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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44395   clinical trials with a EudraCT protocol, of which   7407   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,395 result(s) found. Displaying page 1,071 of 2,220.
    EudraCT Number: 2017-004686-28 Sponsor Protocol Number: 14143JK-AS Start Date*: 2018-07-16
    Sponsor Name:Belfast Health and Social Care Trust (BHSCT)
    Full Title: A randomised, double-blind, placebo-controlled trial to evaluate the effect of Epstein-Barr virus suppression in chronic obstructive pulmonary disease (EViSCO trial).
    Medical condition: Epstein-Barr virus infection in patients with chronic obstructive pulmonary disease.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-017101-11 Sponsor Protocol Number: Tem/Erlo in NSCLC-Pilotstudy Start Date*: 2010-09-08
    Sponsor Name:MUW, Klinik für Innere Medizin I, Onkologie
    Full Title: A Pilot Study of Erlotinib and Temsirolimus in Patients with Advanced Non-small Cell Lung Cancer After Failure of at Least 1 Prior Platinum-based Treatment
    Medical condition: NSCLC
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2010-019423-61 Sponsor Protocol Number: GENRAS Start Date*: 2010-10-28
    Sponsor Name:Medizinische Universität Wien,Univ.Klinik f.Psychiatrie und Psychotherapie
    Full Title: GENRAS (GENetics of Response to Agomelatine vs. EScitalopram)
    Medical condition: depressive disorder
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2013-001656-35 Sponsor Protocol Number: 109MS408 Start Date*: 2014-04-07
    Sponsor Name:Biogen Idec Research Limited
    Full Title: A Multicenter, Open-Label Study Evaluating the Effectiveness of Oral Tecfidera™ (Dimethyl Fumarate) on MS Disease Activity and Patient-Reported Outcomes in Subjects with Relapsing-Remitting Multipl...
    Medical condition: Relapsing-Remitting Multiple Sclerosis
    Disease: Version SOC Term Classification Code Term Level
    19.0 10029205 - Nervous system disorders 10029205 Nervous system disorders SOC
    19.0 10029205 - Nervous system disorders 10063399 Relapsing-remitting multiple sclerosis PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed) HU (Completed) BE (Completed) PT (Completed) IT (Completed) CZ (Completed) SK (Completed) ES (Completed) SI (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2014-001463-12 Sponsor Protocol Number: P130936 Start Date*: 2015-03-13
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title:
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    17.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10033610 Pancreatic carcinoma metastatic PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-002408-34 Sponsor Protocol Number: Nosponsor Start Date*: 2011-10-05
    Sponsor Name:Matti Ristikankare
    Full Title:
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    14.0 10017947 - Gastrointestinal disorders 10000058 Abdominal crampy pains LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: View results
    EudraCT Number: 2014-003284-38 Sponsor Protocol Number: EVG001SAH Start Date*: 2016-02-15
    Sponsor Name:Evgen Pharma plc
    Full Title: SFX-01 AFTER SUBARACHNOID HAEMORRHAGE
    Medical condition: Subarachnoid Haemorrhage
    Disease: Version SOC Term Classification Code Term Level
    20.1 10022117 - Injury, poisoning and procedural complications 10042316 Subarachnoid haemorrhage PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2015-005774-37 Sponsor Protocol Number: GETNE-2016-01 Start Date*: 2016-04-29
    Sponsor Name:Grupo Español de Tumores Neuroendocrinos. SECRETARÍA TÉCNICA GETNE (GETNE)
    Full Title: Phase II study to evaluate efficacy of rechallenge with Sunitinib in Patients with Metastatic Pancreatic Neuroendocrine Tumor (pNETs) well differentiated G1/2 advanced or metastatic who previously ...
    Medical condition: Metastatic Pancreatic Neuroendocrine Tumor (pNETs) well differentiated G1/2 advanced or metastatic
    Disease: Version SOC Term Classification Code Term Level
    18.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10068909 Pancreatic neuroendocrine tumour metastatic PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2013-003378-28 Sponsor Protocol Number: 2013071339 Start Date*: 2014-04-09
    Sponsor Name:Department of Medicine, Køge University Hospital [...]
    1. Department of Medicine, Køge University Hospital
    2. Department of Medicine, Køge University Hospital
    Full Title: THE ROLE OF PHAGES IN MICROBIAL GUT ECOLOGY A STUDY OF INTERACTIONS BETWEEN ANTIBIOTICS AND THE GUT MICROBIOTA IN HEALTHY VOLUNTEERS A PARALLEL, SINGLE-BLIND, RANDOMIZED, CONTROLLED STUDY
    Medical condition: Resistance to anitbiotics
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004862 10004052 Bacterial resistance LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2013-000383-28 Sponsor Protocol Number: CLI/016P Start Date*: 2015-01-12
    Sponsor Name:Dexcel Pharma Technologies Ltd.
