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Clinical trials for PL 1

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44380   clinical trials with a EudraCT protocol, of which   7392   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    8,462 result(s) found for: PL 1. Displaying page 194 of 424.
    «« First « Previous 190  191  192  193  194  195  196  197  198  Next» Last»»
    EudraCT Number: 2012-002792-34 Sponsor Protocol Number: Bronch Start Date*: 2014-02-26
    Sponsor Name:University Hospitals Leicester NHS Trust
    Full Title: Phenotyping bronchiectasis based on aetiology, exacerbation characteristics and response to erythromycin.
    Medical condition: Bronchiectasis
    Disease: Version SOC Term Classification Code Term Level
    16.1 10038738 - Respiratory, thoracic and mediastinal disorders 10006445 Bronchiectasis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2013-003532-68 Sponsor Protocol Number: FIBCON Start Date*: 2014-03-11
    Sponsor Name:Guy's and St Thomas NHS Foundation Trust
    Full Title: Fibrinogen concentrate supplementation in the management of bleeding during paediatric cardiopulmonary bypass: a phase 1B/2A, open label dose escalation study (Version 1.0, Jan 28, 2014)
    Medical condition: Neonates and infants who are at risk of mediastinal bleeding following cardiopulmonary bypass surgery for congenital heart disease
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004849 10055817 Haemorrhage intrapericardial LLT
    16.1 100000004850 10010495 Congenital heart disease NOS LLT
    Population Age: Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2019-003962-41 Sponsor Protocol Number: 17/0909 Start Date*: 2020-03-23
    Sponsor Name:University College London
    Full Title: Trial of Ondansetron as a Parkinson’s HAllucinations Treatment
    Medical condition: Adults aged over 18 years with Parkinson's disease and visual hallucinations
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004873 10047570 Visual hallucinations LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2018-004641-16 Sponsor Protocol Number: RG_18-272 Start Date*: 2020-02-14
    Sponsor Name:University of Birmingham
    Full Title: Letrozole or Clomifene, with or without metformin, for ovulation induction in women with polycystic ovary syndrome: a 2x2 factorial design randomised trial (The LOCI trial)
    Medical condition: Ovulation induction for women suffering from polycystic ovary syndrome
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004860 10002658 Anovulation LLT
    20.0 100000004872 10021935 Infertility, female, associated with anovulation LLT
    21.1 100000004872 10036050 Polycystic ovary LLT
    20.0 10036585 - Pregnancy, puerperium and perinatal conditions 10049550 Live birth PT
    20.0 10036585 - Pregnancy, puerperium and perinatal conditions 10049550 Live birth PT
    Population Age: Under 18, Adults Gender: Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2006-002337-20 Sponsor Protocol Number: 2412325-2 Start Date*: 2006-09-06
    Sponsor Name:Erasmus Medical Centre Rotterdam
    Full Title: Efficacy of peripherally targeted inhaled rhDNase for persistent obstructive asthma in childhood
    Medical condition: Asthma is a chronic inflammatory disorder in which many cells play a role, in particular mast cells, eosinophils and T lymphocytes. In susceptible individuals this inflammation causes recurrent epi...
    Disease: Version SOC Term Classification Code Term Level
    8.1 10003553 Asthma LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-004637-17 Sponsor Protocol Number: 191622-080-00 Start Date*: 2006-04-04
    Sponsor Name:ALLERGAN LTD
    Full Title: A Multicenter Study Evaluating the Efficacy and Safety of BOTOX® (Botulinum Toxin Type A) Purified Neurotoxin Complex as Headache Prophylaxis in Migraine Patients with 15 or More Headache Days per ...
    Medical condition: Headache prophylaxis in migraine patients with 15 or more headache days per month
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-003801-21 Sponsor Protocol Number: VPI-102-04 Start Date*: 2006-11-14
    Sponsor Name:Verus Pharmaceuticals Inc
    Full Title: A Randomised, Open-Label, Active-Controlled, Two-Period Crossover Study to Evaluate Relative Efficacy and Safety of Investigational Captisol-Enabled® Budesonide Inhalation Solution (CBIS) Delivered...
    Medical condition: Asthma
    Disease: Version SOC Term Classification Code Term Level
    8.1 10003553 Asthma LLT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-024045-69 Sponsor Protocol Number: TH1017 Start Date*: 2011-01-11
    Sponsor Name:Reckitt Benckiser Healthcare
    Full Title: A multi centre, randomised, double blind, single dose parallel group, placebo controlled study to investigate the efficacy of Strepsils Plus and Strepsils Extra in the treatment of sore throat due ...
    Medical condition: Sore throat due to upper respiratory tract infection
    Disease: Version SOC Term Classification Code Term Level
    12.1 10041367 sore throat LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2013-002419-87 Sponsor Protocol Number: 008722 Start Date*: 2014-03-18
    Sponsor Name:Queen Mary University London
    Full Title: Oxcarbazepine as a neuroprotective agent in MS: phase 2a trial
    Medical condition: Multiple sclerosis
    Disease: Version SOC Term Classification Code Term Level
    19.0 10029205 - Nervous system disorders 10028245 Multiple sclerosis PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-022496-66 Sponsor Protocol Number: UCL/09/0398 Start Date*: 2011-02-21
    Sponsor Name:Joint UCLH and UCL Biomedical Research Unit
    Full Title: An Evaluation of the Tolerability and Feasibility of combining 5-Amino-Levulinic Acid (5-ALA) with Carmustine Wafers (Gliadel) in the Surgical Management of Primary Glioblastoma (GALA-5 Trial)
    Medical condition: Primary glioblastoma
    Disease: Version SOC Term Classification Code Term Level
    14.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10018336 Glioblastoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2013-002951-14 Sponsor Protocol Number: 12/0357 Start Date*: 2016-06-17
    Sponsor Name:University College London
    Full Title: Human papillomavirus infection: a randomised controlled trial of Imiquimod cream (5%) versus Podophyllotoxin cream (0.15%), in combination with quadrivalent human papillomavirus or control vaccinat...
