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Clinical trials for Orthopedic surgery

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44347   clinical trials with a EudraCT protocol, of which   7375   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    71 result(s) found for: Orthopedic surgery. Displaying page 2 of 4.
    « Previous 1  2  3  4  Next»
    EudraCT Number: 2022-000093-25 Sponsor Protocol Number: 01_20012022 Start Date*: 2022-05-05
    Sponsor Name:Aarhus University Hospital
    Full Title: The effect of lateral pectoral nerve block in combination with interscalene nerve block on opioid consumption and pain on awake shoulder arthroscopy patients - A feasibility study
    Medical condition: Peri- and postoperative pain after shoulder arthroscopy
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004848 10077421 Shoulder arthroscopy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2019-003850-10 Sponsor Protocol Number: Laxatives26092019 Start Date*: 2020-02-10
    Sponsor Name:Hospital Pharmacy Funen, Research Department, Odense University Hospital
    Full Title: Oral laxatives after hip fracture surgery: A randomised controlled trial.
    Medical condition: The aim is to investigate which constipation therapy is the most optimal choice for postoperative treatment in older patients after hip fracture surgery.
    Disease: Version SOC Term Classification Code Term Level
    23.0 10022117 - Injury, poisoning and procedural complications 10020100 Hip fracture PT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2012-001704-38 Sponsor Protocol Number: NL40000.072.012 Start Date*: 2012-06-14
    Sponsor Name:Sint Maartenskliniek
    Full Title: Effect of local anesthetic dose versus volume on block duration of single shot ultrasound-guided axillary brachial plexus block with mepivacaine
    Medical condition: Patients scheduled for single shot axillary brachial plexus block for hand, wrist, or forearm orthopedic surgery
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10038286 Regional nerve block LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2016-001511-20 Sponsor Protocol Number: 1 Start Date*: 2017-01-19
    Sponsor Name:Institute for Pharmacology and Toxicology
    Full Title: Pharmacokinetica of Cefuroxime
    Medical condition: hip or knee replacement or spine bone surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-022701-17 Sponsor Protocol Number: 1709801154 Start Date*: 2015-11-17
    Sponsor Name:Isala
    Full Title: Reduction of surgical-site infection in hip and knee arthroplasty: the influence of perioperative mupirocin nasal ointment and chlorhexidine soap in a double-blind, randomized, multicentre, placebo...
    Medical condition: osteoarthritis of hip and knee, prevention of surgical site infections after arthroplasty
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-004883-20 Sponsor Protocol Number: SM1-JH-16 Start Date*: 2017-02-01
    Sponsor Name:Ole Mathiesen
    Full Title: Does perineural dexmedetomidine prolong the duration of an ulnar nerve block when controlling for possible systemic effects? - a randomized, blinded, placebo controlled, paired trial in healthy vo...
    Medical condition: Healthy volunteers (treatment intended to improve regional anesthesia for orthopedic surgery)
    Disease: Version SOC Term Classification Code Term Level
    19.1 100000004863 10054711 Postoperative pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2019-004457-92 Sponsor Protocol Number: PB2452-PT-CL-0004 Start Date*: 2020-12-02
    Sponsor Name:SFJ Pharmaceuticals, Inc.
    Full Title: A Phase 3, Multicenter, Open-Label, Single-Arm Study of PB2452 in Ticagrelor-Treated Patients with Uncontrolled Major or Life-Threatening Bleeding or Requiring Urgent Surgery or Invasive Procedure ...
    Medical condition: Uncontrolled Major or Life Threatening Bleeding or Requiring Urgent Surgery or Invasive Procedure
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004865 10053756 Invasive procedure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) GB (GB - no longer in EU/EEA) BE (Completed) AT (Completed) NL (Completed) DE (Completed) IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-000062-35 Sponsor Protocol Number: ThereIsNoSponsorInvolved Start Date*: 2011-04-05
    Sponsor Name:Mikko Pitkänen, MD, PhD
    Full Title: Artikaiini 40mg ja kloroprokaiini 40 mg päiväkirurgisina spinaalipuudutteina (Lyhenne: A40C40)
    Medical condition: Knee arthroscopy performed as day case surgery
    Disease: Version SOC Term Classification Code Term Level
    12.1 10054948 Meniscus operation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: View results
    EudraCT Number: 2010-019669-27 Sponsor Protocol Number: 121 Start Date*: 2010-04-30
    Sponsor Name:University of Tartu
    Full Title: Hypobaric vs hyperbaric bupivacaine for spinal anaesthesia in total knee arthroplasty
    Medical condition: Orthopedic surgery patients with elective total knee arthroplasty
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: EE (Completed)
    Trial results: View results
    EudraCT Number: 2020-004920-40 Sponsor Protocol Number: AFFECT Start Date*: 2021-03-22
    Sponsor Name:Vestre Viken HF
    Full Title: Affective effects of pre-surgery opioids (AFFECT): a randomized double-blind controlled trial
    Medical condition: Healthy adult surgery patients. Health status ASA1 or ASA2 as categorised by a medical doctor at the hospital based on medical history, physical examination. The American Society of Anesthesiologis...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NO (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-019591-67 Sponsor Protocol Number: 1008032 Start Date*: 2010-06-01
    Sponsor Name:CHU de SAINT-ETIENNE
    Full Title: Pain assessment during general anesthesia : DOLANS Study
    Medical condition: perioperative analgesia
    Disease: Version SOC Term Classification Code Term Level
    12.1 10054799 Perioperative analgesia LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2022-001282-12 Sponsor Protocol Number: NVD003-CLN02-CPT Start Date*: 2022-08-02
    Sponsor Name:Novadip Biosciences
    Full Title: A proof-of-concept study with NVD-003, an autologous osteogenic bone graft, in the treatment of congenital pseudarthrosis of the tibia in pediatric patients
    Medical condition: congenital pseudarthrosis of the tibia (CPT)
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: BE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2007-001559-20 Sponsor Protocol Number: 95195608 Start Date*: 2007-04-17
    Sponsor Name:Cliniques Universitaires Saint-Luc
    Full Title: Steady-state pharmacokinetics of high dose acetaminophen inpost-op children. Rational use of N-acetyl cysteine for prevention of liver toxicity related to cumulative doses.
