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Clinical trials for Sodium channels

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44336   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    9 result(s) found for: Sodium channels. Displaying page 1 of 1.
    EudraCT Number: 2012-003815-71 Sponsor Protocol Number: AK-1-2012 Start Date*: 2013-02-08
    Sponsor Name:Department of Medical Research
    Full Title: The effect of furosemide on fluid volumes and biomarkers in urine for measurement of sodium and water channel activity in healthy subjects
    Medical condition: healthy people
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004848 10049506 Investigation NOS LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-002585-23 Sponsor Protocol Number: ANJ-02-2015 Start Date*: 2016-01-08
    Sponsor Name:Medicinsk Forskningsafsnit, Regionshospitalet Holstebro (Department of Medical Research, Regional Hospital Holstebro)
    Full Title: The effect of 3% NaCl and furosemid on biomarkers and the kidneys managment of sodium and water, vasoactive hormones and GFR in healthy subjects.
    Medical condition: Healthy volunteers (The effect of flurosemide, together with an infusion of hypertone saline, on the kidneys, using biomarkers)
    Disease: Version SOC Term Classification Code Term Level
    18.1 10022891 - Investigations 10022891 Investigations SOC
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-001169-33 Sponsor Protocol Number: SAFA-1-2012 Start Date*: 2012-07-02
    Sponsor Name:Department of Medical Research
    Full Title: Effects of tolvaptan on renal sodium and water handling and circulation during inhibition of the nitric oxide system in healthy subjects
    Medical condition: SIADH (Syndrome of inappropriate ADH production) Overhydration Hyponatrimia
    Disease: Version SOC Term Classification Code Term Level
    14.1 10027433 - Metabolism and nutrition disorders 10021038 Hyponatremia LLT
    14.1 10014698 - Endocrine disorders 10040626 SIADH LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-001131-31 Sponsor Protocol Number: FHC-1-2012 Start Date*: 2012-06-14
    Sponsor Name:Department of Medical Research
    Full Title: Effekts of nebivolol on the nitric oxide system in patients with essentiel hypertension
    Medical condition: Essential Hypertension
    Disease: Version SOC Term Classification Code Term Level
    14.1 10047065 - Vascular disorders 10015488 Essential hypertension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-003407-17 Sponsor Protocol Number: CLD-1-2021 Start Date*: 2022-04-19
    Sponsor Name:University Clinic of Nephrology and Hypertension
    Full Title: Combined effects of potassium, nitrate and sodium on blood pressure in patients with hypertension
    Medical condition: Essential Hypertension
    Disease: Version SOC Term Classification Code Term Level
    20.0 10047065 - Vascular disorders 10020772 Hypertension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-003309-24 Sponsor Protocol Number: 2013-562 Start Date*: 2013-10-28
    Sponsor Name:Grete Andersen
    Full Title: Lamotrigine as treatment of Myotonia
    Medical condition: Myotonia is a symptom seen certain inherited muscle dystrophies and pure channelopathies (Dystrophia myotonica type 1 and 2, Myotonia Congenita, Paramyotonia Congenita, Hyperkalæmisk periodic paral...
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029205 - Nervous system disorders 10061533 Myotonia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2013-000407-16 Sponsor Protocol Number: 2197944/202 Start Date*: 2013-07-24
    Sponsor Name:Convergence Pharmaceuticals Ltd
    Full Title: A randomised three week double-blind crossover study to compare the efficacy and safety of CNV2197944 75 mg tid versus placebo in the treatment of neuropathic pain in patients with diabetic periphe...
    Medical condition: Neuropathic pain associated with diabetic peripheral neuropathy
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004852 10067547 Diabetic peripheral neuropathic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) HU (Completed) BG (Completed) PL (Completed)
    Trial results: Removed from public view
    EudraCT Number: 2005-003894-26 Sponsor Protocol Number: 1160.26 Start Date*: 2005-12-23
    Sponsor Name:Boehringer Ingelheim AB
    Full Title: Randomized Evaluation of Long term anticoagulant therapy (RE-LY) comparing the efficacy and safety of two blinded doses of dabigatran etexilate with open label warfarin for the prevention of stroke...
    Medical condition: Prevention of Stroke and Systemic Embolism in patients with Atrial Fibrillation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) DK (Completed) FI (Completed) CZ (Completed) AT (Completed) HU (Completed) DE (Completed) SK (Completed) IT (Completed) ES (Completed) GB (Completed) PT (Completed) GR (Completed)
    Trial results: View results
    EudraCT Number: 2010-023963-16 Sponsor Protocol Number: 1014802/202 Start Date*: 2012-01-05
    Sponsor Name:Convergence Pharmaceuticals Ltd
    Full Title: A Placebo-Controlled, Double-Blind Randomized Withdrawal Study to Evaluate the Safety and Efficacy of CNV1014802 in Patients with Trigeminal Neuragia
    Medical condition: Trigeminal neuralgia
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004852 10029227 Neuralgia trigeminal LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) DE (Completed) DK (Completed) IT (Completed) ES (Completed) LV (Completed) LT (Completed) EE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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