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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44393   clinical trials with a EudraCT protocol, of which   7405   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,393 result(s) found. Displaying page 328 of 2,220.
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    EudraCT Number: 2007-001114-17 Sponsor Protocol Number: WA19923 Start Date*: 2007-12-12
    Sponsor Name:F. Hoffmann-La Roche Limited
    Full Title: A Mechanism of Action study to evaluate the effects of IL-6 receptor blockade with tocilizumab (TCZ) on lipids, arterial stiffness, and markers of atherogenic risk in patients with moderate to seve...
    Medical condition: Rheumatoid Arthritis (RA)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: Removed from public view
    EudraCT Number: 2007-001096-10 Sponsor Protocol Number: S308.3.009 Start Date*: 2008-03-27
    Sponsor Name:Solvay Pharmaceuticals
    Full Title: An Extension of the Van Gogh Study: An Open Label SLV308 Safety Extension to Study S308.3.004 in Patients with Parkinson’s Disease Experiencing Motor Fluctuations
    Medical condition: advanced stage of idiopathic PD with dose-dependent motor fluctuations.
    Disease: Version SOC Term Classification Code Term Level
    8.1 10013113 Disease Parkinson's LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Prematurely Ended) SK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-001009-41 Sponsor Protocol Number: grim1001 Start Date*: 2008-10-08
    Sponsor Name:Imperial College Healthcare NHS trust
    Full Title: mycophenylate mofetil and tacrolimus vs tacrolimus alone for the treatment of nephrotic syndrome secondary to idiopathic membranous glomerulonephritis
    Medical condition: Idiopathic Membranous Glomerulonephritis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10029167 Nephrotic syndrome with lesion of membranous glomerulonephritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-001865-28 Sponsor Protocol Number: 08/H0802/9 Start Date*: 2008-05-30
    Sponsor Name:King's College London [...]
    1. King's College London
    2. Guys and St Thomas NHS Foundation Trust
    Full Title: The Relationship between Osteoporosis and Aortic Calcification in Postmenopausal Women
    Medical condition: Osteoporosis; Aortic Calcification
    Disease: Version SOC Term Classification Code Term Level
    14.1 10047065 - Vascular disorders 10054208 Aortic calcification PT
    14.1 10028395 - Musculoskeletal and connective tissue disorders 10031285 Osteoporosis postmenopausal PT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-001743-21 Sponsor Protocol Number: BS 594 Start Date*: 2007-06-19
    Sponsor Name:Generics (UK) Ltd.
    Full Title: A PHASE II DOUBLE BLIND MODIFIED CROSS OVER DESIGN STUDY EVALUATING THE EFFICACY AND SAFETY OF TRIMETAZIDINE (GENERICS UK LIMITED) AND PLACEBO IN THE TREATMENT OF FIBROMYALGIA
    Medical condition: Fibromyalgia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10048439 Fibromyalgia LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-001744-53 Sponsor Protocol Number: PAI study Start Date*: 2008-04-02
    Sponsor Name:University of Leipzig
    Full Title: Open, randomized study for evaluation of an active Hepatitis B vaccination(HBVAXPRO) in combination with a passive immunisation with Hepatitis B immunoglobulins (Hepatect) for subjects, who did not...
    Medical condition: Hepatitis B immunization
    Disease: Version SOC Term Classification Code Term Level
    9.1 10054130 Hepatitis B immunisation LLT
    9.1 10054130 Hepatitis B immunisation PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-001782-15 Sponsor Protocol Number: IGG-FC-GR/DEX21P Start Date*: 2008-04-09
    Sponsor Name:ISTITUTO GIANNINA GASLINI
    Full Title: Efficacy and safety of Intra-erythrocytes dexamethasone in cystic fibrosis
    Medical condition: Cystic Fibrosis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10011762 Cystic fibrosis LLT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-005194-30 Sponsor Protocol Number: P-AD337-021 Start Date*: 2006-06-12
    Sponsor Name:Arakis Ltd.
    Full Title: A multi-centre, randomised, double-blind, placebo controlled, parallel group exploratory study to investigate the efficacy, safety and tolerability of AD 337 in the treatment of fibromyalgia in fem...
    Medical condition: Fibromyalgia
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-005217-38 Sponsor Protocol Number: DSHNHL2004-2 Start Date*: 2008-07-25
    Sponsor Name:German High Grade Non-Hodgkins Lymphoma group
    Full Title: Randomiseret forsøg der sammenligner 4 og 6 kemoterapicykler med CHOP (Cyklofosfamid, Doxorubicin, Vincristin og Prednison) i 21-dages intervaller, begge med 6 cykler immunterapi med monoklonalt an...
    Medical condition: Patients with untreated aggressive CD20+ Non-Hodgkin’s Lymphoma aged 18 to 60 years without major accompanying disorders with no risk factor according to IPI and no bulky disease (<7,5cm)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10003899 B-cell lymphoma PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed) IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-003913-28 Sponsor Protocol Number: CB-01-02/04 Start Date*: 2009-05-25
    Sponsor Name:COSMO TECHNOLOGIES LTD
    Full Title: Randomised, double-blind,multicentre,12 months extension study to evaluate the safety and the efficacy of daily Budesonide MMX 6mg vs placebo in the maintenance of remission in subjects with ulcera...