    Medical condition: Major surgery when the use of paracetamol is required for pain release
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: BE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-001518-26 Sponsor Protocol Number: DFI10569 Start Date*: 2009-03-30
    Sponsor Name:sanofi-aventis recherche & développement
    Full Title: Efficacy and safety of oral ataciguat (HMR1766) 200 mg administered once daily for 28 days on pain reduction in patients with Neuropathic Pain. A randomized, double-blind, placebo-controlled, cross...
    Medical condition: The proposed study is planned to demonstrate that ataciguat 200 mg/day could be effective in reducing neuropathic pain with a good safety profile
    Disease: Version SOC Term Classification Code Term Level
    9.1 10054095 Neuropathic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) CZ (Completed) DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2022-003885-19 Sponsor Protocol Number: NOT-APPLICABLE-HUFA Start Date*: 2023-03-15
    Sponsor Name:NO-COMERCIAL
    Full Title: ECOGUIDED GENICULAR NERVE BLOCK IN PATIENTS WITH KNEE OSTEOARTHRITIS BY LOCAL ANESTHETIC OR BY COMBINATION OF LOCAL ANESTHETIC AND CORTICOID: PLACEBO-CONTROLLED RANDOMIZED BLIND CLINICAL TRIAL
    Medical condition: KNEE OSTEOARTHRITIS
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-003537-15 Sponsor Protocol Number: TXA2018 Start Date*: 2019-02-18
    Sponsor Name:Medical University Vienna
    Full Title: Different dosing of Tranexamic Acid in patients undergoing elective total hip or knee arthroplasty. A randomized, controlled, double-blinded clinical trial.
    Medical condition: Blood loss in patients undergoing elective total hip or knee arthroplasty.
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004863 10053220 Hip injury LLT
    20.1 100000004863 10049032 Knee injury LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-003178-17 Sponsor Protocol Number: 0869-148 Start Date*: 2009-01-19
    Sponsor Name:Merck & Co., Inc.
    Full Title: Estudio multicéntrico de 2 partes para evaluar la farmacocinética, la seguridad y la tolerabilidad del aprepitant en pacientes pediátricos sometidos a una intervención quirúrgica. A Multicenter, 2-...
    Medical condition: Prevención de nauseas y vómitos postoperatorios en pacientes pediátricos. Prevention of Postoperative nausea and vomiting in pediatric patients.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10036901 Prophylaxis against postoperative nausea and vomiting LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: ES (Completed) FI (Completed) Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2022-001857-22 Sponsor Protocol Number: Methadone-010922 Start Date*: 2022-09-06
    Sponsor Name:Sygehus Sønderjylland, Orthopedic department
    Full Title: Perioperative Methadone for ameliorating postoperative pain and reduction in postoperative opioid consumption in hip fracture patients – Dosage adjusting pilot-study
    Medical condition: Hip fractures
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004863 10068399 Trochanteric femoral fracture LLT
    25.0 100000004863 10086938 Pertrochanteric femoral fracture LLT
    25.0 100000004863 10086939 Intertrochanteric femoral fracture LLT
    20.1 100000004863 10017284 Fractured femoral neck LLT
    20.1 100000004863 10053653 Femur fracture subtrochanteric LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2021-000242-17 Sponsor Protocol Number: Protocol_PPB_TKA_14012021 Start Date*: 2021-03-12
    Sponsor Name:Region Hospital Silkeborg
    Full Title: The effect of the popliteal plexus block on postoperative opioid consumption, pain, muscle strength and mobilization after total knee arthroplasty - a randomized, controlled, blinded study
    Medical condition: Postoperative pain following a total knee arthroplasty surgery
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004865 10036236 Postoperative pain relief LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2006-004638-33 Sponsor Protocol Number: 2006-122 Start Date*: 2006-11-21
    Sponsor Name:Department of Orthopedic Surgery, Aarhus University
    Full Title: Postoperative pain relief for primary total knee arthroplasty: A randomised clinical trial of local infiltration anaesthesia followed by intraaticulary infusion compared to epidural infusion
    Medical condition: Patients with Osteoarthrosis undergoing elective total knee arthroplasty (TKA)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
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