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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44349   clinical trials with a EudraCT protocol, of which   7376   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,349 result(s) found. Displaying page 328 of 2,218.
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    EudraCT Number: 2007-007694-23 Sponsor Protocol Number: 593 Start Date*: 2008-07-28
    Sponsor Name:Forschergruppe Diabetes e. V.
    Full Title: Transfusion of Autologous Umbilical Cord Blood to Reverse Hyperglycemia in Children with Type 1 Diabetes - A Pilot Study
    Medical condition: Type 1 Diabetes
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-007699-40 Sponsor Protocol Number: C3BS-C-07-1 Start Date*: 2009-02-25
    Sponsor Name:Cardio3 BioSciences
    Full Title: C-Cure - Safety, feasibility and efficacy of guided bone marrow-derived cardiopoietic mesenchymal stem cells for the treatment of heart failure secondary to ischemic cardiomyopathy
    Medical condition: C-Cure is indicated for the treatment of heart failure (NYHA class II and III with a Left Ventricular Ejection Fraction > 15 % and <= 40%) secondary to ischemic cardiomyopathy.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10064081 Heart failure NYHA class III LLT
    9.1 10064080 Heart failure NYHA class II LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-003962-40 Sponsor Protocol Number: S043VELC02 Start Date*: 2006-03-22
    Sponsor Name:FONDAZIONE SENDO
    Full Title: An open label, Phase II study of biweekly VELCADETM and intermittent CAELIXTM in patients with ovarian cancer failing platinum containing regimens
    Medical condition: ovarian cancer failing platinum containing regimens
    Disease: Version SOC Term Classification Code Term Level
    9.1 10061535 Ovarian neoplasm LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-005708-18 Sponsor Protocol Number: 14081962 Start Date*: 2010-06-04
    Sponsor Name:Queen Mary University of London
    Full Title: Prevention of metabolic complications of glucocorticoid excess
    Medical condition: Rheumatoid arthritis, SLE, Polymyalgia rheumatica, Disthyroid eye disease, Cushing's syndrome
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-005746-22 Sponsor Protocol Number: AECUDATT Start Date*: 2009-05-05
    Sponsor Name:Allergie-Centrum-Charite, Department of Dermatology, Charite - Universitätsmedizin Berlin
    Full Title: Multi-center, double blind, dose escalating study to compare the effects of 5 mg, 10mg and 20mg of Desloratadine in patients with acquired cold urticaria (ACU)
    Medical condition: Chronic urticaria is characterized by the spontaneous development of wheal and flare type skin reactions.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10009869 Cold urticaria LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-004487-39 Sponsor Protocol Number: CM-001 Start Date*: 2008-11-25
    Sponsor Name:ISTITUTO GIANNINA GASLINI
    Full Title: Spontaneous monocentric study phase II: salvage therapy with clofarabine in combination with other cytotoxic agentsfor the treatment of resistent leukemia in children
    Medical condition: Acute Leukemia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10000830 Acute leukaemia LLT
    Population Age: Newborns, Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-004492-21 Sponsor Protocol Number: CIOCC012008 Start Date*: 2008-10-07
    Sponsor Name:Fundación Hospital de Madrid
    Full Title: Estudio biológico del efecto de GW572016 (Lapatinib) en la apoptosis celular en el Carcinoma Ductal in Situ en pacientes con cáncer de mama HER2 positivo
    Medical condition: Cancer de mama
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-004496-22 Sponsor Protocol Number: 13273 Start Date*: 2008-11-13
    Sponsor Name:Bayer Health Care AG
    Full Title: Prospective non-randomized (pharmacoepidemiologic) cohort study (open-label, multicenter) to assess the magnitude of potential risk with the administration of Gadovist® in patients with moderate to...
    Medical condition: Patients with moderate to severe renal impairment.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10038359 - Renal and urinary disorders 10038469 Renal impairment NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2008-004504-31 Sponsor Protocol Number: 0822-031 Start Date*: 2008-09-16
    Sponsor Name:Merck Sharp & DOhme (Sweden) AB
    Full Title: A Phase III Randomized, Placebo-Controlled Study to Evaluate the Effect of Odanacatib (MK-0822) on Bone Mineral Density (BMD) and Overall Safety, and to Estimate the Effect of Odanacatib (MK-0822) ...
