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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,334 result(s) found. Displaying page 33 of 2,217.
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    EudraCT Number: 2006-001936-30 Sponsor Protocol Number: Uni-Koeln-687 Start Date*: 2006-09-21
    Sponsor Name:Universität zu Köln
    Full Title: A phase II dose escalation study of caspofungin in patients with invasive aspergillosis
    Medical condition: proven or probable aspergillosis in immunocompromised patients
    Disease: Version SOC Term Classification Code Term Level
    8.1 10003488 Aspergillosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-005742-37 Sponsor Protocol Number: 06/AN/02 Start Date*: 2007-01-26
    Sponsor Name:NHS Glasgow and Clyde / University of Glasgow
    Full Title: Randomised clinical trial of the effects of total intravenous anaesthesia (TIVA: propofol) versus volatile anaesthesia (sevoflurane-N20 induction and isoflurane-N20 maintenance) on children’s post...
    Medical condition: Dental caries
    Disease: Version SOC Term Classification Code Term Level
    8.1 10012318 Dental caries LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-005772-41 Sponsor Protocol Number: LIMIT phase 2 version 1.0 Start Date*: 2006-12-05
    Sponsor Name:investigator-driven research: Erasmus MC, Neurovascular Section
    Full Title: LIMIT: Lowering the Incidence of vascular complications with Metformin in patients with Impaired glucose tolerance and a recent TIA or minor ischemic stroke: a phase 2, randomized, controlled trial
    Medical condition: Patients with impaired glucose tolerance and a recent TIA or minor ischemic stroke
    Disease: Version SOC Term Classification Code Term Level
    8.1 10052426 Glucose intolerance LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-005774-50 Sponsor Protocol Number: 9834p Start Date*: 2007-05-18
    Sponsor Name:Central Manchester & Manchester Children's University Hospitals NHS Trust
    Full Title: Protocol for taking pharmacogenetic testing of tacrolimus into the clinical arena: patient tailored anti-rejection therapy
    Medical condition: The study is to determine whether MDR-1 genotyping correlates with tacrolimus dose in individual patients and could therefore be used in future to predict tacrolimus dose. All patients will have u...
    Disease: Version SOC Term Classification Code Term Level
    8.1 10021510 Immunosuppression NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-005537-11 Sponsor Protocol Number: NCT-2007-11-02-1004 Start Date*: 2011-07-12
    Sponsor Name:University Hospital Heidelberg
    Full Title: Phase I/II intra-patient dose escalation study of vorinostat in children with relapsed solid tumor, lymphoma or leukemia
    Medical condition: Relapsed of progressive solid tumor, lymphoma, or leukemia in children and adolescents aage 3-18 years
    Disease: Version SOC Term Classification Code Term Level
    18.0 10005329 - Blood and lymphatic system disorders 10024324 Leukaemias HLGT
    18.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10025310 Lymphoma PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-005953-49 Sponsor Protocol Number: 26866138MMY 2051 Start Date*: 2009-06-18
    Sponsor Name:Prof. M.A. Dimopoulos
    Full Title: A Prospective, Multicenter, Non-comparative, Open-label, Phase II Study to Evaluate the Effects of the Combination of Bortezomib/Dexamethasone/Zoledronic Acid on Bone Mineral Density, Bone Metaboli...
    Medical condition: This will be a Phase II, prospective, non-comparative, multicenter, open-label study of the effects of the combination of Bortezomib/Dexamethasone/Zoledronic acid on bone mineral density, skeletal ...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10028228 Multiple myeloma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Completed)
    Trial results: View results
    EudraCT Number: 2007-005977-67 Sponsor Protocol Number: GIR1 Start Date*: 2008-02-12
    Sponsor Name:CONSORZIO ONCOTECH
    Full Title: SUNITINIB EITHER BEFORE OR AFTER CYTOREDUCTIVE NEPHRECTOMY A PHASE II TRIAL IN PATIENTS WITH METASTATIC RENAL CELL CARCINOMA
    Medical condition: Patients with metastatic Renal Cell Carcinoma not previously treated with nephrectomy and systemic therapy.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10050018 Renal cancer metastatic LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-006084-73 Sponsor Protocol Number: VIAjectTM-07J Start Date*: Information not available in EudraCT
    Sponsor Name:BIODEL Inc
    Full Title: An Open Label, Multi-Center, Follow-on Study Examining the Long-Term Safety and Efficacy of Insulin VIAjectTM in Subjects with Type 1 Diabetes Mellitus
    Medical condition: Diabetes Mellitus Type 1
    Disease: Version SOC Term Classification Code Term Level
    9.1 10045228 Type I diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-002210-22 Sponsor Protocol Number: COU-AA-003-EXT Start Date*: 2008-09-25
    Sponsor Name:Janssen Oncology, Inc.
    Full Title: An Extended Study of CB7630 (Abiraterone Acetate) in Patients with Advanced Prostate Cancer Who Have Failed Androgen Deprivation and Docetaxel-Based Chemotherapy and Completed Clinical Study COU-AA...
    Medical condition: Hormone refractory prostate cancer
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10062904 Hormone-refractory prostate cancer LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-002009-31 Sponsor Protocol Number: EB069 Start Date*: 2007-06-13
    Sponsor Name:Emotional Brain BV
    Full Title: A double blind randomized placebo controlled cross-over study to validate the distinction between women with different levels of attention and valence direction for erotic stimuli, in relation with...
