 10009145 Chronic sphenoidal sinusitis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-001100-11 Sponsor Protocol Number: 14/0644 Start Date*: 2018-07-13
    Sponsor Name:University College London
    Full Title: Defining best Management in Adult Chronic RhinOsinusitis
    Medical condition: Chronic rhinosinusitis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10052106 Rhinosinusitis LLT
    20.1 10021881 - Infections and infestations 10009137 Chronic sinusitis PT
    20.1 10021881 - Infections and infestations 10009137 Chronic sinusitis PT
    20.1 10021881 - Infections and infestations 10009141 Chronic sinusitis, unspecified LLT
    20.0 10021881 - Infections and infestations 10031748 Other chronic sinusitis LLT
    20.1 10021881 - Infections and infestations 10009138 Chronic sinusitis, ethmoidal LLT
    20.0 10021881 - Infections and infestations 10009139 Chronic sinusitis, other LLT
    20.1 10021881 - Infections and infestations 10009140 Chronic sinusitis, sphenoidal LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2007-003739-22 Sponsor Protocol Number: GAL-01-2007 Start Date*: 2007-10-04
    Sponsor Name:GALSOR S.R.L.
    Full Title: Safety and efficacy (for the symptom remission) of the treatment adjuvant of the antibiotic therapy of the acute episode of sinusitis (acute, subacute, chronic)with Ecballium Elaterium (SINUclean D...
    Medical condition: Acute sinusitis or exacerbation of subacute or chronic sinusitis.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10040753 Sinusitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-005828-84 Sponsor Protocol Number: ECP Start Date*: 2009-04-02
    Sponsor Name:ENT Hospital, Johannes-Gutenberg University, Mainz
    Full Title: Inflammatory mediators in nasal discharge of chronic rhinosinusitis patients treated with erythromycin.
    Medical condition: Effect of erythromycin therapy on the inflammatory mediators in nasal discharge of chronic rhinosinusitis patients.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10009137 Chronic sinusitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-002779-34 Sponsor Protocol Number: BAY 12-8039/11881 Start Date*: 2005-12-13
    Sponsor Name:BAYER
    Full Title: Prospective, multicenter, randomized, double blind, parallel arm study to evaluate the efficacy and safety of Moxifloxacin 400 mg OD for 7 days versus amoxicillin clavulanate/claritromycin for 10 d...
    Medical condition: Acute bacterial rhinosinusitis
    Disease: Version SOC Term Classification Code Term Level
    6.1 10001076 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2021-005906-83 Sponsor Protocol Number: LYR-210-2021-004 Start Date*: 2022-08-05
    Sponsor Name:Lyra Therapeutics, Inc.
    Full Title: ENLIGHTEN 1: A Phase III, Randomized, Blinded, Controlled, Parallel-Group Trial to Evaluate the Efficacy and Safety of LYR-210 for the Treatment of Chronic Rhinosinusitis (CRS) in Adults
    Medical condition: Chronic Rhinosinusitis (CRS) in Adults
    Disease: Version SOC Term Classification Code Term Level
    20.1 10021881 - Infections and infestations 10009137 Chronic sinusitis PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: CZ (Ongoing) ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-001460-42 Sponsor Protocol Number: HMR 3647A/4023 Start Date*: 2004-11-16
    Sponsor Name:Aventis Intercontinental - Sanofi-aventis
    Full Title: A prospective, randomized, open-label, active-controlled study in adult subjects with acute bacterial sinusitis comparing the clinical efficacy of telithromycin (KETEK®) 800 mg once a day for 5 da...
