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Clinical trials for Top surgery

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    32 result(s) found for: Top surgery. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2014-005702-37 Sponsor Protocol Number: TISKids Start Date*: 2015-04-08
    Sponsor Name:Erasmus Medical Center
    Full Title: Top-Down Infliximab Study in Kids with Crohn's disease (TISKids)
    Medical condition: Crohn's disease
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-000333-36 Sponsor Protocol Number: 17012006 Start Date*: 2006-04-26
    Sponsor Name:Hull & East Yorkhire NHS Hospitals Trust
    Full Title: A randomised comparison of 0.5% levobupivacaine with a lidocaine/epinephrine/ fentanyl mixture for epidural top up for emergency caesarean section after “low dose” epidural for labour
    Medical condition: pregnant women, in labour requiring emergency caesarean section under epidural anaesthesia
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2021-004034-11 Sponsor Protocol Number: GR-OG-279239-04 Start Date*: 2022-05-18
    Sponsor Name:Genera Research Ltd
    Full Title: A randomized, evaluator-blinded, dose-ranging, proof of concept study of efficacy, safety and tolerability of Osteogrow-C (rhBMP6 delivered in autologous blood coagulum [ABC] supplemented with sy...
    Medical condition: The treatment of non-union of the tibia
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10042613 Surgical and medical procedures SOC
    21.0 10028395 - Musculoskeletal and connective tissue disorders 10017088 Fracture nonunion PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-012847-40 Sponsor Protocol Number: Pergoveris_Cetrorelix_1 Start Date*: 2009-11-11
    Sponsor Name:NHS Lothian [...]
    1. NHS Lothian
    2. The University of Edinburgh
    Full Title: A Randomised Study Comparing Two Different Regimens of Ovarian Stimulation Using Pergoveris and Cetrorelix for Controlled Ovarian Superovulation in Assisted Conception Treatment.
    Medical condition: Subfertility
    Disease: Version SOC Term Classification Code Term Level
    12. 10042391 Subfertility LLT
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2017-004684-12 Sponsor Protocol Number: iNO_Protocol_V1.1_16.07.17 Start Date*: 2019-05-16
    Sponsor Name:Lady Cilento Children's Hospital
    Full Title: Nitric Oxide during Cardio Pulmonary Bypass during surgery for congenital heart defects: A Randomised Controlled Trial.
    Medical condition: Congenital heart disease ranks still within the top causes of infant mortality in industrialized countries. Despite considerable advances over the past decade, the exposure to cardiopulmonary bypas...
    Disease:
    Population Age: Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-000645-13 Sponsor Protocol Number: ITSKids Start Date*: 2012-10-17
    Sponsor Name:ErasmusMC
    Full Title: Infliximab Top-down Study in Kids with Crohn’s disease
    Medical condition: Crohn's disease
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing) BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-006143-26 Sponsor Protocol Number: 2019/ABM/01/00062 Start Date*: 2021-05-02
    Sponsor Name:Śląski Uniwersytet Medyczny w Katowicach
    Full Title: A Single center, Open-Label, Randomized Study to Evaluate the Safety and Efficacy of neoadjuvant and adjuvant Pembrolizumab on top of standard Chemo-Radiotherapy (Stupp protocol) in Treatment of Pa...
    Medical condition: Glioblastoma Multiforme
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10018337 Glioblastoma multiforme PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2010-021783-15 Sponsor Protocol Number: Version 1.0 Start Date*: 2010-12-31
    Sponsor Name:Guys and St Thomas' NHS Foundation Trust
    Full Title: Ropivacaine 0.75% versus Levobupivacaine 0.5% for conversion of labour epidural to surgical anaesthesia for emergency Caesarean section. (RoLe Trial)
    Medical condition: Conversion of labour epidural to surgical anaesthesia for emergency Caesarean section
    Disease: Version SOC Term Classification Code Term Level
    12.1 10006924 Caesarean section LLT
    12.1 10054375 Epidural anesthesia LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2016-000686-23 Sponsor Protocol Number: RAVE_v1 Start Date*: 2017-03-29
    Sponsor Name:Erasmus MC
    Full Title: The Rotterdam Antiplatelet Therapy in Vascular Patients Study
    Medical condition: myocardial injury in patients undergoing major vascular surgery, leading to (spontaneous) acute coronary syndrome and death through intracoronary plaque damage and subsequent thrombosis after major...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2013-003323-11 Sponsor Protocol Number: ITIBU001 Start Date*: 2014-10-01
    Sponsor Name:"Sapienza" University of Rome
    Full Title: RANDOMIZED CLINICAL TRIAL, PLACEBO-CONTROLLED, SPLIT-MOUTH, A DOUBLE-BLIND, FOR THE EVALUATION OF THE EFFECTIVENESS OF PREemptive ANALGESIA BY ADMINISTRATION OF IBUPROFEN 400MG, FOR THE CONTROL ...