    Medical condition: Hypoactive sexual desire disorder and female sexual arousal disorder
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2008-007208-28 Sponsor Protocol Number: TROPISMVC Start Date*: 2009-05-06
    Sponsor Name:Asociación para el Estudio de las Enfermedades Infecciosas
    Full Title: Estudio comparativo de dos métodos para predecir el uso de co-receptores por el virus de la inmunodeficiencia 1 (HIV-1): el ensayo fenotípico (Trofile ESTA®) y la respuesta virológica a corto plazo...
    Medical condition: Infección por el Virus de la Inmunodeficiencia Humana tipo-1 (VIH-1). El antirretroviral maraviroc pertenece a un grupo de medicamentos llamados antagonistas del CCR5 e impide la entrada del VIH-1 ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-004970-24 Sponsor Protocol Number: NHL-14 Start Date*: 2008-01-17
    Sponsor Name:AGMT - Arbeitsgemeinschaft Medikamentöse Tumortherapie Gemeinnützige GmbH
    Full Title: Multizentrische Studie über die Cardiotoxizität von R-CHOP (Rituximab, Cyclophosphamid, Doxorubicin, Vincristin und Prednisolon) v. R-COMP (Rituximab, Cyclophosphamid, liposomalem Doxorubicin, Vinc...
    Medical condition: Diffus großzelliges B-Zell Lymphom
    Disease: Version SOC Term Classification Code Term Level
    9.1 10012819 Diffuse large B-cell lymphomas HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2007-004980-23 Sponsor Protocol Number: P05134 Start Date*: 2008-05-05
    Sponsor Name:Schering-Plough Farma, Lda.
    Full Title: Double-Blind evaluation of the safety and efficacy of Quadriderme cream (betamethasone dipropionate, clotrimazole and gentamicin sulphate ) compare with betamethasone dipropionate combined with gen...
    Medical condition: Impetiginous Eczema
    Disease: Version SOC Term Classification Code Term Level
    9.1 10051890 Eczema impetiginous LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: PT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-004985-41 Sponsor Protocol Number: DYSK-PD-2007 Start Date*: 2007-11-29
    Sponsor Name:Department of Neuroscience, neurology
    Full Title: Different dyskinesias in Parkinson's disease and their relation to levodopa pharmacokinetics
    Medical condition: Parkinson's disease, G20.9. Different dyskinesias related to advanced Parkinson's disease will be investigated.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-004994-25 Sponsor Protocol Number: CSMS995A2101 Start Date*: 2008-02-04
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A multi-center, randomized, double-blind, placebo-controlled, crossover study in women with irritable bowel syndrome to evaluate feasibility and reproducibility of barostat assessments of colorecta...
    Medical condition: Irritable Bowel Syndrom
    Disease: Version SOC Term Classification Code Term Level
    9.1 10023003 Irritable bowel syndrome PT
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed) SE (Completed)
    Trial results: View results
    EudraCT Number: 2008-002335-32 Sponsor Protocol Number: AN08/8505 Start Date*: 2008-11-28
    Sponsor Name:The University of Leeds
    Full Title: Does concentration affect the ED50 of bupivacaine for supraclavicular brachial plxus block?
    Medical condition: Not applicable
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-002343-16 Sponsor Protocol Number: 1014/05 Start Date*: 2006-01-05
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: Postoperative nausea and vomiting: acupuncture effect on postoperative prevention
    Medical condition: Postoperative nausea and vomiting laparoscopic cholecistectomy
    Disease: Version SOC Term Classification Code Term Level
    9.1 10008629 Cholelithiasis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-000526-48 Sponsor Protocol Number: A.S.T.R.A. Start Date*: 2007-03-06
    Sponsor Name:AZIENDA OSPEDALIERA POLICLINICO DI MODENA
    Full Title: Randomized, monocentric trial on sintoms, adherence,toxicity of alternate antiretrovirale regimen
    Medical condition: PT HIV-1 positive and naive to antiretroviral drug
    Disease: Version SOC Term Classification Code Term Level
    9.1 10020161 HIV infection LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-001465-14 Sponsor Protocol Number: CSLCT-NHF-06-30 Start Date*: 2007-05-17
    Sponsor Name:CSL Limited
    Full Title: A Single Centre, Open-Label Study to Evaluate the Immunogenicity and Safety of Enzira Vaccine in Healthy Adults aged ≥ 18 to < 60 years and in Healthy Older Adults aged ≥ 60 years for the 2007/2008...
    Medical condition: Prophylaxis of Influenza
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-001187-78 Sponsor Protocol Number: 112897 Start Date*: 2008-01-02
    Sponsor Name:Sheffield Teaching Hospitals NHS Foundation Trust
    Full Title: The 3Mg Trial: A randomised controlled trial of intravenous or nebulised magnesium sulphate versus standard therapy for acute severe asthma
    Medical condition: Acute severe asthma
    Disease: Version SOC Term Classification Code Term Level
    13.1 10038738 - Respiratory, thoracic and mediastinal disorders 10003566 Asthmatic attack LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
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    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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