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Clinical trials for Understanding

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44358   clinical trials with a EudraCT protocol, of which   7384   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    1,691 result(s) found for: Understanding. Displaying page 1 of 85.
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    EudraCT Number: 2009-011248-21 Sponsor Protocol Number: Start Date*: 2009-06-29
    Sponsor Name:
    Full Title: het optimaliseren van de voorbereiding voor sigmoidoscopie in de regio; Moviprep versus Bisacodyl/klysma, een enkelblind gerandomiseerd onderzoek
    Medical condition: Bowel preparation for sigmoidoscopy.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-012372-27 Sponsor Protocol Number: 200901 Start Date*: 2009-09-17
    Sponsor Name:LUMC
    Full Title: The Sevoflurane study, understanding the effects of Sevoflurane to improve safety and outcome of cardiac surgery
    Medical condition: myocardial ischemia reperfusion injury during cardiac surgery
    Disease: Version SOC Term Classification Code Term Level
    9.1 10017501 Functional disturbances following cardiac surgery LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-000683-30 Sponsor Protocol Number: CoVacc Start Date*: 2021-03-03
    Sponsor Name:Umeå university
    Full Title: CoVacc - Immune response to vaccination against Covid-19, an open multicenter phase IV study
    Medical condition: Individuals with and without pre-existing immunity to Covid-19.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2015-005113-73 Sponsor Protocol Number: 20150114 Start Date*: 2016-07-01
    Sponsor Name:University Medical Center Groningen
    Full Title: Rotation for Optimal Targeting of Albuminuria and Treatment Evaluation
    Medical condition: Type 2 diabetes with albuminuria
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-006713-25 Sponsor Protocol Number: ASSENTE Start Date*: 2008-09-23
    Sponsor Name:OSPEDALE MAGGIORE DI MILANO (IRCCS)
    Full Title: A SINGLE-ARM PILOT STUDY WITH LOW-DOSE RITUXIMAB PLUS STANDARD ORAL PREDNISONE IN IDIOPATHIC AUTOIMMUNE HEMOLYTIC ANEMIA
    Medical condition: ANEMIE EMOLITICHE AUTOIMMUNI IDIOPATICHE
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-002230-41 Sponsor Protocol Number: PPH-LYF02 Start Date*: 2015-06-29
    Sponsor Name:Landspitali University Hospital
    Full Title: Pharmacokinetics of Proton Pump Inhibitors in a random Icelandic Population.
    Medical condition: Gastro Oesophageal Reflux Disease
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: IS (Completed)
    Trial results: View results
    EudraCT Number: 2006-003133-33 Sponsor Protocol Number: EMG-2006 Start Date*: 2006-07-14
    Sponsor Name:Hôpital Erasme
    Full Title: Etude des effets d’un antagoniste non spécifique de l’endothéline (le bosentan) sur l’activité orthosympathique et le chémoréflexe.
    Medical condition: healthy subjects obstructive sleep apnea (Bosentan is used in clinic in pulmonary hypertension)
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2009-016911-39 Sponsor Protocol Number: 113954 Start Date*: 2010-05-05
    Sponsor Name:GlaxoSmithKline Biologicals
    Full Title: An open, phase IV, multicentre, study to assess the long-term persistence of antibodies against hepatitis B and the immune response to a hepatitis B vaccine challenge in healthy children aged 11-12...
    Medical condition: Antibody persistence and hepatitis B vaccine challenge at 11-12 years of age (excluding 13th birthday), after primary vaccination with GSK Biologicals’ DTPa-HBV-IPV/Hib vaccine (Infanrix hexa) or G...
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: SK (Completed)
    Trial results: View results
    EudraCT Number: 2016-000728-24 Sponsor Protocol Number: MEBENDAZOLGAI3003 Start Date*: 2016-03-01
    Sponsor Name: Janssen Research & Development, LLC
    Full Title: A Double-Blind, Randomized, Multi-Center, Parallel-Group, Placebo-Controlled Study to Evaluate the Efficacy and Safety of a Single Dose of a 500-mg Chewable Tablet of Mebendazole in the Treatment o...
    Medical condition: Helminth infections
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2018-003083-30 Sponsor Protocol Number: PLAQHV Start Date*: 2019-01-31
    Sponsor Name:UZ Leuven
    Full Title: The effect of hydroxychloroquine sulphate on hedonic food intake, appetite-related sensations and gastrointestinal hormone release in healthy female subjects
    Medical condition: The study is meant to have a better understanding in obesity and how we can prevent/cure it. Therefore, the product will first be tested in healthy, lean volunteers.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10027433 - Metabolism and nutrition disorders 10029883 Obesity PT
    Population Age: Adults Gender: Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2007-005534-36 Sponsor Protocol Number: Scope Start Date*: 2008-02-04
    Sponsor Name:King's College Hospital [...]
