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Clinical trials for Naloxone

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44344   clinical trials with a EudraCT protocol, of which   7373   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    94 result(s) found for: Naloxone. Displaying page 4 of 5.
    « Previous 1  2  3  4  5  Next»
    EudraCT Number: 2007-001216-23 Sponsor Protocol Number: Clockstop 1, Start Date*: 2007-06-20
    Sponsor Name:Phoenux AG
    Full Title: Phase I Studie bei substituirten chronischen Opiatgebrauchern zur Aufhebung zusätzlicher Opioidwirkungen einer weiteren Opiatgebrauchern zur Aufhebung zusätlicher Opioidwirkungen einer weiteren Opi...
    Medical condition: Opiate addiction
    Disease: Version SOC Term Classification Code Term Level
    9.1 10019935 Heroin addiction LLT
    Population Age: Adults Gender: Male
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-001828-56 Sponsor Protocol Number: NalPilo Start Date*: 2016-12-09
    Sponsor Name:National Institute for Health and Welfare
    Full Title:
    Medical condition: Problem gambling
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004873 10017657 Gambling pathological LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: View results
    EudraCT Number: 2007-002352-41 Sponsor Protocol Number: HDL07-01 Start Date*: 2007-08-21
    Sponsor Name:Helsingin Diakonissalaitos
    Full Title: Lyhyt ja pitkä buprenorfiini-naloksoni -hoito suonensisäisen buprenorfiiniriippuvuuden vieroitushoidossa. Satunnaistettu kontrolloitu tutkimus
    Medical condition: Opiaattiriippuvuus, buprenorfiinin suonensisäinen väärinkäyttö
    Disease: Version SOC Term Classification Code Term Level
    9.1 10030882 Opiate withdrawal symptoms LLT
    9.1 10064475 Opiate dependency relapse LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2021-001817-35 Sponsor Protocol Number: 111958 Start Date*: 2021-08-04
    Sponsor Name:Radboud University Medical Center
    Full Title: Suboxone (buprenorphine/naloxone) versus methadone opioid rotation in patients with escalated opioid use and chronic pain: a randomized trial.
    Medical condition: Opioid use disorder
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2008-003566-26 Sponsor Protocol Number: OXN4501 Start Date*: 2009-02-27
    Sponsor Name:Mundipharma GmbH
    Full Title: An exploratory, randomised, parallel-group, open-label, multicentre study to assess the post-operative management of moderate to severe pain in patients who underwent laparoscopic cholecystectomy, ...
    Medical condition: post-operative management of moderate to severe pain in patients who underwent laparoscopic cholecystectomy
    Disease: Version SOC Term Classification Code Term Level
    9.1 10054711 Postoperative pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-012051-20 Sponsor Protocol Number: OXN 3505 Start Date*: 2009-08-24
    Sponsor Name:Mundipharma
    Full Title: Study of the efficacy of prolonged release oxycodone/naloxone (OXN PR), compared to prolonged release oxycodone (Oxy PR), for the reduction of the intensity of opioid-induced constipation symptoms ...
    Medical condition: For both compounds, treatment for cancer or non-cancer pain, adult subjects with a diagnosis of cancer pain or non-cancer pain such as chronic low back pain, osteoarthritis or other. Only for targi...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10033371 Pain PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2007-005922-62 Sponsor Protocol Number: OXN2501 Start Date*: 2008-05-22
    Sponsor Name:Mundipharma Research GmbH & Co. KG
    Full Title: An exploratory, randomised, active-controlled, double-blind, double-dummy, parallel group pilot study to determine the ability of oxycodone/naloxone prolonged release tablets (OXN) to reduce the nu...
    Medical condition: Opioid induced constipation
    Disease: Version SOC Term Classification Code Term Level
    9.1 10021175 Iatrogenic constipation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) CZ (Completed) HU (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2011-003047-22 Sponsor Protocol Number: RB-UK-11-0017 Start Date*: 2012-01-12
    Sponsor Name:Reckitt Benckiser Pharmaceuticals
    Full Title: A Randomised, Double-Blind, Double-Dummy, Active-Drug-Controlled, Parallel-Group, Multicentre Acceptability and Safety Study of the Transfer from Subutex®/Suboxone® to RBP-6300 in Opioid-Dependent ...
    Medical condition: Maintenance/substitution agent for the treatment of opioid dependence
    Disease: Version SOC Term Classification Code Term Level
    14.1 10037175 - Psychiatric disorders 10012346 Dependence on opiates LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) SE (Completed) CZ (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2013-001540-60 Sponsor Protocol Number: MULTIPAIN6-2013 Start Date*: 2013-08-08
    Sponsor Name:Mech-Sense, Aalborg University Hospital
    Full Title: A novel approach to assess gastrointestinal adverse effects of opioids
    Medical condition: Opioid-induced bowel dysfunction.
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004856 10071128 Opioid induced constipation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2011-003238-15 Sponsor Protocol Number: Schaefers0711 Start Date*: 2012-12-12
    Sponsor Name:KKRN Katholisches Klinikum Ruhrgebiet Nord GmbH
    Full Title: Quality of analgesia and side effect incidence and severity during postoperative pain management with Palexia® compared to Targin®
    Medical condition: Management of postoperative pain in trauma surgery patients (adults) requiring postoperative opiates for the management of postoperative pain.
