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Clinical trials for Wrinkles

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    22 result(s) found for: Wrinkles. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2009-010338-23 Sponsor Protocol Number: RD.03.SPR.29081 Start Date*: 2009-06-09
    Sponsor Name:GALDERMA Research & Development
    Full Title: Intra-individual randomized comparison of the efficacy of two botulinum toxins type A on moderate to severe forehead wrinkles after one injection
    Medical condition: Moderate to severe forehead wrinkles
    Disease: Version SOC Term Classification Code Term Level
    9.1 10040954 Skin wrinkling LLT
    Population Age: Adults Gender: Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-005396-17 Sponsor Protocol Number: MRZ 60201-0617/1 Start Date*: 2007-05-30
    Sponsor Name:Merz Pharmaceuticals GmbH
    Full Title: A prospective, randomized, double-blinded, international multicenter trial to investigate the efficacy and safety of NT 201 in comparison to placebo and to compare two different application schemes...
    Medical condition: Treatment of lateral periorbital wrinkles ("Crow's feet")
    Disease: Version SOC Term Classification Code Term Level
    9.1 10052611 Crow's feet LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed) FR (Completed) IT (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-003639-59 Sponsor Protocol Number: 06-RHY-002 Start Date*: 2007-01-16
    Sponsor Name:Intercytex
    Full Title: A phase IIa open-label dose-escalation study using ICX-RHY to enhance the aesthetic appearance of nasolabial folds
    Medical condition: Moderately severe wrinkles
    Disease: Version SOC Term Classification Code Term Level
    8.1 10048042 Wrinkles LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-020828-21 Sponsor Protocol Number: 191622-099 Start Date*: Information not available in EudraCT
    Sponsor Name:Allergan Limited
    Full Title: A Multicenter, Double-Blind, Randomized, Placebo-Controlled, Parallel-Group Study to Evaluate the Safety and Efficacy of BOTOX® (Botulinum Toxin Type A) Purified Neurotoxin Complex in Subjects with...
    Medical condition: Treatment of lateral canthal rhytides in the periorbital region (CFL)
    Disease: Version SOC Term Classification Code Term Level
    13.1 10040785 - Skin and subcutaneous tissue disorders 10040954 Skin wrinkling PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2010-020827-28 Sponsor Protocol Number: 191622-098 Start Date*: 2011-06-10
    Sponsor Name:Allergan Limited
    Full Title: A Multicenter, Double-Blind, Randomized, Placebo-Controlled, Parallel-Group, Single Treatment Cycle Study of BOTOX® (Botulinum Toxin Type A) Purified Neurotoxin Complex in Subjects with Lateral Can...
    Medical condition: Treatment of lateral canthal rhytides in the periorbital region (Crow's Feet Lines)
    Disease: Version SOC Term Classification Code Term Level
    13.1 10040785 - Skin and subcutaneous tissue disorders 10040954 Skin wrinkling PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-004592-36 Sponsor Protocol Number: RD.03.SPR.29097 Start Date*: 2012-04-12
    Sponsor Name:Galderma R&D
    Full Title: Subjects’ satisfaction on pan facial aesthetic enhancement after treatment with Azzalure® and the Restylane® range
    Medical condition: Facial volume loss and dynamic wrinkles of the upper third of the face
    Disease: Version SOC Term Classification Code Term Level
    14.0 10040785 - Skin and subcutaneous tissue disorders 10040954 Skin wrinkling PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2014-003770-16 Sponsor Protocol Number: MRZ60201_3100_1 Start Date*: 2015-04-16
    Sponsor Name:Merz Pharmaceuticals GmbH
    Full Title: A prospective, open-label, multicenter, repeat-dose trial to investigate the safety and efficacy of NT 201 (incobotulinumtoxinA) in the combined treatment of upper facial lines (horizontal forehead...
    Medical condition: Upper facial lines (horizontal forehead lines, glabellar frown lines, and lateral periorbital lines)
    Disease: Version SOC Term Classification Code Term Level
    19.1 10040785 - Skin and subcutaneous tissue disorders 10040954 Skin wrinkling PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-005958-23 Sponsor Protocol Number: Y-47-52120-128 Start Date*: 2008-03-03
    Sponsor Name:Ipsen Group, SCRAS Institut Henri Beaufour
    Full Title: A Phase II, Randomised, Double-Blind Study to Compare the Safety and Efficacy of One Treatment Cycle of Clostridium Botulinum Type A Toxin (50 Units) When Reconstituted from Either a 125 Unit or a ...
    Medical condition: Moderate to severe vertical glabellar lines.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10052609 Glabellar frown lines LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2020-001318-39 Sponsor Protocol Number: UNIHHSkinQuality202000401 Start Date*: 2021-04-30
    Sponsor Name:Prof. Dr. Martina Kerscher, University of Hamburg
    Full Title: Skin perception after intradermal application of IncobotulinumtoxinA within upper and midface (Interventional Phase II)
    Medical condition: Skin perception after intradermal application of INCOBOTULINUMTOXIN A within upper and midface
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-004278-32 Sponsor Protocol Number: 14031972 Start Date*: 2020-12-04
    Sponsor Name:Falck clinic
    Full Title: Satisfaction study of split doses botulinum toxin with double frequency
    Medical condition: Wrinkles, fine lines
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2010-021271-83 Sponsor Protocol Number: 191622-104 Start Date*: 2011-04-27
    Sponsor Name:Allergan Limited
    Full Title: A Multicenter, Double-blind, Randomized, Placebo-controlled, Parallel-group Extension Study to Evaluate the Safety and Efficacy of BOTOX® (Botulinum Toxin Type A) Purified Neurotoxin Complex in Sub...
