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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44352   clinical trials with a EudraCT protocol, of which   7380   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    10,988 result(s) found. Displaying page 59 of 550.
    «« First « Previous 55  56  57  58  59  60  61  62  63  Next» Last»»
    EudraCT Number: 2013-004977-28 Sponsor Protocol Number: 701079.01.013 Start Date*: 2014-02-06
    Sponsor Name:Dr. Willmar Schwabe GmbH & Co. KG
    Full Title: Safety and intake effect of EPs®7630 (an extract from the roots of Pelargonium sidoides)
    Medical condition: common cold
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004862 10010106 Common cold LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2012-000478-42 Sponsor Protocol Number: 008285QM Start Date*: 2013-02-18
    Sponsor Name:Queen Mary, University of London
    Full Title: NEPTUNE: A Randomised Phase II Study of Neoadjuvant TAK-700 and Leuprorelin Acetate versus Surgery Alone in Intermediate and High Risk Clinically Localized Prostate Cancer
    Medical condition: High or Intermediate Risk, Untreated, Clinically Localised Prostate Cancer
    Disease:
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-002457-30 Sponsor Protocol Number: 13.0099 Start Date*: 2013-09-13
    Sponsor Name:St George's University of London
    Full Title: An open label randomised controlled trial investigating the effect of donepezil on regional cerebral blood flow in adults with aneurysmal subarachnoid haemorrhage.
    Medical condition: Aneurysmal subarachnoid haemorrhage Cerebral vasospasm Ischaemic stroke
    Disease: Version SOC Term Classification Code Term Level
    16.0 10029205 - Nervous system disorders 10047164 Vasospasm cerebral LLT
    16.0 10029205 - Nervous system disorders 10061256 Ischaemic stroke PT
    16.0 10029205 - Nervous system disorders 10055845 Haemorrhage subarachnoid LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-003563-58 Sponsor Protocol Number: PET_HX4_01 Start Date*: 2013-11-11
    Sponsor Name:Nottingham University Hospitals NHS Trust
    Full Title: A Phase II, single-centre exploratory study to assess the value of hypoxia imaging with [18F]HX4 PET/CT in predicting outcome for patients with squamous cell carcinoma of head and neck and non-smal...
    Medical condition: Patients with either: (a) non small cell lung carcinoma, or (b) squamous cell carcinoma of the upper aerodigestive tract Patients with distant metastases will not be included.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10060121 Squamous cell carcinoma of head and neck PT
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10061873 Non-small cell lung cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2013-001420-19 Sponsor Protocol Number: CSLCT-TIV-13-84 Start Date*: 2013-05-23
    Sponsor Name:bioCSL Pty Ltd
    Full Title: A Phase IV, Single-Centre, Open-label Study to Evaluate the Immunogenicity and Safety of the 2013/2014 Formulation of a bioCSL split virion, inactivated influenza vaccine in Healthy Volunteers aged...
    Medical condition: Influenza, human
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2013-004860-78 Sponsor Protocol Number: P1209NY Start Date*: 2014-05-09
    Sponsor Name:G. Pohl-Boskamp GmbH & Co. KG
    Full Title: A randomised, active-controlled, observer-blind, non-inferiority study to investigate the efficacy, safety and tolerability of a local treatment with dimeticone-based pediculicides in head lice inf...
    Medical condition: Pediculosis capitis
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004862 10019199 Head pediculosis LLT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2012-004891-20 Sponsor Protocol Number: PNV117270 Start Date*: 2013-09-06
    Sponsor Name:GlaxoSmithKline Research and Development Ltd
    Full Title: A randomised, double-blind (sponsor-unblind), placebo controlled, cross-over study to investigate the efficacy, effect on cough reflex sensitivity, safety, tolerability and pharmacokinetics of inha...
    Medical condition: chronic idiopathic cough
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004855 10066656 Chronic cough LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2012-004900-37 Sponsor Protocol Number: DC05/RUP/I/13 Start Date*: 2012-11-20
    Sponsor Name:J. Uriach y Compañía, S.A.
    Full Title: A Phase I, Randomised, Double-blind, Placebo-controlled, Parallel group study to assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of oral Rupatadine in Healthy Japanese Subjec...
    Medical condition: This is a Phase I study in helathy subjects. No condition is being treated. The IMP is approved for symptomatic treatment of allergic rhinitis and urticaria in adults and adolescents (over 12 yea...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-003200-39 Sponsor Protocol Number: 13/0077 Start Date*: 2014-04-01
    Sponsor Name:University College London
    Full Title: A phase II, single centre, randomised, placebo-controlled, 3-part trial to assess the safety, tolerability and efficacy of Zibotentan in patients with renal disease secondary to scleroderma
    Medical condition: Renal complications of systemic sclerosis (scleroderma renal crisis and chronic kidney disease).
