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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44346   clinical trials with a EudraCT protocol, of which   7374   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    10,988 result(s) found. Displaying page 87 of 550.
    «« First « Previous 83  84  85  86  87  88  89  90  91  Next» Last»»
    EudraCT Number: 2017-004539-36 Sponsor Protocol Number: 16NC06 Start Date*: 2020-05-19
    Sponsor Name:Great Ormond Street Hospital for Children NHS Foundation Trust
    Full Title: Study of Montelukast In Children with Sickle Cell Disease (SMILES)
    Medical condition: Sleep-disordered breathing
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004855 10078294 Obstructive sleep apnoea hypopnoea syndrome LLT
    21.0 100000004855 10040977 Sleep apnoea LLT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2020-000282-16 Sponsor Protocol Number: MAST Start Date*: Information not available in EudraCT
    Sponsor Name:Cambridge University Hospitals NHS Foundation Trust and The University of Cambridge
    Full Title: Pharmacological management of seizures post traumatic brain injury (MAST)
    Medical condition: Post traumatic seizures following traumatic brain injury
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029205 - Nervous system disorders 10039911 Seizures (incl subtypes) HLGT
    Population Age: Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2015-005676-25 Sponsor Protocol Number: AC16025 Start Date*: 2016-08-31
    Sponsor Name:University of Edinburgh [...]
    1. University of Edinburgh
    2. NHS Lothian
    Full Title: Sensing using Neutrophil Activation Probe on the Intensive Therapy Unit
    Medical condition: Critical illness requiring ventilation
    Disease: Version SOC Term Classification Code Term Level
    20.0 10018065 - General disorders and administration site conditions 10077264 Critical illness PT
    20.0 100000004865 10003541 Assisted ventilation LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2012-001889-14 Sponsor Protocol Number: Bubble2012 Start Date*: 2012-10-15
    Sponsor Name:Cambridge University Hospitals NHS Foundation Trust
    Full Title: MicroBubble detection and Ultrasound guided Biopsy of axillary Lymph nodes in patients with Early breast cancer.
    Medical condition: Diagnosis of lymph node metastases in patients with newly diagnosed breast cancer.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10057654 Breast cancer female PT
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10006203 Breast cancer stage unspecified LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-001900-39 Sponsor Protocol Number: 11/0475 Start Date*: 2012-11-01
    Sponsor Name:University College London
    Full Title: A multicentre randomised phase II clinical trial of Inotuzumab Ozogamicin plus Rituximab and CVP (IO-R-CVP) versus Gemcitabine plus Rituximab and CVP (Gem-R-CVP) for the first line treatment of pat...
    Medical condition: Diffuse large B cell lymphoma
    Disease: Version SOC Term Classification Code Term Level
    21.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10012818 Diffuse large B-cell lymphoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2013-001922-24 Sponsor Protocol Number: 120541 Start Date*: 2013-07-12
    Sponsor Name:University College London (UCL)
    Full Title: The effect of remote ischaemic preconditioning and glyceryl trinitrate on peri-operative myocardial injury in cardiac bypass surgery patients (ERIC-GTN study)- a four arm randomised controlled trial
    Medical condition: We are investigating the phenomenon of ischaemic-reperfusion injury. Reperfusion of the ischaemic myocardium is known to cause further myocardial damage. We wish to investigate the phenomenon of Re...
    Disease: Version SOC Term Classification Code Term Level
    16.0 10007541 - Cardiac disorders 10051624 Myocardial reperfusion injury PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-000209-22 Sponsor Protocol Number: 12GA029 Start Date*: 2013-06-07
    Sponsor Name:Research and Development Nottingham University Hospital
    Full Title: A pilot study to assess the efficacy of intravenous iron isomaltoside 1000 (Monofer®) in the management of anaemia associated with the palliative management of upper gastrointestinal adenocarcinoma
    Medical condition: The medical condition to be investigated is anaemia in patients with oesophageal or gastric cancer planned to undergo palliative chemotherapy.
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004851 10002062 Anaemia iron deficiency LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-004936-75 Sponsor Protocol Number: EVOLUTION Start Date*: 2012-05-29
    Sponsor Name:Cambridge University Hospitals NHS Foundation Trust and University of Cambridge
    Full Title: An Evaluation of Losmapimod in patients with Chronic Obstructive Pulmonary Disease (COPD) with systemic inflammation stratified using fibrinogen (EVOLUTION)
    Medical condition: The trial team will be looking at patients with Chronic Obstructive Pulmonary Disease and how inflammation affects them.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10038738 - Respiratory, thoracic and mediastinal disorders 10009033 Chronic obstructive pulmonary disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2012-004117-14 Sponsor Protocol Number: SPON1037-11 Start Date*: 2013-04-15
    Sponsor Name:Cardiff University
    Full Title: A feasibility study to inform the design of a randomised controlled trial to identify the most clinically and cost effective length of Anticoagulation with Low molecular weight heparin In the treat...
    Medical condition: Cancer Associated Thrombosis (CAT). Venous thromboembolism (VTE). Deep vein thrombosis (DVT). Pulmonary embolus (PE).
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004865 10049910 Thromboembolism prophylaxis LLT
    14.1 100000004866 10066899 Venous thromboembolism LLT
    14.1 100000004865 10013880 DVT prophylaxis LLT
    14.1 100000004855 10037380 Pulmonary embolus LLT
    14.1 100000004866 10043566 Thromboembolism LLT
    14.1 100000004855 10037436 Pulmonary thromboembolism LLT
    14.1 100000004865 10049909 Venous thromboembolism prophylaxis LLT
    14.1 100000004866 10013877 DVT LLT
    14.1 100000004866 10013878 DVT of calf LLT
    14.1 100000004866 10013879 DVT of legs LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-004132-33 Sponsor Protocol Number: D1050304 Start Date*: 2013-05-02
    Sponsor Name:Sunovion Pharmaceuticals Inc.