    Medical condition: Treatment of lateral canthal rhytides in the periorbital region (CFL)
    Disease: Version SOC Term Classification Code Term Level
    12.1 10040954 Skin wrinkling LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2011-005887-20 Sponsor Protocol Number: MRZ60201_3076_1 Start Date*: 2012-07-17
    Sponsor Name:Merz Pharmaceuticals GmbH
    Full Title: A prospective, randomized, double-blind, placebo-controlled, multicenter study with an open-label extension period to investigate the efficacy and safety of NT 201 in the combined treatment of uppe...
    Medical condition: Upper facial lines (horizontal forehead lines, glabellar frown lines, and lateral periorbital lines)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10040785 - Skin and subcutaneous tissue disorders 10040954 Skin wrinkling PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2019-004113-13 Sponsor Protocol Number: M602011070 Start Date*: 2020-08-17
    Sponsor Name:Merz Pharmaceuticals GmbH
    Full Title: A prospective, randomized, double-blind, placebo-controlled, multicenter study with an open-label extension period to investigate the efficacy and safety of NT 201 in the simultaneous treatment of ...
    Medical condition: Moderate to severe upper facial lines (horizontal forehead lines, glabellar frown lines, and lateral canthal lines)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10040785 - Skin and subcutaneous tissue disorders 10048042 Wrinkles LLT
    21.1 10040785 - Skin and subcutaneous tissue disorders 10052609 Glabellar frown lines LLT
    20.0 10040785 - Skin and subcutaneous tissue disorders 10052611 Crow's feet LLT
    21.1 10040785 - Skin and subcutaneous tissue disorders 10040954 Skin wrinkling PT
    20.0 10040785 - Skin and subcutaneous tissue disorders 10040785 Skin and subcutaneous tissue disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2014-001815-38 Sponsor Protocol Number: 191622-143 Start Date*: 2014-12-16
    Sponsor Name:Allergan Limited
    Full Title: Evaluation of the Safety and Efficacy of Treatment With BOTOX® (Botulinum Toxin Type A) Purified Neurotoxin Complex for Subjects With Facial Rhytides (Forehead Lines, Glabellar Lines, Lateral Canth...
    Medical condition: Facial Rhytides (Forehead Lines, Glabellar Lines, Lateral Canthal Lines)
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004858 10048043 Wrinkling LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) GB (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2014-001860-36 Sponsor Protocol Number: 191622-142 Start Date*: 2014-12-19
    Sponsor Name:Allergan Limited
    Full Title: Evaluation of the Safety and Efficacy of Treatment With BOTOX® (Botulinum Toxin Type A) Purified Neurotoxin Complex for Subjects With Forehead and Glabellar Facial Rhytides
    Medical condition: Facial Rhytides (Forehead Lines, Glabellar Lines)
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004858 10048043 Wrinkling LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Completed)
    Trial results: View results
    EudraCT Number: 2018-000189-12 Sponsor Protocol Number: LS2018 Start Date*: 2018-03-23
    Sponsor Name:Bispebjerg Hospital
    Full Title: Treatment of photodamaged skin of the décolleté with fractional laser, radio-frequency microneedling, and photodynamic therapy
    Medical condition: Photodamaged skin in the décolleté
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004858 10065944 Photodamaged skin LLT
    Population Age: Adults Gender: Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-000416-24 Sponsor Protocol Number: CRC-ACNE-A-05 Start Date*: 2013-06-21
    Sponsor Name:Charité-Universitätsmedizin Berlin, Department of Dermatology, Clinical Research Center for Hair and Skin Science
    Full Title: THE EFFECT OF AZELAIC ACID ON SYMPTOMS OF ACNE IN FEMALE PATIENTS AGE 20-45 WITH MILD TO MODERATE PAPULOPUSTULAR ACNE (ACNE TARDA)
    Medical condition: MILD TO MODERATE PAPULOPUSTULAR ACNE (ACNE TARDA)
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2011-004636-66 Sponsor Protocol Number: KP-2011-0077 Start Date*: 2011-12-05
    Sponsor Name:Uppsala University Hospital
    Full Title: Single-blinded randomized trial of Botulinumtoxin A (Vistabel®) and its objective paralytic effect in the facial muscles of healthy women: development of new neurophysiological measurements.
    Medical condition: The treatment of glabellar lines in healthy women by muscle paralysis from injection of botulinum toxin
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-002516-13 Sponsor Protocol Number: FollowTheSutures Start Date*: 2018-04-13
    Sponsor Name:St. Olavs hospital
    Full Title: “Follow the sutures“. An open multicenter, multinational pilot study to explore tolerability, safety and effect of a new procedure for injecting botulinum toxin in the head against chronic migraine.
    Medical condition: Chronic migraine
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NO (Completed)
    Trial results: View results
    EudraCT Number: 2014-003841-86 Sponsor Protocol Number: Y-52-52120-214 Start Date*: 2015-04-30
    Sponsor Name:Ipsen Innovation
    Full Title: A phase III, randomised, double blind, placebo controlled and open label phase, multicentre study to investigate the efficacy and safety of BTX-A-HAC NG in the treatment of moderate to severe glabe...
    Medical condition: Moderate to severe Glabellar lines
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004858 10052609 Glabellar frown lines LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) GB (Completed)
    Trial results: View results
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