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Clinical trials for addiction

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   43973   clinical trials with a EudraCT protocol, of which   7311   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    145 result(s) found for: addiction. Displaying page 1 of 8.
    1  2  3  4  5  6  7  8  Next»
    EudraCT Number: 2014-001284-12 Sponsor Protocol Number: PA-01 Start Date*: 2014-11-19
    Sponsor Name:University Medical Center Groningen
    Full Title: The Role of the Dopamine D2 Receptor System in Pornographic Addiction – A [11C]-Raclopride PET Study
    Medical condition: pornographic addiction
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-001088-28 Sponsor Protocol Number: BRIO Start Date*: 2016-01-14
    Sponsor Name:South London and Maudsley NHS Foundation Trust [...]
    1. South London and Maudsley NHS Foundation Trust
    2. King's College London
    Full Title: Feasibility, efficacy and acceptability of injected buprenorphine as treatment for opiate users who persist in injecting illicit heroin through opiate maintenance treatment
    Medical condition: Addiction to illicit heroin
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004873 10019935 Heroin addiction LLT
    18.1 100000004873 10001127 Addiction to drugs LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-004102-14 Sponsor Protocol Number: 8123 Start Date*: 2008-10-23
    Sponsor Name:Kansanterveyslaitos
    Full Title: Rahapeliriippuvuuden hoitaminen kohdennetulla naltreksonilääkityksellä ja oppimismallilla
    Medical condition: Peliriippuvuus, muuten terveitä
    Disease: Version SOC Term Classification Code Term Level
    9.1 10017657 Gambling pathological LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-021123-26 Sponsor Protocol Number: 03062010 Start Date*: 2010-10-29
    Sponsor Name:National Institute for Health and Welfare
    Full Title: Kaksoissokkoutettu kliininen hoitotutkimus: Rahapeliriippuvuuden hoitaminen opiaattisalpaaja naltreksonilla ja oppimismallilla
    Medical condition: Pathological gambling dependence
    Disease: Version SOC Term Classification Code Term Level
    12.1 10017657 Gambling pathological LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-001216-23 Sponsor Protocol Number: Clockstop 1, Start Date*: 2007-06-20
    Sponsor Name:Phoenux AG
    Full Title: Phase I Studie bei substituirten chronischen Opiatgebrauchern zur Aufhebung zusätzlicher Opioidwirkungen einer weiteren Opiatgebrauchern zur Aufhebung zusätlicher Opioidwirkungen einer weiteren Opi...
    Medical condition: Opiate addiction
    Disease: Version SOC Term Classification Code Term Level
    9.1 10019935 Heroin addiction LLT
    Population Age: Adults Gender: Male
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-005235-14 Sponsor Protocol Number: P05042 Start Date*: 2007-07-11
    Sponsor Name:Integrated Therapeutics Group Inc
    Full Title: A Randomized Acceptability and Safety Study of Suboxone Induction in Heroin Users
    Medical condition: Opioid dependence
    Disease: Version SOC Term Classification Code Term Level
    9.1 10013663 Drug dependence LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) GB (Completed) ES (Completed) CZ (Completed) PT (Completed) SI (Completed) DE (Completed) IE (Completed) IT (Completed) LT (Completed) SK (Completed)
    Trial results: View results
    EudraCT Number: 2008-001786-28 Sponsor Protocol Number: 2008-6-CC Start Date*: 2009-08-20
    Sponsor Name:Academical Medical Center
    Full Title: Innovative approaches for cocaine pharmacotherapy using fMRI: The case of varenicline
    Medical condition: cocaine addiction
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-003188-36 Sponsor Protocol Number: WI218780 Start Date*: 2018-03-08
    Sponsor Name:Lapland Central Hospital
    Full Title: Keski-ikäisten pitkään tupakoineiden tupakasta vieroitus sähkötupakalla
    Medical condition: Nicotine addiction
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004873 10056478 Nicotine addiction LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-000420-34 Sponsor Protocol Number: CHUB-NAC-Craving Start Date*: 2018-11-27
    Sponsor Name:Centre Hospitalier Universitaire Brugmann
    Full Title: Efficacy of N-acetylcysteine on the craving symptoms of hospitalized patients with cocaine addiction.
    Medical condition: Cocaine addiction
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004873 10009817 Cocaine dependence LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-019381-90 Sponsor Protocol Number: p57 Start Date*: 2010-07-05
    Sponsor Name:universiteit Maastricht
    Full Title: an fMRI study on the effects of NicVAX and placebo on Central Nervous System activation and behaviour following a nicotine challenge
    Medical condition: Nicotine addiction/smoking
    Disease: Version SOC Term Classification Code Term Level
    12.1 10056478 Nicotine addiction LLT
    12.1 10056484 Nicotine craving LLT
    12.1 10057852 Nicotine dependence LLT
    Population Age: Adults Gender: Male
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2022-002462-32 Sponsor Protocol Number: SHW01 Start Date*: 2022-12-09
    Sponsor Name:Suchthilfe Wien gGmbH
    Full Title: Pilot study on the safety and feasibility of intravenous opioid agonist therapy (OAT) with Hydagelan® (hydromorphone hydrochloride) in Vienna.