    Medical condition: Anogenital warts
    Disease: Version SOC Term Classification Code Term Level
    20.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10059313 Anogenital warts PT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10018182 Genital warts LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2014-004634-26 Sponsor Protocol Number: 4896 Start Date*: 2015-05-20
    Sponsor Name:Royal Liverpool University Hospital [...]
    1. Royal Liverpool University Hospital
    2. Liverpool School of Tropical Medicine
    Full Title: The Effect of Live Attenuated Influenza Vaccine (LAIV) on Experimental Human Pneumococcal Colonisation (EHPC) Study
    Medical condition: Pneumococcal colonisation post inoculation
    Disease: Version SOC Term Classification Code Term Level
    18.1 10042613 - Surgical and medical procedures 10059429 Influenza immunisation PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2020-001448-24 Sponsor Protocol Number: RG_20-029COVID-19 Start Date*: 2020-04-15
    Sponsor Name:University of Birmingham
    Full Title: Preventing Pulmonary Complications in Surgical Patients at Risk of COVID-19
    Medical condition: Preventing Pulmonary Complications in Surgical Patients at Risk of COVID-19
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10035664 Pneumonia PT
    21.1 100000004855 10003083 ARDS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2014-005462-30 Sponsor Protocol Number: MDCO-APO-14-01 Start Date*: 2016-10-26
    Sponsor Name:The Medicines Company
    Full Title: A multiple dose, dose-finding, placebo controlled, double blind, randomized trial to compare the effect of treatment on plaque burden as determined by intravascular ultrasound and evaluate the effi...
    Medical condition: acute coronary syndrome
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-001509-25 Sponsor Protocol Number: RHMCAN0860 Start Date*: 2012-09-25
    Sponsor Name:University Hospital Southampton NHS Foundation Trust
    Full Title: COAST - Cisplatin Ototoxicity attenuated by Aspirin Trial A randomised, Phase II, double-blind, placebo-controlled, two arm Trial to establish whether Aspirin can reduce hearing loss/ototoxicity fo...
    Medical condition: To establish whether Aspirin can reduce hearing loss/ototoxicity for patients receiving Cisplatin based chemotherapy.
    Disease: Version SOC Term Classification Code Term Level
    18.0 10013993 - Ear and labyrinth disorders 10033109 Ototoxicity PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-004785-98 Sponsor Protocol Number: OVG2008/5 Start Date*: 2008-12-22
    Sponsor Name:University of Oxford
    Full Title: An observational study of children immunised in infancy against hepatitis B virus, evaluating the persistence of immunity and the immune response to a scheduled booster dose of hepatitis B vaccine
    Medical condition: The intended application of Engerix B is active immunisation against Hepatitis B virus infection caused by all known subtypes in non immune subjects.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10052552 Hepatitis B virus LLT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-005616-29 Sponsor Protocol Number: FOCUS2012 Start Date*: 2012-02-03
    Sponsor Name:University of Edinburgh [...]
    1. University of Edinburgh
    2. NHS Lothian
    Full Title: A multicentre randomised trial to establish the effect(s) of routine administration of Fluoxetine for six months in patients with a recent stroke
    Medical condition: acute stroke
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029205 - Nervous system disorders 10061256 Ischaemic stroke PT
    14.1 10029205 - Nervous system disorders 10019016 Haemorrhagic stroke PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2012-004954-27 Sponsor Protocol Number: Start Date*: 2012-12-07
    Sponsor Name:Clinical Trials and Research Governance, University of Oxford
    Full Title: A single centre open-label randomised controlled trial of long term pituitary down-regulation before in vitro fertilisation for women with endometriosis: a pilot study
    Medical condition: Sub-infertility due to endometriosis
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004872 10016402 Female infertility of pituitary-hypothalamic origin LLT
    Population Age: Adults Gender: Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-000142-22 Sponsor Protocol Number: 148-2016 Start Date*: 2017-05-24
    Sponsor Name:Helm AG
    Full Title: Assessment of therapeutical equivalence of a newly developed vaginal tablet containing 10 μg of estradiol in comparison with a marketed reference product (Vagifem®) – a double-blind, double-dummy, ...
    Medical condition: Investigation of efficacy, safety and tolerability of estradiol vaginal tablets in postmenopausal women with vaginal atrophy
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004872 10047782 Vulvovaginal atrophy LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2004-001713-34 Sponsor Protocol Number: A3471119 Start Date*: 2005-01-11
    Sponsor Name:Pfizer Limited
    Full Title: RANDOMIZED, DOUBLE-BLIND, MULTICENTER STUDY OF THE EFFICACY, TOLERABILITY AND SAFETY OF VALDECOXIB (BEXTRA®)10 MG OD VS. DICLOFENAC SODIUM 50 MG TDS FOR 6 WEEKS IN SUBJECTS WITH OSTEOARTHRITIS OF T...
    Medical condition: Osteoarthritis of the knee
    Disease: Version SOC Term Classification Code Term Level
    10031161
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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