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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44381   clinical trials with a EudraCT protocol, of which   7393   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    10,987 result(s) found. Displaying page 59 of 550.
    «« First « Previous 55  56  57  58  59  60  61  62  63  Next» Last»»
    EudraCT Number: 2007-006127-12 Sponsor Protocol Number: PNB/CPS 02 2007 Start Date*: 2008-01-22
    Sponsor Name:PharmaNeuroBoost N.V. (PNB)
    Full Title: Pipamperone/Citalopram (PipCit) versus Citalopram in the Treatment of Major Depressive disorder (MDD)
    Medical condition: Major Depressive Disorder (MDD)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-004785-98 Sponsor Protocol Number: OVG2008/5 Start Date*: 2008-12-22
    Sponsor Name:University of Oxford
    Full Title: An observational study of children immunised in infancy against hepatitis B virus, evaluating the persistence of immunity and the immune response to a scheduled booster dose of hepatitis B vaccine
    Medical condition: The intended application of Engerix B is active immunisation against Hepatitis B virus infection caused by all known subtypes in non immune subjects.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10052552 Hepatitis B virus LLT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-004803-78 Sponsor Protocol Number: 1.1 Start Date*: 2009-03-20
    Sponsor Name:Imperial College London
    Full Title: Effectiveness of Transtympanic Steroids in unilateral Ménière's disease: a Randomised Controlled Double-Blind Trial
    Medical condition: refractory unilateral Meniere's disease
    Disease: Version SOC Term Classification Code Term Level
    9.1 10000641 Active Meniere's disease, cochleovestibular LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-013791-49 Sponsor Protocol Number: RHM MED 0879 Start Date*: 2009-09-23
    Sponsor Name:Southampton Universities Hospital Trust
    Full Title: Safety and Efficacy of parenteral KGF in moderate asthma subjects
    Medical condition: Asthma
    Disease: Version SOC Term Classification Code Term Level
    12 10003553 Asthma PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2010-022072-31 Sponsor Protocol Number: R5242A789 Start Date*: 2013-04-15
    Sponsor Name:RJAH Orthopaedic Hospital
    Full Title: Autologous Cell Therapy for Osteoarthritis: An evaluation of the safety and efficacy of autologous transplantation of articular chondrocytes and/or bone marrow-derived stromal cells to repair chond...
    Medical condition: osteochondral defects of the knee (early osteoarthritis)
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004859 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2010-020943-10 Sponsor Protocol Number: GA10/9312 Start Date*: 2011-03-16
    Sponsor Name:University of Leeds
    Full Title: A randomised controlled trial of eicosapentaenoic acid (EPA) and/or aspirin for colorectal adenoma (or polyp) prevention during colonoscopic surveillance in the NHS Bowel Cancer Screening Programme...
    Medical condition: colorectal adenoma (polyp)
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004864 10048841 Bowel cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-012621-12 Sponsor Protocol Number: R&D2008GR03 Start Date*: 2009-08-06
    Sponsor Name:University of Dundee
    Full Title: Maximising physical function in later life: a 2 centre randomised trial of progressive resistance exercise training in combination with ACE inhibition
    Medical condition: Age related decline in muscle function (sarcopenia)
    Disease: Version SOC Term Classification Code Term Level
    13.1 10028395 - Musculoskeletal and connective tissue disorders 10063024 Sarcopenia PT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-001568-35 Sponsor Protocol Number: RGHT000559 Start Date*: 2008-06-24
    Sponsor Name:BELFAST HEALTH & SOCIAL CARE TRUST
    Full Title: Comparison of fascia iliac compartment block with conventional sedation to facilitate the positioning of patients with fractured neck of femur for spinal anaesthesia and the effect of nerve blockad...
    Medical condition: Investigation of the use a Fascia Iliaca nerve blockade for both positioning for spinal anaesthesia and postoperative analgesia in patients undergoing operative repair of fractured neck of femur.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-002836-18 Sponsor Protocol Number: EPA/POL/03 Start Date*: 2006-10-09
    Sponsor Name:S.L.A. Pharma (UK) Ltd
    Full Title: A Two-Arm Chemoprevention Trial in Familial Adenomatous Polyposis Coli Patients Using the Purified Free Fatty Acid, Eicosapentaenoic Acid.
    Medical condition: Familial adenomatous polyposis (FAP)
    Disease: Version SOC Term Classification Code Term Level
    8.1 10059327 Familial adenomatous polyposis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-002837-19 Sponsor Protocol Number: RD-5103-037-05 Start Date*: 2007-04-16
    Sponsor Name:DERBY HOSPITALS NHS FOUNDATION TRUST
    Full Title: A DOUBLE BLIND PLACEBO CONTROLLED TRIAL OF TERLIPRESSIN IN THE MANAGEMENT OF SEVERE ALCOHOLIC HEPATITIS – A PRELIMINARY STUDY
    Medical condition: Severe alcoholic hepatitis as judged by a Maddrey score >32
    Disease: Version SOC Term Classification Code Term Level
    8.1 10001624 Alcoholic hepatitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-020048-36 Sponsor Protocol Number: HGT-HIT-045 Start Date*: 2011-01-31
    Sponsor Name:Shire HGT, Inc
    Full Title: A Phase I/II, Randomized, Safety and Ascending Dose Ranging Study of Intrathecal Idursulfase-IT administered in conjunction with intravenous Elaprase in Pediatric Patients with Hunter Syndrome and ...
