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Clinical trials for colon cancer

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    The EU Clinical Trials Register currently displays   44349   clinical trials with a EudraCT protocol, of which   7376   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    765 result(s) found for: colon cancer. Displaying page 16 of 39.
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    EudraCT Number: 2006-002887-25 Sponsor Protocol Number: 2601 Start Date*: 2006-06-27
    Sponsor Name:GOIM GRUPPO ONCOLOGICO MERIDIONALE
    Full Title: Bevacizumab+folfiri in untreated patients with advanced colorectal cancer. A phase II multicenter study of the Gruppo Oncologico dell'Italia Meridionale. (GOIM).
    Medical condition: untreated patients with advanced colorectal cancer.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10010035 Colorectal cancer stage IV LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-004285-35 Sponsor Protocol Number: CA224-123 Start Date*: 2022-07-12
    Sponsor Name:Bristol-Myers Squibb International Corporation
    Full Title: A Phase 3, Randomized, Open-label (Sponsor Blinded) Study of Relatlimab-nivolumab Fixed-dose Combination Versus Regorafenib or Trifluridine + Tipiracil (TAS-102) for Participants with Later-lines o...
    Medical condition: Metastatic Colorectal Cancer
    Disease: Version SOC Term Classification Code Term Level
    21.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10052362 Metastatic colorectal cancer LLT
    21.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10052358 Colorectal cancer metastatic PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned) AT (Trial now transitioned) ES (Ongoing) DE (Trial now transitioned) IT (Trial now transitioned) PL (Trial now transitioned) NL (Trial now transitioned) CZ (Trial now transitioned) BE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2012-003342-33 Sponsor Protocol Number: STH16359 Start Date*: 2012-09-28
    Sponsor Name:Sheffield Teaching Hospitals NHS Foundation Trust
    Full Title: Optimising the use of Entonox during screening colonoscopy: an open randomised controlled trial
    Medical condition: Colonoscopy
    Disease: Version SOC Term Classification Code Term Level
    14.1 10022891 - Investigations 10010007 Colonoscopy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-000331-14 Sponsor Protocol Number: ICORG 05-02/NSABP C-08 Start Date*: 2005-04-08
    Sponsor Name:All Ireland Cooperative Oncology Research Group
    Full Title: A phase III clinical trial comparing infusional 5-Fluorouracil (5-FU), Leucovorin and Oxaliplatin (mFOLFOX -6) every 2 weeks with Bevacizumab to the same regimen without Bevacizumab for the treatme...
    Medical condition: Resected stage II or stage III adenocarcinoma of the colon
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Completed)
    Trial results: View results
    EudraCT Number: 2015-001105-13 Sponsor Protocol Number: STREAM Start Date*: 2015-06-19
    Sponsor Name:ISTITUTO NAZIONALE TUMORI - IRCCS FONDAZIONE PASCALE
    Full Title: Regorafenib monotherapy as second-line treatment of patients with RAS-mutant advanced colorectal cancer: a multicentre, single-arm, two-stage, phase 2 study.
    Medical condition: patients with RAS-mutant advanced colorectal cancer
    Disease: Version SOC Term Classification Code Term Level
    21.0 100000004864 10038029 Rectal adenocarcinoma stage IV LLT
    21.0 100000004864 10001172 Adenocarcinoma of colon stage IV LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-003737-25 Sponsor Protocol Number: STX0206-SIRFLOXstudy Start Date*: 2008-11-26
    Sponsor Name:Sirtex Technology Pty Ltd
    Full Title: Randomised comparative study of folfox6m plus SIR-Spheres microspheres versus folfox6m alone as first line treatment in patients with non-resectable liver metastases from primary colorectal carcinoma
    Medical condition: Non-resectable liver metastasis from primary colorectal carcinoma
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004864 10052362 Metastatic colorectal cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) ES (Completed) IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-013756-79 Sponsor Protocol Number: VECTOX Start Date*: 2010-09-28
    Sponsor Name:Anticancer Informing "Me Gnosi Nika"
    Full Title: VECTIBIX PLUS OXALIPLATIN-BASED ADJUVANT TREATMENT OF RECTAL CANCER
    Medical condition: Rectal cancer stage 2-3 includes neoadjuvant chemo radiation, followed by resection, followed by adjuvant chemotherapy.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10010033 Colorectal cancer stage II LLT
    12.1 10010034 Colorectal cancer stage III LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2010-019236-12 Sponsor Protocol Number: GEMCAD-1002 Start Date*: 2010-10-13
    Sponsor Name:Grupo Español Multidisciplinar en Cáncer Digestivo (GEMCAD)
    Full Title: Ensayo clínico fase II de un solo brazo, multicéntrico y prospectivo para la validación de biomarcadores en pacientes con cáncer colorrectal avanzado y/o metastásico con gen KRAS no mutado tratados...
    Medical condition: Cancer colorrectal avanzado y/o metastásico
    Disease: Version SOC Term Classification Code Term Level
    11 10061451 Cáncer colorrectal PT
    11 10052358 Cáncer metastásico colorrectal PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2009-017432-40 Sponsor Protocol Number: MGN1703-C02 Start Date*: 2010-04-13
    Sponsor Name:MOLOGEN AG
    Full Title: A Phase 2, Randomized, Double-blind, Placebo-controlled, Multi-Center Clinical Study to Evaluate Efficacy and Safety of a Maintenance Therapy with Immunomodulator MGN1703 in Patients with Advanced ...