    Full Title: The Efficacy and Safety of Chlorhexidine Gluconate Chip (PerioChip®) in Therapy of Peri-implantitis
    Medical condition: Peri-implantitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-003539-56 Sponsor Protocol Number: 1.01 Start Date*: 2006-11-10
    Sponsor Name:Medical University of Vienna, Department of Internal Medicine IV
    Full Title: Simvastatin in patients with septic shock
    Medical condition: Septic shock
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2016-003852-60 Sponsor Protocol Number: NSR-RPGR-01 Start Date*: 2017-01-09
    Sponsor Name:NightstaRx Limited
    Full Title: A Dose Escalation (Phase 1), and Dose Expansion (Phase 2/3) Clinical Trial of Retinal Gene Therapy for X-linked Retinitis Pigmentosa Using an Adeno-Associated Viral Vector (AAV8) Encoding Retinitis...
    Medical condition: X-Linked retinitis pigmentosa (XLRP)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10010331 - Congenital, familial and genetic disorders 10038914 Retinitis pigmentosa PT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2010-019236-12 Sponsor Protocol Number: GEMCAD-1002 Start Date*: 2010-10-13
    Sponsor Name:Grupo Español Multidisciplinar en Cáncer Digestivo (GEMCAD)
    Full Title: Ensayo clínico fase II de un solo brazo, multicéntrico y prospectivo para la validación de biomarcadores en pacientes con cáncer colorrectal avanzado y/o metastásico con gen KRAS no mutado tratados...
    Medical condition: Cancer colorrectal avanzado y/o metastásico
    Disease: Version SOC Term Classification Code Term Level
    11 10061451 Cáncer colorrectal PT
    11 10052358 Cáncer metastásico colorrectal PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2012-004707-12 Sponsor Protocol Number: CRAD001C2X01B Start Date*: 2013-05-16
    Sponsor Name:Novartis Pharma Services AG
    Full Title: An open-label, multi-center everolimus roll-over protocol for patients who have completed a previous Novartis-sponsored everolimus study and are judged by the investigator to benefit from continued...
    Medical condition: Disease corresponding to the Novartis-sponsored study the patient will be transitioning from
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) NL (Prematurely Ended) IT (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2004-002834-20 Sponsor Protocol Number: HCC-Rap-001 Start Date*: 2008-01-23
    Sponsor Name:Universitätsklinik für Innere Medizin IV, Klinische Abteilung Gastroenterologie und Hepatologie
    Full Title: Behandlung des fortgeschrittenen hepatozellulären Karzinoms mit dem mTOR-Inhibitor Rapamycin (HCC-Rap-001) Treatment of advanced hepatocellular carcinoma with the mTOR-inhibitor rapamycin (HCC-Ra...
    Medical condition: Advanced hepatocellular carcinoma (HCC)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2005-005184-29 Sponsor Protocol Number: P305-R-EG04 Start Date*: 2006-02-21
    Sponsor Name:GABA GmbH
    Full Title: Prevention of incipient carious lesions (white spot lesions) in patients with fixed orthodontic appliances following the application of elmex® gelée
    Medical condition: incipient carious lesions (white spot lesions)
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2014-004509-34 Sponsor Protocol Number: CUDC-907-201 Start Date*: 2016-10-13
    Sponsor Name:Curis, Inc.
    Full Title: Open-Label, Phase 2 Study to Evaluate the Efficacy and Safety of CUDC-907 in Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma, Including Patients With MYC Alterations
    Medical condition: Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma including patients with MYC alterations
    Disease: Version SOC Term Classification Code Term Level
    21.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10012821 Diffuse large B-cell lymphoma recurrent PT
    21.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10012822 Diffuse large B-cell lymphoma refractory PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) NL (Completed) ES (Completed) HU (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2013-003352-20 Sponsor Protocol Number: 469055 Start Date*: 2016-07-18
    Sponsor Name:University Medical Center of Johannes -Gutenberg University Mainz
    Full Title: Correlation of functional and structural outcomes with serum antibody profiles in patients with neovascular age-related macular degeneration treated with ranibizumab and healthy subjects: a prospec...
    Medical condition: Neovascular age-related macular degeneration (AMD)
    Disease: Version SOC Term Classification Code Term Level
    19.0 10015919 - Eye disorders 10071129 Neovascular age-related macular degeneration PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2016-000833-40 Sponsor Protocol Number: CCR4502 Start Date*: 2016-10-07
    Sponsor Name:The Institute of Cancer Research
    Full Title: Phase I ’run in’ study followed by randomised phase II trial testing intra-tumoural hydrogen peroxide as a radiation sensitizer in patients with locally advanced/recurrent breast cancer in terms of...
    Medical condition: Women with locally advanced/recurrent breast cancer
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2018-003257-16 Sponsor Protocol Number: CitraFleet_H-2018 Start Date*: 2018-11-07
    Sponsor Name:Goodwill Pharma Kft.
    Full Title: Efficacy, Safety and Tolerability of CitraFleet, a New Bowel Cleansing Agent – a Prospective, Single-Center, Single-Group Phase IV Study
    Medical condition: Colonoscopy bowel preparation
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004848 10017963 Gastrointestinal and abdominal imaging procedures HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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