    Full Title: A Randomized, 6-Week, Double-Blind, Placebo-Controlled, Flexible-Dose, Parallel-Group Study of Lurasidone for the Treatment of Major Depressive Disorder with Mixed Features (Protocol No D1050304)
    Medical condition: Major Depressive Disorder (MDD)
    Disease: Version SOC Term Classification Code Term Level
    15.1 10037175 - Psychiatric disorders 10012378 Depression PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-006486-88 Sponsor Protocol Number: Modafinil/lung/01 Start Date*: 2009-03-17
    Sponsor Name:University of Oxford
    Full Title: Modafinil for the treatment of fatigue in lung cancer: a multicentre, randomised, double-blinded, placebo-controlled trial
    Medical condition: The symptom of fatigue in patients with non-small cell lung cancer
    Disease: Version SOC Term Classification Code Term Level
    14.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10029514 Non-small cell lung cancer NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-018878-21 Sponsor Protocol Number: SSAT036 Start Date*: 2010-08-16
    Sponsor Name:St Stephen's AIDS Trust
    Full Title: A phase III, open-label, single centre, single-arm, pilot study to assess the feasibility of switching, individuals receiving efavirenz with continuing Central Nervous System (CNS) toxicity, to ral...
    Medical condition: HIV
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-003064-47 Sponsor Protocol Number: CUDC-101-104 Start Date*: 2012-12-11
    Sponsor Name:Curis, Inc.
    Full Title: A Phase 1 open-label study to investigate the pharmacodynamics, metabolomics and pharmacokinetics of CUDC-101 in subjects with HER2 positive invasive breast cancer.
    Medical condition: HER2 positive breast cancer
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10065430 HER-2 positive breast cancer LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2012-002483-27 Sponsor Protocol Number: PKB116611 Start Date*: 2012-11-07
    Sponsor Name:Accenture
    Full Title: An Open-Label Phase I/II Study of GSK2110183 in Combination with Carboplatin and Paclitaxel in Subjects with Platinum-Resistant Ovarian Cancer
    Medical condition: Ovarian Cancer
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004864 10033130 Ovarian cancer NOS LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-005046-37 Sponsor Protocol Number: COUGAR-02 Start Date*: 2007-12-28
    Sponsor Name:Cambridge University Hospitals NHS Foundation Trust
    Full Title: COUGAR-02: A randomised phase III study of docetaxel vs active symptom control in patients with relapsed oesophago-gastric adenocarcinoma
    Medical condition: Advanced oesophago-gastric cancer which has previously been treated with a platinum and fluoropyrimidine based combination
    Disease: Version SOC Term Classification Code Term Level
    13.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10017758 Gastric cancer PT
    13.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10001173 Adenocarcinoma of esophagus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-011529-15 Sponsor Protocol Number: GHB-CS04, VIE-CS-002 Start Date*: 2010-05-26
    Sponsor Name:AVIR Green Hills Biotechnology Research Development Trade AG
    Full Title: A Phase II Prospective, Randomised, Double-Blind, Placebo-Controlled Study to Assess the Efficacy of the Influenza Vaccine GHB11L1 Administered Intranasally Against a Controlled Influenza Virus Cha...
    Medical condition: Prophylaxis of Influenza A (H1N1) infection.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10022000 Influenza LLT
    Population Age: Adults Gender: Male
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2011-004780-75 Sponsor Protocol Number: M11-427 Start Date*: 2012-06-22
    Sponsor Name:AbbVie Deutschland GmbH & Co. KG
    Full Title: Long-Term Safety and Tolerability of ABT-126 in Subjects with Mild-to-Moderate Alzheimer’s Disease: An Open-Label Extension Study for Subjects Completing Study M10-985.
    Medical condition: Mild-to-moderate Alzheimer's Disease
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004852 10001896 Alzheimer's disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-003608-11 Sponsor Protocol Number: RG_12-125 Start Date*: 2014-02-20
    Sponsor Name:University of Birmingham
    Full Title: IciCLLe: Assessment of the Mechanism of Action of Ibrutinib (PCI-32765) in B-cell Receptor Pathway Inhibition in CLL.
    Medical condition: Chronic Lymphocytic leukaemia
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004864 10009310 CLL LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2011-000677-31 Sponsor Protocol Number: STH15216 Start Date*: 2011-09-16
    Sponsor Name:Sheffield Teaching Hospitals NHS Foundation Trust
    Full Title: Testosterone Replacement in Young Male cancer Survivors
    Medical condition: Borderline low levels of testosterone in male cancer survivors who have previously had leukaemia, lymphoma or testicular cancer.
    Disease: Version SOC Term Classification Code Term Level
    14.0 10022891 - Investigations 10047900 Weight loss LLT
    Population Age: Adults Gender: Male
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-006433-28 Sponsor Protocol Number: RG_08_082_a02 Start Date*: 2009-01-20
    Sponsor Name:University of Birmingham
    Full Title: Rapid reduction versus abrupt quitting for smokers who want to stop soon: a randomised controlled non-inferiority trial.
    Medical condition: Smoking and nicotine addiction.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10056478 Nicotine addiction LLT
    9.1 10056484 Nicotine craving LLT
    9.1 10057852 Nicotine dependence LLT
    9.1 10008374 Cessation of smoking LLT
    9.1 10053325 Smoking cessation therapy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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