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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44358   clinical trials with a EudraCT protocol, of which   7384   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,358 result(s) found. Displaying page 305 of 2,218.
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    EudraCT Number: 2007-007160-19 Sponsor Protocol Number: CAEB071C2201 Start Date*: 2009-03-13
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A double blind, randomized, placebo controlled, multicenter, dose finding study of oral AEB071 assessing Psoriasis Area and Severity Index (PASI) respoonse as a function of dose and treatment durat...
    Medical condition: Plaque psoriasis diagnosed for at least 12 months with or without psoriatic arthritis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) IT (Completed) GB (Completed) BE (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-004603-35 Sponsor Protocol Number: REACH Start Date*: 2009-04-28
    Sponsor Name:University of Heidelberg
    Full Title: Radiotherapy (IMRT), Erbitux And Chemotherapy For Unresectable Carcinomas Of Head and Neck. REACH-Study
    Medical condition: Histologically confirmed locally advanced (stage III or IV), non-metastatic squamous cell carcinoma of oro-, hypopharynx or larynx (T2-4, NX, M0).
    Disease: Version SOC Term Classification Code Term Level
    9.1 10041849 Squamous cell carcinoma of the hypopharynx LLT
    9.1 10023856 Laryngeal squamous cell carcinoma LLT
    9.1 10031112 Oropharyngeal squamous cell carcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2004-005112-83 Sponsor Protocol Number: Short1/4-INF-RIBA Start Date*: 2005-02-10
    Sponsor Name:AZIENDA SANITARIA OSPEDALIERA S. GIOVANNI BATTISTA DI TORINO
    Full Title: RANDOMISED CONTROLLED STUDY ON EARLY RESPONSE TO COMBINED ANTIVIRAL THERAPY IN CHRONIC EPATITES C PATIENT GENOTIPE 1 AND 4 WITH HCV RNA NEGATIVE WEEK 6
    Medical condition: SOSTAINED BIOCHEMICAL AND VIROLOGICAL RESPONSE TO COMBINATED THERAPY PEGILATED RIBAVIRIN IN CHRONIC EPATITIES PATIENTS G 1 AND 4
    Disease: Version SOC Term Classification Code Term Level
    6.1 10019663 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-002122-10 Sponsor Protocol Number: RDR342 Start Date*: 2008-10-17
    Sponsor Name:RDR Pharma GmbH
    Full Title: Comparison of the Clinical Efficacy and Tolerability of Latanoprost RDR 0.005% Eye Drops Test Formulation of RDR Pharma GmbH, Germany, for the Treatment of Ocular Hypertension and Primary Open Angl...
    Medical condition: Ocular Hypertension (IOP>22 mmHg), Primary Open Angle Glaucoma (mean defect between 0 and -12 db in a visual field)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10030043 Ocular hypertension LLT
    9.1 10036719 Primary open angle glaucoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) LT (Prematurely Ended) BG (Completed) LV (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-001918-33 Sponsor Protocol Number: 107507 Start Date*: 2006-06-23
    Sponsor Name:GlaxoSmithKline Biologicals
    Full Title: A Phase III study for evaluation of immunogenicity and reactogenicity of Fluarix™ (Influspit SSW®) 2006/2007 in people aged 18 years or above
    Medical condition: immunization against influenza of healthy adults
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-001938-41 Sponsor Protocol Number: H8O-SB-GWBN(a) Start Date*: 2007-02-07
    Sponsor Name:Lilly Deutschland GmbH
    Full Title: Effect of Exenatide plus Metformin vs. Premixed Human Insulin Aspart plus Metformin on Glycemic Control and Hypoglycemia in Patients with Inadequate Control of Type 2 Diabetes on Oral Antidiabetic ...
    Medical condition: Type 2 Diabetes mellitus
    Disease: Version SOC Term Classification Code Term Level
    8.1 10045242 Type II diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-001947-70 Sponsor Protocol Number: MBP8298-RR-01 Start Date*: 2006-09-14
    Sponsor Name:BioMS Technology Corp.
    Full Title: A Double Blind, Placebo Controlled Multi-Center Pilot Study to Evaluate the Efficacy and Safety of MBP8298 in Relapsing Remitting Multiple Sclerosis
    Medical condition: Relapsing Remitting Multiple Sclerosis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-005746-36 Sponsor Protocol Number: D1532C00008 Start Date*: 2007-01-19
    Sponsor Name:AstraZeneca AB
    Full Title: A Phase II, Open, Randomised Study to Assess the Efficacy and Safety of AZD6244 vs. capecitabine (Xeloda) in Patients with Advanced or Metastatic Pancreatic Cancer, who have Failed First Line gemci...
    Medical condition: Advanced or Metastatic Pancreatic Cancer
    Disease: Version SOC Term Classification Code Term Level
    8.1 10033605 Pancreatic cancer metastatic LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: View results
    EudraCT Number: 2007-005525-29 Sponsor Protocol Number: P070115 Start Date*: 2009-07-31
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title: Traitement in utero de l’infection congénitale à cytomegalovirus (CMV) par valaciclovir : essai prospectif randomisé contre placebo
    Medical condition: L'infection par cytomégalovirus chez la femme enceinte.