    1. King's College Hospital
    2. King's College London
    Full Title: The effect of Exenatide on satiety, metabolic parameters and regional brain activation in response to nutrient ingestion in Type 2 diabetes.
    Medical condition: The brainメs response to food ingestion can be imaged and preliminary data suggest that these responses are different in the obese and insulin resistant. We will investigate the hypothesis that Exen...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2012-001779-35 Sponsor Protocol Number: 4 Start Date*: 2013-02-15
    Sponsor Name:University of Southampton
    Full Title: The effects of pregabalin augmentation of antidepressant drug on neuro-cognitive functioning in patients with generalized anxiety disorder
    Medical condition: Generalised anxiety disorder
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004873 10018105 Generalized anxiety disorder LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2021-002909-10 Sponsor Protocol Number: P137 Start Date*: 2022-10-24
    Sponsor Name:Maastricht University
    Full Title: THE IMPACT OF PSILOCYBIN ON PAIN IN FIBROMYALGIA PATIENTS AND HEALTHY VOLUNTEERS: A MULTICENTER TRIAL
    Medical condition: Fibromyalgia
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2016-002161-56 Sponsor Protocol Number: NeM-CSM-FT-01 Start Date*: 2017-04-13
    Sponsor Name:Mateusz Gola
    Full Title: Towards the understanding of neuronal mechanisms of compulsive sexual behaviors - pharmacotherapy
    Medical condition: compulsive sexual behavior (hypersexual disorder)
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: PL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-001877-34 Sponsor Protocol Number: HOT-Treated Start Date*: 2016-11-25
    Sponsor Name:South London and Maudsley NHS Foundation Trust [...]
    1. South London and Maudsley NHS Foundation Trust
    2. King's College London
    Full Title: Improving understanding of Heroin Overdose Testing: diamorphine dose-escalation testing in a treated population
    Medical condition: Opioid Overdose
    Disease: Version SOC Term Classification Code Term Level
    21.1 10022117 - Injury, poisoning and procedural complications 10033295 Overdose PT
    20.0 10022117 - Injury, poisoning and procedural complications 10033299 Overdose effect LLT
    20.1 10022117 - Injury, poisoning and procedural complications 10067695 Acute overdose LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2006-001509-26 Sponsor Protocol Number: DESG-01 Start Date*: 2006-10-11
    Sponsor Name:Dermal Laboratories Limited
    Full Title: An open evaluation of an emollient shower gel for dry skin conditions.
    Medical condition: Dry or chapped skin conditions which may also be pruritic (itchy) or inflamed e.g. eczema, psoriasis, elderly pruritus and dermatitis.
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-003854-80 Sponsor Protocol Number: 02B2005 Start Date*: 2006-01-31
    Sponsor Name:Department of Experimental and Clinical Pharmacology and Toxicology, Friedrich-Alexander-University
    Full Title: Modulation of the Surgical Inflammatory Response by Etoricoxib: Peripheral versus Central
    Medical condition: Patients with osteoarthritis undergoing elective primary single hip arthroplasty
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2017-004735-37 Sponsor Protocol Number: NL60549.078.17 Start Date*: 2018-03-05
    Sponsor Name:Erasmus University Rotterdam
    Full Title: Can Acetaminophen Ease the Heartbreak of Social Rejection?
    Medical condition: Healthy participants
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-005194-30 Sponsor Protocol Number: P-AD337-021 Start Date*: 2006-06-12
    Sponsor Name:Arakis Ltd.
    Full Title: A multi-centre, randomised, double-blind, placebo controlled, parallel group exploratory study to investigate the efficacy, safety and tolerability of AD 337 in the treatment of fibromyalgia in fem...
    Medical condition: Fibromyalgia
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-001131-30 Sponsor Protocol Number: EZ-2053-001 Start Date*: 2005-07-22
    Sponsor Name:Fresenius Biotech North America
    Full Title: A Double-Blind, Placebo-Controlled, Multicenter, Dose-ranging Study of an Anti-T-lymphocyte Immunglobuline (EZ-2053) in the Prophylaxis of Acute Pulmonary Allograft Rejection in Adult Recipients of...
    Medical condition: Patients with end-stage pulmonary failure, who are receiving a primary single or double pulmonary allograft
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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