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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44380   clinical trials with a EudraCT protocol, of which   7392   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,380 result(s) found. Displaying page 168 of 2,219.
    EudraCT Number: 2004-000784-97 Sponsor Protocol Number: SB-275833/032 Start Date*: 2004-02-16
    Sponsor Name:GlaxoSmithKline Research & Development Ltd
    Full Title: A Randomized, Double-blind, Double-Dummy, Multicenter, Non-inferiority Phase III Study to Assess the Safety and Efficacy of Topical 1% SB-275833 Ointment, Applied Twice Daily, versus Oral Cephalexi...
    Medical condition: Secondarily-Infected Dermatoses
    Disease: Version SOC Term Classification Code Term Level
    7.0 10012470 PT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2004-000798-71 Sponsor Protocol Number: 1 Start Date*: 2004-08-11
    Sponsor Name:Imperial College London
    Full Title: Efficacy of Levetiracetam in Pendular Nystagmus: A Randomized, Double-blind, Placebo-controlled trial with crossover
    Medical condition: Pendular Nystagmus from various etiology
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2004-000799-15 Sponsor Protocol Number: 04-04074 Start Date*: 2004-09-09
    Sponsor Name:Aker University Hospital
    Full Title: DOES BENFOTIAMINE SUPPLEMENTATION REDUCE SERUM LEVELS OF ADVANCED GLYCATION END PRODUCTS AND BIOCHEMICAL MARKERS OF VASCULAR DYSFUNCTION IN TYPE 1 DIABETES?
    Medical condition: Type 1 diabetes
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NO (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-000803-17 Sponsor Protocol Number: SAVE Start Date*: 2006-01-06
    Sponsor Name:The SAVE trial group
    Full Title: Prospective, controlled clinical study on the effect of 120 mg depot-methyl-prednisolone compared to placebo on the course of recent onset arthritis
    Medical condition: Early undifferentiated arthritis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-000816-24 Sponsor Protocol Number: FRAN-03-001 Start Date*: 2004-10-28
    Sponsor Name:Abbott France
    Full Title: A Pilot, Open-Label, Randomized, Comparative Study of the Antiviral Efficacy of Lopinavir/Ritonavir Single-Drug Regimen versus Lopinavir/Ritonavir in Combination with Lamivudine/Zidovudine in Antir...
    Medical condition: HIV-1 Infection
    Disease: Version SOC Term Classification Code Term Level
    7.0 10020192 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2004-000914-37 Sponsor Protocol Number: NEU 1X Start Date*: 2004-08-12
    Sponsor Name:Neurim Pharmaceuticals (1991) Ltd
    Full Title: A DOUBLE-BLIND, PARALLEL GROUP, RANDOMISED, PLACEBO CONTROLLED STUDY OF THE EFFICACY AND SAFETY OF CIRCADIN® 2MG IN THE IMPROVEMENT OF SLEEP QUALITY IN PATIENTS WITH INSOMNIA AGED 55-80 YEARS.
    Medical condition: Primary Insomnia in adults over 55 years
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2004-000915-25 Sponsor Protocol Number: D1447C00144 Start Date*: 2005-04-22
    Sponsor Name:AstraZeneca R&D Sodertalje
    Full Title: Multicenter, Randomized, Parallel-group, Double-blind, Placebo-controlled Phase III Study of the Efficacy and Safety of Quetiapine Fumarate and Lithium as Monotherapy for up to 104 weeks Maintenanc...
    Medical condition: Bipolar I Disorder
    Disease: Version SOC Term Classification Code Term Level
    9.1 10004939 Bipolar I disorder LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2004-000929-30 Sponsor Protocol Number: MHE100185 Start Date*: 2004-07-08
    Sponsor Name:GLAXO SMITHKLINE
    Full Title: A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel Group Phase III Study to Evaluate Corticosteroid-reduction and -sparing Effects of Mepolizumab 750 mg Intravenous in Subjects w...
    Medical condition: HES
    Disease: Version SOC Term Classification Code Term Level
    6.1 10048643 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2004-000940-26 Sponsor Protocol Number: CASM981C2314 Start Date*: 2004-09-24
    Sponsor Name:Novartis Pharma
    Full Title: A 22-week randomized, multicenter, parallel-group, double-blind study to compare a pimecrolimus 1 % (Elidel) twice daily (b.i.d.) maintenance dosing regimen to a once daily (o.d.) maintenance dosin...
    Medical condition: Atopic dermatitis
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: FI (Completed) AT (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2004-000663-99 Sponsor Protocol Number: C-1900 Start Date*: 2004-09-10
    Sponsor Name:Biogen Idec Inc. [...]
    1. Biogen Idec Inc.
    2. Biogen Idec Ltd
    Full Title: Double-Blind, Placebo-Controlled, Dose-Ranging Study to Determine the Efficacy and Safety of BG00012 in Subjects with Relapsing-Remitting Multiple Sclerosis.