    Medical condition: Patients with advanced colorectal carcinoma (AJCC Stage IV) with disease control after initial first-line therapy
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004864 10010036 Colorectal carcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Prematurely Ended) GB (Completed) CZ (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-005422-30 Sponsor Protocol Number: AIO-KRK-0212 Start Date*: 2014-01-09
    Sponsor Name:AIO Studien gGmbH
    Full Title: Randomized Phase II study for evaluation of efficacy and safety of maintenance treatment with 5-FU/FA plus panitumumab vs. 5-FU/FA alone after prior induction treatment with mFOLFOX6 plus panitumum...
    Medical condition: Metastatic colorectal cancer
    Disease: Version SOC Term Classification Code Term Level
    21.0 100000004864 10052362 Metastatic colorectal cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-005215-29 Sponsor Protocol Number: 03-CoFactor Start Date*: 2005-06-03
    Sponsor Name:ADVENTRX Pharmaceuticals Inc
    Full Title: A Multi-Center, Open Label, Parallel Group, Randomised, Phase IIB Clinical Trial to Evaluate the Safety and Efficacy of CoFactor and 5-FU versus Leucovorin and 5-FU in Subjects with Metastatic Colo...
    Medical condition: Metastatic Colorectal Carcinoma
    Disease: Version SOC Term Classification Code Term Level
    7.1 10052358 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-000394-39 Sponsor Protocol Number: KFEAC14.01 Start Date*: 2014-05-05
    Sponsor Name:Odense University Hospital
    Full Title: Full dose S-1 monotherapy compared to reduced dose S-1/oxaliplatin combination therapy as first-line treatment for older patients with metastatic colorectal cancer
    Medical condition: Treatment of older (≥ 70 years) patients with metastatic colorectal cancer
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10052358 Colorectal cancer metastatic PT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: DK (Completed) NO (Completed) FI (Completed)
    Trial results: View results
    EudraCT Number: 2018-002250-79 Sponsor Protocol Number: CCR4938 Start Date*: 2018-11-29
    Sponsor Name:The Royal Marsden NHS Foundation Trust
    Full Title: iSCORE: Immunotherapy Sequencing in COlon and REctal Cancer.
    Medical condition: Metastatic RAS wild-type colorectal cancer which has previously responded to FOLFIRI chemotherapy and Cetuximab treatment but then progressed
    Disease:
    Population Age: Gender:
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2015-000894-11 Sponsor Protocol Number: IRST153.04 Start Date*: 2016-04-13
    Sponsor Name:ISTITUTO SCIENTIFICO ROMAGNOLO PER LO STUDIO E LA CURA DEI TUMORI (IRST) S.R.L. IRCCS
    Full Title: Vaccination with autologous dendritic cells loaded with autologous tumour homogenate after curative resection for stage IV colorectal cancer: a phase II study
    Medical condition: colorectal cancer
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004864 10038029 Rectal adenocarcinoma stage IV LLT
    20.0 100000004864 10001172 Adenocarcinoma of colon stage IV LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2017-001194-16 Sponsor Protocol Number: DDD17CRCP2 Start Date*: 2017-12-11
    Sponsor Name:KU Leuven
    Full Title: Pharmacokinetics of celecoxib for the prevention/treatment of colorectal cancer: optimization of intestinal sampling for celecoxib in healthy volunteers
    Medical condition: Colorectal cancer
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2005-005154-44 Sponsor Protocol Number: OPERA Start Date*: 2006-03-02
    Sponsor Name:Universitätsklinikum Hamburg-Eppendorf
    Full Title: OPERA: OXALIPLATIN AND CETUXIMAB IN FIRST-LINE TREATMENT OF mCRC Open, non-controlled, multicenter phase II study evaluating 5-FU/FA plus oxaliplatin (FOLFOX-4) plus cetuximab as first-line treatme...
    Medical condition: metastasized colorectal cancer
    Disease: Version SOC Term Classification Code Term Level
    8.1 10052358 Colorectal cancer metastatic LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2021-006700-32 Sponsor Protocol Number: 80013 Start Date*: 2022-07-13
    Sponsor Name:Meander Medical Centre
    Full Title: A pilot study to assess the safety and feasibility of fluorescent sentinel lymph node identification in colon carcinoma using submucosal bevacizumab-800CW.
    Medical condition: Colon carcinoma
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-006796-41 Sponsor Protocol Number: 80117 Start Date*: 2022-07-13
    Sponsor Name:Meander Medical Centre
    Full Title: A pilot study to assess the safety and feasibility of fluorescent sentinel lymph node identification in colon carcinoma using intravenous bevacizumab-800CW
    Medical condition: Colon carcinoma
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-000834-50 Sponsor Protocol Number: MGN1703-C06 Start Date*: 2014-07-09
    Sponsor Name:MOLOGEN AG
    Full Title: IMPALA-Trial: Evaluation of an immunomodulatory maintenance treatment in patients with metastatic colorectal cancer with tumor reduction during induction treatment - A phase III trial
    Medical condition: Metastatic colorectal cancer
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004864 10010036 Colorectal carcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended) DE (Completed) BE (Prematurely Ended) IT (Ongoing) EE (Prematurely Ended) AT (Prematurely Ended) ES (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-004866-42 Sponsor Protocol Number: AIO KRK 0107 Start Date*: 2009-07-27
    Sponsor Name:AIO-Studien-gGmbH
    Full Title: An Open-label Randomized Phase II Study of Panitumumab Plus Oral Capecitabine and Infusional Oxaliplatin (XELOX) or XELOX alone for Second-line Treatment of Patients with Metastatic Clororectal Can...
    Medical condition: Metastatic colorectal cancer (mCRC)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10052362 Metastatic colorectal cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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