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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44381   clinical trials with a EudraCT protocol, of which   7393   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    10,987 result(s) found. Displaying page 103 of 550.
    «« First « Previous 99  100  101  102  103  104  105  106  107  Next» Last»»
    EudraCT Number: 2011-000721-77 Sponsor Protocol Number: NITRITE/AMI/4.1 Start Date*: 2011-12-13
    Sponsor Name:Barts Health NHS Trust
    Full Title: A randomised, double-blind, placebo-controlled trial assessing the safety and efficacy of intracoronary nitrite infusion during acute myocardial infarction
    Medical condition: Acute myocardial Infarction
    Disease: Version SOC Term Classification Code Term Level
    15.1 10007541 - Cardiac disorders 10028596 Myocardial infarction PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-023852-10 Sponsor Protocol Number: 18F-AV-45-020 Start Date*: 2011-10-03
    Sponsor Name:Avid Radiopharmaceuticals, Inc.
    Full Title: 18F-AV-45 Amyloid PET Imaging in Primary Progressive Aphasia
    Medical condition: Focal dementia syndromes - primary aphasia
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029205 - Nervous system disorders 10012292 Dementia of the Alzheimer's type NOS LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-023625-38 Sponsor Protocol Number: JF003 Start Date*: 2012-11-13
    Sponsor Name:Guy's and St Thomas' NHS Foundation Trust
    Full Title: Investigating the effect of Maraviroc on microbial translocation in HIV-1 infected individuals who are receiving antiretroviral therapy
    Medical condition: HIV
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10068341 HIV-1 infection LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-003304-20 Sponsor Protocol Number: OKHN1006 Start Date*: 2012-07-02
    Sponsor Name:Moorfields Eye Hospital NHS Foundation Trust
    Full Title: Randomised Controlled Trial of Intravitreal therapy with Avastin compared to Observation in Patients with Diabetic Ischaemic Macular Oedema ‘The DIME study’
    Medical condition: Ischaemic Diabetic Macular Oedema
    Disease: Version SOC Term Classification Code Term Level
    14.1 10015919 - Eye disorders 10057934 Diabetic macular edema LLT
    14.1 10015919 - Eye disorders 10012689 Diabetic retinopathy PT
    14.1 10015919 - Eye disorders 10012688 Diabetic retinal oedema PT
    14.1 10015919 - Eye disorders 10012661 Diabetic eye disease PT
    14.1 10015919 - Eye disorders 10054372 Diabetic retinal edema LLT
    14.1 10015919 - Eye disorders 10038925 Retinopathy diabetic LLT
    14.1 10015919 - Eye disorders 10057915 Diabetic macular oedema LLT
    14.1 10014698 - Endocrine disorders 10012657 Diabetic complications ophthalmic HLT
    14.1 10015919 - Eye disorders 10054109 Non-proliferative diabetic retinopathy LLT
    14.1 10014698 - Endocrine disorders 10012653 Diabetic complications HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-021257-39 Sponsor Protocol Number: PB-PG-0808-16319 Start Date*: 2011-07-26
    Sponsor Name:SWBH NHS Trust [...]
    1. SWBH NHS Trust
    2. Keele University
    Full Title: Is it clinically effective to treat arm flexor spasticity, with Botulinum toxin – type A (BoNTA) and physiotherapy, as soon as signs of abnormal muscle activity are observed? (A phase II study)
    Medical condition: Stroke.Spasticity.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2012-003343-29 Sponsor Protocol Number: RG_12-179 Start Date*: 2013-01-18
    Sponsor Name:University of Birmingham
    Full Title: Simvastatin as adjuvant therapy to correct neutrophil dysfunction in older pneumonia patients - a randomised double blind placebo controlled trial
    Medical condition: Acute episodes of Pneumonia and sepsis in older adults
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10035664 Pneumonia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-024380-41 Sponsor Protocol Number: SPON868-10 Start Date*: 2011-08-25
    Sponsor Name:Cardiff University
    Full Title: A pilot study to assess the effect of regulatory T-cell depletion on 5T4-containing MVA(TroVax®)vaccination in patients with inoperable metastatic colorectal cancer
    Medical condition: Inoperable metastatic colorectal cancer
    Disease: Version SOC Term Classification Code Term Level
    13.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10009951 Colon cancer NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-001451-35 Sponsor Protocol Number: 2006CD004 Start Date*: 2006-12-28
    Sponsor Name:South Manchester University NHS Trust
    Full Title: How does fish oil supplementation protect against atrial fibrillation following coronary artery by-pass surgery? - A cellular study.
    Medical condition: ATRIAL FIBRILLATION (AF) FOLLOWING CORONARY ARTERY BY-PASS GRAFT (CABG)SURGERY.
