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Clinical trials for Elderly

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44394   clinical trials with a EudraCT protocol, of which   7406   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    743 result(s) found for: Elderly. Displaying page 24 of 38.
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    EudraCT Number: 2004-002259-15 Sponsor Protocol Number: PCB305/04 Start Date*: 2005-01-24
    Sponsor Name:Photocure ASA
    Full Title: A RANDOMIZED, COMPARATIVE,CONTROLLED PHASE III, MULTICENTER STUDY OF HEXVIX FLUORESCENCE CYSTOSCOPY ANDWHITE LIGHT CYSTOSCOPY IN THE DETECTION OF PAPILLARY BLADDER CANCER AND THE EARLYRECURRENCE RA...
    Medical condition: Malignant neoplasm of bladder
    Disease: Version SOC Term Classification Code Term Level
    7.0 10046518 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2007-002682-12 Sponsor Protocol Number: ICORG 06-11 Start Date*: 2008-01-04
    Sponsor Name:ICORG
    Full Title: Protocol GI-04 A PHASE II TRIAL TO EVALUATE THE EFFICACY AND SAFETY OF BEVACIZUMAB IN COMBINATION WITH CAPECITABINE (XELODA) IN FRAIL PATIENTS WITH UNTREATED METASTATIC COLORECTAL CANCER
    Medical condition: FRAIL PATIENTS WITH UNTREATED METASTATIC COLORECTAL CANCER
    Disease: Version SOC Term Classification Code Term Level
    9.1 10052362 Metastatic colorectal cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Completed)
    Trial results: View results
    EudraCT Number: 2008-001310-24 Sponsor Protocol Number: 111631 Start Date*: 2008-05-30
    Sponsor Name:GlaxoSmithKline Biologicals
    Full Title: A Phase III, open, non-randomized, multi-centric, single dose study to assess immunogenicity and safety of Fluarix™ / Influsplit SSW® 2008/2009 injected intramuscularly in young adults (18 to 60 ye...
    Medical condition: Immunization against influenza of healthy adults.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-015974-36 Sponsor Protocol Number: REC-ANZ Start Date*: 2009-09-28
    Sponsor Name:G.I.S.L. - GRUPPO ITALIANO STUDIO LINFOMI
    Full Title: Phase II prospective study on high dose myeloablative therapy, with peripheral stem cell support, in elderly patients (>=65 e <76 years) with aggressive relapsed or refractory non Hodgkin lymphoma
    Medical condition: Aggressive relapsed or refractory non Hodgkin lymphoma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10063908 LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-021071-83 Sponsor Protocol Number: FluvalAB-H-YL2010 Start Date*: 2010-08-12
    Sponsor Name:Omninvest Ltd.
    Full Title: Tolerability and Immunogenicity Study of FluvalAB Influenza Vaccine (trivalent, seasonal, active ingredient content: 15 μg HA/strain/0.5 mL) in Adults and Elderly Person
    Medical condition: Immunization of healthy people against influenza virus infections.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10059429 Influenza immunisation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: View results
    EudraCT Number: 2011-006278-15 Sponsor Protocol Number: IIBSP-FAT-2011-103 Start Date*: 2012-07-09
    Sponsor Name:Institut de Recerca Hospital de la Sant Creu i Sant Pau
    Full Title: Prevention of postoperative bleeding: A multicenter, randomized, parallel, controlled clinical trial, evaluating the efficacy of tranexamic acid and fibrin glue in patients undergoing interventions...
    Medical condition: Patient with a hip fracture and a prosthesis is needed.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-000607-16 Sponsor Protocol Number: V70_44S Start Date*: 2013-05-13
    Sponsor Name:Novartis Vaccines and Diagnostics S.r.l.
    Full Title: A Phase II, Open-Label, Single-Arm, Multicenter Study to Evaluate the Safety and Immunogenicity of a Trivalent, Surface Antigen Inactivated Subunit Influenza Virus Vaccine Including MF59C.1 Adjuvan...
    Medical condition: Influenza
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2016-004250-15 Sponsor Protocol Number: Start Date*: 2018-06-08
    Sponsor Name:University Hospitals Birmingham
    Full Title: A prospective, phase II, single centre, cross-sectional, randomised trial investigating Dehydroepiandrosterone and it's Pharmacokinetics in Trauma
    Medical condition: DHEA depletion in trauma and hip fracture patients.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10022891 - Investigations 10056629 Dehydroepiandrosterone decreased PT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2005-003475-20 Sponsor Protocol Number: S1543016 Start Date*: 2006-05-25
    Sponsor Name:Solvay Pharmaceuticals, Inc
    Full Title: A Randomized, Double-Blind, Placebo-Controlled, Efficacy, Safety and Tolerability Study of Bifeprunox in the Treatment of Elderly Subjects with Psychosis and Behavioural Disturbances Associated wit...
    Medical condition: Dementia of the Alzheimer's type (DSM-IV TR) code 294.11
    Disease: Version SOC Term Classification Code Term Level
    10012271
    Population Age: Elderly Gender: Male, Female
    Trial protocol: EE (Prematurely Ended) CZ (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2006-000287-84 Sponsor Protocol Number: 101 Start Date*: 2006-07-11
    Sponsor Name:Sykehuset Innlandet HF
    Full Title: Seponering av antipsykotika og antidepressiva hos demente pasienter med APSD i sykehjem - en åpen studie.
    Medical condition: The included patients are all elderly people with dementia of Alzheimer or vascular type. Their dementia is moderate or severe and they all have Behavioral or Psychological Symptomes (BPSD).