    Medical condition: low BMD (bone mineral density)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10032364 Other osteoporosis LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: SE (Prematurely Ended) FR (Completed) DK (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-003669-18 Sponsor Protocol Number: SVS/K/00604 Start Date*: 2006-11-15
    Sponsor Name:Seven Seas Limited
    Full Title: Efficacy an tolerability of a combinatzion of glucosamine sulphate and the tw omega-3 unsaturated fatty acids EPA and DHA in comparison to glucosamine sulphate in patients with ostearthritis
    Medical condition: Osteoarthritis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-002319-16 Sponsor Protocol Number: Pr LEVY - PCa - CPRC 2006 Start Date*: 2007-09-07
    Sponsor Name:Centre Hospitalier Universitaire de Nancy
    Full Title: Modulation de la vasoréactivité dans le choc septique : impact de la protéine C recombinante
    Medical condition: sepsis : sont inclus les patients répondant aux critères conventionnels du choc septique qui intègrent ceux d’infection et d’infection sévère
    Disease: Version SOC Term Classification Code Term Level
    9.1 10040047 Sepsis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-002334-11 Sponsor Protocol Number: 12014A Start Date*: 2009-03-13
    Sponsor Name:H. Lundbeck A/S
    Full Title: Nalmefene Efficacy Study I: Randomised, double-blind, placebo-controlled, parallel-group, efficacy study of 20 mg nalmefene, as needed use, in patients with alcohol dependence
    Medical condition: Alcohol dependence
    Disease: Version SOC Term Classification Code Term Level
    9.1 10001594 Alcohol dependence syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) SE (Completed) FI (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-002359-18 Sponsor Protocol Number: PEDVAC Start Date*: 2008-04-23
    Sponsor Name:Swedish Institute for Infectious Disease Control
    Full Title: DNA vaccination in HIV-vertically infected children
    Medical condition: Pazienti con infezione verticale da HIV di eta' compresa tra 4 -16 anni di ambo i sessi.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10053500 Human immunodeficiency virus transmission LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-002556-41 Sponsor Protocol Number: TRX 1.0 Start Date*: 2008-02-07
    Sponsor Name:Trimed Biotech GmbH
    Full Title: A randomized, open-label, 2-arm, multicentre, Phase II study to evaluate the safety and efficacy of Trivax, a dendritic cell-based interleukin-12 secreting autologous cancer vaccine, in combination...
    Medical condition: Metastatic renal cell carcinoma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10050513 Metastatic renal cell carcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) CZ (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-002557-23 Sponsor Protocol Number: ATH001-CLN01 Start Date*: 2007-11-02
    Sponsor Name:Advancell Advanced In Vitro Cell Technologies, S.A
    Full Title: A Phase I/II Open-Label Dose Escalation Study to Investigate the Safety and Tolerability of Acadesine in Patients with B-Cell Chronic Lymphocytic Leukaemia
    Medical condition: Patients with B-Cell Chronic Lymphocytic Leukemia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003892 B-cell chronic lymphocytic leukaemia/prolymphocytic leukaemia/small lymphocytic lymphoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) FR (Ongoing) ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-007538-21 Sponsor Protocol Number: CYR-101C01 Start Date*: 2008-04-22
    Sponsor Name:CYRENAIC
    Full Title: A Multi-center, Inpatient and ambulatory, Phase 2, Double-blind, Randomised, Placebo-controlled Proof of Concept Study of CYR-101 in Patients with DSM-IV Schizophrenia
    Medical condition: Diagnosis of Schizophrenia in Male or female patients, as defined in Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition Text Revised (DSM-IV TR, APA 2000) and confirmed by the St...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10039626 Schizophrenia LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-007555-14 Sponsor Protocol Number: C10953/2032/DP/US Start Date*: 2008-08-15
    Sponsor Name:Cephalon, Inc.
    Full Title: An 8-Week, Double-Blind, Placebo-Controlled, Parallel-Group, Fixed-Dosage Study to Evaluate the Efficacy and Safety of Armodafinil Treatment (150 mg/day) as Adjunctive Therapy in Adults With Major ...
    Medical condition: Major Depression Associated With Bipolar I Disorder
    Disease: Version SOC Term Classification Code Term Level
    9.1 10057840 Major depression LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: HU (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2005-004309-27 Sponsor Protocol Number: P04579 Start Date*: 2005-12-28
    Sponsor Name:Schering Plough Research Institute
    Full Title: Cross-Over Study of the Decongestant Effect of Phenylephrine Compared With Placebo and Pseudoephedrine as Active Control in SAR Subjects Exposed to Pollen in the Vienna Challenge Chamber
    Medical condition: Seasonal Allergic Rhinitis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2008-002724-29 Sponsor Protocol Number: RC 48/07 Start Date*: 2011-10-26
    Sponsor Name:ISTITUTO PER L'INFANZIA BURLO GAROFOLO
    Full Title: Continuous peritoneal infusion of ropivacaine following laparoscopy for postoperative analgesia in children: a randomized, double-blind, placebo-controlled study.
    Medical condition: Children aged over 1 year, undergoing elective abdominal laparoscopic surgery.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10023693 Laparoscopy LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-004699-38 Sponsor Protocol Number: RCCC10 Start Date*: Information not available in EudraCT
    Sponsor Name:Klinikum der Universität Regensburg
    Full Title: A prospective phase I/II, one-arm, multi-center, open label study of pioglitazone in combination with sorafenib and low dose IFN alpha in metastatic, non-resectable renal clear cell carcinoma
    Medical condition: To investigate the effect of an anti-inflammatory therapy consisting of pioglitazone (Actos) in combination with an angiostatic treatment with sorafenib (Nexavar) and Interferin-Alpha (Roferon) on ...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10038416 Renal clear cell carcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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