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Clinical trials for Zonisamide

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
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    The EU Clinical Trials Register currently displays   44339   clinical trials with a EudraCT protocol, of which   7369   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    26 result(s) found for: Zonisamide. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2016-004958-14 Sponsor Protocol Number: E2090-S082-409 Start Date*: 2017-04-24
    Sponsor Name:Eisai Korea Inc.
    Full Title: A Korean Open-label, Multi-center, Community-based Trial Assessing the Efficacy and Safety of Zonisamide as Adjunctive Therapy in Patients With Uncontrolled Partial Epilepsy
    Medical condition: Epilepsy
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: (No results available)
    EudraCT Number: 2016-004956-32 Sponsor Protocol Number: E2090-S082-404 Start Date*: 2017-02-23
    Sponsor Name:Eisai Korea Inc.
    Full Title: A Multi-center Comparative Trial of Low and High Dose Zonisamide in Children with Newly Diagnosed Epilepsy as Monotherapy
    Medical condition: Epilepsy
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: (No results available)
    EudraCT Number: 2016-004957-33 Sponsor Protocol Number: E2090-S082-405 Start Date*: 2017-02-13
    Sponsor Name:Eisai Korea Inc.
    Full Title: Comparative Study of Zonisamide and Carbamazepine as an Initial Monotherapy: Efficacy and Safety Evaluation
    Medical condition: Epilepsy
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2006-000156-40 Sponsor Protocol Number: E2090-E044-310 Start Date*: 2007-07-03
    Sponsor Name:Eisai Limited
    Full Title: A randomized, multi-centre, double-blind study, to compare the efficacy and safety of zonisamide and carbamazepine as monotherapy, in newly diagnosed partial epilepsy
    Medical condition: Epilepsy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Prematurely Ended) FR (Completed) GB (Prematurely Ended) HU (Prematurely Ended) DE (Prematurely Ended) ES (Prematurely Ended) GR (Prematurely Ended) IT (Prematurely Ended) CZ (Completed) SK (Completed)
    Trial results: View results
    EudraCT Number: 2007-006695-10 Sponsor Protocol Number: E2090-E044-316 Start Date*: 2008-09-23
    Sponsor Name:Eisai Limited
    Full Title: Open Label Extension Study Following Double-blind, Randomized, Placebo-controlled, Multicenter Study to Assess Efficacy and Safety of Adjunctive Zonisamide in Primary Generalized Tonic-Clonic Seizures
    Medical condition: Primary generalised tonic-clonic seizures (PGTCS) in idiopathic generalised epilepsy (IGE)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10018101 Generalised tonic-clonic seizures HLT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: HU (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2016-004954-13 Sponsor Protocol Number: E2090-AS886-202 Start Date*: 2017-04-24
    Sponsor Name:Eisai Taiwan Inc.
    Full Title: A Multi-center, Randomized, Open-label, Parallel-group, Dose-titration, Add-on, Comparative Study in Evaluating the Efficacy and Safety of Zonisamide (Zonegran) and Lamotrigine (Lamictal) for Subje...
    Medical condition: Epilepsy
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: (No results available)
    EudraCT Number: 2016-004955-64 Sponsor Protocol Number: E2090-S082-403 Start Date*: 2017-04-21
    Sponsor Name:Eisai Korea Inc.
    Full Title: A Multicenter Comparative Trial of Zonisamide and Topiramate as Monotherapy in Epilepsy Patients: Safety for cognitive function
    Medical condition: Epilepsy
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: (No results available)
    EudraCT Number: 2005-001982-33 Sponsor Protocol Number: E2090-E044-401 Start Date*: 2005-09-05
    Sponsor Name:Eisai Limited
    Full Title: An open label study of Zonegran (zonisamide) in patients with partial onset seizures.
    Medical condition: Indicated as adjunctive therapy in the treatment of adult patients with partial seizures, with or without secondary generalisation.
    Disease: Version SOC Term Classification Code Term Level
    8.0 10061334 pt
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) AT (Completed) SE (Completed) DK (Completed) FI (Completed) DE (Prematurely Ended) IT (Completed)
    Trial results: View results
    EudraCT Number: 2007-006696-36 Sponsor Protocol Number: E2090-E044-318 Start Date*: 2008-09-05
    Sponsor Name:Eisai Limited
    Full Title: Open label Extension Study Following Double-blind, Randomized, Placebo-controlled, Multicentre Study to Assess Efficacy and Safety of Adjunctive Zonisamide in Myoclonic Seizures associated with Idi...
    Medical condition: myoclonic seizures in idiopathic generalised epilepsy (IGE).
    Disease: Version SOC Term Classification Code Term Level
    9.1 10054859 Myoclonic epilepsy LLT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: HU (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2006-002515-27 Sponsor Protocol Number: E2090-E044-312 Start Date*: 2008-02-21
    Sponsor Name:Eisai Ltd
    Full Title: A double-blind, randomised, placebo-controlled, multi-centre study to assess the efficacy and safety of adjunctive zonisamide in paediatric partial onset seizures
    Medical condition: Epilepsy
    Disease: Version SOC Term Classification Code Term Level
    9.1 10065336 Partial epilepsy LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: BE (Completed) HU (Completed) FR (Completed) LV (Completed) EE (Completed) PL (Completed) IT (Completed) ES (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-010895-64 Sponsor Protocol Number: E2090-E039-401 Start Date*: 2009-05-31
    Sponsor Name:Eisai s.r.l.