    Medical condition: POST-OPERATIVE ACUTE PAIN (DAPO)
    Disease: Version SOC Term Classification Code Term Level
    17.1 10017947 - Gastrointestinal disorders 10031009 Oral pain PT
    17.1 10017947 - Gastrointestinal disorders 10030973 Oral discomfort PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-004449-35 Sponsor Protocol Number: 80-86600-98-19047 Start Date*: 2021-05-06
    Sponsor Name:ZonMw
    Full Title: Antibiotic treatment following surgical drainage of perianal abscess: a double-blind, placebo-controlled, randomized trial
    Medical condition: Perianal fistula
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2006-006143-31 Sponsor Protocol Number: AUX-CC-854.01 Start Date*: 2007-10-19
    Sponsor Name:Auxilium UK Limited
    Full Title: A Phase 3, Open Label Study of Safety and Efficacy of AA4500 in the Treatment of Subjects With Dupuytren's Contracture
    Medical condition: Dupuytren's Contracture
    Disease: Version SOC Term Classification Code Term Level
    8.1 10013872 Dupuytren's contracture LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) FI (Completed) DK (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2012-000191-41 Sponsor Protocol Number: GC28210 Start Date*: 2012-06-19
    Sponsor Name:GENENTECH, Inc.
    Full Title: A PHASE II, RANDOMIZED, PLACEBO-CONTROLLED, DOUBLE-BLIND STUDY OF THE SAFETY AND EFFICACY OF MPSK3169A IN PATIENTS WITH CORONARY HEART DISEASE OR HIGH RISK OF CORONARY HEART DISEASE
    Medical condition: Coronary Heart Disease or High Risk of Coronary Heart Disease
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10068617 Coronary heart disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) DE (Completed) CZ (Completed) SK (Completed)
    Trial results: View results
    EudraCT Number: 2016-000298-20 Sponsor Protocol Number: CHL.3/01-2016 Start Date*: 2016-10-18
    Sponsor Name:Sintetica S.A.
    Full Title: Comparison of epidural Chloroprocaine 3% and Ropivacaine 0.75% for unplanned Caesarean section in labouring women who have an epidural catheter in situ
    Medical condition: Local epidural anaesthesia in labouring women who have an epidural catheter in situ and established analgesia and need unplanned Caesarean
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10024758 Local anaesthesia PT
    Population Age: Adults Gender: Female
    Trial protocol: BE (Prematurely Ended) DE (Prematurely Ended) AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-001568-35 Sponsor Protocol Number: RGHT000559 Start Date*: 2008-06-24
    Sponsor Name:BELFAST HEALTH & SOCIAL CARE TRUST
    Full Title: Comparison of fascia iliac compartment block with conventional sedation to facilitate the positioning of patients with fractured neck of femur for spinal anaesthesia and the effect of nerve blockad...
    Medical condition: Investigation of the use a Fascia Iliaca nerve blockade for both positioning for spinal anaesthesia and postoperative analgesia in patients undergoing operative repair of fractured neck of femur.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2019-001167-75 Sponsor Protocol Number: FIBEA-04-EC-19-ALV Start Date*: 2019-09-09
    Sponsor Name:BTI I MAS D
    Full Title: Randomized Clinical Trial, conventional treatment-controlled, studying the efficacy of Plasma Rich in Growth Factor (PRGF®) in alveolar ridge preservation after simple exodontia in the anterior reg...
    Medical condition: Alveolar ridge preservation after exodontia of uniradiculate dental pience in the anterior region of maxilla
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-000180-70 Sponsor Protocol Number: 2020-09(04) Start Date*: 2021-05-31
    Sponsor Name:Beacon Hospital
    Full Title: Knee osteoarthritis Injection Therapy (KNiT) trial
    Medical condition: Knee osteoarthritis (OA). Osteoarthritis (OA) is a debilitating disease which mostly affects people over 60 years of age. It is known to be within the top 10 contributors to years lived with disabi...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: IE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2016-004545-91 Sponsor Protocol Number: 59874 Start Date*: 2017-04-13
    Sponsor Name:VU University Medical Center, department of reproductive Medicine
    Full Title: Continuous use of Oral contraceptives as an alternative for long term Pituitary down-regulation with GnRH agonist prior to IVF/ICSI in Endometriosis patients: a randomised controlled trial (COPIE t...
    Medical condition: The research population consists of women with surgically confirmed endometriosis ASRM stage III or IV or endometrioma on transvaginal ultrasound or MRI, scheduled for an IVF/ICSI treatment.
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-002942-19 Sponsor Protocol Number: NT-2020 Start Date*: 2021-03-16
    Sponsor Name:Region Örebro län
    Full Title: NORDTREAT The Nordic IBD treatment strategy trial – a randomized controlled trial of access to a protein profile
    Medical condition: Crohn's disease and Ulcerative colitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Completed) DK (Completed) IS (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-004611-61 Sponsor Protocol Number: DaPro Start Date*: 2008-08-19
    Sponsor Name:Medizinische Hochschule Hannover (MHH)
    Full Title: Prospektive, randomisierte, monozentrische 2-armige Studie zum Einsatz von Daptomycin in der antibiotischen Prophylaxe von sternalen Wundinfektionen nach medianer Sternotomie
    Medical condition: Incidence of sternal wound infections after cardiac surgery via median sternectomy and use of the heart-lung machine.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10036410 Postoperative wound infection LLT
    9.1 10053562 Surgical wound infection LLT
    9.1 10054091 Wound infection due to staphylococcus aureus LLT
    9.1 10059442 Wound infection staphylococcal LLT
    9.1 10063528 MRSA wound infection LLT
    9.1 10065240 Wound infection bacterial LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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