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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44380   clinical trials with a EudraCT protocol, of which   7392   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,380 result(s) found. Displaying page 211 of 2,219.
    EudraCT Number: 2006-004025-28 Sponsor Protocol Number: HTA 05-14-02 Start Date*: 2007-06-26
    Sponsor Name:Royal Liverpool Children’s NHS Trust
    Full Title: MENDS: The use of MElatonin in children with Neuro-developmental Disorders and impaired Sleep; a randomised, double-blind, placebo-controlled, parallel study
    Medical condition: children with neuro-developmental disorders and impaired sleep
    Disease: Version SOC Term Classification Code Term Level
    9.1 10064062 Neurodevelopmental disorder PT
    9.1 10040984 Sleep disorder PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-004036-71 Sponsor Protocol Number: 17-217 Start Date*: 2006-09-21
    Sponsor Name:Medizinische Universität Graz
    Full Title: Zur Frage des neuroleptikainduzierten metabolischen Syndroms. Studie 2: Fettverteilung und spezifische hormonelle Parameter. Vergleich zwischen auf das metabolische Syndrom vulnerablen und nicht vu...
    Medical condition: Bereits bekannte psychotische Erkrankung (Schizophrenie, schizoaffektive Störung, akut polymorph psychotische Störung) mit einer nicht tolerablen Gewichtssteigerung oder/und metabolischen Veränderu...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2006-001808-37 Sponsor Protocol Number: 612163 Start Date*: 2006-09-13
    Sponsor Name:Royal Devon and Exeter NHS Foundation Trust
    Full Title: A randomised controlled trial of fentanyl versus morphine following lower limb arthroplasty
    Medical condition: Patients with significant pain following hip or knee arthroplasty
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-001823-20 Sponsor Protocol Number: CMA-0601-PR-0004 Start Date*: 2006-06-22
    Sponsor Name:CHIESI
    Full Title: A twelve-week, multicentre, double blind, randomised, parallel group, clinical study to assess the antihypertensive efficacy of delapril 15 mg b.i.d. and 30 mg b.i.d. versus lisinopril and placebo
    Medical condition: hypertension
    Disease: Version SOC Term Classification Code Term Level
    9.1 10015488 Essential hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2007-002657-23 Sponsor Protocol Number: VX06-770-101 Start Date*: 2007-10-01
    Sponsor Name:Vertex Pharmaceuticals Incorporated
    Full Title: A Phase 2a, Randomized, Double-Blind, Placebo-Controlled Study of VX-770 to Evaluate Safety, Pharmacokinetics, and Biomarkers of CFTR Activity in Cystic Fibrosis (CF) Subjects with Genotype G551D
    Medical condition: cystic fibrosis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10011762 Cystic fibrosis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-000342-32 Sponsor Protocol Number: 248.642 Start Date*: 2009-02-17
    Sponsor Name:Boehringer Ingelheim Pharma GmbH & Co. KG
    Full Title: An open-label, flexible dose, follow-up study to evaluate safety and efficacy of oral pramipexole (0.0625-0.5 mg/day) for 24 weeks in children and adolescents (age 6-17 years) diagnosed with Touret...
    Medical condition: Tourette's Syndrome
    Disease: Version SOC Term Classification Code Term Level
    9.1 10044127 Tourette's syndrome LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2007-002376-34 Sponsor Protocol Number: CQAB149B2336 Start Date*: 2007-07-20
    Sponsor Name:NOVARTIS FARMA
    Full Title: A 26-week treatment, multi center, randomized, double blind, double dummy, placebo controlled, parallel group study to assess the efficacy and safety of indacaterol (150 μg o.d.) in patients w...
    Medical condition: COPD (CHRONIC OBSTRUCTIVE PULMONARY DISEASE)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10009026 Chronic obstructive airways disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed) DE (Completed) FI (Completed) HU (Completed) CZ (Completed) DK (Completed) IS (Completed) SK (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2007-004795-39 Sponsor Protocol Number: LSO-OL005 Start Date*: 2008-06-12
    Sponsor Name:Light Sciences Oncology Inc.
    Full Title: A Phase III Randomised Study to Evaluate Survival of Patients Treated with Talaporfin Sodium (LS11) and Interstitial Light Emitting Diodes (LED) as Compared to the Standard of Care Therapies in the...
    Medical condition: Patients with unresectable hepatocellular carcinoma
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10019828 Hepatocellular carcinoma non-resectable LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Completed) SE (Completed) IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-000202-36 Sponsor Protocol Number: CHUBX 2007/27 Start Date*: 2008-06-12
    Sponsor Name:CHU de Bordeaux
    Full Title: Etude clinique randomisée du propranolol versus placebo dans le traitement des hémangiomes capillaires infantiles.
    Medical condition: Hémangiomes capillaires
    Disease: Version SOC Term Classification Code Term Level
    9.1 10019386 Hemangioma LLT
    Population Age: Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-000219-14 Sponsor Protocol Number: 1957 Start Date*: 2008-03-19
    Sponsor Name:North Bristol NHS Trust
    Full Title: Efficacy of 8.4% sodium bicarbonate in adult patients with closed head injuries and intracranial hypertension.
    Medical condition: Raised intracranial pressure after severe head injury.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10022764 Intracranial hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2008-002079-28 Sponsor Protocol Number: 0724-018 Start Date*: 2008-10-30
    Sponsor Name:Merck & Co., Inc.