    Medical condition: Mild to moderate ulcerative colitis.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10045365 Ulcerative colitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-005530-21 Sponsor Protocol Number: AGO/2006/010 Start Date*: 2007-01-12
    Sponsor Name:University Hospital Gent
    Full Title: Comparison of dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) with gadofosveset trisodium (Vasovist, Schering, Berlin, Germany) to gadopentetate dimeglumine (GD-DTPA, Magnevist, Sche...
    Medical condition: Metastatic colorectal cancer
    Disease: Version SOC Term Classification Code Term Level
    8.1 10052362 Metastatic colorectal cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-005549-12 Sponsor Protocol Number: P060102 Start Date*: 2007-05-04
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title: Chimiothérapie par Témozolomide dans le traitement des glioblastomes supratentoriels des sujets de 70 ans et plus présentant un état fonctionnel altéré (IK<70).
    Medical condition: Patients de 70 ans et plus atteints de glioblastomes supratentoriels et présentant un état fonctionnel altéré.
    Disease: Version SOC Term Classification Code Term Level
    8.1 10018336 glioblastome PT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-005557-30 Sponsor Protocol Number: FB/PS/14/165/06 Start Date*: 2007-03-16
    Sponsor Name:Chiesi Farmaceutici S.p.A.
    Full Title: In-vivo deposition measurement of formoterol and beclomethasone after inhalation of a single dose of the combination Formoterol plus BDP HFA pMDI (Foster®, Chiesi) in healthy volunteers, asthmatic...
    Medical condition: The study is focused on asthma bronchiale and chronic obstructive pulmonary disease (COPD)
    Disease: Version SOC Term Classification Code Term Level
    8.1 10003553 Asthma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-005564-12 Sponsor Protocol Number: IASON Start Date*: 2007-05-25
    Sponsor Name:Laboratoire IASON
    Full Title: Imagerie fonctionnelle de l'hypoxie du cancer du col utérin par 18F-FETNIM TEP/TDM
    Medical condition: Quantification du degré d'hypoxie par mesure de la fixation du 18F-FETNIM par TEP/TDM avant traitement radio-chimiothérapeutique et après le prélèvement histologique.
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-005578-39 Sponsor Protocol Number: PKI108574 Start Date*: 2007-01-18
    Sponsor Name:GlaxoSmithKline
    Full Title: A randomised, double-blind, placebo-controlled study to explore the antidepressant properties of the P38a kinase inhibitor GW856553X 15mg compared to placebo in subjects with Major Depressive Disor...
    Medical condition: Major Depressive Disorder
    Disease: Version SOC Term Classification Code Term Level
    8.1 10025453 Major depressive disorder NOS LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: EE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-000506-36 Sponsor Protocol Number: 12213A Start Date*: 2009-03-13
    Sponsor Name:H. Lundbeck A/S
    Full Title: Randomised, double-blind, parallel-group, placebo-controlled, fixed-dose comparison study of escitalopram in combination with two fixed doses of gaboxadol to escitalopram in Major Depressive Disorder
    Medical condition: Major Depressive Disorder
    Disease: Version SOC Term Classification Code Term Level
    9.1 10025453 Major depressive disorder NOS LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2007-003171-39 Sponsor Protocol Number: PSD502-PE-004 Start Date*: 2007-12-07
    Sponsor Name:Plethora Solutions Ltd
    Full Title: A phase III, multi-centre, randomized, double-blind, placebo-controlled study, with open-label follow on, to evaluate the efficacy, safety and tolerability of PDS502 in subjects with Premature Ejac...
    Medical condition: Premature Ejaculation
    Disease: Version SOC Term Classification Code Term Level
    9.1 10036596 Premature ejaculation PT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: GB (Completed) HU (Completed) CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-007394-22 Sponsor Protocol Number: PK11195 Start Date*: 2008-05-22
    Sponsor Name:Imperial College London
    Full Title: The role of white and grey matter and meningeal inflammation in multiple sclerosis (MS) and clinically isolated syndromes (CIS) as quantified using [(11)C](R)-PK11195 positron emission tomography (...
    Medical condition: Multiple Sclerosis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10052785 Multiple sclerosis acute and progressive HLT
    Population Age: Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-003677-10 Sponsor Protocol Number: CSPP100AGB01 Start Date*: 2007-10-02
    Sponsor Name:Novartis Pharmaceuticals UK Ltd
    Full Title: A twelve week, randomized, double-blind, parallel-group multicentre study to evaluate the efficacy and safety of the combination of aliskiren/ramipril/amlodipine (300/10/10mg), compared to the com...
    Medical condition: patients with essential hypertension and metabolic syndrome.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-003277-19 Sponsor Protocol Number: nd Start Date*: 2007-09-03
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: modifications on the pain-threshold in labour and the effects of the epidural analgesia and S-Ketamina on the pai-threshold
    Medical condition: pain-threshold
    Disease: Version SOC Term Classification Code Term Level
    6.1 10029772 HLT
    Population Age: Adults Gender: Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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