    Medical condition: Treatment of Hunter syndrome and cognitive impairment
    Disease: Version SOC Term Classification Code Term Level
    14.1 10010331 - Congenital, familial and genetic disorders 10056889 Mucopolysaccharidosis II PT
    Population Age: Children, Adolescents, Under 18 Gender: Male
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-005304-93 Sponsor Protocol Number: ZOL40/02 Start Date*: 2009-02-13
    Sponsor Name:North Bristol Trust
    Full Title: A Randomised Control Trial To Evaluate Whether Zoledronate Prevents Bone Loss In Acute Exacerbations Of Multiple Sclerosis
    Medical condition: Bone loss in patients with Multiple Sclerosis (MS) who require large short term doses of methylprednisolone for exacerbations of their disease.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10048393 Multiple sclerosis relapse LLT
    9.1 10065687 Bone loss LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-023355-29 Sponsor Protocol Number: PO1425 Start Date*: 2011-05-18
    Sponsor Name:Papworth Hospital NHS Foundation Trust
    Full Title: Tyrosine kinase Inhibitors in DysplAsia of Lung epithelium Study 1
    Medical condition: High grade dysplasia of the bronchoepithelium
    Disease: Version SOC Term Classification Code Term Level
    13.1 10038738 - Respiratory, thoracic and mediastinal disorders 10057004 Bronchial dysplasia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-009096-35 Sponsor Protocol Number: QGUY/2008/TA-270/-01 Start Date*: 2009-03-12
    Sponsor Name:Activus Pharma Co., Ltd
    Full Title: An open-label, 28-day multiple dose pilot study to evaluate the effects on lung oxidative stress, safety and pharmacokinetics of TA-270 in patients with chronic obstructive pulmonary disease (COPD).
    Medical condition: Chronic obstructive pulmonary disease. ( COPD)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10010952 COPD LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-009154-25 Sponsor Protocol Number: omalizumab/2009/01 Start Date*: 2009-07-07
    Sponsor Name:King's College London [...]
    1. King's College London
    2. Guy's and St.Thomas' NHS Foundation Trust
    Full Title: The effect of a humanised monoclonal anti-IgE antibody (omalizumab) on disease control and bronchial mucosal inflammation in non-atopic (“intrinsic”) asthma
    Medical condition: Asthma
    Disease: Version SOC Term Classification Code Term Level
    16.1 10038738 - Respiratory, thoracic and mediastinal disorders 10003553 Asthma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-022472-31 Sponsor Protocol Number: Lidocaine1 Start Date*: 2010-12-23
    Sponsor Name:University Hospital of South Manchester
    Full Title: The effect of Lidocaine and its Delivery in Patients with Chronic Cough
    Medical condition: Chronic Cough
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-001769-27 Sponsor Protocol Number: CHI0465 Start Date*: 2008-09-29
    Sponsor Name:Southampton University Hospital Trust
    Full Title: Microbiological assessment of prophylactic ciprofloxacin therapy for children with cystic fibrosis during viral respiratory viral infection to prevent Pseudomonas aeruginosa colonisation – a random...
    Medical condition: Cystic Fibrosis Specifically the trial will include children aged 2-14 years with a diagnosis of cystic fibrosis and not chronically infected with pseudomonas aeruginosa in their lungs.
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2005-000989-39 Sponsor Protocol Number: STRU -02-05 Start Date*: 2005-09-23
    Sponsor Name:Guy's & St Thomas NHS foundation Trust
    Full Title: A Single Centre, double blind, placebo controlled, randomised trial to evaluate the efficacy and safety of Simvastatin in the treatment of Psoriasis.
    Medical condition: Psoriasis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-014758-14 Sponsor Protocol Number: 201177 Start Date*: 2010-05-13
    Sponsor Name:West Middlesex University Hospital
    Full Title: Does nebulised hypertonic (3%) saline reduce the duration of hospital admission in infants with bronchiolitis?
    Medical condition: Viral bronchiolitis (in infants aged under 1yr old)
    Disease: Version SOC Term Classification Code Term Level
    12-1 10038718 (Respiratory syncytial virus) bronchiolitis LLT
    Population Age: Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-014375-50 Sponsor Protocol Number: YDH/09/01 Start Date*: 2010-02-01
    Sponsor Name:Yeovil District Hospital
    Full Title: Comparison of the Efficacy of Thoracic Epidural Analgesia and a Local Anaesthetic Wound Infusion Catheter after Laparoscopic Colectomy within the Enhanced Recovery Programme : a pilot RCT
    Medical condition: Patients undergoing elective laparoscopic colectomy for either benign or malignant tumour in the right or left colon with intention to cure.
    Disease: Version SOC Term Classification Code Term Level
    12 10009944 colon cancer LLT
    12 10009946 Colon Cancer Duke's A LLT
    12 10009947 Colon Cancer Duke's B1 LLT
    12 10009948 Colon Cancer Duke's B2 LLT
    12 10009949 Colon Cancer Duke's C LLT
    12 10009952 Colon Cancer Recurrent LLT
    12 10009953 Colon Cancer Stage I LLT
    12 10009954 Colon Cancer Stage II LLT
    12 10009955 Colon Cancer Stage III LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
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    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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