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004865 10036236 Postoperative pain relief LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-002792-28 Sponsor Protocol Number: 1.7 Start Date*: 2008-08-04
    Sponsor Name:Leiden University Medical Center
    Full Title: Differences in maternal temperature and saturation after administration of remifentanil PCA or epidural analgesia during labor
    Medical condition: laborpain
    Disease: Version SOC Term Classification Code Term Level
    9.1 10052803 Analgesic effect LLT
    Population Age: Adults Gender: Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-005278-71 Sponsor Protocol Number: REMINALO1 Start Date*: 2013-02-26
    Sponsor Name:Helsinki University Central Hospital
    Full Title: The brain opioid system and emotional experiences arising while viewing social interactions.
    Medical condition: Healthy volunteers.
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: FI (Completed)
    Trial results: View results
    EudraCT Number: 2014-000140-15 Sponsor Protocol Number: Neu-rls2014 Start Date*: 2015-02-24
    Sponsor Name:Fondazione Neureca Onlus
    Full Title: Comparative Polysomnographic Study of Oxycodone/Naloxone or Pramipexole for the Treatment of Restless Legs Syndrome
    Medical condition: Restless legs syndrome
    Disease: Version SOC Term Classification Code Term Level
    18.0 10029205 - Nervous system disorders 10058920 Restless legs syndrome PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2012-000839-54 Sponsor Protocol Number: SMi-MW-12 Start Date*: 2012-06-07
    Sponsor Name:Rigshospitalet
    Full Title: The effect of late naloxon-infusion on secondary hyperalgesia after a first degree burn injury
    Medical condition: Induced pain in volunteers
    Disease: Version SOC Term Classification Code Term Level
    14.1 10018065 - General disorders and administration site conditions 10033371 Pain PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-016957-17 Sponsor Protocol Number: OXN4505 Start Date*: 2010-02-03
    Sponsor Name:Mundipharma Oy
    Full Title: A randomised, double-blind, parallel group multicenter study to demonstrate non-inferiority of the analgesic efficacy of oxycodone/naloxone 10/5 or 20/10 mg prolonged release tablets (OXN PR) BID c...
    Medical condition: postoperative pain after knee arthroplasty
    Disease: Version SOC Term Classification Code Term Level
    12.1 10036236 Postoperative pain relief LLT
    12.1 10054711 Postoperative pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: View results
    EudraCT Number: 2010-023025-37 Sponsor Protocol Number: HCA-2010–3 Start Date*: 2011-06-03
    Sponsor Name:Heart Center co.
    Full Title: Oksikodoni-naloksoni kombinaation käyttö sydänleikkauspotilaiden postoperatiivisen kivun hoidossa
    Medical condition: Postoperative cardiac surgery patients
    Disease: Version SOC Term Classification Code Term Level
    13.1 10042613 - Surgical and medical procedures 10036236 Postoperative pain relief LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-015866-71 Sponsor Protocol Number: 2009-10-30 Start Date*: 2009-12-18
    Sponsor Name:Karolinska University Hospital Huddinge
    Full Title: Fast detoxification of opioid addiction in patients suffering from opioids induced hyperalgesi (OIH)
    Medical condition: Patient suffering from opioid induced hyperalgesi (OIH).
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-019892-31 Sponsor Protocol Number: 65759682 Start Date*: 2011-06-15
    Sponsor Name:Lightlake Sinclair Oy
    Full Title: Hoitotutkimus BED-syömishäiriöstä ja sen taustatekijöistä
    Medical condition: Binge Eating-Disorder, BED on ylipainoisilla esiintyvä syömishäiriö, jolle on luonteenomaista ahminta. Tutkimuksessa selvitetään nasaalisen (nenän kautta annosteltavan) naloksonilääkkeen tehoa BES ...
    Disease: Version SOC Term Classification Code Term Level
    13.1 10037175 - Psychiatric disorders 10004716 Binge eating PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-016137-10 Sponsor Protocol Number: 00000000 Start Date*: 2010-01-08
    Sponsor Name:Anne Vakkuri
    Full Title: Lonkan ja polven tekonivelleikkausten yhteydessä käytettävien kipulääkkeiden (Oxycontin, Targiniq) vertailu leikkauksenjälkeisen pahoinvoinnin suhteen
    Medical condition: polven ja lonkan tekonivelleikkauspotilaat
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-004796-39 Sponsor Protocol Number: PT-SM-14-OA Start Date*: 2013-04-30
    Sponsor Name:Fondazione IRCCS Policlinico San Matteo
    Full Title: A Comparative Study of Oxycodone/Naloxone versus Codeine/Paracetamol in the Treatment of Moderate to Severe Chronic Knee and/or hip Pain Due to Osteoarthritis
    Medical condition: Moderate to Severe Chronic Knee and/or hip Pain Due to Osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004859 10023476 Knee osteoarthritis LLT
    14.1 100000004859 10020108 Hips osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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