    Medical condition: Opioid dependence: Opioid dependence is a serious and usually chronic disease that requires treatment, encompasses various psychological and physical dimensions, and is associated with concomitant ...
    Disease: Version SOC Term Classification Code Term Level
    23.1 100000004873 10013658 Drug addiction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-001828-56 Sponsor Protocol Number: NalPilo Start Date*: 2016-12-09
    Sponsor Name:National Institute for Health and Welfare
    Full Title:
    Medical condition: Problem gambling
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004873 10017657 Gambling pathological LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: View results
    EudraCT Number: 2014-002708-26 Sponsor Protocol Number: CRC341 Start Date*: 2017-06-28
    Sponsor Name:University of Surrey
    Full Title: A randomised double blind placebo controlled pilot trial of oxytocin efficacy in treating detoxified opioid dependent individuals
    Medical condition: Opioid dependence. The study will be investigating the efficacy of Syntocinon (oxytocin) on treating the withdrawal symptoms and cravings that opioid (e.g. almost always heroin) dependent individua...
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004873 10057379 Addiction relapse LLT
    20.0 100000004873 10001126 Addiction any drug LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2004-001929-20 Sponsor Protocol Number: TEST-APO Start Date*: 2010-05-18
    Sponsor Name:Servicio de Psiquiatría. Hospital Universitari Vall d’Hebron
    Full Title: EL TEST DE APOMORFINA COMO MARCADOR BIOLÓGICO DE LAS RECAÍDAS EN PACIENTES DEPENDIENTES DE SUSTANCIAS PSICOTROPAS
    Medical condition: Dependencia de alcohol Dependencia de cocaína Dependencia de heroína
    Disease: Version SOC Term Classification Code Term Level
    9 10001590 Alcohol addiction LLT
    9 10009815 Cocaine addiction LLT
    9 10019935 Heroin addiction LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-005234-21 Sponsor Protocol Number: P04843 Start Date*: 2007-11-28
    Sponsor Name:Schering-Plough Research Institute
    Full Title: A Randomized Acceptability and Safety Study of the Transfer From Subutex to Suboxone in Opioid-Dependent Subjects.
    Medical condition: Opioid dependance
    Disease: Version SOC Term Classification Code Term Level
    9.1 10013663 Drug dependence LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) GB (Completed) SE (Completed) PT (Completed) DK (Completed) LT (Completed) SI (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2008-001397-32 Sponsor Protocol Number: 2480/2008 Start Date*: 2008-05-14
    Sponsor Name:ASL 5 di PISA-ZONA VALDERA
    Full Title: ARIPIPRAZOLE VERSUS ROPIRINOLE: A PILOT , OPEN-LABEL, PROSPECTIVE, RANDOMISED, CONTROLLED, MULTICENTRIC TRIAL, IN THERAPY WITH ROPIRINOLE OR ARIPIPRAZOLE FOR COCAINE DEPENDENCE
    Medical condition: TERAPY FOR COCAINE DEPENDENCE
    Disease: Version SOC Term Classification Code Term Level
    9.1 10009815 Cocaine addiction LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2006-004921-27 Sponsor Protocol Number: 1 Start Date*: 2006-12-15
    Sponsor Name:Psykiatrisk Center Gentofte
    Full Title: Antabuse in severe alcoholism: an open controlled study
    Medical condition: Alcoholism
    Disease: Version SOC Term Classification Code Term Level
    8.1 10001639 Alcoholism LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2013-002584-25 Sponsor Protocol Number: 10/46/01 Start Date*: 2014-11-06
    Sponsor Name:King's College London [...]
    1. King's College London
    2. South London and Maudsley NHS Foundation Trust
    Full Title: Naltrexone Enhanced Addiction Treatment (NEAT): A randomised controlled trial of the clinical and cost-effectiveness of extended-release naltrexone and oral naltrexone.
    Medical condition: Opiate addiction
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004873 10019935 Heroin addiction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-006886-18 Sponsor Protocol Number: ALK21-014 Start Date*: 2007-06-04
    Sponsor Name:Alkermes Inc
    Full Title: Efficacy and Safety of Vivitrol® in Adults Completing Inpatient Treatment for Alcohol Dependence
    Medical condition: Alcohol Dependence
    Disease: Version SOC Term Classification Code Term Level
    9.1 10001590 Alcohol addiction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2006-000713-37 Sponsor Protocol Number: 127 Start Date*: 2006-02-20
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: Intervention Baclofen Intervention Study
    Medical condition: treatment of dependence in alcohol addiction
    Disease: Version SOC Term Classification Code Term Level
    9.1 10001639 Alcoholism LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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