    Disease: Version SOC Term Classification Code Term Level
    8.1 10011828 L'Infection à Cytomégalovirus PT
    Population Age: Adults Gender: Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-005951-40 Sponsor Protocol Number: ITHACA Start Date*: 2008-02-07
    Sponsor Name:Fundació Lluita contra la Sida
    Full Title: DINAMICA VIRAL DEL VIH-1 EN SUJETOS QUE INICIAN TERAPIA CON RALTEGRAVIR (HIV-1 VIRAL DYNAMICS IN SUBJECTS INITIATING RALTEGRAVIR THERAPY)
    Medical condition: Pacientes con infección VIH-1 (HIV-1 infection)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10000807 Acute HIV infection LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2007-006073-84 Sponsor Protocol Number: MD7108240 Start Date*: 2008-02-25
    Sponsor Name:GlaxoSmithKline Research and Development
    Full Title: A double-masked, randomized, parallel-group study to investigate the pharmacodynamics, safety, and systemic pharmacokinetics of pazopanib eye drops, administered for 28 days to adult subjects with ...
    Medical condition: Neovascular age-related macular degeneration
    Disease: Version SOC Term Classification Code Term Level
    9.1 10025409 Macular degeneration LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2007-006085-15 Sponsor Protocol Number: VIAjectTM-09J Start Date*: 2008-03-14
    Sponsor Name:Biodel Inc.
    Full Title: An Open Label, Multi-Center, Follow-on Study Examining the Long- Term Safety and Efficacy of Insulin VIAject™ in Subjects with Type 2 Diabetes Mellitus
    Medical condition: Diabetes Mellitus Type 2
    Disease: Version SOC Term Classification Code Term Level
    9.1 10045242 Type II diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-006935-29 Sponsor Protocol Number: 19.4.328 Start Date*: 2008-06-12
    Sponsor Name:NV Organon
    Full Title: A multi-center, parallel-group, comparative trial evaluating the efficacy, pharmacokinetics and safety of 4.0 mg.kg-1 sugammadex administered at 1-2 PTC in subjects with normal or severely impaired...
    Medical condition: Not applicable
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) GB (Completed) NL (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2007-007015-89 Sponsor Protocol Number: CUV011 Start Date*: 2008-11-07
    Sponsor Name:Clinuvel Pharmaceuticals Limited
    Full Title: A Multicentre, Randomised, Double-Blind, Placebo-Controlled Phase II Study to Evaluate the Safety and Efficacy of Subcutaneous Bioresorbable Implants of CUV1647 for the Prophylactic Treatment of Pr...
    Medical condition: Pre-cancerous skin lesions
    Disease: Version SOC Term Classification Code Term Level
    9.1 10000614 Actinic keratosis LLT
    9.1 10004146 Basal cell carcinoma LLT
    9.1 10041823 Squamous cell carcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) BE (Completed) FR (Ongoing) DE (Completed) IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-007033-40 Sponsor Protocol Number: SIOVAC Start Date*: 2008-02-21
    Sponsor Name:Fundación para La Investigación Biomedica del Hospital Gregorio Marañón
    Full Title: Estudio SIOVAC (Sildenafilo en Pacientes con Hipertensión Pulmonar tras Corrección de la Enfermedad Valvular)
    Medical condition: Pacientes con Hipertensión Pulmonar Secundaria a enfermedad valvular cardiaca
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-007043-27 Sponsor Protocol Number: 111454 Start Date*: 2008-02-21
    Sponsor Name:GlaxoSmithKline Biologicals
    Full Title: A phase II, double-blind, multicentre, randomized study to demonstrate the non-inferiority of GlaxoSmithKline Biologicals’ thiomersal-free adjuvanted influenza vaccine compared to GlaxoSmithKline B...
    Medical condition: Immunization against influenza in male and female subjects aged >/= 65 years.
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: EE (Completed)
    Trial results: View results
    EudraCT Number: 2007-007062-38 Sponsor Protocol Number: EC07/90316 Start Date*: 2008-04-22
    Sponsor Name:Fundación Investigación Biomédica Hospital General Universitario Gregorio Marañón (FIBHGUGM)
    Full Title: “Necesidad de tratamiento antibiótico de la bacteriemia relacionada con catéteres venosos centrales producida por Staphylococcus coagulasa-negativa tras la retirada del catéter en pacientes de bajo...
    Medical condition: Estudiar la necesidad de tratamiento antibiótico en pacientes con BRC por SCN, con bajo riesgo de desarrollo de complicaciones, tras la retirada de dichos catéteres. To study need for antimicrobia...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-007063-24 Sponsor Protocol Number: EC07/90653 Start Date*: 2009-09-25
    Sponsor Name:Fundación Investigación Biomédica Hospital General Universitario Gregorio Marañón (FIBHGUGM)
    Full Title: “Estudio de la terapia de cierre con etanol en la prevención de la infección relacionada con catéteres venosos centrales no tunelizados de corta duración” “Clinical study of ethanol lock-therapy i...
    Medical condition: Estudiar el valor de la terapia de cierre con etanol en la prevención de la IRC en catéteres venosos centrales de corta duración de pacientes ingresados en una unidad de cuidados intensivos post-ci...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10051387 Catheter infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-003444-53 Sponsor Protocol Number: CSMS995BIT12 Start Date*: 2005-10-11
    Sponsor Name:NOVARTIS FARMA
    Full Title: A randomised, open label, multicenter study comparing the efficacy and safety of medical treatment with Sandostatin LAR 30 mg administered every 21 days for 6 months with that of Sandostatin LAR 60...
    Medical condition: Treatment of acromegalic patients partially responsive to somatostatin analogues
    Disease: Version SOC Term Classification Code Term Level
    6.1 10000599 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2008-002221-36 Sponsor Protocol Number: 28779 Start Date*: 2008-10-17
    Sponsor Name:Merck Serono International, An affiliate of Merck KGaA, Darmstadt, Germany
    Full Title: A Phase II/III, randomized, double-blind, placebo-controlled trial to evaluate the safety and efficacy of atacicept in combination with corticosteroids and sequential therapy with cyclophosphamide ...
    Medical condition: Lupus Nephritis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10025140 Lupus nephritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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