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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44352   clinical trials with a EudraCT protocol, of which   7379   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,352 result(s) found. Displaying page 1,357 of 2,218.
    «« First « Previous 1353  1354  1355  1356  1357  1358  1359  1360  1361  Next» Last»»
    EudraCT Number: 2004-004953-24 Sponsor Protocol Number: 20041202 Start Date*: 2005-07-20
    Sponsor Name:Department of Anesthesiology, University Hospital Erlangen
    Full Title: A double-blind placebo-controlled two period crossover study of pregabalin and aprepitant in the electrical hyperalgesia model of central sensitisation in healthy volunteers
    Medical condition: The primary aim of the present study is therefore to investigate the effects of oral pregabalin and aprepitant on experimentally-induced central sensitization in the electrical hyperalgesia model, ...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-000334-12 Sponsor Protocol Number: M/MTAST/01 Start Date*: 2006-03-20
    Sponsor Name:Almirall Prodesfarma
    Full Title: A RANDOMIZED, PLACEBO CONTROLLED, DOUBLE-BLIND, CROSS-OVER, MONOCENTER STUDY TO EVALUATE THE EFFECT OF A 7-DAY MONTELUKAST TREATMENT ON AIRWAY INFLAMMATION AND FUNCTION BY MEANS OF BRONCHOPROVOCATI...
    Medical condition: Mild to moderate asthma according to GINA (Global initiative for Asthma, 2004) guidelines.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-002369-35 Sponsor Protocol Number: Bromelain-Häma-2P Start Date*: 2006-06-14
    Sponsor Name:Ursapharm Arzneimittel GmbH&Co. KG
    Full Title: Reduction of pain under pressure of an experimentally induced hematoma in healthy volunteers by two Bromelain preparations (Bromelain-POS(R) and Traumanase(R) forte).
    Medical condition: healthy subjects
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2004-005211-28 Sponsor Protocol Number: 20041221 Start Date*: 2005-07-20
    Sponsor Name:Department of Anesthesiology, University Hospital of Erlangen
    Full Title: A double-blind placebo-controlled four period crossover study of paracetamol and tramadol in the electrical hyperalgesia model of central sensitisation in healthy volunteers
    Medical condition: The primary aim of the present study is to investigate the effects of intravenous paracetamol and tramadol and their combination on the experimentally-induced central sensitization in an electrical...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-000709-70 Sponsor Protocol Number: Y-47-52120-051 Start Date*: 2005-12-21
    Sponsor Name:Ipsen Ltd
    Full Title: A Phase III Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of Dysport® for the Treatment of Cervical Dystonia
    Medical condition: Cervical Dystonia (CD)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-004337-18 Sponsor Protocol Number: PSN357AB-CS02 Start Date*: 2005-12-07
    Sponsor Name:OSI-prosidion Ltd.
    Full Title: A randomised, double-blind, placebo-controlled, multiple dose, time-lagged cohort, dose-escalation trial, investigating the pharmacodynamics, safety and tolerability, and the pharmacokinetics of PS...
    Medical condition: Diabetes type-II
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-001503-26 Sponsor Protocol Number: FER-CARS-03 Start Date*: 2008-10-17
    Sponsor Name:Vifor Pharma - Vifor (International) AG
    Full Title: EFfect of Ferric Carboxymaltose on exercIse CApacity and Cardiac function in patients with iron deficiencY and chronic Heart Failure (EFFICACY-HF)
    Medical condition: Ambulatory patients with stable symptomatic chronic CHF (congestive heart failure) and iron deficiency.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10008908 Chronic heart failure LLT
    9.1 10002062 Anaemia iron deficiency LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended) DE (Completed) NL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-004279-20 Sponsor Protocol Number: TUD-OCT-AD-025 Start Date*: 2007-11-14
    Sponsor Name:Technical University Dresden
    Full Title: Comparison of the atrophogenic effect of hydrocortisone 1% cream and Elidel (Pimecrolimus 1% cream) assessed by Optical Coherence Tomography (OCT) and 20-MHZ ultrasound of uninvolved skin in patien...
    Medical condition: patients with mild to moderate atopic dermatitis not affecting the test areas
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-000968-25 Sponsor Protocol Number: CHL1/02-2006/M; INN60M2006 Start Date*: 2007-07-16
    Sponsor Name:SINTETICA ITALIA S.R.L.
    Full Title: Prospective, blind observer, randomised clinical study to investigate and compare the efficacy of intrathecal plain solutions containing Chloroprocaine 1% (50 mg) versus Bupivacaine 0.5% (10 mg)
    Medical condition: patients undergoing elective short-duration (< 40 min) in low abdominal (gynaecology and urology disciplines) or lower limbs (no more than 1/3 of cases) surgery under spinal anaesthesia.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10041536 Spinal anaesthesia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-002213-13 Sponsor Protocol Number: 6 BT Start Date*: 2006-09-28
    Sponsor Name:Menarini Ricerche S.p.A.
    Full Title: A Phase I/II, Randomised, Double-blind, Placebo-controlled, Parallel Group Study to Evaluate the Efficacy, Systemic Absorption and Dihydropyrimidine Dehydrogenase (DPD) Enzyme Activity Following Re...
    Medical condition: Herpes Simplex Labialis (HSL)
    Disease: Version SOC Term Classification Code Term Level
    8.1 10019942 Herpes labialis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-003599-39 Sponsor Protocol Number: AMD3100-3102-DE Start Date*: 2005-12-02
    Sponsor Name:AnorMED Corp.