    Medical condition: MS is a chronic disease of the CNS. It's a disease of young adults, primarily women, with disease onset typically occuring between the ages of 20 and 40. Although etiology is uncertain, evidence p...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed) HU (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2004-002821-30 Sponsor Protocol Number: 12 Start Date*: 2004-12-09
    Sponsor Name:Institute of Oncology, Vilnius University
    Full Title: Study of the efficacy of intravesical instillations of interleukin-2 in treatment of superficial bladder cancer
    Medical condition: Ta,T1 /G1,G2,G3 superficial bladder cancer
    Disease: Version SOC Term Classification Code Term Level
    9.1 10005003 Bladder cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2004-002831-14 Sponsor Protocol Number: CZOL446GDE13 Start Date*: 2005-06-09
    Sponsor Name:Novartis Pharma GmbH
    Full Title: Influence of Zoledronic acid (Zometa®) on bone mineral density and bone ultrasonometry in premenopausal women with hormone receptor negative breast cancer and adjuvant chemotherapeutic treatment
    Medical condition: Primary, hormonreceptor negative breast cancer in premenopausal women
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2004-002836-25 Sponsor Protocol Number: QGUY/2004/IL 4-13/01 Start Date*: 2004-12-15
    Sponsor Name:Aerovance Inc.
    Full Title: A Phase IIa Study To Investigate The Effects of AER 001on Antigen Challenge In Atopic Asthmatic Subjects Following Repeated Administration.
    Medical condition: Asthma is characterised by an infiltration of the bronchial mucosa with activated T-lymphocytes (T-cells), eosinophils, and to a lessor extent polymorphonuclear leukocytes.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-002842-37 Sponsor Protocol Number: FG-56-02 Start Date*: 2004-11-23
    Sponsor Name:Fujisawa GmbH
    Full Title: A randomised, double-blind, vehicle-controlled, parallel group, multicentre, proof of concept, phase II clinical study to investigate the efficacy and safety of 1 % FR260500 gel in patients with fa...
    Medical condition: Mild to moderate facial acne vulgaris.
    Disease: Version SOC Term Classification Code Term Level
    7.0 10000519 LLT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: DE (Completed) GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2004-002113-36 Sponsor Protocol Number: EORTC 62012 Start Date*: 2003-05-20
    Sponsor Name:European Organisation for the Research and Treatment of Cancer
    Full Title: Randomised trial of single agent doxorubicin versus doxorubicin plus ifosfamide in the first line treatment of advanced or metastatic soft tissue sarcoma
    Medical condition: Locally advanced or metastatic soft tissue sarcoma
    Disease: Version SOC Term Classification Code Term Level
    8.1 10041299 HLGT
    Population Age: Adults Gender: Male, Female
    Trial protocol: SK (Completed)
    Trial results: View results
    EudraCT Number: 2004-004443-22 Sponsor Protocol Number: Spirig I 04-05 Start Date*: Information not available in EudraCT
    Sponsor Name:Spirig Pharma AG
    Full Title: Untersuchung der Wirksamkeit einer glycerinhaltigen Creme bei der Behandlung von Atopischer Dermatitis. Kontrolliert, randomisierte Doppel-Blind-Studie.
    Medical condition: Atopic Dermatitis
    Disease: Version SOC Term Classification Code Term Level
    7.0 10012438
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-002171-16 Sponsor Protocol Number: BAY 59-7939 / 11528 Start Date*: 2005-01-10
    Sponsor Name:Bayer HealthCare AG
    Full Title: Once-daily oral Direct Factor Xa Inhibitor BAY 59-7939 in Patients with acute symptomatic Deep Vein Thrombosis. The Einstein-DVT dose-finding study.
    Medical condition: Acute syntomatic deep vein thrombosis
    Disease: Version SOC Term Classification Code Term Level
    7.0 10051055
    Population Age: Gender: Male, Female
    Trial protocol: SE (Completed) DK (Completed) CZ (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2004-002184-24 Sponsor Protocol Number: PLAN-EC-HIPERL-02 Start Date*: 2005-03-01
    Sponsor Name:MADAUS, S.A.
    Full Title: Ensayo clínico multicéntrico, comparativo, doble ciego, paralelo de dos vías, de los efectos del tratamiento con cutículas de semillas de Plantago Ovata sobre el perfil lipídico de pacientes afecto...
    Medical condition: Pacientes diagnosticados de hipercolesterolemia, con un colesterol LDL superior o igual a 130 mg/dl e inferior o igual a 189 mg/dl. Con dos factores de riesgo cardiovascular.
    Disease: Version SOC Term Classification Code Term Level
    7.1 10020661 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-000405-56 Sponsor Protocol Number: GEICAM/2004-06 Start Date*: 2005-06-01
    Sponsor Name:GRUPO ESPAÑOL DE INVETIGACION EN CANCER DE MAMA (GEICAM)
    Full Title: RANDOMIZED CLINICAL TRIAL TO COMPARE THE BENEFIT OF ADDING HERCEPTIN TO CAPECITABINE PLUS VINORELBINE AS SECOND LINE TREATMENT FOR PATIENTS WITH LOCALLY ADVANCED NON OPERABLE OR METASTATIC BREAST ...
    Medical condition: PATIENTS WITH ADVANCED OR METASTATIC BREAST CANCER AND OVEREXPRESSION OF HER2.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-000408-16 Sponsor Protocol Number: HS-PM-013 Start Date*: 2005-04-05
    Sponsor Name:Karolinska University Hospital, Huddinge
    Full Title: Caffeine-mediated modulation of human experimental pain models
    Medical condition: Healthy human volunteer subjects
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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