    Full Title: A superiority, randomized, open-label, multi-center study to compare the efficacy and safety of adjunctive zonisamide vs replacement with zonisamide of the last added antiepileptic drug in patients...
    Medical condition: Patients with localization-related epilepsy, who have added a second drug to the monotherapy, haven’t obtained an adequate reduction of seizure frequency with this combination and have responded to...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10065337 Focal epilepsy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2005-000260-57 Sponsor Protocol Number: ZNS-D-04-001 Start Date*: 2005-04-25
    Sponsor Name:Eisai GmbH
    Full Title: Randomized trial to assess efficacy and safety of an add-on treatment with zonisamide in adults with focal epileptic seizures with or without secondary generalization
    Medical condition: Partial epileptic seizures with or without secondary generalisation
    Disease: Version SOC Term Classification Code Term Level
    7.1 10040703 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2016-004951-55 Sponsor Protocol Number: E2090-AS086-311 Start Date*: 2017-04-24
    Sponsor Name:Eisai Inc.
    Full Title: A Multicenter, Placebo-controlled, Double-blind Study to Evaluate the Efficacy and Safety of Zonisamide in the Treatment of Partial Seizures
    Medical condition: Epilepsy
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: (No results available)
    EudraCT Number: 2006-002516-10 Sponsor Protocol Number: E2090-E044-402 Start Date*: 2008-11-18
    Sponsor Name:Eisai Ltd
    Full Title: A randomised, double blind, placebo-controlled study to evaluate the safety, tolerability and explore the efficacy of zonisamide as add-on therapy in elderly patients with refractory partial seizures.
    Medical condition: Epilepsy
    Disease: Version SOC Term Classification Code Term Level
    9.1 10065336 Partial epilepsy LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) NL (Prematurely Ended) HU (Completed) BE (Completed) GB (Prematurely Ended) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-003557-91 Sponsor Protocol Number: E2090-E044-315 Start Date*: 2008-07-09
    Sponsor Name:Eisai Limited
    Full Title: A double-blind, randomised, placebo-controlled, multicentre study to assess the efficacy and safety of adjunctive zonisamide in primary generalised tonic clonic seizures
    Medical condition: Primary generalised tonic-clonic seizures (PGTCS) in idiopathic generalised epilepsy (IGE)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10018101 Generalised tonic-clonic seizures HLT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: DE (Completed) HU (Prematurely Ended) LT (Prematurely Ended) FI (Prematurely Ended) CZ (Prematurely Ended) EE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-001159-23 Sponsor Protocol Number: E2090-E044-314 Start Date*: 2008-12-04
    Sponsor Name:Eisai Limited
    Full Title: A randomized, double-blind extension study to assess long-term safety and to explore long-term efficacy of zonisamide as monotherapy in newly diagnosed partial epilepsy
    Medical condition: Epilepsy
    Disease: Version SOC Term Classification Code Term Level
    9.1 10065336 Partial epilepsy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) IT (Completed) SK (Completed) FR (Completed) SE (Completed) DE (Completed) CZ (Completed) HU (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2007-003556-10 Sponsor Protocol Number: E2090-E044-317 Start Date*: 2008-07-09
    Sponsor Name:Eisai Limited
    Full Title: A double-blind, randomised, placebo-controlled, multi-centre study to assess the efficacy and safety of adjunctive zonisamide in myoclonic seizures associated with idiopathic generalised epilepsy.
    Medical condition: myoclonic seizures in idiopathic generalised epilepsy (IGE).
    Disease: Version SOC Term Classification Code Term Level
    9.1 10054859 Myoclonic epilepsy LLT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) HU (Prematurely Ended) LT (Prematurely Ended) CZ (Completed) EE (Prematurely Ended) PL (Completed) ES (Completed) FI (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2018-000781-10 Sponsor Protocol Number: STANDLOW Start Date*: 2018-05-31
    Sponsor Name:IRCCS- ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI
    Full Title: EFFICACY AND TOLERABILITY OF LOW VS. STANDARD DAILY DOSES OF ANTIEPILEPTIC DRUGS IN NEWLY DIAGNOSED, PREVIOUSLY UNTREATED EPILEPSY (STANDLOW). A MULTICENTER, RANDOMIZED, SINGLE-BLIND, PARALLEL GROU...
    Medical condition: EPILEPSY
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004852 10015046 Epilepsy, unspecified LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-000198-53 Sponsor Protocol Number: E2090-E044-313 Start Date*: 2008-05-26
    Sponsor Name:Eisai Ltd
    Full Title: An open-label extension study following a double-blind, randomised, placebo-controlled, multi-centre study to assess the efficacy and safety of adjunctive zonisamide in paediatric partial onset sei...
    Medical condition: Epilepsy
    Disease: Version SOC Term Classification Code Term Level
    9.1 10065336 Partial epilepsy LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: HU (Completed) BE (Completed) LV (Completed) IT (Completed) EE (Completed) PL (Completed) ES (Completed) FR (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-015859-24 Sponsor Protocol Number: Zon-001 Start Date*: 2010-02-24
    Sponsor Name:The Sahlgrenska Academy, University of Gothenburg
    Full Title:
    Medical condition: The objective is to explore the efficacy of pharmacological weight reduction compared with CPAP treatment in patients with moderate to severe obstructive sleep apnea (OSA).
    Disease: Version SOC Term Classification Code Term Level
    12.0 10055577 Obstructive sleep apnea syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Prematurely Ended)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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