    Full Title: A randomized, double-blind, placebo-controlled, comparative trial of AMD3100 (240 mcg/kg) plus G-CSF (10 mcg/kg) versus G-CSF (10 mcg/kg) plus placebo to mobilize and collect greater than or equal ...
    Medical condition: Mobilization of stem cells prior to autologous stem cell transplantation in patients with multiple myeloma
    Disease: Version SOC Term Classification Code Term Level
    8.1 10028228 Multiple myeloma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-000694-22 Sponsor Protocol Number: ACA-Germ-04-5 Start Date*: 2005-11-17
    Sponsor Name:Prof. Dr.Christian Werner
    Full Title: „Levobupivacaine for postoperative pain control in patients with knee arthroplasty – a comparison with ropivacaine“
    Medical condition: patients undergoing total knee arthroplasty
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-007456-96 Sponsor Protocol Number: GS-US-227-0106 Start Date*: 2009-07-29
    Sponsor Name:Gilead Sciences, Inc
    Full Title: A Phase 2b, Double blind, Randomized, Parallel Group, Placebo Controlled Study to Evaluate the Safety, Tolerability, and Efficacy of GS 9450 in Adults with Chronic Hepatitis C Virus Infection
    Medical condition: Chronic Hepatitis C Virus Infection
    Disease: Version SOC Term Classification Code Term Level
    9.1 10008912 Chronic hepatitis C LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed) GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-014857-34 Sponsor Protocol Number: FAU-001 Start Date*: 2010-02-01
    Sponsor Name:Universitätsklinikum Erlangen
    Full Title: Intra-individual, randomized multicentric comparison of the MRI contrast agents Gadovist 1.0 versus Dotarem in patients with Multiple Sclerosis at 3T
    Medical condition: Patients with clinically definite MS or a clinically isolated episode of CNS involvement and disease dissemination in space, according to the McDonald’s criteria
    Disease: Version SOC Term Classification Code Term Level
    12.0 10028245 Multiple sclerosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2010-022713-26 Sponsor Protocol Number: CAMN107DDE12 Start Date*: 2011-03-30
    Sponsor Name:Novartis Pharma GmbH
    Full Title: Localized gastrointestinal stromal tumors (GIST): an exploratory open-label, multicenter, single-arm phase II study to evaluate the efficacy of 2 years of adjuvant nilotinib treatment following at ...
    Medical condition: localized gastrointestinal stromal tumors (GIST)
    Disease: Version SOC Term Classification Code Term Level
    13.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10062427 Gastrointestinal stromal tumor LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-017085-22 Sponsor Protocol Number: SIMAR Start Date*: 2010-04-27
    Sponsor Name:Technische Universität München
    Full Title: Sugammadex improves muscle function after standard neuromuscular recovery (SIMAR) [Verbesserung der Muskelfunktion durch Sugammadex nach normaler neuromuskulärer Erholung]
    Medical condition: This study wants to test if sugammadex is able to improve postoperative muscle weakness/function and subjective well-being even after complete spontaneous recovery to TOF 0.9 of a rocuronium-induce...
    Disease: Version SOC Term Classification Code Term Level
    12.0 10029315 Neuromuscular blockade PT
    12.0 10057286 Neuromuscular blockade reversal PT
    12.1 10036278 Postoperative complications NOS LLT
    12.1 10052617 Postoperative care LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2010-018739-17 Sponsor Protocol Number: OSI-906-206 Start Date*: 2010-10-08
    Sponsor Name:Astellas Pharma Global Development, Inc.
    Full Title: A Randomized, Placebo-controlled, Double-blind Phase 2 Study of Second-line Treatment with OSI-906 in Patients with Advanced Hepatocellular Carcinoma (HCC) after Failure of First-line Treatment wit...
    Medical condition: Hepatocellular Carcinoma
    Disease: Version SOC Term Classification Code Term Level
    13.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10019829 Hepatocellular carcinoma recurrent LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Prematurely Ended) ES (Prematurely Ended) DE (Completed) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-017676-24 Sponsor Protocol Number: CSPP100ADE07T Start Date*: 2010-02-26
    Sponsor Name:University Hospital Erlangen
    Full Title: Randomized, double blind, active-controlled, parallel study to analyse effects of the combination of aliskiren and valsartan on the vascular structure and function of retinal vessels
    Medical condition: Hypertension
    Disease: Version SOC Term Classification Code Term Level
    12.1 10020772 Hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-001560-37 Sponsor Protocol Number: GEM-658-EBE-0024-I Start Date*: Information not available in EudraCT
    Sponsor Name:Medizinische Fakultät der TU-München, vertreten durch den Dekan
    Full Title: Sequentielle Kombination einer Chemotherapie mit Gemcitabine/Oxaliplatin und photodynamischen Therapie beim fortgeschrittenen Gallengangskarzinom
    Medical condition: - advanced cholangiocarcinoma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10008594 Cholangiocarcinoma non-resectable LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-013499-29 Sponsor Protocol Number: SUNDRO20 Start Date*: Information not available in EudraCT
    Sponsor Name:Technische Universität München
    Full Title: Dosisfindungsstudie für Sugammadex und Neostigmin zur Reversierung einer geringen neuromuskulären Restblockade (train of four ratio 0,2) [Sugammadex and Neostigmine dose finding study for reversal ...
    Medical condition: Dose finding study for sugammadex and/or neostigmine at residual neuromuscular blockade (whereas residual neuromuscular blockade is defined as a TOF of 0.2 in this study).
    Disease: Version SOC Term Classification Code Term Level
    9.1 10057286 Neuromuscular blockade reversal LLT
    9.1 10057286 Neuromuscular blockade reversal PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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