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Clinical trials for Clonidine

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    89 result(s) found for: Clonidine. Displaying page 1 of 5.
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    EudraCT Number: 2015-001699-23 Sponsor Protocol Number: Clonkin1 Start Date*: 2015-12-01
    Sponsor Name:Deventer Hospital
    Full Title: Pharmacokinetics and clinical effects of escalating doses of clonidine in ICU patients
    Medical condition: Delirium The pharmacokinetic and dynamic properties of intravenous clonidine in critical ill mechanically treated patients
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-003678-82 Sponsor Protocol Number: CHDR0606 Start Date*: 2007-07-10
    Sponsor Name:Centre for Human Drug Research
    Full Title: Pharmacokinetics and effects of oral clonidine in children with suspected Growth Hormone deficiency
    Medical condition: Clonidine is studied in the paediatric population, more specific children with short stature. It is used as a diagnostic tool to establish Growth Hormone reserve in routine practice.
    Disease: Version SOC Term Classification Code Term Level
    8.1 10005573 Blood growth hormone decreased LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2014-003582-24 Sponsor Protocol Number: CLON01 Start Date*: 2015-06-15
    Sponsor Name:Universitätsklinikum Erlangen
    Full Title: A double blind, randomised, multicentre, active controlled, parallel-group, phase III trial to evaluate the efficacy, safety and pharmacokinetics of intravenous clonidine (hydrochloride) compared t...
    Medical condition: sedation in intensive care
    Disease: Version SOC Term Classification Code Term Level
    18.1 10029205 - Nervous system disorders 10039897 Sedation PT
    Population Age: Preterm newborn infants, Newborns, Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Completed) DE (Prematurely Ended) SE (Completed) IT (Prematurely Ended) CZ (Completed) EE (Prematurely Ended) ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-000815-26 Sponsor Protocol Number: LUCID Start Date*: 2013-08-26
    Sponsor Name:Oslo University Hospital
    Full Title: THE OSLO STUDY OF CLONIDINE IN ELDERLY PATIENTS WITH DELIRIUM
    Medical condition: Delirium in elderly patients admitted to the acute geriatric ward
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: NO (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2008-004471-22 Sponsor Protocol Number: GE 06-2008 Start Date*: 2008-09-01
    Sponsor Name:ISTITUTO GIANNINA GASLINI
    Full Title: Minimum local anesthetic concentration of levobupivacaine and clonidine given for caudal anesthesia in children
    Medical condition: postoperative pain management
    Disease: Version SOC Term Classification Code Term Level
    9.1 10036276 Postoperative analgesia LLT
    Population Age: Newborns, Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-003560-74 Sponsor Protocol Number: p2011-1 Start Date*: 2012-09-25
    Sponsor Name:Leiden University Medical Center
    Full Title: Effectiveness of Clonidine for the treatment of radicular pain: A randomized, double-blind and prospective study. (EFFOC study)
    Medical condition: Radicular lumbar pain
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-024100-10 Sponsor Protocol Number: OZR-2010-17 Start Date*: 2011-03-28
    Sponsor Name:The Rotterdam Eye Hospital
    Full Title: Clonidine as an adjuvant to prolong local anaesthesia in ophthalmic surgery with cryocoagulation. A randomized, controlled, patient-masked trial.
    Medical condition: - Rhegmatogenous retinal detachment requiring cryocoagulation and episcleral explant. - Glaucoma requiring cryocoagulation of the ciliary body.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2007-005512-12 Sponsor Protocol Number: MVDV Start Date*: 2007-12-19
    Sponsor Name:University Hospitals Leuven
    Full Title: Een verbetering van de analgesie na episiotomie door epidurale toediening van neostigmine en clonidine.
    Medical condition: Combinedn spinal-epidural analgesia during labour.
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2014-003008-53 Sponsor Protocol Number: 80836009820016 Start Date*: 2014-12-10
    Sponsor Name:University Medical Center Utrecht
    Full Title: Clonidine Augmentation Therapy in Schizophrenia
    Medical condition: Schizophrenia, schizophreniform disorder, schizoaffective disorder
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-014870-16 Sponsor Protocol Number: BA2009-28-01 Start Date*: 2009-12-10
    Sponsor Name:BioAlliance Pharma
    Full Title: A phase II, multicentre, randomized, double-blind, placebo-controlled study comparing the efficacy and safety of Clonidine Lauriad® 50 μg and 100 μg mucoadhesive buccal tablet (MBT) applied once da...