    Full Title: A Phase IIa Randomized, Double-Blind, Parallel-Groups, Placebo-Controlled Clinical Trial to Study the Efficacy and Safety of MK-0724 Intravenous Infusion on the Amelioration of Neurological Damage ...
    Medical condition: Middle cerebral artery ischemic stroke
    Disease: Version SOC Term Classification Code Term Level
    9.1 10055221 Ischemic stroke LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Prematurely Ended) AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-008359-40 Sponsor Protocol Number: CAIN457A2202 Start Date*: 2009-05-07
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A multicenter, randomised, double-blind, placebo-controlled, parallel-group proof- of-concept study to assess the efficacy, safety and tolerability of two single i.v. infusions of AIN457 10 mg/kg (...
    Medical condition: Moderate to severe Crohn's disease (CDAI = 220 and =450)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10011401 Crohn's disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) PL (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-003630-15 Sponsor Protocol Number: HypoAna Start Date*: 2007-03-06
    Sponsor Name:Steno Diabetes Center
    Full Title: The effect of insulin analogues and human insulin on the incidence of severe hypoglycae-mia in hypoglycaemia prone type 1 diabetic patients
    Medical condition: Type 1 diabetes - E10.8
    Disease: Version SOC Term Classification Code Term Level
    9.1 10012601 Diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-003650-20 Sponsor Protocol Number: V232-060-02 Start Date*: 2007-02-19
    Sponsor Name:Merck & Co Inc.,
    Full Title: A Study in Renal Predialysis and Dialysis Patients of the Safety, Tolerability, and Immunogenicity of Recombinant Hepatitis B Vaccine Manufactured with a Modified Process
    Medical condition: Hepatitis B
    Disease: Version SOC Term Classification Code Term Level
    8.1 10019731 Hepatitis B LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) ES (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2006-006112-30 Sponsor Protocol Number: P060210 Start Date*: 2008-07-09
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title: Etude multicentrique, randomisée, en double aveugle, évaluant l'efficacité du losartan versus placebo sur la dilatation de l'aorte chez des patients présentant un syndrome de Marfan
    Medical condition: Patients présentant un syndrome de Marfan traités par des béta bloquants
    Disease: Version SOC Term Classification Code Term Level
    8.1 10026829 syndrome Marfan PT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-002983-80 Sponsor Protocol Number: BY9010/M1-502 Start Date*: 2004-12-31
    Sponsor Name:ALTANA Pharma AG
    Full Title: Comparison of the Efficacy of a Fixed Combination of Ciclesonide and Formoterol versus a Fixed Combination of Fluticasone and Salmeterol
    Medical condition: asthma bronchiale
    Disease: Version SOC Term Classification Code Term Level
    5.1 10003553 llt
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2004-002985-39 Sponsor Protocol Number: ML18253 Start Date*: 2004-12-13
    Sponsor Name:ROCHE
    Full Title: A multicenter, randomized, controlled study comparing the efficacy and safety of 48 weeks of 40kD branched pegylated interferon alfa-2a (PEGASYS, Ro 25-8310) versus 96 weeks of PEGASYS, alone or in...
    Medical condition: Treatment of chronic hepatitis B, HBeAg-negative
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10019731 Hepatitis B PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2007-001486-15 Sponsor Protocol Number: TM-ME1207/311 Start Date*: 2007-08-02
    Sponsor Name:TEDEC-MEIJI FARMA, S.A.
    Full Title: Multicentre, prospective, comparative, randomized, double-blind, double-dummy study to assess the efficacy and safety of cefditoren pivoxil versus ciprofloxacin in acute uncomplicated cystitis. Est...
    Medical condition: Cistitis aguda no complicada en mujeres no embarazadas: patología caracterizada por disuria, dolor suprapúbico, polaquiuria y/o tenesmo en combinación con bacteriuria y piuria. Sin patología renal ...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10000699 Acute cystitis (excl in pregnancy) LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: ES (Completed) GR (Completed)
    Trial results: View results
    EudraCT Number: 2008-007478-39 Sponsor Protocol Number: 42160443NPP2001 Start Date*: 2009-10-07
    Sponsor Name:Janssen Cilag International, NV
    Full Title: A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Study to Evaluate the Efficacy, Safety, and Tolerability of JNJ-42160443 in Subjects With Postherpetic Neuralgia and Post-T...
    Medical condition: Postherpetic Neuralgia and Post-Traumatic Neuralgia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10029223 Neuralgia LLT
    9.1 10036376 Post herpetic neuralgia LLT
    9.1 10054095 Neuropathic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) NL (Prematurely Ended) ES (Completed)
    Trial results: View results
    EudraCT Number: 2006-006970-45 Sponsor Protocol Number: 2006.420/13 Start Date*: 2007-11-26
    Sponsor Name:Hospices Civils de Lyon
    Full Title: EVALUATION DE L’ASSOCIATION RADIOTHERAPIE DE CONFORMATION ET CHEMOEMBOLISATION INTRA-ARTERIELLE HEPATIQUE EN NEOADJUVANT DE LA RESECTION CHIRURGICALE DES CARCINOMES HEPATOCELLULAIRES DE GRANDE TAILLE
    Medical condition: Hepatocellular carcinoma respectable
    Disease: Version SOC Term Classification Code Term Level
    9.1 10019830 Hepatocellular carcinoma resectable LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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