    Medical condition: acute bacterial sinusitis (ABS)
    Disease: Version SOC Term Classification Code Term Level
    7.0 10000858 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2015-002102-37 Sponsor Protocol Number: ORL-CENS-2015 Start Date*: 2015-10-02
    Sponsor Name:Fundació Parc Taulí
    Full Title: Open randomized clinical trial to compare the efficacy of hypotensive anesthesia with clonidine or dexmedetomidine during endoscopic nasal surgery
    Medical condition: Nasosinusal endoscopic surgery in patients with chronic sinusitis and/or nasal polyposis
    Disease: Version SOC Term Classification Code Term Level
    18.0 10021881 - Infections and infestations 10009137 Chronic sinusitis PT
    18.0 10042613 - Surgical and medical procedures 10028755 Nasal polypectomy PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-006911-27 Sponsor Protocol Number: LYR-210-2021-005 Start Date*: 2022-07-28
    Sponsor Name:Lyra Therapeutics, Inc.
    Full Title: ENLIGHTEN 2: A Phase III, Randomized, Blinded, Controlled, Parallel-Group Trial to Evaluate the Efficacy and Safety of LYR-210 for the Treatment of Chronic Rhinosinusitis (CRS) in Adults
    Medical condition: Chronic Rhinosinusitis (CRS) in Adults
    Disease: Version SOC Term Classification Code Term Level
    20.1 10021881 - Infections and infestations 10009137 Chronic sinusitis PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: HU (Ongoing) DE (Trial now transitioned) BG (Trial now transitioned) BE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-004621-89 Sponsor Protocol Number: LYR-210-2018-002 Start Date*: 2019-07-29
    Sponsor Name:Lyra Therapeutics, Inc.
    Full Title: A Phase II, Randomized, Blinded, Sham Procedure-Controlled, Parallel-Group Trial to Evaluate the Efficacy, Safety and Tolerability of LYR-210 in Adult Subjects with Chronic Sinusitis (LANTERN Study)
    Medical condition: Chronic sinusitis
    Disease: Version SOC Term Classification Code Term Level
    20.1 10021881 - Infections and infestations 10009137 Chronic sinusitis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) AT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-001435-63 Sponsor Protocol Number: NACFL-ZI-L-01-06 Start Date*: 2008-01-28
    Sponsor Name:ZAMBON ITALIA
    Full Title: AEROSOLIC TREATMENT OF ACUTE AND RECURRENT RHINOSINUSITIS DURING INTERCRITICAL STAGES : SINGLE BLIND CLINICAL STUDY, N-ACETYLCISTEIN VS AMBROXOL, ASSOCIATED WITH CORTISONE THERAPY
    Medical condition: Patients with acute recurrent rhinosinusitis(intercritical stages)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10001076 Acute sinusitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2011-005965-18 Sponsor Protocol Number: ORL-CENS-2012 Start Date*: 2012-02-21
    Sponsor Name:Fundació Parc Taulí
    Full Title: Open randomized trial to compare the bleeding during endoscopic nasal surgery after hypotensive anesthesia with clonidine or remifentanil.
    Medical condition: Nasosinusal endoscopic surgery in patients with chronic sinusitis and/or nasal polyposis
    Disease: Version SOC Term Classification Code Term Level
    14.1 10038738 - Respiratory, thoracic and mediastinal disorders 10028756 Nasal polyps PT
    14.1 10042613 - Surgical and medical procedures 10052967 Nasopharyngeal surgery PT
    14.1 10021881 - Infections and infestations 10009137 Chronic sinusitis PT
    14.1 10038738 - Respiratory, thoracic and mediastinal disorders 10040749 Sinus polyp PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-003117-35 Sponsor Protocol Number: EFC16723 Start Date*: 2021-03-17
    Sponsor Name:Sanofi-aventis Recherche & Développement
    Full Title: A randomized, double-blind, placebo-controlled, 2-part study to evaluate the efficacy and safety of dupilumab in patients with uncontrolled, chronic rhinosinusitis without nasal polyposis (CRSsNP)
    Medical condition: Chronic rhinosinusitis without nasal polyposis
    Disease: Version SOC Term Classification Code Term Level
    20.1 10021881 - Infections and infestations 10009137 Chronic sinusitis PT
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: BE (Completed) PT (Completed) SE (Completed) HU (Ongoing) PL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2006-006220-19 Sponsor Protocol Number: SUM-2006/01-INT Start Date*: 2008-11-27
    Sponsor Name:PLIVA Hrvatska d.o.o.