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004857 10064848 Chronic kidney disease LLT
    16.1 10028395 - Musculoskeletal and connective tissue disorders 10061087 Connective tissue disorder PT
    16.1 10028395 - Musculoskeletal and connective tissue disorders 10018124 Generalized scleroderma LLT
    16.1 100000004857 10069339 Acute kidney injury LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-006127-12 Sponsor Protocol Number: PNB/CPS 02 2007 Start Date*: 2008-01-22
    Sponsor Name:PharmaNeuroBoost N.V. (PNB)
    Full Title: Pipamperone/Citalopram (PipCit) versus Citalopram in the Treatment of Major Depressive disorder (MDD)
    Medical condition: Major Depressive Disorder (MDD)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-004785-98 Sponsor Protocol Number: OVG2008/5 Start Date*: 2008-12-22
    Sponsor Name:University of Oxford
    Full Title: An observational study of children immunised in infancy against hepatitis B virus, evaluating the persistence of immunity and the immune response to a scheduled booster dose of hepatitis B vaccine
    Medical condition: The intended application of Engerix B is active immunisation against Hepatitis B virus infection caused by all known subtypes in non immune subjects.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10052552 Hepatitis B virus LLT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-004803-78 Sponsor Protocol Number: 1.1 Start Date*: 2009-03-20
    Sponsor Name:Imperial College London
    Full Title: Effectiveness of Transtympanic Steroids in unilateral Ménière's disease: a Randomised Controlled Double-Blind Trial
    Medical condition: refractory unilateral Meniere's disease
    Disease: Version SOC Term Classification Code Term Level
    9.1 10000641 Active Meniere's disease, cochleovestibular LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-013791-49 Sponsor Protocol Number: RHM MED 0879 Start Date*: 2009-09-23
    Sponsor Name:Southampton Universities Hospital Trust
    Full Title: Safety and Efficacy of parenteral KGF in moderate asthma subjects
    Medical condition: Asthma
    Disease: Version SOC Term Classification Code Term Level
    12 10003553 Asthma PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2010-022072-31 Sponsor Protocol Number: R5242A789 Start Date*: 2013-04-15
    Sponsor Name:RJAH Orthopaedic Hospital
    Full Title: Autologous Cell Therapy for Osteoarthritis: An evaluation of the safety and efficacy of autologous transplantation of articular chondrocytes and/or bone marrow-derived stromal cells to repair chond...
    Medical condition: osteochondral defects of the knee (early osteoarthritis)
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004859 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2010-020943-10 Sponsor Protocol Number: GA10/9312 Start Date*: 2011-03-16
    Sponsor Name:University of Leeds
    Full Title: A randomised controlled trial of eicosapentaenoic acid (EPA) and/or aspirin for colorectal adenoma (or polyp) prevention during colonoscopic surveillance in the NHS Bowel Cancer Screening Programme...
    Medical condition: colorectal adenoma (polyp)
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004864 10048841 Bowel cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-012621-12 Sponsor Protocol Number: R&D2008GR03 Start Date*: 2009-08-06
    Sponsor Name:University of Dundee
    Full Title: Maximising physical function in later life: a 2 centre randomised trial of progressive resistance exercise training in combination with ACE inhibition
    Medical condition: Age related decline in muscle function (sarcopenia)
    Disease: Version SOC Term Classification Code Term Level
    13.1 10028395 - Musculoskeletal and connective tissue disorders 10063024 Sarcopenia PT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-001568-35 Sponsor Protocol Number: RGHT000559 Start Date*: 2008-06-24
    Sponsor Name:BELFAST HEALTH & SOCIAL CARE TRUST
    Full Title: Comparison of fascia iliac compartment block with conventional sedation to facilitate the positioning of patients with fractured neck of femur for spinal anaesthesia and the effect of nerve blockad...
    Medical condition: Investigation of the use a Fascia Iliaca nerve blockade for both positioning for spinal anaesthesia and postoperative analgesia in patients undergoing operative repair of fractured neck of femur.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-002836-18 Sponsor Protocol Number: EPA/POL/03 Start Date*: 2006-10-09
    Sponsor Name:S.L.A. Pharma (UK) Ltd
    Full Title: A Two-Arm Chemoprevention Trial in Familial Adenomatous Polyposis Coli Patients Using the Purified Free Fatty Acid, Eicosapentaenoic Acid.
    Medical condition: Familial adenomatous polyposis (FAP)
    Disease: Version SOC Term Classification Code Term Level
    8.1 10059327 Familial adenomatous polyposis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-002837-19 Sponsor Protocol Number: RD-5103-037-05 Start Date*: 2007-04-16
    Sponsor Name:DERBY HOSPITALS NHS FOUNDATION TRUST
    Full Title: A DOUBLE BLIND PLACEBO CONTROLLED TRIAL OF TERLIPRESSIN IN THE MANAGEMENT OF SEVERE ALCOHOLIC HEPATITIS – A PRELIMINARY STUDY
    Medical condition: Severe alcoholic hepatitis as judged by a Maddrey score >32
    Disease: Version SOC Term Classification Code Term Level
    8.1 10001624 Alcoholic hepatitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-020048-36 Sponsor Protocol Number: HGT-HIT-045 Start Date*: 2011-01-31
    Sponsor Name:Shire HGT, Inc
    Full Title: A Phase I/II, Randomized, Safety and Ascending Dose Ranging Study of Intrathecal Idursulfase-IT administered in conjunction with intravenous Elaprase in Pediatric Patients with Hunter Syndrome and ...
    Medical condition: Treatment of Hunter syndrome and cognitive impairment
    Disease: Version SOC Term Classification Code Term Level
    14.1 10010331 - Congenital, familial and genetic disorders 10056889 Mucopolysaccharidosis II PT
    Population Age: Children, Adolescents, Under 18 Gender: Male
    Trial protocol: GB (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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