    Disease: Version SOC Term Classification Code Term Level
    8.1 10057678 Vascular dementia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-004925-64 Sponsor Protocol Number: Cola Start Date*: 2008-05-28
    Sponsor Name:HSK Research GmbH
    Full Title: A Phase II Controlled Study of pegylated liposomal Doxorubicin (PLD, CAELYX) and Carboplatin for the Preoperative Treatment of Advanced Breast Cancer
    Medical condition: A PLD and Carboplatin based neoadjuvant treatment regimen with less cardiotoxicity (as compared to other anthracyclines) and generally reduced side effects is of interest not only for breast cancer...
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-011742-26 Sponsor Protocol Number: TetDip-2009 Start Date*: 2009-04-14
    Sponsor Name:Institute for Biomedical Aging Research
    Full Title: Humoral and cellular immune response against tetanus and diphtheria following booster vaccination
    Medical condition: This study will analyze cellular and humoral immune responses after booster vaccination. Healthy adults are vaccinated against tetanus, diphtheria, pertussis and polio on a regular basis. This stud...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10039244 Routine vaccination LLT
    9.1 10054183 Tetanus immunization LLT
    9.1 10054180 Diphtheria immunization LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-005116-12 Sponsor Protocol Number: CRAD001C2428 Start Date*: 2008-03-20
    Sponsor Name:Technical University of Munich
    Full Title: Phase II study of the mTOR-Inhibitor EVEROLIMUS as maintenance therapy in patients aged over 60 years with Mantle Cell Lymphoma (MCL) after first, second, third or fourth line chemotherapy New ...
    Medical condition: Strategies to prolong remission duration in elderly patients with MCL are urgently needed. The effects of Rapamycin derivates on MCL cells in vitro and the evolving in vivo data support the furthe...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-003205-10 Sponsor Protocol Number: 12072 Start Date*: 2012-09-17
    Sponsor Name:University of Nottingham
    Full Title: A randomised placebo controlled trial of follow on Rifaximin for the prevention of relapse of Clostridium difficile associated diarrhoea.
    Medical condition: C.Difficile antibiotic-associated diarrhoeal infection
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-003081-18 Sponsor Protocol Number: BRD/07/137 Start Date*: 2008-09-29
    Sponsor Name:University College Hospital
    Full Title: Phase II study of low intensity allogeneic transplantation in Mantle Cell Lymphoma
    Medical condition: Mantle Cell Lymphoma (MCL) is an increasingly recognised yet rare sub-type of non-hodgkin's Lymphoma (NHL), representing between 5 and 8% of all cases. Typically a disease of the elderly with a me...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2016-002827-27 Sponsor Protocol Number: EMI-137-CRC-001 Start Date*: 2016-12-16
    Sponsor Name:Edinburgh Molecular Imaging Ltd.
    Full Title: A Phase IIb, Open Label Study for the Detection of Dysplastic Colorectal Polyps during Colonoscopy after EMI-137 Injection in Patients with High Suspicion of Colorectal Cancer.
    Medical condition: Dysplastic Colorectal Polyps
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10029104 Neoplasms benign, malignant and unspecified (incl cysts and polyps) SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-005102-42 Sponsor Protocol Number: INTERIM 0407 Start Date*: 2007-12-19
    Sponsor Name:AZIENDA OSPEDALIERA SPEDALI CIVILI DI BRESCIA
    Full Title: Phase II explorative study of intermittent Imatinib (IM) treatment (INTERIM) in elderly patients with Ph+ chronic myeloid leukemia (CML) who achieved a stable complete cytogenetic response (CCgR) w...
    Medical condition: Patients with CML Ph+ CP that are in cytogentic response complete and stable for the last two years, treated with a Glivec daily dose
    Disease: Version SOC Term Classification Code Term Level
    9.1 10009014 Chronic myeloid leukaemia (in remission) LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-017688-40 Sponsor Protocol Number: GID34 Start Date*: 2010-04-16
    Sponsor Name:Sanofi Pasteur SA
    Full Title: Immunogenicity and Safety of the Influenza Vaccine (Split Virion, Inactivated), Northern Hemisphere 2010-2011 Formulation (Intradermal Route)
    Medical condition: Vaccination of adults up to 59 years of age and elderly of 60 years of age and over with inactivated split-virion influenza vaccine administered by the intraderma route
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2014-003599-21 Sponsor Protocol Number: MEIXO-VALV-002 Start Date*: 2015-06-27
    Sponsor Name:Sociedad Española de Cardiología
    Full Title: Platelet reactivity after TAVI: A multicenter randomized clinical trial
    Medical condition: Study platelet reactivity in patients with Aortic Stenosis (AS) selected for TAVI and to assess the effectiviness of ticagrelor as antiplatelet monotherapy for the supression of high platelet react...
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-006658-24 Sponsor Protocol Number: 8024 Start Date*: 2009-03-05
    Sponsor Name:University of Nottingham
    Full Title: A randomised controlled trial to compare the safety and effectiveness of doxycycline (200 mg/day) with prednisolone (0.5 mg/kg/day) for initial treatment of bullous pemphigoid
    Medical condition: BP is a serious condition with a significant associated morbidity and mortality rate. Widespread tense and haemorrhagic blisters, skin erosions and severe itching cause patients a great deal of dis...
    Disease: Version SOC Term Classification Code Term Level
    14.0 10040785 - Skin and subcutaneous tissue disorders 10006568 Bullous pemphigoid NOS LLT
    14.0 10040785 - Skin and subcutaneous tissue disorders 10006567 Bullous pemphigoid LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) DE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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