    Medical condition: Prevention and treatment of chemoradion therapy-induced oral mucositis.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Completed) ES (Completed) DE (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2012-005215-42 Sponsor Protocol Number: KloMid02 Start Date*: 2013-04-12
    Sponsor Name:Department of Anesthesiology and Intensive Care Medicine
    Full Title: Children's mood/anxiety, pain, nausea and behavioral changes after premedication with Clonidine versus Midazolam in ENT day surgery.
    Medical condition: Preanesthetic Medication at ear-nose-throat surgery
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-011059-27 Sponsor Protocol Number: RBHP 2009 BONNIN Start Date*: 2009-06-17
    Sponsor Name:CHU Clermont-Ferrand
    Full Title: Etude des effets de l’adjonction de clonidine au mélange anesthésique local + opiacé destiné à l’infusion péridurale autocontrôlée pour l’analgésie du travail obstétrical (lévobupivacaïne 0,568 mg/...
    Medical condition: parturiente en cours de travail obstétrical
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-004796-35 Sponsor Protocol Number: EPICLO2006 Start Date*: 2007-04-20
    Sponsor Name:R&D Department, Box 146, Addenbrooke's Hospital
    Full Title: A study of effect of epidural clonidine on postoperative pain relief, hyperalgesia and chronic pain in patients undergoing colorectal surgery
    Medical condition: 1. Postoperative pain and hyperalgesia following laparotomy for colorectal surgery 2. Chronic pain following laparotomy for colorectal surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2006-005845-12 Sponsor Protocol Number: 11/2006 - MVdV Start Date*: 2007-01-08
    Sponsor Name:UZ leuven, Marc Van de Velde
    Full Title: Combined spinal-epidural anaesthesia during labour : has the epidural administration of clonidine and neostigmine a positive influence on the quality of analgesia ?
    Medical condition: combined spinal-epidural analgesia during labour
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2008-008434-36 Sponsor Protocol Number: VDV12/08 Start Date*: 2009-02-12
    Sponsor Name:Marc Van de Velde
    Full Title: Een gecombineerde spinale epidurale anesthesie bij arbeid : positieve invloed op kwaliteit van analgesie door epiduraal clonidine en neostigmine bij doorbraakpijn?
    Medical condition: Combined spinal-epidural analgesia during labour
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2010-024018-71 Sponsor Protocol Number: 2010-024018-71 Start Date*: 2011-03-31
    Sponsor Name:AZIENDA UNIVERSITARIA POLICLINICO UMBERTO I DI ROMA
    Full Title: PREMEDICATION IN CHILDREN: CLONIDINE VERSUS MELATONIN
    Medical condition: HEALTHY CHILDREN UNDERGOING ELECTIVE MINOR SURGERY
    Disease:
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-000714-74 Sponsor Protocol Number: 1.0 Start Date*: 2008-07-15
    Sponsor Name:Institution of Paediatric Anaesthesia and intensiv care, Astrid Lindgren Childrens Hospital, Karolin
    Full Title: Premedication in paediatric patients: Dose finding study of clonidine administrated as nasal aerosol.
    Medical condition: Premedication prior to anaesthesia
    Disease:
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-004988-30 Sponsor Protocol Number: 23386753 Start Date*: Information not available in EudraCT
    Sponsor Name:Mater Misercordiae Hospital - Department of Anaesthesia
    Full Title: PHARMACOKINETICS AND ANALGESIC EFFICACY OF LAEVOBUPIVACAINE, FENTANYL AND CLONIDINE FOR POSTOPERATIVE PARAVERTEBRAL ANAESTHESIA.
    Medical condition: We are aiming to provide postoperative analgesia for breast surgery
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: IE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-018781-23 Sponsor Protocol Number: 2917800009 Start Date*: Information not available in EudraCT
    Sponsor Name:Top Institute Food and Nutrition
    Full Title: Diagnose of GH-deficiency: comparing the dietary-protein test with conventional Growth Hormone Stimulation Tests
    Medical condition: To investigate if there is a correlation between the peak GH concentrations after ingestion of gelatin protein and the peak GH concentrations after the two standard tests (GHST) in order to discrim...
    Disease: Version SOC Term Classification Code Term Level
    12.1 10056438 Growth hormone deficiency LLT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-004281-18 Sponsor Protocol Number: NC12547 Start Date*: 2020-08-18
    Sponsor Name:Odense University Hospital
    Full Title: Clonidine for Tourniquet-related Pain in Children (CLOTCH) -Study: A Pilot Study
    Medical condition: Pain, which occurs in relation to the use of tourniquets during limb surgery. Tourniquets are positioned on the upper part of the limb in question, inflated and thereby stops perfusion of the limb....
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10053680 Tourniquet application PT
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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