    Full Title: Safety and Efficacy of Sumamed® Therapy in the Treatment of Respiratory Tract Infections in Adults and Children: International, Multicenter, Non-Comparative Study
    Medical condition: acute pharyngitis/tonsilitis acute sinusitis acute otitis media acute exacerbation of chronic bronchitis community acquired pneumonia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10001002 Acute pharyngitis LLT
    9.1 10001093 Acute tonsillitis LLT
    9.1 10001076 Acute sinusitis LLT
    9.1 10033079 Otitis media acute LLT
    9.1 10000743 Acute exacerbation of chronic bronchitis LLT
    9.1 10010120 Community acquired pneumonia LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: SI (Completed) CZ (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-000648-86 Sponsor Protocol Number: OPN-FLU-CS-3206 Start Date*: 2019-10-01
    Sponsor Name:OptiNose US, Inc.
    Full Title: A 24-Week Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter Study Evaluating the Efficacy and Safety of Intranasal Administration of 186 and 372 μg of OPN-375 Twice a Day (B...
    Medical condition: Chronic rhinosinusitis
    Disease: Version SOC Term Classification Code Term Level
    20.1 10021881 - Infections and infestations 10009137 Chronic sinusitis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) CZ (Completed) PL (Completed) ES (Ongoing) BG (Completed) RO (Ongoing)
    Trial results: View results
    EudraCT Number: 2005-000639-13 Sponsor Protocol Number: A0661142 Start Date*: 2005-10-10
    Sponsor Name:Pfizer Ltd
    Full Title: An open-label, multi-center trial of azithromycin pharmacokinetics in sinus aspirate and serum following oral administration of either a 500 mg immediate-release (IR) once-daily 3 day regimen or a ...
    Medical condition: Acute bacterial sinusitis
    Disease: Version SOC Term Classification Code Term Level
    7.1 10060841 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Prematurely Ended) SE (Prematurely Ended) DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2019-000368-12 Sponsor Protocol Number: OPN-FLU-CS-3205 Start Date*: 2019-10-01
    Sponsor Name:OptiNose US, Inc.
    Full Title: A 24-Week Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter Study Evaluating the Efficacy and Safety of Intranasal Administration of 186 and 372 μg of OPN-375 Twice a Day (...
    Medical condition: Chronic sinusitis
    Disease: Version SOC Term Classification Code Term Level
    20.1 10021881 - Infections and infestations 10009137 Chronic sinusitis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) BG (Completed)
    Trial results: View results
    EudraCT Number: 2005-005654-53 Sponsor Protocol Number: BroSin 05 Start Date*: 2006-12-07
    Sponsor Name:Ursapharm Arzneimittel GmbH & Co. KG
    Full Title: "Explorative triple-arm dosis-finding study for examination about the effectivity and tolerance of Bromelain by acute sinusitis"
    Medical condition: Therapy of acute sinusitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-001837-16 Sponsor Protocol Number: 027SC05134 Start Date*: 2006-05-16
    Sponsor Name:ANGELINI
    Full Title: PRULIFLOXACIN VERSUS LEVOFLOXACIN IN PATIENTS WITH ACUTE BACTERIAL RHINOSINUSITIS ABRS
    Medical condition: ACUTE BACTERIAL RHINOSINUSITIS
    Disease: Version SOC Term Classification Code Term Level
    6.1 10001076 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed) HU (Completed) AT (Completed) ES (Completed) RO (Completed)
    Trial results: View results
    EudraCT Number: 2014-004925-42 Sponsor Protocol Number: P04824 Start Date*: 2015-04-13
    Sponsor Name:Schering-Plough Research Institute, a Division of Schering Corporation
    Full Title: Efficacy and Safety of 200 mcg BID Mometasone Furoate Nasal Spray (MFNS) vs Placebo as Adjunctive Treatment to Antibiotics in Relief of Symptoms of Acute Bacterial Sinusitis
    Medical condition: Acute Bacterial Sinusitis
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
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