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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44381   clinical trials with a EudraCT protocol, of which   7393   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    26,035 result(s) found. Displaying page 216 of 1,302.
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    EudraCT Number: 2006-003014-18 Sponsor Protocol Number: TEO-NEF-01 Start Date*: 2012-03-05
    Sponsor Name:Vicente Barrio Lucia
    Full Title: Double blind randomized controlled clinical trial to evaluate the efficacy and safety of theophyline in the prevention of nephrotoxicity associated with cisplatin in oncology
    Medical condition: Eficacia del tratamiento con teofilina para evitar el descenso del 25 %, estimado en el grupo placebo del filtrado glomerular medido con EDTA-Cr51 en pacientes oncológicos bajo tratamiento quimiote...
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10007096 Cancer of lung LLT
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10007107 Cancer of ovary LLT
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10043360 Testis cancer (excl germ cell) LLT
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10005003 Bladder cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-003355-12 Sponsor Protocol Number: 12/02/2005v1 Start Date*: 2005-09-06
    Sponsor Name:University hospitals of Leicester NHS Trust
    Full Title: A prospective randomised trial in order to determine the benefit of preoperative oral iron supplementation for patients undergoing elective colorectal cancer resection
    Medical condition: Colorectal cancer
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-003374-24 Sponsor Protocol Number: OP-2005-01 Start Date*: 2005-09-12
    Sponsor Name:OPOCRIN S.P.A.
    Full Title: A phase 2, controlled, multi-center pilot study to evaluate the efficacy and safety of Deligoparin in subjects with retinal vein occlusion of recent onset.
    Medical condition: Treatment of retinal vein occlusion.
    Disease: Version SOC Term Classification Code Term Level
    6.1 10038907 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-003156-35 Sponsor Protocol Number: EXPSY 0105 Start Date*: 2005-12-01
    Sponsor Name:Department of Psychiatry and Psychotherapy (Cologne)
    Full Title: Efficacy and tolerability of Ziprasidone vs. Clozapine in the treatment of dually diagnosed (DD-) patients with schizophrenia and cannabis use disorder: A randomised study
    Medical condition: Patients with schizophrenia and cannabis abuse/dependency will be randomized to ziprasidone or clozapine treatment. Dose of medication and frequency of administration will be flexible and adjustab...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-001324-13 Sponsor Protocol Number: 2007CV27 Start Date*: 2007-05-23
    Sponsor Name:Research and Innovation Services, University of Dundee
    Full Title: Does Vitamin D improve markers of vascular health in stroke patients?
    Medical condition: Stroke (Ischaemic and haemorrhagic)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10023027 Ischaemic stroke NOS LLT
    9.1 10048863 Hemorrhagic stroke LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-004372-20 Sponsor Protocol Number: 1.1(UK) Start Date*: 2006-01-04
    Sponsor Name:Oxford Radcliffe Hospitals NHS Trust
    Full Title: A randomised, prospective,open-label, multi-centre study comparing the efficacy and safety of conversion to Sirolimus in stable renal transplant recipients with a cutaneous squamous cell carcinoma.
    Medical condition: Cutaneous squamous cell carcinoma after kidney transplantation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-006803-35 Sponsor Protocol Number: CABF656A2201 Start Date*: 2008-02-21
    Sponsor Name:NOVARTIS FARMA
    Full Title: An open-label, randomized, multicenter, active-controlled, dose-ranging study to evaluate the safety and efficacy of albinterferon alfa-2b administered every 4 weeks plus ribavirin in interferon al...
    Medical condition: CHONIC HEPATITIS C
    Disease: Version SOC Term Classification Code Term Level
    9.1 10019744 Hepatitis C LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-006816-31 Sponsor Protocol Number: P060104 Start Date*: Information not available in EudraCT
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title: Effet du mazindol sur le Trouble Déficit de l'Attention/Hyperactivité chez l'enfant : étude prospective pilote (phase II) d'efficacité, de tolérance et de pharmacocinétique
    Medical condition: Enfants de 6 à 12 ans présentant un TDAH et suivi dans le Service de Psychopathologie de l'Enfant et de l'Adolescent de l'Hôpital Robert Debré
    Disease: Version SOC Term Classification Code Term Level
    8.1 10003736 Trouble Déficit de l'Attention/Hyperactivité PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-000669-21 Sponsor Protocol Number: ML18243 Start Date*: 2005-04-26
    Sponsor Name:ROCHE
    Full Title: Pilot study of HIV Viral slope in naive patients treated with Enfuvirtide (ENF) based therapy compared to current standard treatment.
    Medical condition: advanced HIV management
    Disease: Version SOC Term Classification Code Term Level
    6.1 10000565 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2005-000671-17 Sponsor Protocol Number: 3163 K1-200-WW Start Date*: 2005-10-05
    Sponsor Name:Wyeth Research Division of Wyeth Pharmaceuticals Inc., Clinical Research and Development
    Full Title: A Safety and Efficacy Dose-Ranging Study of GAP-486 in Subjects With Nonsustained Ventricular Tachycardia and Acute Ischemia
    Medical condition: Subjects with coronary artery disease or left ventricular dysfunction experiencing an acute coronary syndrome with non-life-threatening ventricular arrhythmias.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Prematurely Ended) GB (Prematurely Ended) SE (Prematurely Ended) DK (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2004-005252-14 Sponsor Protocol Number: KAI-9803-001 Start Date*: 2005-04-21
    Sponsor Name:KAI Pharmaceuticals Incorporated
    Full Title: Direct Inhibition of δ Protein Kinase C Enzyme to Limit Total Infarct Size in Acute Myocardial Infarction (DELTA MI): Intracoronary KAI-9803 for Injection as an Adjunct to Primary Percutaneous Coro...