    Disease: Version SOC Term Classification Code Term Level
    8.1 10003658 Atrial fibrillation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-005486-13 Sponsor Protocol Number: 12-EI-0134 Start Date*: 2013-02-25
    Sponsor Name:The National Eye Institute
    Full Title: A Phase II Randomized Study to Compare Anti-VEGF Agents in the Treatment of Diabetic Macular Edema (CADME)
    Medical condition: Diabetic Macular Edema (DME)
    Disease: Version SOC Term Classification Code Term Level
    15.1 100000004853 10057934 Diabetic macular edema LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2013-000719-26 Sponsor Protocol Number: ETS6103-003 Start Date*: 2013-06-10
    Sponsor Name:e-Therapeutics plc
    Full Title: A single centre, double blind, non-inferiority study to evaluate the antidepressant activity of Viotra™ compared with amitriptyline in the treatment of major depressive disorder (MDD) in patients w...
    Medical condition: Major Depressive Disorder
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004873 10025458 Major depressive disorder, recurrent episode, moderate degree LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2013-000750-21 Sponsor Protocol Number: 12/0426 Start Date*: 2013-12-18
    Sponsor Name:University College London
    Full Title: The HALT-LTBI study: Phase IV, multi-site, unblinded, randomised trial of prophylactic daily rifampicin/isoniazid vs. weekly rifapentine/isoniazid for latent tuberculosis infection (LTBI)
    Medical condition: Latent tuberculosis infection
    Disease: Version SOC Term Classification Code Term Level
    16.1 10021881 - Infections and infestations 10065048 Latent tuberculosis PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-000181-36 Sponsor Protocol Number: FAB-CL-204 Start Date*: 2006-03-17
    Sponsor Name:Amicus Therapeutics, Inc.
    Full Title: A Phase 2, Open-Label, Multiple Dose Level, 12-Week Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of AT1001 in Female Patients with Fabry Disease
    Medical condition: Fabry disease
    Disease: Version SOC Term Classification Code Term Level
    8.1 10016016 LLT
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-000306-70 Sponsor Protocol Number: 2009/07 Start Date*: 2008-01-29
    Sponsor Name:University of Dundee
    Full Title: The effect of metformin on biomarker activity in primary breast cancer
    Medical condition: Women with histologically proven operable primary, invasive breast cancer of ≥ 1cm in size. The study will involve women from the east of Scotland.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10006190 Breast cancer invasive NOS LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-001774-24 Sponsor Protocol Number: 3574 Start Date*: 2006-09-13
    Sponsor Name:Newcastle u Tyne Hospitals NHS Trust
    Full Title: INTESTINAL MICRO-ORGANISMS IN THE PATHOGENESIS OF NASH AND THE ROLE OF MODULATION OF ENTERIC BACTERIA IN TREATMENT.
    Medical condition: Non alcoholic fatty liver disease (NAFLD)/steatohepatitis (NASH)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2006-004460-31 Sponsor Protocol Number: PRINT Start Date*: 2007-02-21
    Sponsor Name:Guy's & St Thomas' NHS Foundation Trust
    Full Title: A randomised controlled trial comparing the gonadotrophin releasing hormone (GnRH) agonist long regimen versus the GnRH agonist short regimen versus the GnRH antagonist regimen in poor responders u...
    Medical condition: Poor ovarian response in women undergoing In vitro Fertilisation (IVF) treatment.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10056204 In vitro fertilisation PT
    Population Age: Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-004461-34 Sponsor Protocol Number: 1.0 Start Date*: 2006-11-02
    Sponsor Name:University of Nottingham
    Full Title: Open label randomised trial of nicotine replacement therapy and oral smokeless tobacco (snus) in smoking cessation
    Medical condition: Smoking cessation
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10053325 Smoking cessation therapy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2004-004830-15 Sponsor Protocol Number: S241-GB-02 Start Date*: 2005-01-31
    Sponsor Name:Stiefel Laboratories Maidenhead Ltd (commonly known as Stiefel International R&D)
    Full Title: Human Repeat Insult Patch Test with Challenge
    Medical condition: Not Applicable (Healthy Volunteer Study)
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-000083-24 Sponsor Protocol Number: GCPL/RGN/02 Start Date*: 2007-06-07
    Sponsor Name:Regen Therapeutics PLC
    Full Title: A survey of efficacy of zolpidem in patients with brain injury including SPECT brain scans in selected patients
    Medical condition: Brain damage of any original cause, such as strokes, trauma, birth injury, post-viral infection.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10056389 Brain damage LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Not Authorised)
    Trial results: (No results available)
    EudraCT Number: 2006-003519-33 Sponsor Protocol Number: D1443L00003 Start Date*: 2007-01-25
    Sponsor Name:AstraZeneca UK Limited
    Full Title: RAPID - An Open-Label, Randomised, Multicentre Phase IIIb Study to Evaluate the Efficacy and Tolerability of Quetiapine IR (Immedicate Release), over 14 days, in Acute Schizophrenia / Schizoaffecti...
    Medical condition: Acute Schizophrenia and Schizoaffective Disorder
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2004-000035-28 Sponsor Protocol Number: TD-04-06 Start Date*: 2004-12-06
    Sponsor Name:Wyeth Consumer Healthcare
    Full Title: TDS-943 MAXIMUM USE TOLERANCE STUDY
    Medical condition: Relieve pain and swelling in joints, muscles
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
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    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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