    Medical condition: Acute myocardial infarction with ST elevation
    Disease: Version SOC Term Classification Code Term Level
    7.1 10000891 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) CZ (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2004-005275-42 Sponsor Protocol Number: 1140 Start Date*: 2005-03-21
    Sponsor Name:AZIENDA OSPEDALIERA ISTITUTI OSPITALIERI DI VERONA
    Full Title: Study on the effect of r-hGH in combination with bisphosphonate treatment on bone metabolism in Osteogenesis Imperfecta
    Medical condition: Osteogenesis Imperfecta
    Disease: Version SOC Term Classification Code Term Level
    6.1 10010331 SOC
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-004304-12 Sponsor Protocol Number: 2260/2006 Start Date*: 2007-09-25
    Sponsor Name:AZIENDA OSPEDALIERA PISANA
    Full Title: Pilot study, randomised, open-label, monocentre, case vs control study to assess the effect of topically and parenterally Heparin administration treatment in superficial and deep second grade bu...
    Medical condition: Superficial and deep second degree burns.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10006802 Burns second degree LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-003742-18 Sponsor Protocol Number: 1208.10 Start Date*: 2005-05-10
    Sponsor Name:Boehringer Ingelheim Finland Ky
    Full Title: A ten-week, randomized, double-blind study evaluating the efficacy of Duloxetine 60 mg once daily versus placebo in outpatients with major depressive disorder and pain (EU-Pain enriched study)
    Medical condition: Depressed patients (according to DSM-IV criteria) experiencing painful physical symptoms
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) SK (Completed) CZ (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2004-003769-33 Sponsor Protocol Number: 103974, 104056 Start Date*: 2005-01-12
    Sponsor Name:GlaxoSmithKline Biologicals
    Full Title: A phase III open (partially double-blind), controlled, multicenter, multicountry primary & booster vaccination study to demonstrate the non-inferiority of the meningococcal serogroup C response of ...
    Medical condition: Three-dose primary vaccination course with a haemophilus influenzae type B and meningococcal serogroup C conjugate vaccine of infants starting between 6 to 12 weeks of age with one month interval b...
    Disease:
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-004170-25 Sponsor Protocol Number: MH-110 Start Date*: Information not available in EudraCT
    Sponsor Name:Bracco Imaging S.p.A.
    Full Title: A PHASE III, MULTI-CENTER, OPEN-LABEL STUDY TO EVALUATE SAFETY AND EFFICACY OF MULTIHANCE® AT THE DOSE OF 0.10 mmol/kg IN MAGNETIC RESONANCE IMAGING OF THE CENTRAL NERVOUS SYSTEM IN PEDIATRIC PA...
    Medical condition: imaging diagnosis of highly suspected or known brain and/or spine disease, which are known to impair the Blood Brain Barrier Function
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DE (Completed) BE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2005-003789-40 Sponsor Protocol Number: DON DF 1 Start Date*: 2005-11-11
    Sponsor Name:Pharmapnea AB
    Full Title: A randomized, four-way cross-over, double-blind, controlled study of oral donepezil (2, 5, 10 mg) in patients with moderate to severe obstructive sleep apnea.
    Medical condition: Moderate to severe obstructive sleep apnea. Males and females; aged 25 to 65 years, previously diagnosed OSA defined as an oxygen desaturation (4%) index of 15 or more per hour of sleep obtained fr...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-001635-21 Sponsor Protocol Number: VIA-2291-02 Start Date*: 2006-12-21
    Sponsor Name:VIA PHARMACEUTICALS, INC.
    Full Title: A Phase 2 Randomised, Double-blind, Placebo-controlled Study of the Effects of VIA-2291, a 5-lipoxygenase Inhibitor, on Atherosclerotic Plaque and Biomarkers of Vascular Inflammation in Patients wi...
    Medical condition: Carotid Stenosis.
    Disease: Version SOC Term Classification Code Term Level
    6.1 10047065 SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-001189-15 Sponsor Protocol Number: T-EE04-086 Start Date*: 2006-03-07
    Sponsor Name:TAP Pharmaceutical Products Inc.
    Full Title: A Phase 3 Study to Evaluate the Efficacy and Safety of TAK-390MR (60 mg QD and 90 mg QD) Compared to Placebo in Maintenance of Healing in Subjects with Healed Erosive Esophagitis
    Medical condition: Erosive esophagitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: EE (Completed) LT (Completed) CZ (Completed) GB (Prematurely Ended) LV (Completed)
    Trial results: View results
    EudraCT Number: 2009-010004-28 Sponsor Protocol Number: ACNS0331 Start Date*: 2010-04-14
    Sponsor Name:COG
    Full Title: ACNS0331 A Study Evaluating Limited Target Volume Boost Irradiation and Reduced Dose Craniospinal Radiotherapy (18.00 Gy) and Chemotherapy in Children with Newly Diagnosed Standard Risk Medulloblas...
    Medical condition: Medulloblastoom standard risk
    Disease: Version SOC Term Classification Code Term Level
    12.0 10027107 Medulloblastoma LLT
    12.0 10027107 Medulloblastoma PT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
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    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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